AEGiS-NYT: Mononucleosis Virus Is Linked to a Cancer New York TimesImportant note: Information in this article was accurate in 1983. The state of the art may have changed since the publication date.
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Mononucleosis Virus Is Linked to a Cancer

The New York Times - October 2, 1983


The same virus that causes mononucleosis may also be responsible for a rare kind of brain cancer that has shown up among victims of acquired immune deficiency syndrome, or AIDS, researchers say.

The doctors said they had found a link between the Epstein-Barr virus and central nervous system lymphoma.

The virus may also cause some other forms of cancer, including Burkitt's lymphoma and nasopharyngeal carcinoma, they said in Thursday's issue of The New England Journal of Medicine.

Only 25 cases of central nervous system lymphoma have been reported in the past 25 years. However, it has recently been seen among victims of AIDS.

In the latest study, doctors found genetic material from the virus in the cancerous part of a victim's brain but not in the healthy tissue. They said four other victims had also shown signs of recent infection with the virus. None of the five patients had AIDS.

"Our results suggest induction of the lymphoma by Epstein-Barr virus," the doctors wrote.

The study was directed by Dr. Fred H. Hochberg at Massachusetts General Hospital.

Doctors elsewhere are working on a vaccine that would prevent illnesses causes by Epstein-Barr viruses, including mononucleosis, an infection that often strikes college students and other young people.


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