Important note: Information in this article was accurate in 2004. The state of the art may have changed since the publication date.
Bangkok Post - June 8, 2004
Apiradee Treerutkuarkul
Disease Control Department director-general Charal Trinvuthipong said yesterday that of 6,000 volunteers, 4,000 had so far been injected with the vaccine.
The trial aims to involve about 16,000 volunteers in two eastern provinces of Chon Buri and Rayong, who will be given either a vaccine or a placebo over a one-year period, to be followed up for three years.
The US-sponsored Aids vaccine trail started in Thailand last September.
The so-called prime-boost test combines two vaccines: Alvac, which was created by France-based Aventis Pasteur, and AidVAX B/E, which is made by the California-based VaxGen Inc, to stimulate different systems of immune response simultaneously.
In previous human tests, one vaccine failed twice and the other's usefulness in stimulating the immune system is not known. The authorities hope that putting the two together might be an effective alternative to HIV/Aids control.
Dr Charal said the department would continue with the experiment because a vaccine made from the virus E subtype was the most prevalent strain in Thailand.
The progess of the phase-3 trial would also be discussed at the International Aids Conference held in Bangkok from July 11-17.
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