AEGiS-BBC: Green tea extract may fight HIV BBC News OnlineImportant note: Information in this article was accurate in 2003. The state of the art may have changed since the publication date.
Click here to return to BBC News Online main menu
DonateNow
Print this article

Green tea extract may fight HIV

BBC News - November 10, 2003


Green tea could form the basis of a new generation of HIV drugs, say experts. Scientists in Japan have found a component of green tea can stop HIV from binding to healthy immune cells, which is how the virus spreads.

Their laboratory tests suggest a chemical called Epigallocatechin Gallate (EGCG) protects cells.

Writing in the Journal of Allergy and Clinical Immunology, the scientists said the discovery could lead to new treatments to fight the disease.

Key chemicals

Green tea is made up of a class of chemicals called catechins, the most abundant of which is EGCG.

It is believed that EGCG is responsible for green tea's health benefits.

Previous studies have suggested it can protect against a range of diseases, including cancer and heart disease.

Dr Kuzushige Kawai and colleagues at the University of Tokyo carried out tests to see if the chemical could help beat HIV.

They found that EGCG stopped the virus from binding to CD4 molecules and human T cells.

These are vital parts of the body's immune system. Usually HIV is able to sneak inside these cells and wipe them out.

The scientists said further research is needed to see if EGCG could be used in new anti-HIV drugs.

They said simply drinking green tea would not offer people protection from the virus.

The concentration of EGCG used in the laboratory tests are many times over the blood concentration that could be achieved by just drinking green tea.

But in an accompanying editorial, Dr William Shearer from Baylor College of Medicine in Houston, Texas, welcomed the findings.

"Molecular modelling of a drug form of EGCG for HIV infection might be a further development of these investigations," he said.

Previous studies have also indicated this chemical may have a role to play in fighting HIV.

However, much further research is needed before the laboratory findings will lead to drugs for patients with HIV.


031110
BB031105


Copyright © 2003 - BBC. Reproduction of this article (other than one copy for personal reference) must be cleared through the BBC.

AEGiS is a 501(c)3, not-for-profit, tax-exempt, educational corporation. AEGiS is made possible through unrestricted funding from Boehringer Ingelheim, Bridgestone/Firestone Charitable Trust, Elton John AIDS Foundation UK, the National Library of Medicine, AIDS Walk of Orange County, and donations from users like you.

Always watch for outdated information. This article first appeared in 2003. This material is designed to support, not replace, the relationship that exists between you and your doctor.

AEGiS presents published material, reprinted with permission and neither endorses nor opposes any material. All information contained on this website, including information relating to health conditions, products, and treatments, is for informational purposes only. It is often presented in summary or aggregate form. It is not meant to be a substitute for the advice provided by your own physician or other medical professionals. Always discuss treatment options with a doctor who specializes in treating HIV.

Copyright ©1980, 2003. AEGiS. All materials appearing on AEGiS are protected by copyright as a collective work or compilation under U.S. copyright and other laws and are the property of AEGiS, or the party credited as the provider of the content.

.