Are European-Specific Guidelines Needed for Prevention of Opportunistic Infections in HIV-1? CDC Daily UpdateImportant note: Information in this article was accurate in 1999. The state of the art may have changed since the publication date.

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Are European-Specific Guidelines Needed for Prevention of Opportunistic Infections in HIV-1?

Lancet (10/09/99) Vol. 354, No. 9186, P. 1305
Yazdanpanah, Yazdan; Goldie, Sue J.; Salamon, Roger; et al.


A letter to the editor of the Lancet discusses the need for European-specific guidelines for the prevention of opportunistic infections in HIV-1-infected patients. Researchers surveyed 49 coordinators of AIDS surveillance in the World Health Organization European region. Of the 30 coordinators who responded, 14 percent supplied their own nation-specific guidelines, including recommendations similar to those from the U.S. Public Health Service and the Infectious Disease Society of America (USPHS/IDSA) with key exceptions. However, 25 coordinators said their countries had no national guidelines, with 16 saying they followed the USPHS/IDSA recommendations and two reporting that they used guidelines established by specialized HIV/AIDS units in university centers. The authors note that U.S. guidelines may not be directly transferable to patients in Europe, since practice settings and patient populations may be different. Local data on opportunistic infections can be put into decision analytical models to estimate the efficacy and cost- effectiveness of site-specific recommendations, the researchers said.


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