AIDS Vaccines Look Good in Tests

Important note: Information in this article was accurate in 1998. The state of the art may have changed since the publication date.

AIDS Vaccines Look Good in Tests

San Francisco Examiner Online (12/27/98)
Rosenberg, Eric

Even though several AIDS experts are confident that developing a vaccine against AIDS by President Clinton's goal of 2007 is an attainable objective, a 1998 National Institutes of Health report that said that creating an effective vaccine will require a tremendous undertaking has received the support of researchers such as R. Scott Hitt, chairman of Clinton's advisory council on HIV/AIDS, who believes that developing a vaccine within 10 years will take more effort or good luck. Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases and an advocate of Clinton's goal, has pointed out that one of three vaccines in late-stage development could be the first to make a breakthrough, including VaxGen's AIDSVax, which is in Phase III trials to determine whether the antibodies stimulated by the genetically engineered vaccine attack HIV. Using a different approach, Wyeth-Lederle Vaccines is developing a vaccine that involves injecting a small amount of HIV DNA into a person's muscle to stimulate the production of antibodies against the virus. Pasteur-Merieux Connaught is working on a so-called vectored vaccine, currently in Phase II trials, that could be tested on thousands of patients in a Phase III trial beginning next year.

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