Antenatal Screening for Syphilis CDC Daily UpdateImportant note: Information in this article was accurate in 1998. The state of the art may have changed since the publication date.

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Antenatal Screening for Syphilis

British Medical Journal Online (12/12/98) Vol. 317, No. 7173, P. 1605
Welch, Jan


Cases of congenital syphilis in the United Kingdom are rare, but syphilis is the only chronic infection for which women are routinely screened during pregnancy, writes Jan Welch, of the Department of Sexual Health of King's Healthcare NHS Trust in London, in an editorial. Some healthcare centers are considering discontinuing screening due to the dearth of cases. However, Welch argues that instead of abandoning screening, "we should ensure that we have an effective national program, with standards for the screening, diagnosis, and management of expectant mothers and their infants." Welch cites a study appearing in the same journal which found that 139 women were treated for syphilis in pregnancy in Britain over the three-year course of the study. Thirty-one of the women had early, congenitally transmissible infections, and there were nine identified cases of congenital syphilis. From a financial standpoint, the author notes that cessation of antenatal screening would save about 660,000 pounds. However, at least 10 women with early syphilis would be missed annually, resulting in fetal deaths and congenital disease. The program also serves as an early warning system for adult infection, while cost-benefit analysis shows that antenatal screening is worthwhile even in the areas with the lowest syphilis prevalence.


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