Transfusions and Kids: The Deadly HIV Link in Africa CDC Daily UpdateImportant note: Information in this article was accurate in 1997. The state of the art may have changed since the publication date.

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Transfusions and Kids: The Deadly HIV Link in Africa

AIDS Alert--International (12/97) Vol. 12, No. 12, P. 1


Abstract: Many HIV infections in developing nations, especially those in young children, are the result of contaminated blood transfusions. However, experts note that very few resources have been dedicated to prevention efforts in these areas. According to the Centers for Disease Control and Prevention's Eve Lackritz, such basic remedies as improving blood-screening and blood-banking practices, reducing the number of unnecessary transfusions, and treating malaria with different drugs could play a key role in reducing infection. "Everyone still feels HIV is primarily a sexually transmitted disease, and that blood transfusions aren't driving the epidemic," said Lackritz. As a result: "very little support is going into this very preventable problem." Although the exact number of transfusion-related infections is not known, one Congo study found that blood transfusions were to blame for one-quarter of HIV cases among infants and for 42 percent of HIV infections in children one year and older. Confounding the problem are a lack of resources; frequent transfusions for anemia, which can be caused by malaria; and inappropriate transfusions. According to Lackritz, using new drugs for malaria--which causes 5,000 deaths a day in Africa--could reduce the need for so many transfusions. Lackritz recommends using a combination of pyrimethamine and sulfadoxine instead of the standard chloroquine therapy, to which many malaria infections in eastern Africa are resistant.


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