Anti-HHV-8 Agents Identified as Candidates for AIDS-Related KS Prevention

Important note: Information in this article was accurate in 1997. The state of the art may have changed since the publication date.

Anti-HHV-8 Agents Identified as Candidates for AIDS-Related KS Prevention

Reuters Health Information Services (12/18/97)

Abstract: Johan Neyts and Erik de Clercq of Belgium's Rega Institute report in the December issue of Antimicrobial Agents and Chemotherapy that they have identified four agents with "marked anti-HHV-8 activity": cidofovir, ganciclovir, foscarnet, and adefovir. The researchers also note that if HHV -8 can be blocked and is the etiological factor in Kaposi's syndrome--commonly seen in HIV-positive patients--and primary effusion lymphoma, the load of the virus may be kept too low to cause HHV-8-related malignancies. Based on in vitro studies of the four agents, the researchers suggest that molecules currently used as anti-HIV agents may be effective against HHV -8 and may offer useful information for prophylactic use among the HIV-positive population that is at risk of HHV-8 infection.

971222
AD972328

Copyright © 1997 - Information, Inc., Bethesda, MD. The CDC National Center for HIV, STD and TB Prevention provides the following information as a public service only. Providing synopses of key scientific articles and lay media reports on HIV/AIDS, other sexually transmitted diseases and tuberculosis does not constitute CDC endorsement. This daily update also includes information from CDC and other government agencies, such as background on Morbidity and Mortality Weekly Report (MMWR) articles, fact sheets, press releases and announcements. Reproduction of this text is encouraged; however, copies may not be sold, and the CDC HIV/STD/TB Prevention News Update should be cited as the source of the information. Contact the sources of the articles abstracted below for full texts of the articles.

AEGiS is a 501(c)3, not-for-profit, tax-exempt, educational corporation. AEGiS is made possible through unrestricted funding from Boehringer Ingelheim, Bridgestone/Firestone Charitable Trust, Elton John AIDS Foundation, the National Library of Medicine, AIDS Walk of Orange County, and donations from users like you.

Always watch for outdated information. This article first appeared in 1997. This material is designed to support, not replace, the relationship that exists between you and your doctor.

AEGiS presents published material, reprinted with permission and neither endorses nor opposes any material. All information contained on this website, including information relating to health conditions, products, and treatments, is for informational purposes only. It is often presented in summary or aggregate form. It is not meant to be a substitute for the advice provided by your own physician or other medical professionals. Always discuss treatment options with a doctor who specializes in treating HIV.

Copyright ©1980, 1997. AEGiS. All materials appearing on AEGiS are protected by copyright as a collective work or compilation under U.S. copyright and other laws and are the property of AEGiS, or the party credited as the provider of the content.