Scientists Advance in Understanding AIDS Enzymes

Important note: Information in this article was accurate in 1994. The state of the art may have changed since the publication date.

Scientists Advance in Understanding AIDS Enzymes

Reuters (12/22/94)

Researchers at the National Institute of Diabetes and Digestive and Kidney Diseases announced on Thursday the discovery of the three-dimensional structure of one of the three key enzymes that HIV needs to reproduce. The finding fills in a large gap in the knowledge of researchers trying to develop a treatment or cure for AIDS. Knowing the structure of the enzyme may help in the development of a drug that could block it. Researchers are trying to develop drugs that target the three HIV enzymes, but HIV has a tremendous ability to mutate and evade treatments. Scientists hope to develop several drugs that can be used in a multi-drug "cocktail" to target the enzymes

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