"U.S. Patents Are Granted for 3 Laboratory Mice" CDC Daily UpdateImportant note: Information in this article was accurate in 1992. The state of the art may have changed since the publication date.

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"U.S. Patents Are Granted for 3 Laboratory Mice"

Washington Post (12/30/92), P. A4


Abstract: The federal government granted three patents yesterday to strains of genetically altered mice. Researchers consider the patents critical for biotechnology. They are the first since 1988 to recognize ownership of a genetically altered animal species. The U.S. Patent and Trademark Office (PTO) notified its Official Gazette that it was issuing patents for laboratory mouse strains to Harvard University, GenPharm International of Mountain View, Calif., and Ohio University. GenPharm was granted a patent for a mouse strain that has been altered so that it naturally fails to develop a fully functional immune system. The GenPharm mouse was genetically altered by the addition of aJgene that prevents the rodent from developing fully mature lymphocytes. The new mouse will be used in the study of immune-system diseases such as AIDS, or in research on autoimmune diseases, said Jonathan MacQuitty, chief operations officer of GenPharm.


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