"Cerebral Pneumocystis Carinii Infection in AIDS" CDC Daily UpdateImportant note: Information in this article was accurate in 1991. The state of the art may have changed since the publication date.

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"Cerebral Pneumocystis Carinii Infection in AIDS"

Lancet (12/22-29/91) Vol. 336, No. 8730, P. 1592
Mayayo, E., et al.


Abstract: A 30-year-old IV drug user with AIDS had cerebral Pneumocystis carinii infection, a previously unrecorded condition, write E. Mayayo and colleagues of the University of Barcelona, Spain. Although extrapulmonary pneumocystis has been reported in the retina, bone marrow, small intestine, thyroid, and skin, infection of the brain is new. The patient complained of fever, headache, somnolence, moderate disorientation, and weakness. Doctors diagnosed cerebral toxoplasmosis, but subsequent study revealed pneumocystis with occasional toxoplasma cysts. The patient was at risk for P. carinii dissemination because his T4 cell count was below 400 and he was not receiving prophylaxis. The result was multiple opportunistic infections of the central nervous system, Mayayo and colleagues conclude.


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