"Genelabs AIDS Drug Safe in Clinical Tests" CDC Daily UpdateImportant note: Information in this article was accurate in 1991. The state of the art may have changed since the publication date.

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"Genelabs AIDS Drug Safe in Clinical Tests"

Investor's Business Daily (12/17/91), P. 30


Abstract: Genelabs Technologies Inc. said yesterday that its treatment for AIDS, GLQ223, has proven safe and clinically well-tolerated in its Phase I results. Genelabs said the clinical study showed that GLQ223, or alpha-trichosanthin, was effective when given to AIDS patients or those with AIDS-related complex. The drug was well tolerated and was linked with measurable increases in markers of immunological activity. Twenty-one patients with AIDS or ARC were administered four weekly infusions of GLQ223. According to the company, the patients with the two highest doses experienced the best results in immunologic markers. The Phase II trial started in September and will comapare and combine GLQ223 with AZT.


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