"Tuberculosis and HIV Infection"

Important note: Information in this article was accurate in 1991. The state of the art may have changed since the publication date.

"Tuberculosis and HIV Infection"

New England Journal of Medicine (12/26/91) Vol. 325, No. 26, P. 1882
Stead, William W. and Lofgren, John P.

Abstract: Barnes et al. (New England Journal of Medicine--June 6) failed to recognize in their article on tuberculosis patients with HIV the manner in which HIV infection accelerates the development of tuberculosis when tuberculin-negative HIV-positive indificuals are infected by Mycobacterium tuberculosis. William Stead and John Lofgren of the Arkansas Department of Health write that recent reports indicate that active tuberculosis may significantly increase the progression of HIV infection. Hospitals and clinics providing care for persons with HIV should therefore use upper-air sterilization by the germicidal portion of the ultraviolet spectrum. If air recirculation continues to occur air should be irradiated with germicidal ultraviolet light or filtered through a high efficiency particulate air filter. This would exhaust all resources to prevent the transmission of tubercle bacilli to particularly susceptible individuals. Taking action would be especially important as the spread of organisms resistant to multiple drugs become more prevalent, the researchers conclude.

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Copyright © 1991 - Information, Inc., Bethesda, MD. The CDC National Center for HIV, STD and TB Prevention provides the following information as a public service only. Providing synopses of key scientific articles and lay media reports on HIV/AIDS, other sexually transmitted diseases and tuberculosis does not constitute CDC endorsement. This daily update also includes information from CDC and other government agencies, such as background on Morbidity and Mortality Weekly Report (MMWR) articles, fact sheets, press releases and announcements. Reproduction of this text is encouraged; however, copies may not be sold, and the CDC HIV/STD/TB Prevention News Update should be cited as the source of the information. Contact the sources of the articles abstracted below for full texts of the articles.

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