"Lab Notes: New Contraceptives Use Sperm-Killing Antibodies" CDC Daily UpdateImportant note: Information in this article was accurate in 1990. The state of the art may have changed since the publication date.

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"Lab Notes: New Contraceptives Use Sperm-Killing Antibodies"

Wall Street Journal (12/20/90), P. B1
Waldholz, Michael


Abstract: Johns Hopkins University researchers have used antibodies in a contraceptive to prevent pregnancy and perhaps fight sexually transmitted diseases. Based on the finding that some couples are infertile because women produce antibodies that deactivate their partners' sperm, researchers Richard Cone and Kevin Whaley produced genetically-engineered antibodies delivered in a controlled-release form in a plastic vaginal ring. The contraceptive could stay in place for months and prevent sperm from travelling beyond the cervix. In mice, the antibodies prevented infection with genital herpes.


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