"Government Study Shows Failure of Bone Marrow Transplants in"

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"Government Study Shows Failure of Bone Marrow Transplants in"

Associated Press (12/21/89)
Raeburn, Paul

Abstract: New York--Bone marrow transplantation has thus far been a failure in treating people with AIDS, according to an unpublished government study of 16 people with the disease. On Tuesday, the New York Times reported that a research team from Johns Hopkins University found that a combination of bone marrow transplant and AZT appeared to wipe out HIV in a patient. The patient died before scientists could confirm the results. On Wednesday, Dr. Clifford Lane, who led a study of 16 patients for the National Institute of Allergy and Infectious Diseases, said his study produced "16 failures." The researchers, Lane said, found "only transient improvement in immunity in patients getting AZT." Patients in Lane's study were identical twins, so each patient had a perfect bone marrow match with his twin. In the Johns Hopkins study, the researchers did not work with twins, and thus had to "ablate," or destroy the patient's immune system before the transplant. Other researchers said the costly treatments deserve further study.

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