Mail & Guardian (Johannesburg) - August 13, 2003
Double trouble: Researchers at the University of Cape Town have found further evidence suggesting that patients infected by more than one strain of HIV before seroconversion - when the body starts to produce antibodies to the virus - are more likely to progress rapidly to Aids.
Earlier this year researchers at the University of Washington reported similar findings in four individuals with dual HIV infection who had progressed to Aids or death within two years of infection.
Dual infection can be a consequence of co-transmission, infection with two strains at the same time, or superinfection, when a second HIV infection occurs in an already infected person. The two viruses may be from the same subtype, though genetically highly divergent from each other.
People who become infected during unsafe sex with multiple partners could potentially have a very different clinical outcome from those who become infected during the occasional unsafe sexual encounter.
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