Important note: Information in this article was accurate in 1987. The state of the art may have changed since the publication date.
Report on Informal Discussions on AIDS Vaccine Efficacy Trials in Human Populations
AIDS & Public Policy Journal 2, no. 2 (Spring-Summer 1987): 62-65. World Health Organization
The World Health Organization has recognized a responsibility to assume a lead role in global efforts to combat the pandemic of infection with the human immunodeficiency virus (HIV). Current prevention and control efforts are focused primarily on health education and communications and on HIV antibody screening of blood for transfusion. However, a safe and effective vaccine to prevent HIV infection would be a significant addition to prevention programmes. In anticipation of the need for clinical testing of candidate vaccines, the WHO Programme on AIDS organized an informal meeting held in Geneva from 15 to 16 December 1986, to discuss AIDS vaccine efficacy trials in human populations. Dr. Halfdan Mahler, Director-General of the World Health Organization, welcomed the participants, stressed the importance of scientifically rigorous human efficacy trials of any vaccine, and emphasized that failure to prepare in advance for such trials involving AIDS vaccines could seriously delay vaccine availability to the entire world. The participants were asked to identify areas of potential concern in clinical trials and to make recommendations to WHO about its role in helping to anticipate and address these issues.
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