ADAP drugs: cyproheptadine hydrochloride

cyproheptadine hydrochloride (Periactin)

Drug description
Periactin is an antihistamine that comes in syrup and pill form. Periactin also has sedative effects and calcium-channel blocking activity. Periactin is used to treat some hormonal disorders, including inhibited orgasm that may be a side effect of taking antidepressants. Periactin has also been shown to stimulate appetite and weight gain in children and adults. Periactin is sometimes used as an adjunct therapy in children who are taking human growth hormone.

Side effects
Side effects occur with all antihistamines and will vary between individuals. Mild drowsiness to deep sleep is not unusual. Dizziness, low energy, disturbed coordination, and muscular weakness may occur. Children may get over-excited and even have seizures. Nausea, vomiting, diarrhea or constipation may occur. Other side effects include dryness of the mouth, nose and throat, trouble urinating, vertigo, blurred vision, tightness of the chest, wheezing, stuffed nose, sweating, chills, early period, headaches, and faintness.

Dosage
Dosage must be determined individually according to each personís response and tolerance. For the management of weight loss, adults and children 13 years and older usually start with 2 mg 4 times daily which is gradually increased over 3 weeks up to 8 mg 4 times daily.

How long it may take to work
Response to treatment depends on the condition being treated.

Managing side effects
Avoid alcohol. If you are already taking sedatives or tranquilizers, consult with your doctor about possible drug interactions. Gastrointestinal symptoms may be decreased by taking the drug with meals or with milk. Do not take if you have asthmatic attacks. Safety during pregnancy has not been established. The drug should not be taken by mothers who are breast feeding.

This information is specific to the use of this medication for HIV-related conditions. For additional information about this drug for other conditions, refer to: www.nursespdr.com/

The drug descriptions on these pages are intended for informational purposes only. The Network does not promote or endorse the use of any specific treatment for any health-related condition. The medications described here can only be dispensed by a licensed health care professional. The information may have changed since these pages were updated, though every effort is made to keep these pages current. Please contact The Network at (800) 734-7104 to make sure you have the most up-to-date information

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