15th International AIDS Conference

Bangkok, Thailand — July 11-16, 2004

Cite as: Int Conf AIDS. 2004 Jul 11-16;15:Abstract No. xx

Track B - Table of Contents
Monday Tuesday Wednesday Thursday Late-Breakers
Track A Track B Track C Track D Track E

Living well with HIV/AIDS at home in resource poor settings of Amritsar.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10002); Bharti R, Bharti P;;;; BDC Research Ceter,AAG, Amritsar, India; HIV already has 4.6 m victims (Officially) in India and everyone in authority or otherwise knows that managing these victims and their problems by government efforts alone is like trying to reach moon on foot. Despite the increasing numbers the basic issues remain to be solved. The issues are-are these numbers
Research on different manifestations of STDs/HIV/AIDS in one of the high prevalent districts in India.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10008); Ovung Mhabemo E;;;; Hospital, Dimapur, India; Nagaland is situated in the northeastern part of India bordering Myanmar . It is one of the sixth high prevalent states in India. Dimapur is the commercial hub of Nagaland and it has the highest prevalence of HIV/AIDS/STDs in Nagaland. The ongoing campaign against HIV/AIDS/STD at Dimapur is gaini
Linking Agro-chemicals and HIV AIDS to Learning Disabilities in Kenya.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10013); Waikwa SW;;;; Itemeini Organic Farming Self Help Group, Othaya, Kenya; Background. Agro-chemicals and their subsequent abuse are greatly contributing to learning and development disabilities to children affected by the HIV AIDS scourge in Kenya . In the recent past, it has been noted that agro-chemical abuse has seen to the rise of multiple problems to children of school age who are eithe
Management of HIV Kaposi's sarcoma in South Africa: a prospective, randomised, open-labelled trial comparing the response to HAART with the combination of HAART and chemotherapy (CXT) Preliminary results of 32 patients.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10019); Mosam A, Coovadia HM, Cassol S, Friedland GH, Scadden DT, Cassol E, Page T, Bodasing U, Dawood H, Aboobaker J, Jordaan JP, Lalloo UG;;;; Nelson R Mandela, Durban, South Africa; HAART has decreased the incidence of Kaposi s sarcoma (KS) in the West and has been successful as therapy in isolated reports. There are no prospective trials on HAART as KS therapy. 1. To document the clinical response of HIV KS to HAART ( d4T ,
Is combination: indinavir (400 mg bid) plus boosting dose of ritonavir (100 mg bid) safe enough?: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10024); Dragovic G, Jevtovic DJ;;;; Department of Clinical Pharmacology, Pharmacology and Toxicology; Efficacy of Indinavir (IDV) has been known for more than 6 years. Its major disadvantages are limited absorption, a short elimination half-life and adverse events such as nephrolithiasis. IDV in combination with ritonavir (RTV) is believed to ameliorat
Mentality of PLWHA and affected families in the slum-based poorest of poor community.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10029); Swamy GA, Swamy KG;;;; John Paul Slum Development Project, Pune , India; John Paul Slum Development Project is secular voluntary organisation basically working for the well being of slum dwelling PLWHA in Pune- India for those who are socially-economically downtrodden and neglected by the community wherein prevalence and incidence rate is on hike day to day due to their ignoran
The Psychological aspects of HIV testing in African children.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10034); Kwalombota KM, Shumba CD;;;; Ndola Central Hospital, Ndola, Zambia; OBJECTIVES: HIV testing in paediatrics is standard practice. The psychological consequence of a positive test in a child can be far reaching. It maybe worse in resource limited settings, because only minimal interventions are taken in the management of the children. The study tried to find out the factors that can infl
Mother to child hiv transmission: investigating the role of psychosocial factors in risk reduction among newly HIV infected pregnant women in nigeria: preliminary report.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10039); Olley BO;;;; Department of Psychology, Faculty of the Social Sciences, University of Ibadan.l, Ibadan, Nigeria; Objectives: Several programs have been launched by international government and agencies to offer short course antiretroviral drug regimens to reduce mother-to-child transmission (MTCT) of HIV. There is, for example, growing evidence that stress, negative life events and psychopathology contribute significantly to the
An evaluation of direct observed therapy (DOT) Programme at Mukono AIDS Project.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10044); Sewanyana SV;;;; University, Kampala, Uganda; To assess impact of direct observed therapy programme on rate of infection and cure of T. B among HIV/AIDS patients. In 2001 Mukono AIDS project started a DOT programme as a means of ensuring compliance and adherence to T. B treatment among HIV/AIDS patients attending our clinic abaseline survey
Antiretroviral resistance mutations among HIV positive pregnant women.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10049); Edeh CN, Babaoye G;;;; HEAL Concept, Abuja, Nigeria; AZT has been routinely offered to HIV pregnant women to prevent HIV transmission from mother to child. Multi-drug ARV regimens are increasingly used for treatment. Viral resistance and its relative role in vertical; transmission and subsequent pediatric clinical course are important to understand especially
HIV Kaposis sarcoma in a Mother Child Pair.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10053); Mosam A, Thejpal R, Goga Y, Page T, Cassol E, Coovadia HM, Cassol S;;;; Nelson R Mandela School of Medicine, Durban, South Africa; The simultaneous occurrence of KS in mother-child pairs has been documented in only 2 other case reports from Zimbabwe and Zambia . We report the occurrence of KS in mother and child pair from South Africa co-infected with HIV 1 Clade C and Human Herpesvirus 8 (HHV 8) subtype B viral infectio
HIV-1 and hepatitis B and C multiple infection are common in Cameroon.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10058); Ngansop Charlotte NC, Kobayashi Eiji KE, Ndembi Nicaise NN, Takemura Taichiro TT, Ido Eiji IE, Takeda Katsumichi TK, Hayami Masanori HM, Kaptue Lazare KL, Ichimura Hiroshi IH;;;; Faculty of medicine and biomedical sciences, university of yaounde I yaounde Cameroon, Yaounde, Cameroon; There has been reported about the prevalence of hepatitisCvirus (HCV) and hepatitis B virus(HBV)in Cameroon . HCV antIbody tets have been reported to miss as much as 39% of HCV infections in prson co-infected with HIV. In this study, to know HIV whether HIV infection can influence onthe infecti
Haematogical and Biochemical Response to treatment of HIV-1 infection with a combination of Nevirapine + Stavudine+ lamivudine in Lagos Nigeria.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10064); Odunukwe NN, Idigbe EO, Adewole TA, Onwujekwe DI, Audu R;;;; Clinical Research Centre Nigerian Instituteof Medical Research, Fedral Ministry of Health, Lagos , Nigeria; To evaluate the effect of a combination of Nevirapine +Stavidine + Lamivudine on Heamatogical and Biochemical values of HIV-1 positive patients in Lagos. Methods and materials: Fifty patients who met the enrollment criteria for accelera
Expression of gp120 as a surrogate marker in HIV infection.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10068); Escobar Guevara EE, Monzon de Orozco AO, Mantilla Guevara P, Ochoa Diaz M, Pacheco ME, Marcano de Heras EJ;;;; Bio Cell Laboratory, Caracas, Venezuela; To evaluate the expression of HIV-1 s gp120 in peripheral blood CD4+ T lymphocytes of infected patients as a surrogate marker of disease progression. Methods: Ninety seven patients infected with HIV were studied, analyzing correlation of viral load, T cell subsets, expression of activation markers, antiretr
Cytolin is effective in reducing viral burden.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10073); Northfelt DW, Allen A;;;; Mayo Clinic Scottsdale, Scottsdale, United States; Cytolin® is an anti-LFA-1 monoclonal antibody (mAb) that may reversibly inhibit CD8+ CTL killing of CD4+ T cells; thus, reducing HIV viral load. Cytolin® has no effect on the virus - its method of action is to enhance immunocompetence; thus, evolution of virus subspecies has no effect on the effic
Expression of Interlukin-2Rialpha Chain (CD25) on Peripheral Blood Lymphocytes in HTLV-I Associated Myelopathy/ Tropical Spastic Paraparesis Patients.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10078); Nobahar V, Farid R, Farid F, Abbaszadegan M, Mahmoudi M, Rasteen M;;;; Mashhad University of Medical Sciences, Mashhad, Islamic Republic of Iran; Mashhad, a city in northern Iran , is a newly recognized endemic area for a retrovirus, the Humsn T-cell Lymphotropic Virus Type I (HTLV-I). This virus is the causative agent of a chronic slowly progressive cord syndrome called HTLV-I associated with Humsn T-cell Lymphotropic Virus Type I-asoociated myelopa
Pattern and outcome of Neurological manifestations of HIV/AIDS - a review of 154 cases in a Nigerian university teaching hospital.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10083); Ogun SA, Ojini FI, Okubadejo N, Danesi MA, Kolapo KO, Osalusi BS, Brian boyle B;;;; Ogun state university teaching hospital Sagamu, Sagamu, Nigeria; The HIV is neurotropic and clinicians need to be aware of its myriad neurologic manifestations, as these may be the only clinical presentation. This retrospective study aims to evaluate the clinical spectrum and outcome of the neurologic manifestations in patients with HIV / AIDS over a ten year period. Met
Spectrum and Outcome of Clinical Diseases In Adults Living With AIDS At The Ogun State University Teaching Hospital. - A - Ten Year Review.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10088); Ogun SA, Adelowo OO, Familoni OB, Adefuye OB, Alebiosu C, Jaiyesinmi AE, Fakoya EA, Odusan B, Odusoga OL, Ola OO;;;; Ogun State university teaching hospital Sagamu, Sagamu, Nigeria; The HIV epidemics continue to spread and there is dearth of information on the incidence / prevalence, natural history, pattern and progression of the disease in resource poor settings. It is with this background that this retrospective study was carried out to evaluate the changing frequency of HIV / AIDS
Treatment, care and support for prevention - A model projects amongst injecting drug users (IDUs) in Nepal.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10094); Shah S, Rana BJ, Rana PS, Kafle S, Shrestha PK;;;; Nava Kiran Plus, Kathmandu, Nepal; Nepal has one of the fastest growing rate of HIV infection in South Asia. With an estimated 60 000 person living with HIV/AIDS the epidemic is concentrated in IDUs which has a staggering HIV prevalence rate of 68% in the capital and more than 40% in general. Lack of immediate targeted intervention may result in
Antiretroviral (ARV) therapy in a community based support group for people living with HIV/AIDS (PLWHA) in Nepal.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10099); Shrestha R, Kc M, Rana A, Kc J, Thapa S, Thapa SM, Karki T, Thapa D, Rana B, Pun G;;;; Nava Kiran Plus, Kathmandu, Nepal; WHO/ UNAIDS estimates that 60 000 people are living with HIV/AIDS in Nepal . Due to poor economic conditions and lack of health care services most of them cannot access ARV therapy. Support groups for PLWHAs can play a vital role in implementing community based ARV treatment programs.
Efficacy of amphotericin B in a fat emulsion for the treatment of cryptococcal meningitis in AIDS patients.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10104); Gongora-Rubio F, Gongora DV, Zanon JR;;;; Hospital de Base - Funfarme/ Infectious Diseases Department - Famerp, Sao Jose do Rio Preto -SP, Brazil; Several formulae have been developed in an effort to reduce the toxicity of amphotericin B (Amb), but their high costs preclude widespread use. To evaluate the efficacy of Amphotericin B in a fat emulsion, i.e. Intralipid (Amb-IL) in 37 AIDS patients with cryptococcal meningitis (CM). Patients and methods:
Serological responses to hepatitis B vaccination in HIV infected patients.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10109); Gongora DV, Gongora-Rubio F, Onishi E, Ferreira LC;;;; Hospital de Base - FUNFARME/ Infectious Diseases Department - FAMERP, Sao Jose do Rio Preto -SP, Brazil; Hepatitis B prevention in HIV carriers is important owing to the greater risk of developing the chronic disease and evolving to hepatic cirrhosis earlier than other individuals. The aim of this study was to investigate which population is susceptible to the hepatitis B virus (HBV) amo
Detection of HIV-1 antibody using an indirect immunofluorescence assay based on L-2 cell line.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10113); Lai W, Yin Y;;;; Institute of Dermatology, Chinese Academy of Medical Sciences, Nanjing, China; With the increase in the prevalence of human immunodeficiency virus (HIV) infection in China , there is an urgent need to explore cost-containing methods of HIV antibody detection. L-2 cell line is a T cell line persistently infected with a mutant HIV-1 subtype B strain and come from MT-4 cell line by origi
ProTEST: A vehicle for delivery of ARV's in high burden, resource poor settings?: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10118); Ginwalla R, Ayles H, Sibande MN, Shanaube K, Siwale M, Kankasa C, Godfrey-Faussett P;;;; ZAMBART, University Teaching Hospital, Lusaka, Zambia; Many resource poor countries with a high burden of HIV are scaling up access to antiretroviral drugs (ARVs). The government of the republic of Zambia has committed to a programme for the delivery of antiretroviral drugs to the whole population. However as ARV s become increasingly accessible, no clear system of
Microbicidal activity of polyoxidonium in HIV infection prophylactics with discordant partners.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10123); Siziakina L, Kuzina T, Andreeva I, Sokolova J, Kharitonova M, Chumacova E;;;; Medical University , Rostov-on-Don, Russian Federation; Polyoxidonium is a high-molecular physiologically active polymer with evident immunotropic action producing powerful stimulating influence over the phagocytic system cells-monocytes and neutrophils - thus leading to an increase of cytokine synthesis and to phagocytosis as well as cytotoxic activity of NK-ce
Technology transfer for local production of HIV/AIDS-related drugs in Democratic Republic of Congo: a private entrepreneur with social missions.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10128); Kraisintu K, Krabbe A, Eksaengsri A;;;; MFN International Limited, London, United Kingdom; Today, six million people with HIV/AIDS are in urgent need of antiretroviral (ARV) treatment in the developing world, 4.1 million of whom live in sub-Saharan Africa. An estimated 6,000 people die of AIDS each day in this region. Although there is no cure for HIV infection, ARV drugs can dramatically reduce HIV-
Availability and palatability of antiretroviral formulations appropriate for paediatric patients in Thailand.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10133); Kraisintu K, Eksaengsri A;;;; Government Pharmaceutical Organization, Bangkok, Thailand; Thailand , an estimated 700,000 people are living with HIV/AIDS. Approximately 20,000 children aged 15 and less requiring ART. The treatment regimen for paediatric patients should mirror those of adults at all level care. This is currently difficult because of the lack of appropriate paediatric formulations. Cl
Comparision of fine needle aspiration and excision biopsies in the etiological diagnosis of lymphadenopathy in HIV infected patients who attend Mbarara hospital.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10139); Mayanja B, Mpagi F, Katabila E;;;; University, Mbarara, Uganda; The use of Fine needle aspiration biopsy rather than excision biopsy in diagnosing the cause of lymphadenopathy in HIV/AIDS patients should be adopted in a resource limited hospitals. Fine needle aspiration is quick, cheaper, easier, and less harmful to the patient. Methods: The study was done in a Ugandan,
Counseling in Management of HIV among PLWHA in Lagos, Nigeria.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10144); Owolade OE;;;; Aids Alliance in Nigeria, Lagos, Nigeria; With the advertised and publicised government subsidised antiretroviral therapy for ten thousand (10,000) Nigerians, more people now seek testing without clinical symptoms to which a considerable number of people tested positive. The problem is now on how to cope with the knowledge and the psycho- social issues
Linked networks of service: step-by-step development of a technology based adherence program.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10148); Miller A, Gray P, Johnson A, Glass S, Waltrip K, Findley M, Holmes K;;;; Community Based Organization, Chicago, United States; Non-adherence to referrals and treatment plans for clients at high-risk for HIV, sexually transmitted diseases and TB is a problem for human service agencies working in medically underserved, low-income Chicago communities. An electronic, linked network of services (LNS) is needed to address this issue. Descrip
AIDS patients with amebiasis abscesses of liver.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10153); Gordeiko VA, Vashchuk V;;;; Brest state university, Brest, Belarus; Amebiasis abscesses of liver normally are caused by Entamoeba histolitica and found in warm climates. Spreading of AIDS leads to emerging of new patients who exhibit both somatic pathology of liver and HIV-infection. Affection of the digestive system by the opportunistic infection is the main reason of mort
To study efficacy of DOTS in TB patients with HIV coinfection.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10158); Bajaj L, Saini A, Dubey G, Ranjan R;;;; Institution, Bellary, Karnataka, India; HIV inection has emerged as the most important predisposing factor for developing overt TB in people co-infected with M. tuberculosis . Many of these patients seek help in TB sanatoriums. Although anti retro-viral therapy (ART) is not available to most of them but DOTS is freely available in
Study of long term metabolic and morphological side effects of antiretroviral therapy in HIV-1 infected Indian patients.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10163); Patel KK, Patel AK, Patel JK, Shah VN, Mehta NN;;;; ID clinic, Ahmedabad, India; Antiretroviral therapy (ART) is associated with unacceptable long-term metabolic side effects. Methods: Study design: Observational cross sectional study. HIV-1 infected patients completed more than 6 months on ART were looked for metabolic and morphological changes. All patients were followed clinically an
The trials and tribulations of "clinical success" in HIV: exploring new issues and challenges.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10168); Alfonso V, Geller J, Montaner JS;;;; Canadian HIV Trials Network/University of British Columbia, Vancouver, Canada; Accomplishing the goal of antiretroviral therapy, to achieve and maintain an undetectable viral load in plasma, is challenging given that drug regimens require near perfect adherence in order to be effective. To date, most research efforts in the area of adherence have examined adherence problems, and atten
Management of HIV - 1 infection with multi various ART treatment - A medical study about a clinical care centre.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10173); Rajasekaran VN;;;; Meenakshi Mission Hospital and Research centre, Madurai, India; To evaluate the treatment outcome amongst HIV 1 positive patients with a combination of ART drugs under the protocol given by CDC, Atlanta. Design: The study population comprised of 150 patients admitted in the AIDS clinic run by MMHRC. Prior to treatment, the clinical history, personal particulars. 10 ml of
Cryptococcal meningo-encephalitis (CME) in HIV-infected patients - still high mortality despite treatment.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10178); Kowalska J, Podlasin RB, Latarska D, Gizinska J;;;; Hospital of Infectious Diseases , Warsaw, Poland; Cryptococcosis is the most frequent, life-threatening meningitis in AIDS. It s frequency declined less then other s opportunistic infections after introducing HAART. The mortality and morbidity rates are still high despite treatment. Methods: Medical records of 413 HIV-infected patients (pts) hospitalized b
Seroepidemiology of HCV-HIV co-infection in Syria.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10182); Adwan ZS;;;; Damascus, Swaida, Syrian Arab Republic; Introduction: Hepatitis C virus (HCV), recognized since 1989, is a major health problem worldwide. Infection with hepatitis C virus is one of the most common causes of chronic liver disease. Syria is a developing country with low prevalence of human immunodeficiency virus
Evaluation of therapeutic adhesion in patients with HIV positive.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10187); Sow PG, Gueye PM, Diouf M, N'diaye M, Traore I;;;; Institut d'hygiene Sociale (polyclinique), Dakar, Senegal; The cause of ARV treatment failure in HIV infection is multifactorial and may involve poor adhesion, low drug levels,resistant HIV strainsand others demographic or clinical factors. This study is to determine levels of adherence and variables affecting adherence among patients enrolled in our cohort. Method
Incidence of dyslipidemia among HIV patients with or without HAART therapy.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10197); Lai KK, Manchester G;;;; University of Massachusetts Medical School, Worcester, United States; To compare the incidence of dyslipidemia in HIV-infected patients (pts) on highly active anti-retroviral therapy (HAART) with or without protease inhibitors (PIs) and pts on no therapy. Methods: Demographic and laboratory data of HIV/AIDS pts were retrieved from an electronic database of HIV clinic at UMass
How can MTCT-Plus program improve existing HIV care in the hospital?: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10202); Phanuphak N, Chotnopparatpattara P, Chaithongwongwatana S, Santarattiwong P, Kriengsinyot R, U-prasitwong J, Sirisakyot W, Teeratakulpisarn S, Thisyakorn U, Thaithammayanont P, Limpongsanurak S, Phanuphak P;;;; Thai Red Cross AIDS Research Centre, Bangkok, Thailand; MTCT-Plus program introduces practical model of family-centered, multidisciplinary care for HIV-infected patients. While most university hospitals have existing HIV clinics, this model of care may still benefit them by formally organizing the already available services in the hospitals. Chulalongko
CYTOMEGALOVIRUS (CMV) ENCEPHALITIS IN A PATIENT WITH ADVANCED HIV AFTER INITIATION OF HIGHLY ACTIVE ANTIRETROVIRAL THERAPY (HAART): Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10207); Tantisiriwat W, Ruangkit C, Reepolmaha S, Lausoontornsiri W, Harinasuta J, Laohathai P; Encephalitis from CMV was observed 3 weeks after the initiation of HAART in a patient with advanced AIDS and CMV retinitis suggesting an exaggerated pathologic inflammatory response played a role in the pathogenesis of this presentation. Clinicians should be aware of this potential manifestation of CMV IRS and consider systemic therapy of CMV retinitis in persons with advanced HIV infection if HAART is going to be initiated.
Gynecomastia emerging during antiretroviral therapy. What correlations have been explored?: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10212); Manfredi R, Calza L, Chiodo F;;;; Infectious Diseases, University of Bologna, Bologna, Italy; Gynecomastia (G) is an emerging HAART adverse event. Methods: A cross-sectional survey of ~1000 HIV-infected patients (p) was aimed to identify all cases of G related to >1 year of HAART,and to investigate correlation with demographic-epidemiological variables,clinical-laboratory markers of HIV disease,prio
Prevalence of HIV Infection and Concomitant Tuberculosis in A Group of Drug Abusers in the Rehabilitation Camp of Shiraz, South Iran.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10217); Mirahmadizadeh AR, Ghane Shirazi R, Kadivar MR, Hemmati AR;;;; Shiraz university of medical sciencse, Shiraz, Islamic Republic of Iran; Introduction: HIV infection, transmitted mainly through parenteral and sexual routes, has become one of the major health problems in Asian countries. Drug abusers comprise a major high-risk group in the general population. Methods: To study the prevalence of HIV infection among drug abusers, 1061 drug addicts residing
Causes of admission and death as ARV use increases at joint clinical research center-comparision of four periods.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10222); Mulindwa MN, Bateganya M, Kityo C, Ssali F, Mugyenyi P;;;; Joint Clinical Research Center, Kampala, Uganda; The Joint clinical Research Center has pioneered the use of Antiretroviral drugs in Uganda as well as offering comprehensive care to patients with HIV/AIDS. To date, over 12,000 have received ARVs at the center. This is just one percent of all the patients in Uganda who need ARVs. As such management of oppo
An open label study to determine the efficacy and safety of enfuvirtide in patients changing therapy to an NRTI-sparing regimen (ML16992).: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10228); Cooper DA, Dwyer DE, Workman C, Amin C, Miller J, Hales G, Emery S;;;; Westmead Hospital, Sydney, Australia; NRTI adverse effects may restrict their long term use in HIV-1 therapy. The fusion inhibitor enfuvirtide may be useful in NRTI-sparing treatment regimens, although prospective data on the safety and efficacy of such regimens are limited. Methods: 59 HIV-1 infected, triple treatment class (NRTI, NNRTI, PI) e
Efficacy and safety of Zidovudine and Zalcitabine combined with combination of herbs in the treatment of HIV-infected Thai patients.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10233); Sangkitporn DR, Shide DR, Klinbuayaem DR, Leenasirimakul DR, Wirayutwatthana DR, Leechanachai DR, Dettrairat MR, Kunachiwa DR, Thamlikitkul DR;;;; Department of medical sciences, Nonthaburi, Thailand; One of the herbal candidates in the joint research and development between Department of Medical Sciences, Thailand and Kunming Institute of Botany, China is a herbal formulation containing 5 herbs (SH) which has been widely used in China. It was found that each herb and combined SH herbs had anti-retrovira
Characteristics and initial virologic and Immunologic data from the CLARE (CORE Center Lopinavir/r Anti-retroviral Effectiveness)Cohort.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10238); Sherer R, Adeyemi OM, Simeone E, Despotes J, Tschampa J;;;; CORE Center, Cook County Hospital, Chicago, United States; To describe the efficacy, durability and tolerability of Lopinavir/r (LPV/r) based HAART regimens in an urban clinic population. Methods: A retrospective-prospective observational study. Between Oct 2002 and Oct 2003, HIV+ patients currently receiving LPV/r were enrolled in this study. Baseline information
A four-year surveillance study of hospitalization needs of HIV/AIDS patients at an Infectious Disease (ID) reference centre.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10243); Manfredi R, Calza L, Chiodo F;;;; Infectious Diseases, University of Bologna, Bologna, Italy; Notwithstanding the HAART-related change of natural history of HIV,the hospitalization potential of ID wards remains inadequate,according to the continue modification of epidemiology and disease spectrum. Methods: A surveillance study of patients (p) needing hospitalization at our ward and their outcome,was
Toxoplasmosis in HIV/AIDS patients: a current situation.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10247); Nissapatorn V, Lee CK, Quek KF, Leong CL, Rohela M, Khairul Anuar A;;;; Department of Parasitology, University of Malaya Medical Centre, 50603 Kuala Lumpur, Malaysia; To determine the seroprevalence of toxoplasmosis among HIV/AIDS patients, and to determine the frequency distribution and the course of toxoplasmic encephalitis among AIDS patients. Methods: We retrospectively reviewed 505 HIV/AIDS patients who attended in the Hospital Kuala Lumpur from the period of Januar
Tuberculosis in HIV/AIDS patients: a Malaysian experience.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10252); Nissapatorn V, Kuppusamy I, Rohela M, Khairul Anuar A;;;; Department of Parasitology, University of Malaya Medical Centre, 50603 Kuala Lumpur, Malaysia; To compare the characteristics of HIV-positive patients with pulmonary or extrapulmonary tuberculosis , and to describe the organ involvement, diagnosis and their treatment. Methods: This retrospective study was conducted at the National Tuberculosis Centre (NTBC) where 252 HIV-positive patients coexisting
Estimation of clinical events in the control arm of the ESPRIT trial based on data from an observational database.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10257); Lundgren JD;;;; Copenhagen HIV Programme, Copenhagen, Denmark; The efficacy of interleukin-2 boost of the CD4 count is currently tested in controlled trials designed to show improved clinical outcome - the ESPRIT and SILCAAT trials. Observational studies provide a valuable source for estimating clinical event rates for controlled trials, although issues to consider in
Training multidisciplinary teams to assess and support adherence: The Columbia University MTCT-Plus Experience.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10262); Rabkin M, Abrams EJ, El-Sadr W;;;; Columbia University, New York, United States; The Columbia University MTCT-Plus Initiative provides HIV/AIDS care and treatment to women and families in resource-poor settings. More than 400 multidisciplinary team members in 8 countries have been trained to provide family-focused HIV/AIDS primary care, OI prophylaxis, and ART to adults and children. Adhere
Efficacy of T-20 (Enfuvirtide) in a patient recovered from nucleoside-induced lactic acidosis with virological failure.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10268); Harry TC, Stuart H, Wright M, Williams M, Brett B;;;; Bure Clinic,James Paget Healthcare NHS Trust, Great Yarmouth, United Kingdom; A 26 years old white female was diagnosed HIV-1 in October 1995. Baseline CD4 count was 50 cells/ mu l. She started AZT , DDI in November 1995. Treatment was modified due to drug reactions from 1996 - 2001. After Virco VirtualPhenotype ® she started D4T, DDI &
Pharmacokinetics of standard and lower dose indinavir administered with ritonavir 100mg in Asian HIV-infected patients.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10273); Lee LS, Panchalingam A, Yap MC, Paton NI;;;; Tan Tock Seng Hospital, Singapore, Singapore; When co-administered with ritonavir 100mg, lower doses of indinavir than the conventional 800mg may provide equally effective but less toxic drug levels in Asian HIV-infected patients. Methods: Pharmacokinetic parameters were measured in patients who red
The effectiveness of home based care for PLWA in rural Uganda.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10278); Kalyesubula R, Bekunda R, Kibaalya W, Namubiru D, Haag A, Camilo M, Foex JM;;;; Associatio Francois Xavier Bagnaud, Kampala, Uganda; Uganda was one of the first countries in sub-Saharan Africa to experience the devastating impact of HIV/AIDS. Although the Ugandan government has taken important steps to control the epidemic, there still exist gaps in access to care and treatment for people living with HIV/AIDS (PLWA) in rural and undeser
Pro-Viral HIV-1 DNA PCR test for HIV Diagnosis in Infants.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10283); Enzama AR, Mugyenyi P, Kityo C;;;; Joint Clinical Research Centre, Kampala, Uganda; Background;The diagnosis of HIV-1 infection in neonates born to sero positive mothers presents two major dilemmas; the presence of maternal antibodies that preclude the use of serological tests, and the difficulty or impossibility of obtaining large volumes of blood for culture. Objectives;To evaluate a reliable method
HIV and adherence.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10288); Rodkjaer LR;;;; Skejby Hospital, Aarhus, Denmark; Successful treatment of hiv with HAART requires that patient maintain nearly perfect adherence to the prescribed regimen. Suboptimal adherence is clearly the most common cause of virologic failure of HAART regimens. The purpose of the study was to explain how patients living with hiv manage their interactin
Value of dermopathology for differential diagnosis in AIDS-related Kaposi's sarcoma (KS).: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10293); Gulotta HC, Troncoso AR, Rodriguez Rios E;;;; Francisco Muniz Hospital, Buenos Aires, Argentina; KS represented the AIDS-defining diagnosis in the early years of the epidemic. It cannot be distinguished with certainly from other vessels tumors, without the use of biopsy. From January 1, 1990, to December 31, 2002, files of 159 adult HIV-infected patients (pts) derived for KS, based on clinical criteria
HIV-related tuberculosis: how well are we doing with current control efforts?: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10298); Maher D, Borgdorff MW, Boerma JT;;;; World Health Organization, Geneva, Switzerland; HIV is fuelling the tuberculosis (TB) epidemic and TB is a leading cause of illness and death among people living with HIV/AIDS (PLWHA). Interventions to control HIV-related TB comprise measures against both TB and HIV. How well are we doing in high HIV prevalence countries in implementing the interventions
Soudamini : a vision of empowerment for HIV positive network of women with children.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10303); Marne U;;;; Soudamini Network, Mumbai, India; Scares about the spread of HIV coupled with interventions targeted at people who may be seen as reservoirs of infection can lead to stigmatization of people living with HIV and may further marginalize vulnerable communities like women with children which account to almost half the HIV infected population. HIV diagnosis
Profile of children at the paediatric infectious disease clinic,Mulago hospital.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10308); Kekitiinwa AR, Kalyesubura I, Bakeera SK, Namale A, Musoke P;;;; Mulago hospital, Kampala, Uganda; The Paediatric Infectious Disease Clinic is a specialized AIDS clinic established in 1985. Currently, it serves 1200 active clients providing primary care, prevention and treatment of opportunistic infections, counseling and nutritional support. Less than 10% of the children receive antiretroviral therapy.
Compartive study of Epidemiological & clinical manifestations of non opportunistic viral STIs in HIV positive and HIV negative patients.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10317); Mandali AB;;;; Andhra Medical College, King George Hosptial, Visakhapatnam, India; As there is a change in the pattern of the Epidemiology and the clinical manifestations of viral STIs in the presence of HIV infection, a comparative study of non opportunistic viral STIs among HIV Positive and HIV negative patients of North Coastal Andhra Paradesh of India
Virological response and resistance to Lopinavir/Ritonavir in non-B HIV-I patients.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10322); Grossman Z, Lorber M, Shahar E, Torten D, Levi I, Risenberg K, Chowers M, Istomin V, Averbuch D, Burke M, Engelhard D, Sthoeger Z, Pollack S, Kra-Oz Z, Ram D, Rudich H, Mileguir F, Mendelson E, Maayan S, Schapiro JM;;;; National HIV Reference Lab, PHL, MOH, Tel Hashomer, Israel; An algorithm based on the number of specific subtype-B protease gene mutations is commonly used to interpret resistance assay results and predict the response to LPN/RTN. Subtle differences present in the protease gene of non-subtype B patients might influence resistance to LPN/RTN. We compared virological
Access to treatment: importance of Home based care in public health.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10327); Touhon MT, Koffi AC;;;; Centre Plus de Ruban Rouge Cote d'Ivoire, Abidjan, Cote d'Ivoire; Created in 1997 and recognized PLHA centre opportunistic infections follow up by UNAIDS , the Centre Plus (CP) is a daily hospital which ensures free medical and psychosocial support to over 500 PLHA. Anxious the become of patients lost of sight and being in a bad health, the CP initiated from January 2002 to Se
Place of community pharmacy in improvement of observance of PLHA: case of community pharmacy of Ruban Rouge Cote d'Ivoire.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10332); Touhon MT;;;; Centre Plus de Ruban Rouge Cote d'Ivoire, Abidjan, Cote d'Ivoire; To make it possible for PLHA to have access to the treatment, Ruban Rouge CI created the Center More in order to ensure a continuum of care of accessible and free quality. The CP has a Community pharmacy which delivers drugs free to the patients after medical consultation. Since November 2002, pharmacy is manage
Innovative method to sensitize the staff of hospitals to take care of People Living With HIV/AIDS (PLWH/A) in the city of Mumbai India.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10338); Vaswani DV, Gogate AS;;;; Mumbai Districts AIDS Control Society, Mumbai, India; The of shunning away of PLWH/A by the staff of the hospitals was not an uncommon phenomenon in the city of Mumbai. To overcome this various training programes for all the categories were undertaken which brought a little change in the attitude of the hospital staff. Development of Core Committee and Drop-in
Clinical trial on the feasibility and the imuno-virologic efficacy and safety of Fortovase/Ritonavir regimen in Resource-Limited Settings: Case of Senegal.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10343); Ndiaye I, Sow PS, Gueye NF, Diouf LM, Gueye PM, Bassene E, Kane NC, Diaw A, Mboup S;;;; Hospital, Dakar, Senegal; Determine the feasibility of this treatment. Determine clinical efficacy and safety of this therapy. Methodology: This a prospective open study for 96 weeks, including subjects with HIV1+, over 18 years old at B or C stage with CD4 less 350cells/mm3, ARV therapy naive and who accepted after informent consent
Assessments on occupational HIV transmission risks by nursing staff from Germany, Namibia, Poland and Spain.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10348); Klewer J, Lauschke H, Sekula S, Guillen-Grima F, Aguinaga-Ontoso I, Tracogna U, Kugler J;;;; Public Health, Dresden Medical School, Dresden, Germany; To prevent occupational HIV infections in health professionals, comprehensive knowledge about HIV/AIDS is essential. Due to working close to infected patients, especially nursing staff is endangered. Therefore, the study tried to investigate how nursing staff from countries with different HIV prevalences as
Fatal interruption of a 3TC-containing regimen in a HIV-infected patient.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10353); Clevenbergh P, Sellier P, Mazeron M, Cazals-Hatem D, Evans J, Cervoni J, Badsi E, Bendenoun M, Diemer M, Vincent V, Caulin C, Bergmann J;;;; Internal Medicine Dpt, Lariboisiere Hospital, Paris, France; Introduction: Ten % of HIV-infected individuals are hepatitis B virus (HBV) surface antigen-positive (HBs Ag). First line anti-HIV therapy usually contains lamivudine ( 3TC ), a reverse transcriptase inhibitor with antiviral activity against both HIV and HBV.
Does hyponatremia have a predictive value in the diagnosis of extra-pulmonary tuberculosis in HIV-1 infected patients in Cambodia?: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10358); Lynen LM, Phan S, Suos P, Thai S, Harwell J, Boelaert M;;;; Institute of Tropical Medicine, Antwerp, Belgium; Hyponatremia is frequent in hospitalized HIV patients. This seems particularly true for HIV patients with extra-pulmonary tuberculosis (EPTB). EPTB is difficult to diagnose in resource-poor settings. We studied the predictive value of hyponatremia for the diagnosis of EPTB in a cohort of HIV patients. Metho
Seven habits of highly healthy HIV+ people.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10362); Fallon SJ;;;; Skills4, Inc, Ft Lauderdale, FL 33305, United States; Treatment update conferences typically offer medical providers specific treatment durability data. This workshop is designed to help PLWH to understand the important role that a patient s lifestyle choices make in managing HIV, and also to help physicians, nurses, and case managers improve their ability to expl
Toward a comprehensive and effective care: a collaborative approach to care families and persons living with HIV/AIDS.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10367); Diaz Oropeza IF;;;; Fundacion Mexicana para la luch contra el SIDA, A.C., Mexico City, Mexico; WHO considers that care involves biopsychosocial aspects and some authors describe this like a comprehensive approach to care of PWA. The complex nature of HIV/AIDS care is the best argument for enhancing collaboration between health providers, mental health professionals and families living with HIV/AIDS. Desc
A study of nursing care for AIDS patients with Cryptococcal Mengtitis in BI.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10372); Inthong Y;;;; Bamrasnaradura, Nonthaburi, Thailand; This is a descriptive study to explore nursing care provied to AIDS patients with Cryptococcal menigitis based on their health problems and needs and to examine the correlation between patients taught by nurses and the three factors,patients recovery,re-admission and follow-up rate. The sample consisted of 462 AIDS pat
HIV/AIDS: An evaluative study among health care providers of major hospitals of New Dehli, India.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10377); Rasania SK, Singh RN;;;; Department of Community Medicine V.M. Medical College and Safdarjang Hospital , New Dehli, India; HIV/AIDS is among the top killer disease, worldwide. Health Care Providers (HCPs) have to protect themselves from HIV/AIDS. They have to provide, to unfortunate persons suffering from HIV/AIDS; care and full emotional support. This depends on their knowledge about this subject. But are they willing to provi
Highly active antiretroviral therapy (HAART) in HIV- infected Africans: The question of optimal time to start.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10382); Erhabor O, Ejele OA, Nwauche CA;;;; Department of Haematology and Immunology University of Port Harcourt PMB 1 Choba , Port Harcourt, Nigeria; Highly active antiretroviral therapy (HAART) has changed the landscape of HIV related care in the developed world but its benefits have not been well elucidated especially among Africans. In this study, we have compared the immunological response to HAART in Africans based on starting baseline CD4 count. Me
Women involvement in support goup activities in Zambia.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10387); Kunda WV;;;; Kabwe DHMT, Kabwe, Zambia; There has been more women involvement in support group activities, primarily because of their significant role as care givers and as pillars at both family and community levels. Those with the expectation that the same service would be provided to them in time of need. The support groups surveyed relied exclusi
Efficacy to hepatitis B vaccination and its relationship with T CD45RA+ (naive) and CD45RO+ (memory) subsets in HIV-1-infected subjects.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10392); Casseb J, Veiga AP, Duarte AJ;;;; FMUSP, Sao Paulo, Brazil; After successful HAART, there are increased numbers of T CD4+ memory and naive cells, and there is an improvement of antibody response to new antigens. We studied the efficacy of vaccination against HBV in HIV-1-infected subjects on HAART and analyzed the factors involved in the failure. Methods: 55 HIV-1-i
Clinical effectiveness of HCV treatment in HIV/HCV co-infected patients and the utility of liver biopsy in real practice.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10397); Chihrin S, Loutfy MR, Raboud J, Saskin R, Govan V, Dimayuga R, Rachlis A, Kovacs C, Crouzat F, Tilley D, Chang B, Phillips E, Walmsley S, Fletcher D;;;; Canadian Immunodeficiency Research Collaborative, Toronto, Ontario, Canada; To determine the utilization of liver biopsy and effectiveness of interferon (IFN) (regular and pegylated) plus ribavirin (RBV) in HIV/HCV co-infected patients. Methods: A retrospective chart review was completed for 151 HIV/HCV co-infected patients from 2 Toronto centres. Reasons for and treatment decision
Acupuncture trial in side-effect management and adherence enhancement.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10402); Sommers EA, Porter KE;;;; AIDS Care Project, Boston, United States; Acupuncture has demonstrated efficacy in managing digestive side-effects of medications used in cancer chemotherapy and following anaesthesia. This clinical trial examines the role of acupuncture in controlling side-effects related to the use of highly active antiretroviral therapy (HAART). HAART therapy re
Antifungal interventions for the primary prevention of cryptococcal disease in persons with HIV: a systematic review.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10408); Chang LW, Phipps WP, Kennedy GE, Rutherford GW;;;; University of California, San Francisco, San Francisco, United States; Cryptococcal disease is a major source of morbidity and mortality in persons with HIV, particularly in the developing world. In this systematic review, the efficacy of antifungals for the primary prevention of cryptococcal disease in persons with HIV will be assessed. Methods: We searched for randomised con
HIV-associated lipodystrophy in Thailand: The prevalence clinical characteristic and metabolic consequence.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10413); Puttawong S, Prasithsirikul W, Vadcharavivad S;;;; Bamrasnaradura Infectious Disease Institute, Nonthaburi, Thailand; HIV-associated lipodystrophy syndrome(LD) is a recently recognized syndrome characterized by morphologic and metabolic changes observed during antiretroviral therapy(ART). The morphologic change can be highly stigmatizing and the metabolic manifestation may contribute to a range of morbidities. The objectiv
AIDS-wasting syndrome in women patients.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10417); Gulotta HC, Espinosa G, Levi N, Cacciavillani M, Cazalla L, Rossi ML, Monteagudo M, Troncoso AR;;;; Infectious Diseases Francisco J Muniz, Buenos Aires, Argentina; Malnutrition is common among individuals suffering advanced HIV disease. The purpose of this work was to assess the impact of HIV infection on nutritional status. Methods: Prospective single-center observational study of 124 pts. Anthropometric parameters (weight, size, and arm muscle circumference, tricipi
Pharmacokinetics of indinavir in Koreans compared with Caucasians.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10422); Choi JY, Chang KH, Park YS, Cho CH, Shin SY, Han SH, Choi SH, Chin BS, Park YS, Song YG, Kim JM;;;; AIDS Research Institute, Yonsei University College of Medicine, Seoul, Republic of Korea; Metabolic complications of indinavir, such as lipodystrophy or hyperlipidemia, are rare in Koreans. We evaluated whether the pharmacokinetic parameters of indinavir in Koreans and Caucasians differ. Materials and Methods: Indinavir 800 mg was administered orally to eight healthy male Koreans and four health
Profile of tuberculosis (TB) with HIV-AIDS in 350 patients at community care center, Mumbai.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10428); Golhar DA, Bora PC, Vasvani D, Gogate A;;;; Community Care Centre,Sarvodaya Hospital, Mumbai, India; Tuberculosis is the commonest opportunistic infection seen in patients living with HIV AIDS. The dual epidemic of HIV and Tuberculosis is on the rise. Clinically active Tuberculosis develops in a stage where cell mediated immunity has just started to deteriorate which is reflected by low CD4 count of 200 - 500 /dl. Met
Day care for children living with AIDS in resource limited settings.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10432); Sims R, Eriki M, Awori M;;;; Jajja's Home Mildmay International, Kampala, Uganda; Issue : Care for children living with AIDS is not a priority in many resource limited settings, resulting in children dying prematurely, unnecessarily and in distress. Rehabilitation, in the form of holistic palliative care, can restore the health of many children to a point where they can benefit from anti-retroviral
Predicting the CD4 count from the result of dinitrochlorobenzen skin test using linear regression analysis.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10437); Nguyen NL;;;; Faculty of Medicine, Hue, Vietnam; Background:The CD4 count is being used to evaluate the immune status of HIV- infected person, but it is too expensive to become popular in developing countries. The DNCB (Dinitrochlorobenzen) skin test has been used by immunologist to evaluate the cell-mediated immune response. Some investigators proposed some blood pa
Mother-to-child transmission of hepatitis C virus in babies born to co-infected both HIV and HCV women.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10442); Zverev SY, Alikina YI, Novikova OV, Zemskova EA;;;; Regional AIDS Centre, Perm, Russian Federation; Of 4,915 HIV-infected persons registered on the 1-st of January, 2004, in Perm region, 29,5% were women of fertile age and co-infected with HIV-1 and HCV. To evaluate risk of HCV maternal transmission to babies exposed to both viruses we have investigated all cases of childbirth among these women. Methods:
Control of HIV/AIDS in a migrant dominant city: An experience of Surat city in western India.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10452); Rathod UL;;;; Institution, Surat, India; Controlling STDs and HIV/AIDS in a city of 2.5 million inhabitants through counseling, complete treatment, contact treatment and condom promotion within the existing health apparatus. Instead of a target group focused approach adoption of an overarching umbrella approach covering various occupational and social
Prolonged survival of end-stage AIDS patients receiving V-1 Immunitor.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10457); Metadilogkul O, Jirathitikal V, Bourinbaiar AS;;;; 1Occupational and Environmental Medicine Association of Thailand, Rajavithi General Hospital, Bangkok , Thailand; As there is still neither a cure for the acquired immunodeficiency syndrome (AIDS) nor a vaccine to prevent human immunodeficiency virus (HIV) infection, an AIDS diagnosis remains associated with death sentence. Thailand is one of South-East Asian countries with high prevalence of HIV infection, where most
Comparison of the Abbott HIV Ag/Ab Combo and the HIV1/2 Axsym gO assays.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10462); Janse van Rensburg E, Lotter S, Wilsdorf L, Robson B, Canosci A;;;; University of Stellenbosch and National Health Laboratory Service , Tygerberg, South Africa; Comparison of the performance of the Abbott HIV Ag/Ab Combo (Combo) assay that detects both HIV antibodies and p24 antigen to the Abbott Axsym HIV 1/2 gO (gO) assay that only detects HIV antibodies, in a public hospital setting in Cape Town, South Africa . Methods: The following samples were tested: 300 rou
Field Evaluation of Rapid Antibody Test for Detecting an Confirming HIV Infection in Guatemala. Fase I and II.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10467); Arana FE, Hernandez DB, Aguilar JS, Campoyo E, Branson B, Mejia C, Arathoon E, Samayoa B;;;; Universidad del Valle de Guatemala, Guatemala, Guatemala; Recent advances in the areas of rapid test for HIV have resulted in the availability of new, simple rapid tests that are suitable for use in settings with limited technical resources. OBJETIVES: Evaluate the feasibility and reliability of a strategy using two or three rapid tests for confirmation of test re
The provision of nevirapine for the prevention of mother-to-child transmission of human immunodeficiency virus in Puerto Plata, Dominican Republic.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10473); Galpin LE, Tebas P, Gomez B;;;; Washington University in St. Louis, St. Louis, United States; The adult prevalence rate of HIV infection in Puerto Plata was estimated to be 4.5% in 1999, significantly higher than the national prevalence rate of 2.8%. Among antenatal women in Santo Domingo, the capital city, UNAIDS /WHO estimated the HIV prevalence rate to be between 1 and 2% between 1991 and 1998. I
Dual TB/HIV epidemic in the northern Thailand and Myanmar border: The vital need for bridging cross-country cooperation.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10478); Wandee P, Supawitkul S, Pinta N, Ngoentong Y, Khunkonkapan S, Kaewkampa P, Sumanapun S, Levine W, Sinsomboontong S, Mednavyn T;;;; Chiang Rai Provincial Health Office, Chiang Rai, Thailand; Dual TB and HIV/AIDS epidemic is common especially in developing countries. Inter-country cooperation is still less addressed. Method: We reviewed TB/HIV patient data in a Thailand community hospital. The hospital provided TB and HIV care for patients living in the border area of Thailand and
Measurement error affects choice of endpoint definition, misclassification and sample size in a survival study.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10483); Wong H, Yu E;;;; Canadian HIV Trials Network, Vancouver, Canada; The time taken for the CD4 cell count to fall below a threshold value is often used as the endpoint in a clinical trial. Deciding whether endpoint has been met based on a single CD4 determination may be inaccurate since the true CD4 count is subject to natural physiologic variation and assay error. Hence in
A community response to the challenges of expanding ARV treatment for PLW HIV/AIDS.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10488); Ilboudo M, Koala DR, Traore M, N'guyen Vinh-kim DR;;;; Association African Solidarite, Ouagadougou, Burkina Faso; Introduction: Projet Orange, fruit of the partnership between Association African Solidarite (AAS) and Alliance Internationale is aimed at developing a strong community based center to expand access to HIV/AIDS treatments in Burkina Faso . It will serve model for the safe and effective use of ARV s. Strategy: The strat
Partial virologic suppression associated with antiretroviral prophylaxis for materno-fetal transmission (MFT) and efficacy of future treatment.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10493); Khuong-Josses MA, Chaplain C, Khelil N, Mechali D;;;; Delafontaine Hospital, Saint-Denis, France; Antiretroviral therapy (ART) has contributed to the dramatic decline in MFT of HIV in developing countries. However, zidovudine (ZDV) alone does not fully suppress HIV replication, and chemoprophylaxis with ZDV alone might select for ZDV-resistant viral variants, affecting future response to ZDV-containing regimens. Me
HIV and pregnancy. Fertility help to HIV discordent couples. Experiences from Skejby Hospital, Denmark.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10499); Laursen T, Hoegaard A, Ingerslev HJ, Oestergaard L, Kesmodel U;;;; Skejby University Hospital, AArhus, Denmark; In 2002 a concensus was made in Denmark to help HIV discordent couples. Up till 2002 patients were advised not to have children, because of the risk of transmitting the virus to the partner and child, and because of ethical reasons. The antiretroviral treatment has changed this, HIV is now considered a chro
Malnutrition in HIV infected Cambodian children.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10504); Seitaboth S, Brady MF, Lurie M, Akao K, Hendricks K, Pugatch D;;;; Angkor Hospital for Children, Siem Reap, Cambodia; Both malnutrition and HIV are prevalent in Cambodia . To date, the relationship between malnutrition and HIV disease stage has not been well described in Cambodian children, but malnutrition is likely to impact on the course of HIV infection. We examined the relationship between malnutrition, assessed by an
Seroprevalence Pattern of Spouses attending Prenatal Clinical Laboratory in LUTH, Lagos - Nigeria.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10509); Badaru SO, Omilabu SA, Ajayi GO;;;; Virology Research Laboratory, Department of Medical Microbiology and Parasitology, College of Medicine, University of Lagos,, Lagos, Nigeria; Vertical transmission of HIV could be minimized or even prevented if adequate preliminary tests including screening and confirmatory tests for HIV-1 & 2 were carried out for spouses (or intending parents) before admission to the antenatal clinic. The preliminary tests would facilitates monitoring and ma
HIV risk behavior in Methamphetamine dependent population.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10514); Elkashef A, Smith EV, Rawson R, Pearce VJ, Ling W, Vocci FJ, Campbell J, Haning W, Mawhinney J, McCann MJ, Weis D, Johnson B;;;; DHHS/NIH/NIDA, Bethesda, MD, United States; Increased HIV risk behavior has been linked to Methamphetamine dependence among the homosexual population, and has been assessed throughout the clinical studies recently conducted by NIDA, and the Methamphetamine Clinical Trials Group (MCTG). One of the outcomes of these studies is to determine if treatment
Long-term intake of Korean red ginseng causes deletion in the nef gene as well as slow progression.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10519); Cho Y, Lee H, Yang H, Ahn S, Lee H;;;; Asan medical center, University of Ulsan, SEOUL, Republic of Korea; Despite the introduction of HAART in AIDS therapy, HIV-1 infection is still not curable. A variety of immune-based therapies are under consideration to improve immunological functions in HIV-1-infected patients. Ginseng is recorded as the best medicine of all in Shen Nung s Pharmacopoeia compiled between A.
Increased body weight and improved quality of life in AIDS patients following V-1 Immunitor administration.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10524); Bourinbaiar AS, Jirathitikal V, Metadilogkul O;;;; Immunitor Corp., Co., Ltd., Takarm, Thailand; Development of affordable and safe therapy to reverse the loss of body mass is of critical importance since AIDS-related wasting is associated with increased mortality. We have demonstrated earlier that oral therapeutic HIV vaccine, V-1 Immunitor (V1), tested in a small group of AIDS patients in
Accompaniment program with psychologist's students for PLWA with ARV adherence problems that attend the external consultation of infectologist, in the Dr. Calderon Guardia Hospital. San Jose, Costa Rica.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10529); Gutierrez R;;;; Hospital Dr. R.A. Calderon Guardia, San Jose, Costa Rica; General To offer accompaniment (support) to PLWA who take ARV treatment and present adherence problems. Specific Objectives: 1. To accompany to the PLWA in their emotional necessities. 2. To offer counsel and education in HIV/AIDS for PLWA, to improve the ARV adherence. 3. To modify the behaviors that avoids
The use of atypical antipsychotic medication for the adjunctive treatment of AIDS patients with substance abuse and psychiatric symptoms.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10533); Bialos DS, Cederblom L, Selwyn P, Rivard M, Constantino J;;;; Leeway Skilled Nursing Facility, New Haven, United States; AIDS patients with substance abuse and psychiatric symptoms present treatment difficulties, including poor adherence to complex regimens, impaired judgment and impulse control (J/IC) and maladaptive behavior. Psychiatric comorbidity is a problem in patients with HIV/AIDS who require long term care. We studi
Clinical and immunological responses to triple combination antiretroviral therapy in burundian children.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10538); Kariyo P, Ntwari RC, Baramperanye E, Mbuzenakamwe MJ;;;; Chu de Kamenge, Bujumbura, Burundi; The advent of antiretroviral therapy allowed reducing mortality and morbidity associated with HIV related diseases. The goal of this study is to evaluate the clinical and immunological effectiveness at one-year treatment of a triple combination of ART in naive children. Methods: A cohort of HIV infected nai
Increased survival among AIDS patients in San Francisco who initiated treatment with the "one-size-fits-most" WHO/UNAIDS recommended regimens.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10544); Chen SY, Hsu L, Schwarcz SK, McFarland W;;;; Johns Hopkins Bloomberg School of Public Health, Baltimore, United States; The WHO/ UNAIDS plan to treat three million HIV-infected persons by 2005 recommends four antiretroviral drug combinations. We used AIDS surveillance and mortality data in San Francisco to compare the survival experience of persons who initiated treatment using a WHO/UNAIDS versus non-WHO/UNAIDS regimen. Met
Treatment outcome and expenditure in HIV patients who received triple therapy in Phayao, 2001-2002.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10549); Panpattanakul S;;;; Phayao Provincial Health office, Phayao, Thailand; To study the treatment outcome and expenses of 91 patients from 142 HIV infected patients who received triple therapy after 1 year of treatment during February 2001 - September 2002 in 6 hospitals of Phayao province. Method: Collecting the data from the existing treatment records (ATC 1) and developing quest
Factors associated with liver biopsy performance in HCV-HIV co-infected injecting drug users with HCV viremia: results from a 5-year longitudinal assessment.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10554); Spire B, Carrieri MP, Rey D, Loubiere S, Dujardin P, Mechali D, Cassuto JP, Obadia Y;;;; INSERMU379/ORS, Marseille, France; Background : The need to provide HCV treatment to people co-infected with HIV was addressed in the last international consensus conference about HCV treatment. Until 2002, a liver biopsy was mandatory in France to assess the indication of antiviral therapy for HCV infection. We aimed to identify factors associated with
Characteristics of HIV- infected children< 13 years receiving highly active antiretroviral therapy (HAART) at Lighthouse clinic at Lilongwe Central Hospital (LCH), Lilongwe, Malawi.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10559); Weigel R, Tauzi J, Thambo L, Hosseinipour M, Neuhann F, Boxshall M, Phiri S;;;; The Lighthouse Centre at LCH, Lilongwe, Malawi; Since the availability of affordable generic syrups and tablets (20-30 US$), HAART for children became an option. Here, clinical course and outcome are described in order to contribute information to the scale up process for this age group. Methods: From 09/02 until 12/03, a prospective observational cohort
Sexuality and reproduction among adolescents living with HIV/AIDS (ALWHA) in Sao Paulo, Brazil.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10564); Paiva V, Ayres JR, Della Negra M, Franica I Jr, Galano E, Segurado A, Lecussan P, Silva M, Lacerda R, Gravato N;;;; Psychology - Univ. Sao Paulo, Sao Paulo, Brazil; The number of adolescents living with HIV/AIDS is increasing in Brazil , due to free access to HAART that enhance quality of life of children who were born with HIV & to sexual infection of adolescents living in vulnerable contexts. Sexual and reproductive health care needs and support for psychosocial
Detection of cervicovaginal HIV at enrollment among women in a clinical trial of a vaginal microbicide in Northern Thailand.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10569); McLean CA, Chaowanachan T, Evans-Strickfaden T, van de Wijgert J, Kantipong P, Kilmarx PH, Mock P, Whitehead S, Siraprapasiri T, Hart CE, Tappero JW, Markowitz LE;;;; Division of STD Prevention, Centers for Disease Control and Prevention (CDC), Atlanta, GA, United States; A randomized, controlled, cross-over trial is being conducted to evaluate safety and acceptability of a candidate vaginal microbicide (Carraguard®) among HIV-infected women in Thailand . Eligibility criteria include a CD4 cell count of 50-500 cells/muL and not currently taking antiretroviral therapy. T
Evaluation of HAART treatment effective by HIV-1 quantitative method and immunological function inspection.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10574); Chen L, Feng TJ;;;; Shenzhen Center for Disease Prevention and Control, Shenzhen, China; To observe and evaluate the effectiveness of highly active antiretrovirus therapy (HAART) on HIV/AIDS patients by HIV-1 load and T subsets analysis. Methods: Using HIV-1 quantitative RT-PCR methods and immunological function inspection, we monitored 4 HIV/AIDS patients who were suffering from immunological
Clinical evaluation of HIV-infected women screened for a clinical trial of microbicide safety in Northern Thailand.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10579); McLean CA, Kantipong P, Chaowanachan T, van de Wijgert J, Medtanavyn T, Braunstein S, Whitehead SJ, Siraprapasiri T, Tappero JW;;;; Division of STD Prevention, Centers for Disease Control and Prevention (CDC), Atlanta, GA, United States; We screened HIV-infected women for participation in a safety and acceptability trial of a candidate vaginal microbicide (Carraguard®) in Northern Thailand . Eligibility criteria include abstinence or a HIV-infected husband or steady sex partner, regular menstrual cycles, not currently taking antiretrov
Uptake of interventions, preliminary outcomes and challenges in caring for HIV exposed infants in Kingston, Jamaica. A preliminary report of the Kingston pediatric and perinatal HIV/AIDS program, september 01, 2002 - august 31, 2003. Funded by the Elizabeth Glaser pediatric AIDS foundation, international leadership award 1-ILA-11-01.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10584); Steel-Duncan JC, Pierre R, Evans-Gilbert T, Rodriquez B, Smikle M, Palmer P, Whorms S, Hambleton I, Figueroa P, Christie CD;;;; University of the West Indies, Kingston 6, Jamaica; In a few Caribbean islands, pMTCT of HIV with zidovudine prophylaxis has reduced transmission rates from 27 - 44% to 5.5 - 9%. This paper highlights the uptake of interventions, preliminary outcomes and challenges in caring for HIV exposed infants in a pMTCT program in a resource-limited setting. Methodolog
Reintegrating HIV+ incarcerated individuals into the community: Preliminary outcomes of the Massachusetts transitional intervention project (TIP).: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10588); Logan JA, Barker T, Zafft W;;;; Massachusetts Department of Public Health HIV/AIDS Bureau , Boston, United States; Currently, 7% of the individuals living with HIV/AIDS in Massachusetts, U. S. were diagnosed while in a correctional facility. Statewide, 69% of individuals diagnosed with HIV/AIDS during incarceration were from communities of color compared to 51% of all individuals living with HIV/AIDS. Known HIV+ individuals
Needle syringe a basics need for an IDU in HIV prevention.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10592); Gupta VK;;;; Sharan- society for urban poverty, New Delhi, India; To sensitize the government for the importance for continues N/S exchange program in Delhi It is situated at bank of Yamuna River. Sharan have been working in this area since 1998 with the primarily focus of reaching out to the marginalized population from the lowest stature of life and we have been
Treatment changes and virological suppression in HIV patients treated with HAART.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10596); Schmeisser N, Woehrmann A, Qurishi N, Salzberger B, Rockstroh J, Faetkenheuer G;;;; Department of Internal Medicine, University of Cologne, Germany; Previous studies have shown that treatment changes occur frequently in patients initiating HAART for the first time. We were interested in the relationship between treatment changes and virological outcome of these patients. Methods: Prospective observational study of all patients treated in two outpatient c
Effect of ART on heart function in HIV infected children.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10600); Rosso R, Ferrazin A, Cassottana P, Di Biagio A, Ferrando S, Dentone C, Bassetti M, Chierchia S, Bassetti D;;;; Infectious Diseases Clinic, University of Genoa, S. Martino Hospital, Genoa, Italy; Children born from HIV+ mothers (pts) can develop cardiovascular abnormalities, which may arise from exposure to HIV and/or from ART. We evaluated possible cardiovascular involvement in long-term treated pts. Methods: Quantitative M-mode-2D-Doppler CW-PW-color trans-thoracic echocardiogram (TTE) was perform
Blood transfusions (BT) in the aspect of HIV-prevention: clinical practice.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10604); Sarmanaev SK;;;; Hospital 21, Ufa, Russian Federation; As compared to the transfusional practice of Western countries, in Russia blood products per patient are used several times more. A reason for this lies in existence of prescriptions for use of blood products on a scale which may be considered excessive (Molchanov, 1999). In our region, an increase in numbe
Lung cancer in 61 HIV-infected patients: a pre- and post-HAART era analysis.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10608); Bearz A, Vaccher E, Spazzapan S, Berretta M, Spina M, Tirelli U;;;; National Cancer Institute, Aviano (PN), Italy; Lung cancer, one of the most frequent non-AIDS-defining tumors, showed aggressive clinical course in the pre-HAART era. To assess the influence of HAART on HIV-related lung cancer, we retrospectively analyzed 61 cases collected on behalf of GICAT (Italian Cooperative Group on AIDS and Tumors)Clinical data of HIV-infect
Genotypic HIV-1 drug resistant strains among children receiving antiretroviral therapy in Abidjan, Cote d'Ivoire.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10612); Adje-Toure CA, Fassinou P, Borget MY, Barouan MC, Diomande F, Maurice C, Nolan M, Nkengasong JN;;;; Projet RETROCI, 01 BP1712 ABJ 01, Cote d'Ivoire; To determine the prevalence of HIV-1 antiretroviral genotypic drug-resistant strains among children receiving antiretroviral therapy (ART) for approximately 1 year in Cote d Ivoire . Methods: Between August 1998 and September 2002, 260 HIV-infected children (age, 0-15 years) received ART in Abidjan. We teste
Improvements of lipid profile in a cohort of adolescents with perinatal HIV infection.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10616); Rosso R, Ferrando S, Dentone C, Di Biagio A, Ferrazin A, Beltrame A, Bassetti M, Bassetti D;;;; Infectious Diseases Clinic, University of Genoa, S. Martino Hospital, Genoa, Italy; Protease inhibitors (PIs) have been associated with metabolic complications in children and adolescent HIV positive patients (pts). Replacement of PIs by efavirenz (EFZ) has been attempted to reduce these toxicities. We analyze the efficacy and evolution of lipid profile after replacing PIs by EFZ in pts be
Building trust in male sex workers in Lahore to access qualified doctor instead of quacks for treatment of sexually transmitted infections.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10620); Rafique MA;;;; Vision, Lahore, Pakistan; According to a situational needs assessment commissioned by World Bank and DIFID in Pakistan along with National AIDS Control Program in Pakistan and carried out by Vision Lahore in collaboration with Naz Foundation International in United Kingdom in year 2001, it was discovered that majority of the street
How can MTCT-plus staff and hospital's policy makers contribute to the success of MTCT-plus program in the hospital?: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10624); Luesomboon W, Methajittiphan P, Sirimasakul W;;;; Queen Sawangwattana Memorial Hospital, Chonburi, Thailand; PMTCT program initiated in 1996 led to many orphans after their parents passed away. MTCT-Plus program was set up to provide supports in order to give their parents opportunities to live with their children. Not only medical care, usually only ARV, but also comprehensive care should be provided to them. Every a
Innovative PMTCT programs at PHC level in rural settings: Initital results from Kilombero and Hai districts in Tanzania.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10628); Kironde S, Munisi W, Ntyangiri E, Msaky H, Wilfert C, Masuki G, Mlay V, Saba J;;;; Axios , Kampala, Uganda; In 2002, PMTCT services were only available at 5 tertiary hospitals in Tanzania and only 30% of antenatal attendees where actually getting counseling and HIV testing. In 2003, the district health authorities, with funding from the Elizabeth Glaser Pediatric AIDS Foundation and technical assistance from Axio
Hepatitis B virus infection in patients attending HIV testing and counseling clinics: risk factors and vaccination coverage.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10632); Rodriguez C, Sobrino P, Vall M, Alastrue I, Camara MM, Bru F, Varela JA, Junquera ML, del Romero J, Castilla J; Centro Sanitario Sandoval, Madrid, Spain; Vaccination against Hepatitis B virus (HBV) is specially indicated for individuals presenting parenteral or sexual risks. Vaccination coverage and serological situation have been evaluated for various risk population groups. Methods: Transversal study of first time HIV testers in 8 clinics in
Diagnosis - outline and efficacy of strategies to reduce mother-to-child HIV transmission in service of specialized care (SAE) in University Hospital Lauro Wanderley in Joao Pessoa, Paraiba, Brazil, 1998 - 2003.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10636); Pinho Neto OS, Frade JD, Madruga MF, Diniz MG, Oliveira IC, Chacon N, Medeiros F;;;; University Hospital Lauro Wanderley/Federal University of Paraaba, Joao Pessoa, Brazil; This study evaluated the success of service of specialized care (SAE) of University Hospital Lauro Wanderley has with recommendations of a National Program (PNDST/AIDS-MS) for the prevention of mother-to-child transmission (MTCT) of HIV in 46 mother-infant pairs from Joao Pessoa, Paraiba, Brazil . This population
Use of traditional medicine in the era of antiretroviral therapy: experience from South Africa.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10640); Babb DA, Pemba L, Seatlanyane P, Charalambous S, Churchyard GJ, Grant AD;;;; London School of Hygiene & Tropical Medicine, London, United Kingdom; Traditional medicine is widely used in southern Africa. We investigated the use of traditional medicines among HIV-infected individuals attending a workplace clinic in South Africa where an ART programme has recently been launched. Methods: We interviewed clinic attendees with moderate or advanced HIV disea
Nevirapine related toxicity in a Nigerian patient receiving a fixed dose drug combination pill: considerations in an era of rapidly expanding access to antiretrovirals (ARVs) in resource poor nations.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10644); Krain A, Daniel O, Ogun S, Odusoga O, Falola R, Kolapo K, Boyle B;;;; Weill Medical College of Cornell University, New York, United States; Nevirapine related toxicities, including rash and hepatotoxicity, are well described. To decrease the risk of toxicities a 14 day lead in period and careful monitoring are recommended. Increasing availability of nevirapine in countries with limited provider experience or where only fixed-dose drug combinations
A multidisciplinary approach to HIV care in an urban homeless population in the United States.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10648); Hohl CA;;;; Boston Health Care for the Homeless Program, Boston, United States; In the US, urban homeless individuals have a higher prevalence of substance abuse, mental illness and exposure to violence than the general population, making them at increased risk for HIV and complicating management of the disease. Identifying homeless people infected with HIV is difficult but vital. Treatment
Pegylated interferon and ribavirin for therapy of chronic heptitis C in HIV infected patients.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10652); Sanchez-Montero F, Pascua J, Costo A, Sanchez JF, Sanchez T, Martin C;;;; Hospital San Pedro Alcantara, Caceres, Spain; Chronic hepatitis C is a growing cause of morbi-mortality in HIV infected patients. Therapy of chronic hepatitis C has improved with the introduction of pegylated interferon and ribavirin. Currently, the sustained virologic response is 60% in HIV negative patients. We have evaluated the efficacy and safety
Peer counseling in the primary care setting.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10656); McCaffrey M;;;; Kansas City Free Health Clinic, Kansas City, Missouri 64109, United States; After a client is engaged in care several factors can affect the outcome of treatment. they include adhering to antiretroviral therapy, keeping medical appointments, and communicating problems to providers. Linking patients with trained peer counselors can bridge this chasm to improve overall engagement to care
Clinical and epidemiological analysis of HIV and HBV occupational exposure (OE) in health care workers (HCWs).: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10660); Benetucci J, Oliva SM, Metta H;;;; Hospital de Infecciosas F. J. Muniz - FUNDAI, Buenos Aires, Argentina; To assess the clinical features of OE, the correct use of PEP and the evolution of the HCWs. Methods: Prospective study in 202 HCWs. Demografic characteristics, features of the exposures, rational use of PEP and the evolution of HCWs were studied. Results: From 1998 to 2003, 202 HCWs were reported. Women: 1
Two non-nucleosides association as part of salvage therapy in highly pre-treated patients.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10664); Guelar A, Knobel H, Vallecillo G, Montero M, Gonzalez A, Saballs P, Gimeno JL, Lopez-Colomes JL;;;; Hospital del Mar, Barcelona, Spain; Objective. Limited in vitro data about the use of nevirapine + efavirenz reported controversial results. One clinical trial in naive patients suggests that combination of these drugs obtained poor results than the use of one of them alone, mainly because of adverse
Adverse reactions among HIV-infected patients initiating antiretroviral therapy in Brazil.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10668); Menezes-Padua CA, Bonolo PF, Cesar CC, Guimaraes MD;;;; Universidade Federal de Minas Gerais, Minas Gerais, Brazil; Adverse reactions are frequently reported by HIV-infected patients on antiretroviral therapy (ARV) and they are one of the most common reasons for non-adherence and discontinuation of therapy. However, there is little information in Brazil , where HAART therapy is widely available, on adverse reactions amon
HIV/AIDS management and control in the Uganda Prison Service (UPS).: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10672); Kaddu M, Nabatanzi F;;;; Uganda Prisons Service, Kampala, Uganda; Humane custody as a component of the UPS Mission includes maintenance of an acceptable level of health. The Prisons Health Service is mandated with the control and management of HIV/AIDS. A prisons HIV/AIDS Control Programme (UPACP) was established in 1993 to reduce the spread of HIV/AIDS and addre
12 months of prospective follow-up of haart (highly active antiretroviral therapy) in a hospital-based cohort of HIV-seropositive patients in San Isidro, Buenos Aires, Argentina.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10676); Beltran MA, Nasiff V, Gil RA, Sanga N, Loza S;;;; Hospital San Isidro, San Isidro, Argentina; AIDS and HIV-1-seropositive patients from Argentina have free access to HAART since 1996. We assist patients from 1987 at our Service. Since march 2002 we included all our patients in a prospective follow-up cohort. We describe in this report events related to HAART during 12 months. to describe: 1- baseline
Clinical spectrum of HIV infection in children at a tertiary care center.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10680); Oswal JS, Lalwani SK, Kalrao VR;;;; Bharati Vidyapeeth Medical College, Pune, India; The HIV infection in children is still a major problem in developing countries like India . We studied clinical spectrum of HIV-infection in children at a tertiary care center. Methods: From October 2001 onwards, 45 HIV-infected children were referred to HIV clinic. All the children were thoroughly examined
Growth, developmental and behavioral outcomes of HIV-affected preschool children in Thailand.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10684); Sanmaneechai O, Puthanakit T, Louthrenoo O, Sirisanthana V;;;; chiang mai university, chiang mai, Thailand; Uninfected children born to HIV-seropositive mothers (HIV-affected children) are growing up in a non-nurturing environment. The study is aimed at determining the growth, developmental and behavioral outcomes of Thai HIV-affected preschool children. Methods: A cross-sectional study of 30 HIV-affected childre
Retrospective study regarding the prognoses of children born from HIV-1 infected women in Japan.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10688); Kasai T, Togawa M, Ohba T, Kunikata T, Ozaki Y, Takayama N, Imura S, Kita T, Taniguchi H, Hayashi K, Tsukahara Y, Wada Y, Minoura S, Abe S, Sakumoto K, Takano M, Hasuo Y, Hayakawa S, Kitamura K, Yoshino N, Inaba J, Totani R, Inaba N;;;; Department of Pediatrics, Iwate Medical University, Morioka, Japan; Our study purpose is to clarify and describe mother-to-child transmission (MTCT) of HIV-1 in Japan . Method: Clinical information regarding 193 live births born from HIV-1 positive mothers from 1984 through to 2002 was analyzed retrospectively. Results: MTCT rate was 15.5% (30/193) in total. According to th
Prevalence of Salmonella and Shigella species in HIV/AIDS patients with diarrhoea in Lagos, Nigeria.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10692); Oparaugo CT, Idigbe EO, Onyewuche JI, Adetiloye EB;;;; Nigerian Institute of Medical Research , Yaba, Lagos, Nigeria; This study was carried out between January and December 2002 to determine the prevalence of Salmonella and Shigella species in the stool of HIV positive patients with diarrhoea in Lagos, Nigeria . Method: Stool samples of 116 confirmed HIV positive patients with diarrhoea were collected and screened for Sal
The adherence toAnti Retroviral Therapy in HIV/IDUers compare to non-IDU/HIV infected and non HIV infected cases.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10696); Alaei K, Alaei A, Saeydi M, Mansoori D, Vaziri S;;;; HIV/STI/IDU Counseling & Care center, Kermanshah, Islamic Republic of Iran; One of the main barriers for starting HAART for HIV/IDUs is the misbeleif that they have less adherence to HAART. Methods: In this study 27 HIV infected cases with CD4
The effectiveness of antiretroviral therapy in observed HIV-positive population (Gdansk, Poland).: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10700); Lemanska LM, Jankowska JM, Smiatacz ST, Trocha TH;;;; Medical University of Gdansk, Department of Infectious Diseases, Gdansk, Poland; Background : To study the effectiveness of HAART in observed HIV-infected patients. Material and methods : The study included 131 HIV- infected patients receiving HAART in the Department of Infectious Diseases Medical University of Gdansk between 2001 and 2003. The analysis was performed on patients being under regular
Side effects of NNRTIs in the Modena Cohort.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10704); Mussini C, Bedini A, Borghi V, Cossarizza A, Esposito R;;;; Clinic of Infectious Diseases, Modena, Modena, Italy; In clinical practice it seems that the tolerability, the incidence of side effects and the reason for discontinuation of NNRTIs could be higher than described in the literature. Methods: Retrospective cohort study. An accurate chart review was conducted to evaluate the onset of any side effect related to tr
Metabolic and renal profile before and after tenofovir DF.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10708); Roca B, Gisbert C, Cabestany B, Perez AP, Ventura JM;;;; Hospital General, Castellon, Spain; Metabolic side effects are common with several anti-HIV drugs. Tenofovir disoproxil fumarate (TDF), a non-nucleotide reverse-transcriptase inhibitor, seems to be free of significant toxicity of that kind, although data are scant.
Patterns of hospital services for provision of antiretroviral therapy to persons living with HIV/AIDS by the National 'Access to Care Project' in Northern Thailand.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10712); Panpanich R, Leuseree T, Rumakom P, Baker S;;;; Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand; In the upper north of Thailand , the Access to Care project for provision of antiretroviral therapy was launched in the year 2001. The first cohort took place in 54 hospitals with 819 PLHA. The evaluation study was conducted one year after the ATC project started in 15 hospitals of 5 provinces in N
Dynamics of HIV-1 in peripheral bloods from long term non-progressor (LTNP) to AIDS.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10716); Deng XW, Terunuma H, Munkanta M, Jin HF, Gondwe C, Yamashita A, Kasai H, Kato S, Saito Y, Takashima Y, Hanabusa H, Fujii T, Ishikawa M, Sakai M, Shirahata S, Oka S, Takahashi S, Ikeda S, Miura T, Matuda J, Ito M, Mimaya J;;;; Department of Alternative medicine, University of Yamanashi, Yamanashi, Japan; Aim: The dynamics of HIV-1 in the peripheral blood from LTNP to AIDS is unknown. We investigated it with three methods, trying to evaluate the relationship of HIV-1 viral replication with disease progression. Methods: In this study a cohort of 64 Japanese hemophiliacs with HIV-1 infection were divided into 6 groups. 15
Hepatitis B, C among HIV infected IDUs in Belarus.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10720); Eremin VF, Gasich EL, Blashkevich NV, Barisenko ZI;;;; Research Institute for Epidemiology & Microbiology, Minsk, Belarus; To study hepatitis B , C spreading among young HIV infected IDUs in Belarus . Methods: EIA on HBsAg, anti-HCV, HIV Ag/Ab, Western blot, PCR, RT-PCR, epidemiologycal, statistical. Results: In the beginning of January 2004 cumulative number of HIV-infected patients has reached 5485 (713 new HIV cas
Integrating prevention of mother to child transmission (PMTCT) programme into routine primary health care services.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10724); Sallet J, Nqini N, Olaosebikan AA;;;; Management Sciences for Health, Boston, United States; The national HIV prevalence among antenatal clinic attendees in South Africa has shown an increase from 0.75% in 1990 to 24.8% in 2001 (Eastern Cape - 21.7 in 2001). To address this burden the PMTCT programme was piloted while at the same time addressing operational challenges inherent with introduction of anti
Anthropological aspects of transmission of HIV during pregnancy and birth in Southern India.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10728); Hancart Petitet P;;;; Laboratoire d'Ecologie Humaine et d' Anthropologie, Aix en Provence, France; In some part of India , women of remote rural areas still deliver at home with Traditional Birth Attendant. PMTCT programs are available only in a few health care services. Women delivering at home should also benefit of preventive measures regarding HIV transmission. Prevention should then be adapted to lo
Palliative care for children living with HIV/AIDS in resource limited settings.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10732); Awori Oketch M, Moss V, Sims R, Eriki M, Pearson N;;;; Mildmay Internationa, Jajja's Home, Kampala, Uganda; Issue : Palliative care is effective in children living with HIV/AIDS but unavailable in many resource limited settings (RLS). Description : This paper describes the observed benefits of palliative care for children with AIDS in a RLS. Jajja s Home is a day care centre for children living with AIDS; a model project dev
Effect of antiretroviral therapy on nutritional status of HIV infected children.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10736); De Leon M, Gimenez V, Gutierrez S, Gutierrez G, Cunetti L, Quian J;;;; Centro de Referencia Nacional Materno-Infantil HIV-SIDA/Hospital Pereira Rossell / Universidad de la Republica, Montevideo, Uruguay; Nutritional status is frequently affected in HIV-infected children, particularly the height/age ratio but there are today only a limited number of studies defining growth parameters and nutritional status for HIV children under antiretroviral therapy. To evaluate the effect of antiretroviral therapy (ARV-T)
HIV transmission in home care delivery in South India: the need for a four-fold approach.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10740); Hancart Petitet P;;;; Laboratoire d'Ecologie Humaine et d' Anthropologie, Aix en Provence, France; In Southern India , HIV MTCT programs have been started in some governmental hospitals and by some NGOs but it exist neither in private clinics nor in rural areas. In such context, the distance that separates HIV MTCT recommendations of International Health Organizations from the actual delivery practices may be viewed
Crack use and behavioral risk: A public health challenge.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10744); Garcia EG, Delbon FD;;;; UNIFESP, Sao Paulo, Brazil; According to the Sao Paulo Health Secretariat, HIV rates among youth who use crack-cocaine are rising. Usually, to maintain their drug using habits, youth are thieves and/or engaged in commercial sex. 56% of youth engaged in commercial sex never use condoms, and 46% engage in homosexual relationships. According
Prevention of mother-to-child transmission of HIV in five maternity in Sao Paulo City - Brazil.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10748); Del Bianco R, Dantas S, Seabra JN, Kenj G, Zambone G, Bismarck G, Degni N, Flores O;;;; Hospital Emilio Ribas, Sao Paulo, Brazil; One of the greatest achievements in the prevention of HIV vertical transmission in the last ten years was antiretroviral therapy. The study investigated HIV counseling and the women s acceptance to perform the HIV rapid test, the use of HIV tests in the antenatal and labor periods, and the prevalence of HIV in pregnant
Disparate HIV-1 PCR results of paired plasma samples collected in plasma preparation tubes (PPT) and EDTA tubes (EDTAT): Implications for HAART monitoring.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10752); Zeitlin GA, Handel JL, Greene JB;;;; Physician, New York, NY, United States; HAART efficacy is determined by quantitative plasma HIV-1 RNA. In a large HIV practice the observed rate of virologic failure (>400 cpml) fell dramatically when PPT were replaced by EDTAT for plasma collection. This study sought to compare the consistency of PCR results between these two collection methods.
Personality disorders in a cohort of Peruvian HIV patients.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10756); Bustos R, Collins J, Salazar R;;;; HIV / AIDS Unit, Psychology Branch. G. Almenara Hospital, Lima, Peru; Most studies on personality of HIV-infected patients have been partial evaluations. We aimed to determine the frequency and types of personality disorders in HIV - infected patients. Methods: Descriptive study of all HIV-infected patients evaluated between September 1999 and February 2000 at our psychology
Normal lymphocyte subset ranges in the Afro-Caribbean population and its implications in the initiation of HAART.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10760); Branch SL, Broome H, Abayomi A;;;; Ladymeade reference Unit Laboratory, St Michael, Barbados; Normal lymphocyte subset ranges have been established for Caucasian populations, and have formed the basis of cut off points on which clinical management of HIV and AIDS are made. The Caribbean heritage is predominantly African and there is a scarcity of published ranges for this racial group. As 93% of the
Early initiation of AZT + ddI or AZT + 3TC in HIV-infected infants in resource-limited setting: a muticenter study in Bangkok.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10764); Chokephaibulkit K, Vanprapar N, Pongsamart W, Plipat N, Sutthent R;;;; Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand; An appropriate treatment strategy for HIV-infected infants in resource-limited settings, where HAART is generally not affordable, is still unclear. Initiation with dual NRTI may be an appropriate option for those with less advanced disease. This study aimed to evaluate feasibility, duration of efficacy, and
Personality disorders of HIV-infected patients and risk of antiretroviral therapy failure.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10768); Collins J, Bustos R, Salazar R;;;; HIV / AIDS Unit, Psychology Branch. G. Almenara Hospital, Lima, Peru; There is little information about the potential role of personality disorders of HIV-infected patients on antiretroviral therapy failure. We aimed to determine the association among personality disorders of HIV-infected patients and HAART failure. Methods: Cross sectional study of a consecutive sample of HI
Predictive factors of failure antiretroviral treatment interruption (TI) in chronic stable HIV-infected patients.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10772); Torres R, Cervero M, Jusdado J, Del Alamo M, Solis J;;;; H. Severo Ochoa, Madrid, Spain; Treatment interruptions is an strategy in the management of HIV-infected patients. A predictive model of factors associated with failure TI, could be interesting to support this practice. Methods: We conducted in Spain a follow-up study on 44 patients. We made a multivariate regression analysis to examine p
Personality disorders of HIV-infected patients and risk of death.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10776); Collins J, Bustos R, Salazar R;;;; HIV / AIDS Unit, Clinical Branch. G. Almenara Hospital, Lima, Peru; The potential role of personality disorders of HIV-infected patients in relation to risk of death has been little studied. We aimed to determine the association among personality disorders of HIV-infected patients and risk of death. Methods: Retrospective cohort of a consecutive sample of HIV-infected patie
Periodic presumptive treatment compliance through peer education.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10780); Mhuriyengwe L, Dube N, Wilson D, Muyambo R, Taudzayi T;;;; Institution-Project Support Group, Harare, Zimbabwe; The study sought to ascertain the use of peer education in PPT compliance. Methods: The study was conducted among female sex workers working in seven sites in Zimbabwe . Women were defined as sex workers if they reported accepting money or gifts in exchange for sex. At enrolment, 380 women consented to part
Imaging features of Primary Cerebral Lymphoma (PCL) in Peruvian HIV patients.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10784); Collins JA, Vizcardo R, Rodriguez L, Vega J, Sotelo C, Gutierrez L;;;; Department of Internal Medicine, Division of HIV / AIDS. G. Almenara Hospital, Lima, Peru; The HIV-related PCL is an entity little described in less developed regions. We aimed to determine the imaging features and the rhythm of growth of HIV-related PCL. Methods: Consecutive series of patient with evidence of HIV-related PCL. A radiologist revised the previous Computed Tomography (CT) or Magneti
Behavioral and emotional problems in children with HIV infection compared to children with hematology/oncology diseases and children at a school setting.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10788); Jupimai T, Wicharuk S, Ananworanich J, Siangphoe U, Apateerapong W, Mekmullica J, Sosothikul D, Chomchey N, Koekkoek S, Eggermont L, Cheunyam T, Phanuphak P, Pancharoen C;;;; The HIV Netherlands Australia Thailand Research Collaboration (HIV-NAT), The Thai Red Cross AIDS Research Center (TRCARC), Bangkok, Thailand; : We hypothesize that HIV-infected children have more problems than children with other chronic diseases and normal children. Methods: : A cross-sectional study conducted between Apr-Nov 2003 involving caregivers of 3 groups of children ages 6-16 yrs: Gr 1: HIV-infected. Gr 2: Heme/Onc disease receiving blo
Disease status of the HIV infected women diagnosed during the antenatal voluntary counseling and testing in Barbados.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10792); Singh B, Kumar A;;;; University of West Indies & Queen Elizabeth Hospital, St. Michael, Barbados; In Barbados , voluntary counseling and testing (VCT) for HIV was commenced in early nineties and uptake of this service has been over ninety percent. One of the benefits of VCT, besides use of antiretroviral prophylaxis for prevention of perinatal transmission is to detect HIV infected women early in the co
Modified boosted - p24 antigen can predict HIV-1 RNA viral load (Ampiclor HIV-1 monitor).: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10796); Vanprapar N, Sutthent R, Chokephaibulkit K, Phongsamart W, Chearskul P, Plipat N;;;; Pediatric Infectious Diseases unit, Department of Pediatrics, Siriraj Hospital Mahidol University, Bangkok, Thailand; Decisions to start ART and therapeutic responses are based on the amount of viral load. Ampiclor HIV-1 monitor is a gold standard test, but it is labor intensive, time consuming and expensive. The HIV-1 p24 antigen is not an expensive test, but is not sensitive enough for clinical application. The modified
High incidence and prevalence of hepatitis C virus infection among Bangkok inmates, Thailand.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10800); Paungtubtim W, Thaisri H, Vongsheree S, Sawanpanyalert P, Rojanawiwat A, Sri-ngam P, Jaisue R, Chadbanchachai C, Kongpromsook W, Lerwitworapong J;;;; National Institute of Health, Department of Medical Science, Ministry of Public Health, Nonthaburee, Thailand; High rates of hepatitis C virus (HCV) infection among inmates have been reported worldwide. However, less information on HCV infection and risk factors among inmates in Thailand is available. Method: A prospective cohort of 689 male inmates in a Bangkok central prison was studied during 2001-2
Genotypic Resistance Mutation to Antiretroviral Drugs in Treatment-Naive HIV/AIDS Patients in the Northeast of China.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10804); Shang H, Han XX, Zhang M, Wang YN, Zhang ZN, Jiang YJ, Liu J;;;; AIDS Research Center, the First Affiliated Hospital, China Medical University, Shenyang Liaoning, China; The genetic diversity of HIV- pol gene and PI and RT resistance-associated mutations were studied in 54 seropositive treatment-naive residents of the northeast of China to examine the prevalence of drug resistance mutations in China. Methods: HIV-1 partial pol genes in infected plasma samples were amplified
Mortality according to HIV status in children born to HIV-1 seropositive women at the Dar es Salaam site of the Petra trial.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10808); Massawe A, Karlsson K, Kilewo C, Swai A, Lyamuya E, Mhalu F, Biberfeld G;;;; 1Muhimbili University College for Health Sciences, Dar es Salaam, Tanzania; Background : The objective of this study was to analyse mortality in a cohort of children at the Dar es Salaam site of the UNAIDS multicentre Petra trial (a mother-to-child HIV-1 transmission intervention study using antiretroviral therapy). Antiretroviral treatment was not available in this setting apart from the shor
Social action "Pick your condom".: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10812); Caplinskas S, Caplinskiene I, Nagys Z;;;; Lithuanian AIDS Centre, Vilnius, Lithuania; Background. Problem of premature sexual practices becomes more serious in Lithuania . Condom import doubled in the last 8 years (1995-2002). Condom issues are practically not included into school curricula because of objections of Ministry of Education and Science. Knowledge on safer sex is mainly available in the non-
FDG-PET for early detection of lipodystrophy in HIV-infected patients.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10816); van der Ven A, Bleeker-Rovers CP, Zomer B, Koopmans P, de Geus-Oei LF, Oyen WJ;;;; Department of Internal Medicine, University Medical Center Nijmegen, Nijmegen, Netherlands; Lipodystrophy, an important complication of HAART, is a clinical diagnosis with early features often presenting 12-16 months after initiation of therapy. One hypothesis is that the pro-inflammatory response to HAART causes subcutaneous inflammation resulting in lipodystrophy. Since F-18-fluorodeoxyglucose (
Barriers to patient adherence to anti-retroviral therapy (ART) in Lighthouse Clinic, Lilongwe, Malawi.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10820); Makwiza I, Neuhann F, Chiunguzeni D, Lalloo D, Kemp J;;;; Institution, Lilongwe, Malawi; To explore personal and system-related barriers to adherence to anti-retroviral therapy amongst patients at Lighthouse Clinic. The Lighthouse, a comphrehensive HIV/AIDS non-government service provider which implements the Government of Malawi provision of ART at a cost of drugs to patients in Lilongwe. Meth
Registration of Kaposi sarcoma (KS) in HIV-infected patients (pts) in Russia.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10824); Gruzdev BM, Kravchenko AV, Potekaev NN;;;; Moscow city AIDS Center, Moscow, 105275, Russian Federation; KS is the most common tumor in HIV-infected pts in Russia . The objective of this study was assessment of frequency of registration of KS in pts with HIV. Materials and methods: Pts with combined HIV-infection and KS, hospitalized in Infectious Clinical Hospital N2 of Moscow, have been examined over 16-yr p
Toxoplasmosis in AIDS patients in Moscow, Russia (1998-2003).: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10828); Alyaeva MD, Ermak TN, Kholodilova MA;;;; Russian Federal AIDS Centre, Moscow, Russian Federation; Cerebral toxoplasmosis -one from leading opportunistic infections. The purpose of our work was to study clinical data and toxoplasmosis status in the structure of opportunistic diseases in AIDS patients. Methods: Clinical analysis of all cases of toxoplasmosis among AIDS patients during last 5 year Epidemic
Lugansk Charity Foundation "Anti-AIDS".: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10832); Rjaplov Jury RJ;;;; Charity Foundation 'Anti-AIDS', Lugansk, Ukraine; HIV./A1DS/STO Prevention Among Intravenous Drug Users in LuganskAccording to the latest census there are 525 thousand people living in the city of Lugansk. As of 01.02. 2003., 5875 people who use psychotropic substances for non-medical purposes were registered at the regional narcological dispensary. According t
Immunological development in asymptomatic HIV-1 vertically infected children.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10836); Giovannini M, Salvini F, Zuccotti GV, Cucchi C, Gemmellaro L, Testolin C, Riva E;;;; Department of Paediatrics- San Paolo Hospital- University of Milan, Milan, Italy; In HIV infected children, CD45+CD4+ T lymphocytes reconstitution has been related to efficient thymopoiesis. Because human thymus undergoes spontaneous involution at a relatively young age, institution of antiretroviral therapy early in the course of infection has been recommended. Methods: in 12 HIV vertic
The LOPSAQ salvage study: 48 week analysis of the full cohort treated with lopinavir (LPV/r) plus saquinavir (SQV) without any additional antiretroviral (ART) therapy.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10840); Staszewski S, Dauer B, Carlebach A, Moesch M, Gute P, Klauke S, Stuermer M;;;; JW Goethe-Universitat, Frankfurt, Germany; week data from the initial cohort of the LOPSAQ study was previously reported. This is an extended analysis of the full cohort over 48 weeks. Methods: Cohort study of 163 heavily pre-treated patients who were experiencing treatment failure with an reverse transcriptase inhibitor (RTI)-containing regimen due
Hepatic disorders in Polish AIDS patients.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10844); Mian M, Kozlowska J, Hryniewicz H, Mikula T, Cianciara J;;;; Warsaw Medical University, Warsaw, Poland; To determine the liver status and its effect on the course of HIV infection we undertook an observation of 118 AIDS patients. Methods: A total number of 118 AIDS patients hospitalized in our department during the years 1999-2003 were analyzed (male 91, female 27, mean age 38,1 +/- 9,8, age range 22-70 years
Characteristics of somatic development in HIV infected children (preliminary communication).: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10848); Marczynska MM, Palczewska I, Szilagyi-Pagowska I, Szczepanska-Putz M;;;; Department of Growth and Development of Chlidren and Youth, Institute of Mother and Child, Warsaw, Poland; Background. HIV infection influences somatic development. The introducing of HAART demonstrated clinical, immunological and survival benefits, but also problems with metabolic abnormalities and/or lipodystrophy occurred. The aim was to present anthropometric measurements and to evaluate somatic development of HIV infec
Pegylated IFN alfa - 2a plus Ribavirin (RBV) in HIV/HCV coinfection: disease management of patients treated with HAART.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10852); Orani A, Perini P, Valota M, Castaldo G, Nigro M, Fossati M;;;; Ospedale 'A. Monxoni' - UO Malattie Infettive e tropicali, Lecco, Italy; The main aim of this study is to evaluate the efficacy and tolerability of combination therapy in HIV/HCV coinfected patients, especially those treated with HAART, using the stopping rule testing at 12 week (early virological response: HCV-RNA neg or drop >2 logs ); secondary objectives consider the opportunity
Anaemia in Patients Accessing Antiretroviral Therapy in Ghana: An Observational Study.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10856); Torpey K, Asare R, Nyarko C, Agyeman P, Yanney J, Drah B, Essah K;;;; Family Health International, Accra, Ghana; The use of antiretroviral therapy is associated with a decline in morbidity and mortality and improvement in the quality of life. Antiretroviral drugs is, however, also associated with side effects and toxicity. Anaemia is one of the important side effects of Zidovudine. The W. H. O recommends the use of tw
Legionnaires's disease in HIV infected patients.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10860); Portu J, Aldamiz-etxeberria M, Izagirre M, Tarabini P, Apraiz L, Pinedo A;;;; Hospital Txagorritxu, Vitoria-Gasteiz, Spain; Background : Pneumonia caused by Legionella pneumophila, a significant pathology in inmunosuppressed, has hardly been described in HIV patients. We will describe the pneumonia cases in a sample infected by HIV in a latent tuberculous infection treatment programme. Methods : The Legionella cases were diagnosed by: radio
Access to HIV treatment and Human Rights training for health workers.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10864); Durojaiye E, Awofodu B, Eziefule B, Atuma E;;;; Center for the Right to Health, Lagos, Nigeria; Many people living with HIV/AIDS in Nigeria are denied access to treatment mainly due to unavailability of drugs and discriminatory attitudes of health care workers. In addition non-respect for privacy and breach of confidentiality are rife in the health care sector. This situation often discourages PLWHA to see
Monitoring of HIV-1C Proviral Load using a TaqMan Real-Time PCR Assay.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10868); Gaseitsiwe S, Ndung'u T, Doualla-Bell F, Peter T, Moyo S, Kasipo C, Essex M;;;; Botswana Harvard Partnership, Gaborone, Botswana; Proviral HIV-1 DNA persists in peripheral blood mononuclear cells (PBMCs) and lymphoid tissue even in patients under HAART and is one of the major obstacles to the total eradication of the virus, even if treatment is initiated at an early stage. Monitoring of HIV-1 proviral DNA can be a very important tool
Antiretroviral Therapy in Ghana; Patients' Presentation and Response.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10872); Torpey K, Ampofo W, Nyarko C, Asare R, Antwi P, Essah K;;;; Family Health International, Accra, Ghana; The availability of antiretroviral drugs has converted HIV/AIDS from a terminal to a chronic disease. Antiretroviral drugs have been available in the past five years but the cost has been very prohibitive and unaffordable. Family Health International START program in partnership with the National AIDS Contr
A comparative study of condom use and the prospect of microbicides as an alternative barrier prevention method against HIV/AIDS in Katsina state of Nigeria.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10880); Ukauwa CE, Akinola AA, Ukauwa LN;;;; Public Enlightenment Projects, Katsina, Katsina state, Nigeria; Despite the iNtensive Condom Social Marketing in Katsina [ a core Muslim, Northern state of Nigeria , where the sharia legal system is enforced], as a barrier preventive method against HIV/AIDS, theere has been a very poor compliance/user rate, despite the incidence of the disease in the state. This study t
Notions among healthcare professionals in specialized services within the municipal network of Sao Paulo, Brazil, regarding people living with HIV/AIDS (PLWA) that use drugs.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10884); Costa JA, Lima M, Figueiredo WS, Schraiber LB;;;; Specialized clinic of STD/AIDS Santana - Health Departament - Sao Paulo City council; Work aimed towards PLWA has brought in barriers in professional fields, among which is the difficulty relating to the use of drugs. The objective of this study was to understand how the notions and values among professionals has influenced their care of PLWA that are drug user (DU). Methods: This was a qual
Cultural challenges to recruitment into HIV clinical trials in Lilongwe, Malawi.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10888); Bulla AK, Makandawire NE, Chilongozi DA, Martinson FE, Chasela CS, Manyera R, Salima CF, Wemba CS, Kamanga SE, Kumbanga FF, Dzinyemba WE, Joaki GR, Valentine M, Hoffman IF;;;; UNC Project, Lilongwe Central Hospital, Lilongwe, Malawi; Recruitment of subjects is one step to success in conducting HIV clinical trials in developing countries. Misconceptions about HIV research are common. Methods: A Phase III, randomized, placebo-controlled trial (HIVNET 024) to reduce chorioamnionitis-associated mother-to-child transmission of HIV was conduc
The risk of vertical HIV transmission, as perceived by people living with HIV/AIDS (PLWA), in specialized STD/AIDS services in the municipality of Sao Paulo, Brazil.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10892); Silva NE, Oliveira LA, Franca-Junior I;;;; Specialized clinic of STD/AIDS Santana - Health Departament - Sao Paulo City council; Even considering the importance of prophylaxis against vertical HIV transmission in countries like Brazil , the notion of epidemiological risk does not have the same significance for healthcare professionals and people living with HIV/AIDS. The objective of this investigation was to understand the perceptio
AIDS and pregnancy: the comprehensive care possibilities in the health services.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10896); Landroni MA, Martins CL;;;; Specialized clinic of STD/AIDS Santana - Health Departament - Sao Paulo City council; Although the universalization of antiretroviral therapy for the prophylaxis of vertical HIV transmission was a large advance, the innumerable questions involved in the field of reproductive healthcare attendance actions in the context of HIV/AIDS are far from being resolved in Brazil . The present stu
Patients Response, Adherence and Survival in a pilot ARV program in Nigeria.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10900); Odusoga OL, Ogun SA, Adenekan A, Thanni LO, Salako AA, Dawodu O, Falola R, Osho OB, Oluwole FA, Ogundahunsi B, Ogunfowora S, Daniel O, Oladapo OT, Kolapo K, Boyle BA, Lyton J, Yassky R, Ball SC, Krain A, Jacobs JL;;;; Centre for Special Studies, Olabisi Onabanjo University Teaching Hospital, Sagamu, Nigeria; The epidemic and the devastating effects of HIV AIDS are most felt in Africa. Whereas death and devastation from this deadly virus has been drastically reduced in the developed world by the introduction of combination antiretroviral therapy, Africa is yet to benefit from such management. Methods: With the a
Overview of Harm Reduction Programme at Sankalp in Mumbai to prevent HIVAIDS in drug users.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10904); Donde SS;;;; Sankalp Rehabilitation Trust, Mumbai, India; Addressing HIVAIDS among the injecting drug users requires a framework of harm reduction policies,strategies and activities that aim to limit or reduce the nature and extent of adverse consequences of drug use. Harm reduction activities have been extensively evaluated and are the only proven effective means of preventi
The Complementary Health Trust (CHT) - how research and audit helped secure new service contracts for patients with HIV disease.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10908); Robinson N, Kalmanowitz H, Pedro L;;;; Thames Valley University, London, United Kingdom; To determine whether research and audit can support a voluntary organization in developing patient services and acquire new contracts. Methods: Five independent research studies were carried out (1999-2002). Audit of new patients seeking CAM from CHT at their non-NHS clinicSurvey of HIV outpatients at the C
Telelab - Long-distance Training Methodology: An essential tool for Health Professionals Training.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10912); Souza FT, Ferreira C, Lima BP, Inocencio LA, Scapini R;;;; Brazilian STD/AIDS Programme, Brasilia, Brazil; Brazil is a country that has continental geographic dimensions, so training of health professionals and Biosafety measures regarding laboratory procedures are extremely difficult and expensive. Therefore, in April 1997, the Brazilian STD/AIDS Programme developed a Long Distance Training System for Public He
Prioritizing patient referral - a new Complementary and Alternative Medicine (CAM) service in London.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10916); Robinson N, Kalmanowitz H;;;; Thames Valley University, London, United Kingdom; CAM therapies are widely used by people with HIV disease. The Complementary Health Trust (CHT) (a non governmental organisation) was awarded a new contract to provide CAM services at various South London sites. The service was resource limited and funding provided in any one year was only sufficient to provide
HIV 101: Promoting knowledge and health in a high-risk community.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10920); Miller G, Rowe-Lee-Sykes G, Treadwell M;;;; AIDS Minority Health Initiative, Oakland, CA, United States; Since 1998, Alameda County, California, USA has been operating under a state of emergency because of the rapid rise in HIV/AIDS infections. Oakland residents represent the largest proportion of reported HIV/AIDS cases in Alameda County (over 3500) - 58 percent of these cases are African American. AIDS mortality
Treatment outcomes of HIV patients receiving salvaged HAART.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10924); Ogundahunsi OA, Falola OL, Daniel OJ, Ogun SA, Odusoga OL, Adenekan AA, Osho OB, Krain A, Boyle BA, Jacobs JL;;;; Centre for Special Studies, Olabisi Onabanjo Teaching Hospital, Sagamu, Ogun State,, Nigeria; Access to HAART is increasing among PLWHA in developing countries. It is important to document the treatment outcome in this resource limited settings. Methods: A longitudinal study of HIV patients attending the clinic of the Centre for Special Studies, Olabisi Onabanjo University Teaching Hospital, Sagamu,
Bilateral suppurative parotitis following folliculitis in an HIV-infected patient.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10928); Trape L, Somenzini C, Lupo S, Buscema V, Plasenzotti A, Kohli C, Avancini E, Nannini E, Greca A;;;; Hospital Provincial del Centenario Rosario, Rosario, Argentina; Defects of mucosal, cell-mediated and humoral immunity predispose HIV-infected patients to acquire bacterial infections. Nonetheless, bacterial infection of the parotid gland remains a rare entity in this population. Case: A 24 year-old man with a 5-days history of a pustule lesion (folliculitis) on the fro
Ritonavir boosted double protease inhibitors in salvage therapy.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10932); Shah M, Mihailidis C, Davies E, Mandalia S, Bower M, Gazzard B, Nelson M;;;; Chelsea and Westminster Hospital, London, United Kingdom; Ritonavir boosted double protease inhibitors are one option for salvage patients. This study reviews their efficacy and toxicity. Method: A retrospective analysis of patients who received ritonavir boosted lopinavir (LPV) with
Hematological profile of HIV positive pregnant women in India.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10936); Khandekar MM, Deshmukh SD, Bhore AV, Bulakh PM, Bhosale R, Bharucha KA, Kshirsagar AS, Kawatkar AN, Gupte NA, Bollinger RC, Phadke MA;;;; BJ Medical College and Sassoon General Hospital, Pune, India; Anemia in pregnancy with HIV is a challenging multifactorial outcome. Red cell Distribution Width (RDW-SD) is the first parameter to get affected thus is important in assessing mixed and early deficiencies in mild & moderate anemias. We wanted to predict the cause of anemia using morphological parameter
Determinants of physician attitudes toward communication with HIV/AIDS patients in Ile-Ife, Nigeria.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10940); Ijadunola KT, Odebiyi AI, Ijadunola MY, Aina OA;;;; Obafemi Awolowo University, Ile-Ife, Nigeria; Due to the paucity of information on the process of communication, information seeking and control in relation to HIV/AIDS both globally and locally, we conducted a study to assess the determinants of physicians attitudes toward communication with HIV/AIDS patients in Ile-Ife, Nigeria , and investig
Virological response to salvage saquinavir/ritonavir low dose containing regimen in DMI 2 French cohort: the IN VITO Cohort.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10944); Simon A, Zuckman D, Calvez V, Dantin S, Bergougnoux L, Delfraissy JF, Peytavin G, Costagliola D;;;; Pitie-Salpetriere Hospital, Paris, France; To study the virological response (VR), viral load
The effectiveness of an individualized medication adherence intervention trial.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10948); Holzemer WL, Bakken S, Portillo CJ, Grimes RM, Welch J, Wantland DJ;;;; University of California, San Francisco, San Francisco, United States; This study tested the CAP-IT intervention (Client Assessment Profiling - Intervention Tailoring) in a randomized clinical trial designed to improve adherence to ARVs. The intervention is based upon the nursing care process of conducting a common CAP of client needs based upon the dimensions of the Ickovics
The dispensing of antirretrovirals in Brazilian public health system.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10952); Matchula OJ, Cardenas FE, Fonseca PM;;;; Brazilian Ministry of Health, Brasilia, Brazil; In 1996, with the establishment of Universal Access Policy for ARV therapy, there was an expansion of the Medication Dispenser Unit - MDU countrywide aiming to provide HIV patients with all the necessary ARV medicines. Most of these MDU are linked to HIV/AIDS Reference Health Services. The implementation of thi
Role of peoples leaving with HIV/AIDS(PLWA) in the medical accompaniment for PLWA.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10956); Houngbo R, D'oliveira D;;;; MAP/ Benin, Cotonou, Benin; Since 2002, Benin put in place a fetch Anratovirus (ARV) program. 12 PLWA have been recruited to come with the equal, for working oder of the initiative. Method: About 700 PLWHA are under ARVs treatment in the setting of the Beninese Initiative for ARVs access(IBA-ARV), in the 3 sites open has this effect.
HIV detection in Mexican rural settings: the role of traditional midwifes.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10960); Jimenez S, Loggia S, Gayet C, Taracena R, Magis C;;;; CENSIDA, Mexico, Mexico; The aim of this research is to analyze the role of traditional midwives in the prevention, detection and treatment of HIV/AIDS within rural communities. To do that, the knowledge, beliefs and practice of midwives was investigated as well as the attitudes of a wide range of health actors (public health offic
Atazanavir does not seem to have lipid lowering properties in patients with controlled HIV-infection and normal lipids.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10964); Mauss S, Berger F, Schmutz G, Richter WO;;;; Center for HIV and Hepatogastroenterology, Duesseldorf, Germany; Viral suppression of HIV may rise lipid levels as shown recently (Riddler JAMA 2003, Friis-Moller AIDS 2003). However atazanvir (ATV) did not increase lipid levels in antiretroviral naive patients. For this a lipid lowering effect of ATV to compensate the increase in lipids usually seen with the initiation
Utility of total lymphocyte count (TLC) with readily available markers for predicting CD4< 200 cells/muL in patients on and off HAART.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10968); Mwamburi MD, Ghosh M, Fauntleroy J, Wanke CA;;;; Tufts - New England Medical Center, Boston, United States; Background : WHO guidelines for starting antiretroviral therapy in resource poor settings use a total lymphocyte count (TLC) cutoff of 1250 cells/iL with clinical data but these are developed in populations off HAART. We developed a predictive instrument using TLC and other factors for estimating risk of CD4
Impact of antiretrovirals cost diminution on access to therapy in HIV-positive individuals attending an NGO-funded Clinic in Lima, Peru.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10972); HIdalgo JA, Cabello R, Basurco J, Arquinio L, Ludena J, Alpaca H, Cabrera P;;;; Asociacion Via Libre, Lima, Peru; Some Latin American countries have launched nationwide treatment programs for HIV-positive persons. In Peru , treatment is still available to limited groups of persons through public-funded programs (Social Security). It has been estimated that about 10-15 % of persons requiring antiretroviral therapy (ART)
Pain, anorexia and malnutrition in patients with AIDS: what connections? A clinical assessment in Maputo, Mozambique.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10980); Laurent SG, Jobert J, Alibeu JP, Augusto OJ, Serrie A, Meynadier J;;;; Gabinete da Dor - Faculdade de Medicina, Maputo, Mozambique; Anorexia is a common symptom in the course of the development of malnutrition in AIDS patients, creating the cachexia-anorexia syndrome. Pain is also common in these patients, but the links between these symptoms have still not been fully studied or described, even if pain and cachexia-anorexia have biologi
The appropriate indications of once-daily antiretroviral regimens in treatment naive patients with HIV; results of an international panel study.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10984); Nelson M, Van Lunzen J, Stals H, Stoevelaar HJ;;;; Chelsea and Westminster, London, United Kingdom; Background and aims Compliance problems constitute a major determinant of treatment failure in patients taking antiretroviral medications. Newly available once-daily (QD) regimens reduce the complexity of drug administration and may help to increase the compliance rate. However, little is known about which patients are
Safety and efficacy of highly active antiretroviral therapy (HAART) in a clinical cohort of HIV infected Women.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10988); Walmsley SL, Saskin R, Raboud J, Thompson C;;;; University Health Network, University of Toronto, Toronto, Ontario, Canada; To determine the safety and efficacy of HAART among women followed in a tertiary care HIV clinic in Toronto. Methods: Retrospective chart review of all women initiating HAART (2 NRTIs and either an NNRTI or a PI) since 1997. Results: Of 155 women, mean age 38 years, 81% reported heterosexual transmission, 7%
Emergency contraception in the setting of sexually transmitted disease prevention research.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10992); Zeller KA, VanDamme K, Behets F;;;; Yale University, New Haven, CT, United States; Research conducted in economically disadvantaged sites usually provides participants with standard of care treatment for any complications of the study intervention, and facilitate entry to care for any unrelated medical conditions. Studies of interventions to prevent sexually transmitted disease and HIV, rely
Factors associated with failure to return for HIV result and counseling in a STD clinic population.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10996); Romo-Garcia J, Morales-Carcano A, Leon-Juarez E, Hernandez-Tepichin G, Saavedra Lopez J;;;; CENSIDA, Mexico City, Mexico; Despite the HIV program in Mexico includes counseling, information and support for doing easier testing HIV, however, there is failure in some cases to return for HIV result. The objective of this study is to describe factors that contribute to that failure. In Mexico, the HIV positive subjects lost for fol
Effect of life style and medical contraindications on viral load, CD4 count and adherence.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11000); Grimes RM, Grimes RM, Lal L;;;; University of Texas Helath Science Center at Houston, Houston, Texas , United States; The study objectives were to investigate whether patients receiving HAART regimens that minimize medical and lifestyle contraindications will have better clinical outcomes and improved adherence. Methods: 203 Patients were administered questionnaires that determined the number of medical and lifestyle contr
Effectiveness of HAART among patients initiating therapy with CD4+ cell counts below 200 cells/muL.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11004); Kilaru KR, Kumar A, Sippy N, Roach TC;;;; Ladymeade Reference Unit, st.michael, Barbados; A large proportion of patients present late for HIV testing in Barbados , potentially limiting the advantages of available treatment strategies. We assessed the immunologic and virologic response after 6 months of highly active antiretroviral therapy (HAART) in patients presenting late in the course of thei
Antiviral activity of Abacavir in combination with Tenofovir as backbone of HAART in heavily pretreated patients.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11008); Schewe CK, Adam A, Goey H, Meyer T, Weitner L;;;; Praxis St. Georg, Hamburg, Germany; In prospective studies extremely high rates of virologic failure were observed among treatment naive HIV-infected patients receiving Abacavir (ABC) and Tenofovir (TDF)
Physical functional capacity is impaired in HIV-infected African American males and females, but not in HIV-infected Caucasian males in the southeastern United States.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11012); Phillips KD, Bopp CM, Burgess S, Dudgeon WD, Hand GA;;;; University of South Carolina - Arnold School of Public Health, Columbia, South Carolina, United States; Limitations in physical functional capacity (PFC) can cause premature fatigue and lead to increased morbidity, decreased independence and decreased quality of life (QOL). Causes of decreased PFC in HIV-infected persons include HAART-related mitochondrial toxicity and metabolic dysfunction, decreased oxygen
Haematologic profile of HIV infected children in Lagos, Nigeria.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11016); Adetifa IM, Temiye EO, Akinsulie AO;;;; Department of Paediatrics, Lagos University Teaching Hospital, Lagos, Nigeria; A variety of haematological disturbances can arise in HIV-1 infected persons including children. These manifest as bone marrow abnormalities and peripheral cytopenias. All the three major cell lineages can be depressed in children with HIV infection and progressive HIV disease. These deficiencies are the co
Defining strategies to prevent mother-to-child transmission (PMTCT) of HIV in Brazil.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11020); Vasconcelos AL, Okamura M, Oliveira EC, Ayoub IN, Santos CE, Scapini R;;;; STD/AIDS Program, Ministry of Health, Brazil, Brasilia, Brazil; In Brazil the main difficulty concerning PMTCT of HIV remains the low coverage of HIV+ pregnant women diagnosed and treated. To overcome the problem the Ministry of Health (MoH) launched a project called Projeto Nascer raising the voluntary counselling and testing coverage among pregnant women. Wom
Acupuncture in a group setting reduces the pain and neuropathic symptoms associated with HIV infection.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11024); Phillips KD, Hand GA, Skelton WD;;;; The Mind-Body Research Group, University of South Carolina, Columbia, South Carolina, United States; Pain and peripheral neuropathy are prevalent symptoms of HIV/AIDS that often do not respond to allopathic medical therapy. The present study was performed to determine the effect of 5 weeks of acupuncture treatment in a group setting on pain and symptoms of peripheral neuropathy in HIV-infected individuals.
Maintenance of medication adherence over time.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11028); Gray JR;;;; University of Texas at Arlington, School of Nursing, Arlington, TX, United States; Virtually perfect adherence to HIV medications is a prerequisite of treatment effectiveness. Few studies have documented medication adherence over time in non-research-intense settings, and there is little qualitative data on successful patient strategies to promote adherence. Methods: The study was conduct
Alternative care for AIDS patients: the need to tackle cure claims early.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11032); Matemilola PO, Faransa D;;;; Network of People living with HIV/AIDS in Nigeria (NEPWHAN), Abuja, Nigeria; Testing positive to HIV is a very traumatic and momentous event in the life of PLWAs especially in the developing nation setting where ignorance, poverty and stigma is severe and hardly under any control to date. It is well known and accepted that HIV has no known cure as at today. But every HIV infected person
The counselling workshop: a powerful tool for health providers preventing re-infection and strengthening adherence.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11036); Arellano-Ayala FJ, Martinez-Osorio P;;;; Ave de Mexico, Mexico City, Mexico; The counseling workshop was intended for health care personnel who work in NGO s, universities and public health institutions who interact on a regular basis with HIV positive patients. The objective of the workshop was to provide tools for reducing patient anxiety regarding an HIV positive diagnosis, for e
Helping HIV+ mothers not breastfeeding: a practical guide.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11040); Viana RS, Vasconcelos AL, Aquino KK, Okamura M, Caldas AD, Recine E, Ayoub IN;;;; CGPAN, Ministry of Health, Brazil, Brasilia, Brazil; In Brazil , the PMTCT of HIV program has as a goal the reduction of the transmission risks in uterus/into delivery and to eliminate the transmission risk of breastfeeding. A Practical Guide was developed to help HIV+ mothers and/or caregivers, guiding them to prepare the milk properly, according to baby s age;
Diagnostic yield of stereotactic brain biopsy in cns lesions associated with AIDS.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11044); Yampolsky CG, Corti M, Metta H, Colobraro A, Sevlever G, Benetucci J;;;; Muniz Hospital, Buenos Aires, Argentina; Introduction: Opportunistic infections and neoplasms generally occur in patients with advanced HIV/AIDS disease. If early diagnosis is made, effective treatment can be initiated and improve the prognosis of this patients. Methods: We performed 142 stereotactic brain biopsies to establish the safety, diagnostic yield an
18 Months of experience with HAART in the seaport of Tela, Honduras.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11048); Carbonell C;;;; Clinic Doctors without Borders (Swiss), Tela, Honduras; The Hondura s Government reports to November of the 2003 a total of 19.792 PLWA in the country. It is estimated that 6 thousand people in Honduras need urgently HAART, the National AIDS Program is giving the steps to reach happiness put. Doctors Without Borders works since 1998 in Honduras (Prevention of ST
Analysis of diurnal variation of lymphocyte subsets in healthy subjects and its implication in HIV monitoring and treatment.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11052); Carmichael KF, Abayomi A;;;; LadyMeade Reference Unit, Ministry of Health, St. Michael, Barbados; Absolute values of the lymphocyte subsets are known to be influenced by various biological factors. We set out to determine if diurnal variations in lymphocyte subsets occur in our population and its implication in the monitoring of the immunodeficiency caused by HIV infection. Method: A prospective study w
A simplified method for detection of incident HIV infection.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11055); Ramacciotti TP, Smith D, Cunningham P, Zaunders J, Law M, Kelleher A, Cooper D, Kaldor J;;;; NCHECR/UNSW, Sydney, Australia; We propose a method for classifying newly diagnosed HIV infected persons as incident or as established infections. This method requires no additional specimen processing or test kits, and is achieved solely with results carried out as part of standard screening and confirmation of HIV positivity by the diag
Antiretroviral therapy in HIV-infected Jamaican children.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11059); Evans-Gilbert TD, Pierre R, Steele-Duncan J, Rodriguez B, Whorms S, Figueroa PJ, Christie CD;;;; Bustamante Hospital for Children, Kingston, Jamaica; We describe a cohort of HIV infected Jamaican children receiving antiretroviral therapy (ART) and report the outcomes of this intervention. Methodology: An observational multicentre prospective study was conducted. Children commenced ART using clinical, immunological and compliance indicators. Outcome measu
Resistance mutations in patients with HIV-1 subtype A/E failing their first HAART or non-HAART.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11063); Chan MK, Wong KH, Yam WC, Chan KC, Lee KC, Lee SS;;;; Integrated Treatment Centre, Department of Health, Hong Kong, China; Background HIV-1 subtype may be one of the factors determining the pattern of resistance mutations in antiretroviral treatment failure. Method Twenty-one patients with first treatment failure were recruited, as defined by plasma viral load >1000 copies/ml on >=2 occasions and >95% adherence. Mutations in protease (PR)
Insufficient competence to provide care about HIV/AIDS in doctors of the public health system in Nicaragua: Results of a survey.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11067); Porras-Cortes G, Quant-Duran C, nurinda-Cardenas S;;;; Hospital Bautista, Managua, Nicaragua; Recently the Global Fund of the United Nations has approved a project to improve the care of people living with HIV/AIDS (PLWAs) in Nicaragua supplying prophylaxis treatment for opportunistic infections (OI) and antiretroviral treatment (ART). The two infectious diseases practitioners that have mainly been
Evaluation of CD4 assay formats on the BD FACSArray ® Bioanalyzer.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11071); Varro R, Hoffman RA, Chen CH, Bui N;;;; BD Biosciences, San Jose, United States; Background : BD Biosciences recently released a 2 laser/4 color instrument with integrated plate-loading capability for research use only. Here we report the compatibility of this new platform, FACSArray with different CD4 counting methods. Methods : The FACSArray is equipped with a red laser and a green laser. The red
Painful realities: household surveys as a monitoring tool for HIV/AIDS care and support in Cambodia.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11075); Ly PS, Morineau G, Rubin J, Wolf RC;;;; NCHADS, Phnom Penh, Cambodia; An international work group including WHO/USAID/DHHS(CDC & HRSA)/FHI/Macro developed a standard questionnaire to monitor at household level the care and support services provided to PLWHA and their unmet needs. The questionnaire was piloted in 2 health districts in Cambodia using different sampling
Pharmacy teams as agents for the adherence to antiretroviral treatment among people living with HIV/AIDS (PLWA) who are intravenous drug users (IDU).: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11079); Yokaichiya CM, Figueiredo WS, Schraiber LB;;;; Pharmaceutical Coordination of Sao Paulo City Health Department, NEPAIDS University of Sao Paulo, Sao Paulo, Brazil; In Brazil , IDU account for 23% of AIDS cases among men and 12% among women. Pharmacy teams play an important role in antiretroviral products dispensing and provide services directly to the PLWA. The main goal of this study was to understand pharmacy teams perceptions of their role regarding adherence to HA
Hardware and HAART: cautious erectile dysfunction treatment (EDT) for HIV (+ve) men on highly active antiretroviral therapy (HAART).: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11083); Hudson JH, Doong NC, Shields M;;;; Dr Doong's Surgery, Sydney, Australia; Studies have shown ED has been documented in HIV +ve men on long term HAART however HIV or antiretroviral therapy (ART) does not respectively appear to be a disease or class of drug associated with ED. ED is estimated to affect greater than 50 million men worldwide. In Australia men aged 40-69 have a 34% prevalence of
Divesitel, Help-line: A tool to strengthen adherence treatment process with ARV.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11087); Sosa Meyemberg E, Garcia de Leon-Moreno C, Diaz Pardo N, Placido Rios A;;;; T. AVE de Mexico. AVE de Mexico, Mexico City, Mexico; DIVERSITEL an attention on sexual diversity help-line specialized in therapuetic adherence and implementation of an assessment project on ARV treatment in Mexico City. Training process in several topics were held, including medical, psychological, nutrition, living with HIV/AIDS and adherence topic
Antiretroviral treatment project at angkor hospital for children, Siem Reap, Cambodia.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11096); Heng S, Guhadasan R, Chanphaktra PK, Akao K, Pugatch D;;;; Angkor Hospital for Children, Siem Reap, Cambodia; HIV prevalence in Cambodia is 2.7%, with 5% of cases likely to be in those under 18 years. The HIV clinic started in 2001and has provided Highly Active Antiretroviral Therapy (HAART, from MSF) since June 2003. Outside Phnom Penn, no other project currently provides HAART for children. The criteria
Is peer support the best strategy to improve treatment literacy for HIV affected low-literacy audiences?.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11100); Rosas F;;;; HIV/AIDS Consultant, Ciudad Nezahualcoyotl, Mexico; Treatment literacy is an unmeet need for PLHA from communities with scarce and constrained resources. Peer support has emerged as a major strategy in support adherence to HIV/AIDS treatment. No there educational approaches to train PLHA to each other about how treatment works in their bodies, how to manage drug
Access to care, support and treatment for PLHA in Vietnam: Users' perspective.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11104); Vu Song Ha SH, Hoang Tu Anh TA, Bao VN;;;; CIHP, Hanoi, Vietnam; Vietnam has experienced a rapid increase in the number of new HIV infections; approximately 1300 new cases monthly. Despite many efforts from the government, few people living with HIV/AIDS (PLHA) have access to the full range of HIV/AIDS services. As a part of GIPA program, this study explores experiences
Volunteer-based comprehensive HIV/AIDS program through hotline counseling - Indonesian Red Cross experience.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11108); Sarana L;;;; Institution, Jakarta Selatan, Indonesia; Abstract: Setting up a comprehensive HIV/AIDS program through a volunteer-based organisation -Lessons learnt from Indonesian Red Cross (PMI) Hotline Counseling ServiceStigma and discrimination against PLWHA is a major obstacle in carrying out effective HIV/AIDS intervention programs even in a relatively low pre
Detection of discordant couples in a routine PMTCT clinic in India.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11112); Parameshwari S, Saramini J, Mary sushi K, Samuel NM;;;; DEM , The TN Dr. MGR Medical University, Chennai, India; Back ground: Screening of HIV among pregnant women is an index of prevalence of HIV among the community. Screening of both pregnant women and their husband will play important role in prevention of HIV and reducing mother to Child transmission. Rural PMTCT Programme in India , 8748 pregnant women w
Intrapartum practices to limit vertical transmission of HIV.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11116); Greeff M, Du Preez A, Du Plessis E, Pienaar AJ;;;; Potchefstroom Campus, North West University, Potchefstroom, South Africa; HIV/AIDS is a reality in Africa and because of the high vulnerability of women against HIV/AIDS there arose a need for health service provision to the HIV positive woman to focus specifically on the reduction of the transmission of HIV/AIDS from mother to child. Without the necessary preventative measures a
Mother-to-child HIV transmission rate in Chanthaburi province.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11120); Thaisriwong MR, Poolprasart MR, Thangreur MR, Thaisriwong MR;;;; Chanthaburi Provincial Public Health Office , Chanthaburi , Thailand; On the basis of governmental program for The Prevention of Mother-To-Child HIV Transmission (PMTCT), it is implied to practice into 4 main activities: giving the antiretroviral drug (ARV) to HIV positive mothers during pregnancy and labor, giving the ARV to their infants and replacement feeding. So, this pr
The most frequently lesions of oral cavity in HIV patients in Moscow region (1998-2003).: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11124); Shatohin AI;;;; Moscow AIDS Center, Moscow, Russian Federation; The purpose of work - to study of frequency and clinical manifestation of oral cavity in HIV patients in Moscow region in1998-2003. Methods: We investigated 2000 HIV patients during 5 years. Results: Oral candidiasis was revealed in 85% -in 1998; in 78% - in 2002; 65% - in 2003. Aphtous stomatitis (herpetic
HIV antibody screening: Saliva an alternative to serum.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11128); Balasundaram S, Sunithi S, Kumaraswamy N, Saraswathi TR, Ranganathan K;;;; Ragas Dental College and Hospital , Chennai, India; HIV infection is a major health issue in India , with 4-5 million people infected by end 2003 (National AIDS Control Organization). Given the high burden of HIV infection reliable, rapid screening procedures are needed. Studies have shown that saliva has the potential to be a reliable alternative to blood a
The 3 X 5 HIV/AIDS Treatment plan; Challenges for developing countries from the Zambian perspective.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11132); Chishimba S, Zulu F;;;; Commonwealth ACT-Zambia, Lusaka, Zambia; The World Health Organisation and UNAIDS have launched an ambitious 3 X 5 HIV/AIDS treatment plan. Taking cognisance of the multifaceted dimensions of the pandemic, major challenges, which include policy and operational issues, remain haunting Africa. The feasibility of Zambia s target, 100, 000 PWAs to be on A
External quality assurance in voluntary counseling & testing centres in Southern India.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11136); Mary Sushi K, Mini Jacob S, Viswanath R, Parameshwari S, Samuel NM;;;; Dept.of Experimental Medicine, Chennai, India; The Department of Experimental Medicine is recognized as the National Reference Laboratory (NRL). The External Quality Assurance Scheme (EQAS) is implemented since 2001. The objective of EQAS is standard quality of testing & maintain consistency. It checks the validity of results generated from the Volu
High prevalence/incidence of TB and poor outcomes of TB treatment among people living with HIV/AIDS (PLWHA) in Phnom Penh, Cambodia.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11140); Tamura M, Khun KE, Yuos BH, Yoshiyama T, Okada K, Onozaki I, Mao TE;;;; Faculty of Medicine, Niigata University, Niigata, Japan; Background : TB screening clinic for PLWHA at National Center for TB Control (CENAT) in Phnom Penh, the capital city of Cambodia , was started in November 2001. Methods : The target of the screening was initially PLWHA under a home-based care program and expanded to HIV positive clients of exiting Voluntary Counseling
Incidence of Intestinal parasitic infections in HIV infected and non infected cases.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11144); Alaei K, Jadidian K, Vaziri S, Alaei A, Taherkhani H, Mansoori D, laghaei Z;;;; Kermanshah university, Kermanshah, Islamic Republic of Iran; The spore forming protozoa infect both immune competent and immuno deficient hosts. Methods: in this case-control study we evaluated stool sample of 75 HIV infected patients and 140 cases of general population(randomly)of kermanshah. Results: 75HIV infected patients(69male & 6female)and 140 HIV negative
Study on the outcome of GPO-VIR using at Bamrasnaradura institute.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11148); Ungkasrithongkul SK;;;; Bamrasnaradura Institute, Nonthaburi, Thailand; To determine the efficacy and safety of GPO-VIR (fixed-dose combinations of d4T / 3TC / NVP ) in HIV patients at Bamrasnaradura Institute. Method: The data of HIV patients who initiat
Predictive factors of lopinavir/ritonavir discontinuation for toxicity: results on a cohort of 416 multiexperienced HIV-infected individuals.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11152); Cicconi P, Bongiovanni M, Bini T, Landonio S, Meraviglia P, Testa L, Di Biagio A, Chiesa E, Melzi S, Tordato F, d'Arminio Monforte A;;;; Institute of Infectious Diseases and Tropical Medicine, University of Milan, Milan, Italy; HAART is often associated with adverse events (AE), leading to treatment discontinuation. LPV/r is usually well tolerated, but predictive factors about its discontinuation are still unclear. Methods: Observational study on HIV-patients (pts) starting LPV/r with HIV-RNA>3Log10 and follow-up >3 months. Data o
Efficacy and tolerance of TRIZIVIR® in a cohort of advanced naive patients as first line HAART.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11156); Gallais H, Ravaux I, Tomei C, Colson C, Bouttaz P, Mechin H;;;; Conception Hospital, Marseille, France; To study efficacy and tolerance of Trizivir ® in a cohort of naive advanced HIV-1 infected adults. Methods: Retrospective study evaluating 45 patients receiving Trizivir ® as first line therapy at one site in Marseille ( France ) between October 1999 and October 2
Roles of mutagenically-separated PCR as a tool for monitoring antiretroviral drug resistant HIV-1 in resource limited setting.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11160); Saengaroon S, Wichukchinda N, Myint L, Pathipvanich P, Ariyoshi K, Rojanawiwat A, Matsuda M, Sawanpanyalert P, Sugiura W, Auwanit W;;;; National Institute of Health, Nonthaburi, Thailand; Background : The number of HIV-1 infected individuals receiving antiretroviral drugs has been rapidly increasing in Thailand . It is important to accumulate drug-resistance genotype information of CRF01_AE and to establish a practical system of monitoring drug resistant HIV-1 in an epidemiological scale. Methods : One
Oligodendroglioma in a patient with acquired inmunodeficiency syndrome.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11164); Yampolsky CG, Corti M, Lewi D, Sevlever G;;;; Muniz Hospital, Buenos Aires, Argentina; The primary central nervous system lymphoma (PCNSL) is the principal neoplasm diagnosis to be considered in patients infected with the human immunodeficiency virus type-1 (HIV-1) and focal brain lesions. However, malignant gliomas or other cerebral tumors may often occur in patients with the acquired immuno
Client satisfaction with an upgraded HIV/AIDS Programme: The Barbados Model.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11168); Roach TC, Kilaru KR, Hunte B, Sippy N, Adomakoh N, Adomakoh S;;;; Ladymeade Reference Unit, Ministry of Health, St. Michael, Barbados; In 2001 the Barbados Government, with the financial assistance of the World Bank, undertook a substantial expansion and upgrading of the HIV/AIDS Programme. Key components of this expanded response were the provision of universally available HAART and the provision of a dedicated care and support outpatient
Successful strategies for the prevention of parent to child transmission of HIV: A study.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11172); Nasreen S;;;; Society for upliftment of rural areas, Tirupati-517502, India; The focus of this paper is on the successful strategies tried for the prevention of parent -to-child transmission (PPTCT) of HIV among women in the state of Andhra Pradesh, India . Parent-To-Child Transmission (PTCT) of HIV accounts for less than 1 per cent of all HIV infections (0.73 per cent). Nevertheless, the popul
Diagnostic role of Mycobacterium tuberculosis DNA detection in bronchoalveolar lavage and bronchial biopsy in HIV-infected patients.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11176); Shakgildian VI, Litvinova NG, Kravchenko AV, Leonov ML, Morozova SV, Shipulin GA;;;; Russian Federal AIDS Center, Moscow, 105275, Russian Federation; Now diagnostic role the detection of Mycobacterium tuberculosis (MBT) DNA in bronchoalveolar lavage (BAL) and/or bronchial biopsy (BB) in HIV-infected patients is not clear. Methods: Since 2001 to 2003 136 HIV-infected patients admitted in the specialized department of 2-nd Moscow infectious hospital underw
Monitoring the Quality of Rapid HIV Test Results at VCT Clinics in Soweto.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11180); Makuraj A, Cindi J, Ndou P, Khuno N, Steyn J, Violari A, Gray GE, McIntyre J, Vardas E;;;; Perinatal HIV Research Unit, University of the Wiwatersrand, Johannesburg, South Africa; The Perinatal HIV Research Unit (PHRU) has 14 VCT centers in Soweto, which service antenatal (MTCT) and primary care clinics. There are many HIV rapid testing algorithms used worldwide. The PHRU currently uses the South African government recommendation, which is a screening test Abbott Determine, confirmed
HIV prevention and treatment for IDU in the North Eastern Region of India.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11184); Raj Kumar RK;;;; North East India Harm Reduction Network - NEIHRN, Imphal, India; The North Eastern region of India comprises of seven states which borders Myanmar , China and Bangladesh . Injecting drug use is widespread and not restricted only to certain spots with more hazardous drugs which are non injectable p
Treatment of opportunistic infection and nutritional supplement maintains nutritional status of symptomatic HIV patient.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11188); Falola OL, Ogundahunsi OA, Daniel OJ, Ogun SA, Odusoga OL, Adenekan AA, Osho OB, Krain A, Boyle BA, Jacobs JL;;;; Centre for Special Studies, Olabisi Onabanjo University Teaching Hospital , Sagamu, Ogun State, Nigeria; The coexistence of high rates of malnutrition and HIV/AIDS in limited resource populations creates an additional challege. The lower the BMI, the worse the nutritional status and the general state of health. Methods: Multivitamins, nutrition counselling and salvaged drugs to treat different opportunistic in
Comprehensive care for HIV in a mission hospital, an example from St Mary's Mumias, Kenya.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11192); Gohole AK, Nyagah RW, Onudi O;;;; Family Health International, Kakamega, Kenya; It is generally agreed that HIV should be tackled by a comprehensive approach in which prevention, care and support services are tailored to the clients needs depending on the stage of disease and at which stage of the care continuum they are. FHI/IMPACT and St Marys Hospital have been partnering to
A comparetive study of seropositivity of HIV infection amongst the volantary and replacement blood donors in western rajasthan in India.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11196); Arya DR;;;; S.P.Medical College Bikaner, bikaner, India; Blood is a life saving emergency drug and we shall keep in mind that blood is red and red means danger. Number of biological hazards are related with its transfusion like transfusion of transmitted diseases { TTI }. HIV infection is one of them. In INDIA HIV screening of all the blood/ component and its product is mand
Removing the immediate barriers to HIV prevention among IDUs in Manipur.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11200); Kshetrimayum BK;;;; North East India Harm Reduction Network, Imphal, India; Manipur is home to 40,000 drug users (32,000 IDUs) - estimates the UNODC in their India Country Profile. Spasmoproxyvon (dextropropoxyphene capsules) is widely used and seem to have surpassed heroin use. A recent crack down by an underground outfit of Manipur shot 8 drug users on their thighs and has announced a major
Use of dried blood spots with HIV rapid tests.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11204); Mei JV, Tanuri A, Rayfield M, Hannon WH;;;; Centers for Disease Control and Prevention, Atlanta, United States; Background Many HIV rapid tests are currently available on the world market. In areas where specimens have to be sent to a centralized testing facility, dried blood spots (DBS) are an ideal whole blood specimen that can be transported at ambient temperature. The Centers for Disease Control and Prevention investigated t
HIV-1 Reverse Transcriptase and Protease resistance associated mutations and characteristic polymorphisms in different genetic forms from the Former Soviet Union.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11208); Vazquez de Parga E, Rakhmanova A, Iakovlev A, Munoz M, Valova L, Carmona R, Perez-alvarez L, Delgado E, Thomson MM, Medrano L, Contreras G, Sierra M, Casado G, Osmanov S, Najera R;;;; Instituto de Salud Carlos III, Madrid, Spain; We study of the frequency of resistance associated mutations to Reverse Transcriptase(RT) and Protease(PR) inhibitors in HIV-1 infected patients from countries of the former Soviet Union, and the correlation between genotypic and virtual phenotypic HIV-1 resistance interpretation systems and characteristic
Strucure of fatal outcomes and patological anatomy in HIV-infected patients in Moscow.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11212); Tishkevich OA, Shakhgildian VI, Parkhomenko YG;;;; Clinical Infection Hospital, Moscow, Russian Federation; The important problem for clinicians is to determine the frequency of secondary and opportunistic diseases which lead to the fatal outcome in patients with HIV-infection. It is also critical to determine pathomorphological changes in organs. Methods: The results of 537 autopsies performed in 2nd Moscow Infe
A simple real-time PCR-based reverse transcriptase assay to measure HIV-1 loads of different subtypes.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11216); Heneine W, Hoffmann D, MacInnes H, Simon V, Markowitz M, Pieniazek D, Garcia-Lerma JG;;;; Centers for Disease Control and Prevention, Atlanta, United States; Available RNA virus load (VL) assays are expensive, technically demanding, and sensitive to sequence variation among viral subtypes. Simple and inexpensive assays for measuring viremia are critically needed for patient monitoring in resource-limited settings. We have established and evaluated a simple and s
Efficacy of a generic fixed-dose combination of d4T/3TC/NVP (GPO-VIR) in Thai HIV-infected patients.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11220); Kiertiburanakul S, Khongnarasat S, Sungkanuparph S, Vibhagool A, Rattanasiri S, Thakkinstian A;;;; Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand; Accessibility for HAART in developing countries is limited by the high cost of antiretroviral drugs (ARV). In April 2002, Thai Government Pharmaceutical Organization had launched a low cost (30 USD/month) ARV, fixed-dose combined pill of d4T /
Central Nervous System lesion among HIV-infected patients.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11224); Slavoutskaya OB, Shakhgildian VI, Kozhevnikova GM, Tishkevich OA;;;; Infectious Diseases Chair of the Moscow Medical Stomatological Institute, Moscow, Russian Federation; Background. Etiological interpretation of the CNS pathology among HIV-infected patients is very difficult and important for the timely etiotropic therapy. Objective. To determine the etiological spectrum of the central nervous system lesion. Methods. Since 1992 till 2003, CNS lesion has been detected among 104 HIV-infe
Adherence to fixed-dose combination Zidovudine/Lamivudine versus other NRTI Backbones.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11228); Jordan J, Carranza Rosenzweig J, Delea T, Chernicoff H;;;; GlaxoSmithKline, Research Triangle Park, NC, United States; This study was conducted to evaluate, in the real world, whether the fixed-dose combination of zidovudine + lamivudine (COM) was associated with an improvement in HIV-infected patients adherence to antiretroviral treatment (ART) when compared other NRTI backbones given as separate components. Methods: Using
Prospective audit of a pilot antiretroviral programme for children admitted to paediatric intensive care.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11232); Cowburn CA, Hatherill M, Eley BS, Nuttall J, Hussey G, Reynolds L, Waggie Z, Argent A;;;; Red Cross Children's Hospital and the University of Cape Town, Cape Town, South Africa; This study describes a pilot ART programme for HIV-infected children admitted to PICU, in order to guide an admission policy for critically ill children. Methods: A prospective audit was conducted between February and September 2003. Data collected included: duration of ICU/ hospital admission, HIV status,
Human Resources for Tuberculosis and HIV associated Tuberculosis.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11236); Harries AD, Zachariah R, Bergstrom K, Salaniponi FM, Elzinga G;;;; National TB Control Program, Lilongwe, Malawi; The global targets for tuberculosis (TB) control were postponed from 2000 to 2005, but on current evidence a further postponement may be necessary. Of the constraints preventing these targets being met, the primary one appears to be the lack of adequately trained and qualified staff. We outline the
Immune reconstitution by DHEA- A significant clinical case.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11240); Caprani A, Richert A, Maurisson G;;;; Association Positifs, Paris, France; DHEA prevents TH1 and TH2 imbalance, known to contribute to the progression of HIV. Moreover, HIV+ patients show generally a decline of DHEA blood level. Method: Blood DHEA sulphate(DHEAS), cortisol, CD4 and CD8 counts were measured for an HIV+ patient presenting initially a low DHEAS/cortisol level, during
Stavudine, Lamivudine and Abacavir regimen in HIV Infected Asymptomatic Adults previously treated with AZT-3TC regimen.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11244); Romo-Garcia J, Varela-Trejo MC, Leon-Juarez EA, Hernandez-Tepichin G, Cruz-Palacios C;;;; CENSIDA, Mexico City, Mexico; Null Hypothesis: HIV infected asymptomatic subjects that received AZT + 3TC has the same HIV RNA level at 30 months compared to the same HIV infected subjects that receive AZT + 3TC+ D4T. Methods: A prospective time-series study design was performed in 3
Efficacy and safety of the combination of tenofovir (TFV) and didanosine (DDI) as a backbone regimen.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11248); Panagopoulos P, Antoniadou A, Poulakou G, Katsarolis I, Papadopoulos A, Giamarellou H;;;; 4th Department of Medicine, ATTIKON University General Hospital, Athens University School of Medicine, Haidari, Athens, Greece; Background. TFV, as a NtRTI, is one of the new antiretroviral agents used in HAART. Since TFV combinations have only recently been in use, there is lack of clinical data regarding the co administration of DDI and TFV. Objective. To record the results of an antiretroviral regimen containing DDI + TFV as backbone, in ter
Abnormal MRI/MRS, P300 evoked Potentiel and EEG in HIV -infected HAART treated patients with cognitive troubles.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11252); Poizot-Martin I, Milon MP, Blanquet F, Michotey P, Dinh T, Drogoul-Vey MP, Gastaut JA, Planche D;;;; Hospital Ste Marguerite, Marseille, France; Cognitive troubles in HIV- infected HAART treated patients are actually reported. Methods: We evaluate such patients using brain proton magnetic resonance imaging and spectroscopy (MRI/MRS), P300 cognitive evoked potential (CEP), standard EEG and neuropsychological testing (NP) in such patients. 11 patients
Antiretroviral drug resistance in HIV patients in Kuala Lumpur, Malaysia.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11256); Tee KK, Pon CK, Ng KP, Kamarulzaman A;;;; University of Malaya, Kuala Lumpur, Malaysia; Antiretroviral resistance testing is a significant component in the clinical management of HIV infected patients in many developed countries. In addition surveillance for drug resistant HIV is becoming increasingly important particularly in countries where increased access to HAART is taking place. Data on
Innovative use of electronic technology for HIV medication adherence among urban youth.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11260); Peralta L, Metcalf M, LaGrange R, Cely S, Dongmo S, D'Angelo L, Chandwani S, Koenig LJ;;;; University of Maryland School of Medicine, Baltimore, United States; Research on the use of medication adherence measurement tools among HIV-infected adolescents is limited. The use of Personal Digital Assistants (PDAs), or a handheld personal computer that uses a Palm operating system, to assist adolescents with their HIV medication regimens has not been reported.
Lopinavir/ritonavir (LPV/r) and Saquinavir hard gel (SQV) combination as alternative HAART -regimen for HIV infected patients.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11264); Frixon-Marin V, Solas C, Colson P, Marimoutou C, Drogoul-Vey MP, Vion-Dury F, Dinh T, Orticoni M, Gastaut JA, Poizot-Martin I;;;; Hospital Ste Marguerite, Marseille, France; Antiretroviral therapy for HIV infected patients (pts) with insertion or mutations on reverse transcriptase gene and/or with intolerance to reverse transcriptase inhibitor (RTI) is not yet codified. Methods: To evaluate a protease inhibitors-regimen as alternative HAART regimen in HIV-infected pts with resi
Response to Short Course Chemotherapy in treatment of TB in HIV/AIDS patients in Non-DOTS setting at Tertiary Care Hospital in South Asia.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11268); Wig N, Kumar A, Singh U, Vajpayee M, Sharma SK, Gulati M, Seth P, Wali JP, Pande JN;;;; All India Institute of Medical Sciences, New Delhi, India; At present there is minimal data on the response to Tuberculosis (TB) treatment in HIV patients in South Asia. Methods: We prospectively evaluated the response to treatment of TB in HIV patients at All India Institute of Medical Sciences (AIIMS), New Delhi, India. 85 Patients HIV patients were evaluated for
Total Lymphocytes count is a poor surrogate for CD4+-T- cells count amongst HIV-1 infected clients in Nairobi, Kenya.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11272); Kimani J, Irungu E, Njeri J, Kariri A, Wachihi C, Plummer FA;;;; University of Nairobi- Kenya / Family Health International- Nairobi, Kenya, Nairobi, Kenya; Introduction: Initiatives to scale up access to Antiretroviral drugs in most developing countries are progressing well. However, the required monitoring tests are expensive and still cost more than the lifesaving medications. Therefore, use of a total lymphocyte counts (TLC) of 1200/cumm and below to initiate Antiretro
Eight months of Pilot ARV Program for the poor in Cameroon.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11276); Menyeng L, Bassirou B, Tsague L, Njom Nlend A, Engozo'o A, Eyong C, Musi S, Mossoko J, Macauley I, Monny Lobe M, Tardy M, Kouanfack C, Mapoure N, Thonnon J, Koulla S, Zekeng L;;;; National AIDS Control Committee, Yaounde, Cameroon; In 2000, Cameroun launched a National Strategic Program to fight against HIV/AIDS implemented by the National Aids Control Committee(NACC). Strengthening case management with antiretroviral drugs is one of its main objectives. To achieve this objective average monthly cost of antiretroviral treatment has been r
Influence of Liver Histologic Stage on the Rate of HAART-associated Hepatotoxicity in Patients with HIV and Hepatitis C Virus Coinfection.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11280); Aranzabal L, Moya J, Casado JL, Diz S, Quereda C, Marin A, Moreno A, Antela A, Perez-Elias MJ, Moreno S;;;; Ramon y Cajal Hospital, Madrid, Spain; Background : The presence of co-infection by hepatitis C virus (HCV) is a known risk factor for hepatotoxicity in HIV-infected patients receiving HAART. The aim of this study was to evaluate the relationships between HCV-related liver fibrosis and the rate of HAART-associated liver toxicity. Methods : Prospective cohor
WHO Clinical staging and eligibility for Anti-Retroviral treatment. Too restrictive for patients with a past history of Tuberculosis?: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11284); Teck R, Ascurra O, Gomani P, Pasulani O, Kasamale J, Salaniponi FM, Humblet P, Harries AD, Zachariah R;;;; Medecins Sans Frontieres-Luxembourg, Thyolo, Malawi; Scaling up anti-retroviral treatment (ART) in resource-limited settings requires simplification including the use of clinical criteria for ART initiation. In settings where CD4 counting is unavailable, WHO recommends ART for all individuals in WHO stage III and IV. In HIV-positive individuals aged over 13 y
Evaluation of a new automated system for ultrasensitive HIV-1 viral load monitoring based on magnetic silica extraction and real-time NASBA technology.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11288); Berghuis I, Kreuwel H, van de Wiel P;;;; bioMerieux bv, Boxtel, Netherlands; Background : bioMerieux has developed a new instrument for purifying nucleic acids from various types of specimens. This bench-top instrument is based on bioMerieux s. proprietary Boom technology in combination with magnetic silica particles. Using innovative methods for manipulating the magnetic particles and managing
RNA turnover in HIV/AIDS patients with tuberculosis.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11292); Antuna AP, Barra BC, Grimble GG;;;; Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico, Mexico; Tuberculosis (TB) is commonly associated with HIV infection and singly these diseases have a strong negative effect on nutrition status; together their effect is additive. Whilst TB results in an anabolic block in use of dietary protein, this is not the case in AIDS wasting. Since RNA turnover measured from
Positive health outcome of tuberculosis patients coinfected with HIV in a home based care project: An interventional study.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11296); Deshpande PV, Gogia JS, Thangsing CT;;;; Pathway Project,Project Concern International, Pune, India; Tuberculosis kills more adults than any other single infectious disease in world. The epidemic of HIV has fuel incidence of Tuberculosis especially in developing countries. HIV/AIDS and TB co infection is in the rapid increase as HIV epidemic rapidly rise. Mortality due to Tuberculosis in HIV infected peopl
Low HIV-antiviral failure rate in a well managed clinical setting.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11300); Ohlis A, Bratt G, Reinhard K, Lund B, Karlsson A, Sandstrom E;;;; South Stockholm General Hospital, Stockholm, Sweden; Many studies report antiviral failure in a high proportion of HIV patients on ART, often due to multiresistance. However, there is a lack of reports on long term outcome of HIV-management in routine clinical practice. Method: In Dec 2003 we reviewed all 509 patients at our clinic crossectionally; 95% males,
Enumeration Of CD4 cells In HIV positive patients in a resource poor setting - Jos, Nigeria.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11304); Imade GE, Badung B, Njoku M, Pam SD, Agbaji O, Sagay AS, Idoko J, Sankale JL, Kapiga S, Kanki P;;;; APIN Poject, Jos University Teaching Hospital/ University of Jos, Jos, Nigeria; In an economically depressed setting, the method of choice for CD4 cell count must be precise, accurate, reproducible and affordable. This consideration informed the commencement of an on-going evaluation of a new, no-wash, no-lyse flow cytometric absolute CD4 cell enumerating technique (Cyflow) along side
In vivo Myeloid Cell Purging (MYP) as a therapeutic tool in multi-drug resistant (MDR) HIV patients.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11308); Hasson H, Biswas P, Mantelli B, Malnati M, Vecchi A, Lazzarin A, Beretta A;;;; San Raffaele Scientific Institute and Hospital, Milano, Italy; Background:MDR is a common problem arising upon HAART. Structured treatment interruptions (STI) should induce reversion to wild-type genotype. We performed a study with 12 MDR patients (pts): 6 underwent STI alone (CTRL) and 6 STI plus MYP. MYP is a procedure that selectively traps monocytes and granulocytes with clini
Dihydrocodeine as a pharmaceutical alternative to methadone in the prevention of the transmission of blood borne viruses in injecting drug users.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11312); Robertson JR, McKenzie J, Bruce M, Raab G, Salter A, Storkey H;;;; Department of Community Health Sciences- General Practice, Edinburgh University and Muirhouse Medical Group, Edinburgh, United Kingdom; Background The Asian epidemic of HIV transmission among injecting drug users has recently intensified the urgency of prevention in this group. One area where intervention is problematic is the safe and legal provision of the standard opiate substitute treatment methadone. Limitations have lead to the search for safer a
Anti Retroviral treatment and HIV- positive adults sexual practices.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11316); Owino MA, Wambete M, Chesire LM;;;; Yes Plus, Eldoret, Kenya; There has been considerable public discussion on the impact of advances in antiretroviral therapy (ARV) in sexual practices, but little of this has focussed on arguably the most important affected population, PLWHA. Methodology: The HIV Futures Survey in one region in Kenya collected data in the second
Preparing the public sector for implementing antiretroviral treatment on a large scale.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11320); Makwedini N, Sallet J;;;; Department of Health, South Africa, East London, South Africa; Following the announcement by the South African government to implement Antiretroviral Therapy in the public sector, each province was tasked with preparing their province for the programme. The Eastern Cape Province was no exception and accepted the challenge of a phased approach based on the national plan. De
HIV/AIDS Hotline - a tool for secondary attention of PLWHAs.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11324); Owino MA, Katua A, Henry LH;;;; Yes Plus, Eldoret, Kenya; AIDS hotline is an important tool in the attention of PLWHAs because it is a complete anonymous service, provides a rapid access to information and gives medical and psychological support. To interview PLWHA relatives or friends about the opinion of the services given by the hotline and to explor
Retrospective analysis of antiretroviral interruption in chronically HIV infected patients.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11328); Nogueira RS, Atomiya AN, Leite AG, Bonasser FF, Pereira TC, Segamarchi WS, Terzian AS, Mimicos EV, Fonseca ER, Binelli CA, Madruga JV, Waghabi GR, Magri MC, Caraciolo JM, Kalmar EM;;;; CRT-DST-AIDS and Emilio Ribas Hospital, Sao Paulo, Brazil; The complete eradication of the human immunodeficiency virus (HIV) is still a challenge of the treatment that could not be reached until the present moment. Even after highly active antiretroviral therapy (HAART) the patients are unable to completely eliminate viral reservoirs. Although HAART has contribute
Collaboration between an academic medical center and a community based organization in providing HIV/AIDS care in an urban center.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11332); Lyons C, Cloutier M;;;; University of California SF, Positive Health Practice (PHP) at San Francisco General Hospital, San Francisco, United States; Issue : Linking Academic Medical Centers and Community Based Organizations offers an opportunity to bring high quality medical, psychosocial, and public health care to patients in high incidence, socially and economically distressed communities in order to provide seamless care to multiply diagnosed patients. Descripti
National cooperative study on HIV transmission from mother to child in Japan.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11336); Taniguchi H, Kita T, Tsukahara Y, Hayashi K, Wada Y, Minoura S, Abe S, Sakumoto K, Takano M, Hasuo Y, Hayakawa S, Kitamura K, Yoshino N, Inaba J, Kassai T, Togawa M, Ohba T, Kunikata T, Ozaki Y, Takayama N, Imura S, Totani R, Inaba N;;;; Mie prefectural General Hospital, yokkaichi, Japan; In order to prevent vertical transmission of HIV from mother to child, we retrospectively analyzed clinical information from HIV infected pregnant women and their infants in Japan . Methods: The clinical data were taken from questionnaires to 1716 hospitals that had the department obstetrics and gynecology.
First case of Leishmania/HIV co-infection in Bulgaria.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11340); Valkova I, Kurdova R, Elenkov I, Jordanova D, Filippov G, Iankova M, Gabarska I, Kostov K;;;; Hospital for Infectious Diseases, Sofia, Bulgaria; Leishmania/HIV co-infection is an emerging problem. Immunosuppression resulting from advanced HIV infection increases the risk of Leishmania-infected people developing Visceral Leishmaniasis (VL) which, if untreated, has a mortality rate of almost 100%. In Bulgaria cases of VL are being reported more freque
HIV and fathers - foetal attraction.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11344); Sherr L, Barry N;;;; RFUCMS AIDS Care, London, United Kingdom; Objectives: HIV and reproduction has been women focussed. Testing in pregnancy concentrates on mothers, and parenthood studies examine female perspectives. Fathers and fatherhood are neglected. This study provides an overview on HIV and fathers and explores the views on reproduction and parenthood of Heterosexual and G
Prolonged fever in HIV infected adult patients in Northern Thailand.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11348); Chaiwarith R, Supparatpinyo K, Punjaisee S, Kotarathititum V, Sirisanthana T;;;; Chiang Mai University, Chiang Mai, Thailand; The primary objective of this study was to assess the etiology of prolonged fever in HIV-infected patients in Northern Thailand . We also tried to determine the risk factors of disseminated Mycobacterium avium complex infection (DMAC) in order to predict cases with a high likelihood of having DMAC. Methods:
The women's antenatal care initiative for reduction of HIV mother-to-child transmision in Colombia - The Mother & Child Project - (project funded by the European Commission).: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11352); Arenas Granada CD, Garcia Bernal R, Prieto Alvarado FP, Rincon Ramirez JA, Vargas LE, Gonzalez LA, Ramirez Ramirez CM;;;; Mother & Child Project Coordinator, Bogota D.C., Colombia; This project, based on previous pilot projects conducted between years 2000 and 2002 (approx. 16,000 women tested), is focused on the poorest female population, and based on a intervention integrated to the antenatal care programs. Main project objectives include recognition by Colombian women of the import
Correlation between lipodystrophy. analitical and antropometric variables and therapies in a cohort of HIV-infected patients.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11356); Sala M, Cervantes M, Navarro G, Serrate G, Font B, Segura F;;;; Hospital de Sabadell. Institut Universitari Parc Tauli, Sabadell, Spain; Lipodistrophy (LD): lipoatrophy (LA),lipoaccumulation (LC) or both (LA/LC), is a major concern in the management of HIV-infected patients. It could be correlated with age or sex, body mass index (BMI), waist circunference/waist-to-hip ratio, CD4 count/nadir, %CD4, CD8, HIV viral load, levels of total/HDL/LD
Perceptions and challenges of women who participated in an MTCT clinical trial in Zimbabwe.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11360); Jaji F, Wells J, Shetty A, Munhenga A, Chiwara S, Tanki P, Chirwa J, Jena S, Kambarami R, Maldonado Y, Chipato T;;;; UZ-UCSF Collaborative Research Programme, Harare, Zimbabwe; Thousands of HIV-related clinical trials are currently running internationally. While these trials are closely monitored to ensure that protocols are followed and patients rights are maintained, few research efforts have concentrated on investigating the client s perspective and understanding of participati
Clinical success rate of antiretroviral regimens utilizing a tenofovir/abacavir/kaletra backbone in HAART experienced patients.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11364); Sajadi M, Amoroso A, Gilliam B, Davis C, Redfield R;;;; University of Maryland, Baltimore, United States; Background : Regimens containing abacavir (ABC), tenofovir (TDF), and kaletra (LPV) are commonly used after NNRTI/combivir failures. Recent studies have shown high failure rates in HAART naive patients (Pts) treated with ABC/TDF/
Does palliative care improve outcomes for patients with HIV/AIDS? A systematic review of the evidence.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11368); Harding R, Karus D, Easterbrook P, Higginson IJ, Marconi K, Raveis V;;;; King's College London, London, United Kingdom; The need for palliative care in HIV management is underlined by the high prevalence of pain and symptoms, the toxicities side effects and virologic failure associated with antiretroviral therapy, emergence of co-morbidities, continued high incidence of malignancies, late presentation of people with HIV dise
Rapid Site launch preparation and sequence for scale up of nationwide provision of ARV therapy in Botswana.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11372); Darkoh E, Ramotlhwa SL, Mazonde PN, Riley A;;;; Achap, Min of Health, Gaborone, Botswana; Botswana s National ARV implementation team has reduced new site launch preparation time from over 6 months to between 1.5 and 3 months. __ 1. Letter faxed alerting site to expect assessment visit and to assemble all relevant stakeholders 2. Site faxed a capacity assessment questionnaire to be compl
Self-evaluation of adherence in drugs assumption in adherent and non-adherent HIV+ italian patients.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11376); Visintini R, Ubbiali A, Palermo G, Bregani V, Cattaneo E, Donati D;;;; Health Clinical Psychology Unit, San Raffaele Hospital, Vita-Salute San Raffaele University, Faculty of Psychology, Milan, Italy; Several studies focused on adherence in anti-retroviral therapy, investigated the relationship between patients and clinicians, but only few researches were carried out to assess the role of subjects self-evaluation of their adherence in drug assumption. Aim of this study was to analyse the presence of poss
Quantitative immunological response to HAART is similar even when initiated late: Experience from an Indian cohort.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11380); Pujari S, Patel A, Naik E, Dravid A, Patel K;;;; CHART and Ruby Hall Clinic, Pune, India; Aim: To assess immunological improvement amongst antiretroviral naive HIV infected patients stratified according to baseline CD4 counts on NVP-based HAARTDesign: prospective cohort studySetting: Two tertiary level HIV clinics in IndiaMethod: Antiretroviral naive patients initiating NVP based HAART were recruited consec
Effects of a micronutrient, glutamine, pre- and probiotic enriched liquid supplement on nutritional status and immunity of adults with HIV/AIDS: a pilot study A PILOT STUDY.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11384); Kennedy RD, Labadarios D, Visser J;;;; Medical University of South Africa, Pretoria, South Africa; A randomised double-blind placebo-controlled trial was performed to evaluate the effects of a new micronutrient, glutamine, pre- and probiotic enriched nutritional supplement on nutritional status and immunity in 47 HIV-infected adult volunteers not receiving antiretroviral therapy. METHODS: The interventio
Pros and cons of a phased ARV scale up in Botswana.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11388); Darkoh E, Mazonde PN;;;; Achap, Min of Health, Gaborone, Botswana; Botswana embarked on providing ARV therapy in January 2002 using a phased rather than a big bang approach. There are critical pros and cons associated with this approach Due to lack of any precedent with large-scale ARV provision on the African continent, Botswana deliberately proceeded to implement
Interim results of a study to determine the response to DOTS therapy in HIV seropositive and HIV seronegative tuberculosis in Pimpri Chinchwad Municipality area of Pune, India.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11392); Tripathy SP, Risbud AR, Inamdar VM, Datye AS, Bhausar M, Mehendale SM, Iyer RR, Paranjape RS;;;; National AIDS Research Institute, Pune, India; Aim: To study the response to thrice weekly anti-TB DOTS treatment in HIV seropositive and HIV seronegative pulmonary tuberculosis patients in Pimpri Chinchwad Municipal area of Pune, IndiaMethodology: It was proposed to enroll 120 HIV seropositive and 120 HIV seronegative tuberculosis patients in the thrice weekly DOT
Understanding barriers to pMTCT in Tanzania: findings of a baseline survey.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11396); Ntabaye MK, Lusiola GJ;;;; EngenderHealth, Dar es Salaam, Tanzania; Tanzania has a population of 34.5 million people and it is estimated that national HIV seroprevalence is about 10%. One of the strategies adopted by the Tanzanian government to fight HIV/AIDS is prevention of mother to child transmission of HIV. Methods: EngenderHealth conducted a baseline survey prior to i
Rational compliance and patient heterogeneity: a new way of analyzing adherence data.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11404); Lamiraud K;;;; University of Lausanne, Lausanne, Switzerland; Aherence data are collected more and more often in clinical trials and observational studies. There is no gold standard method to analyze adherence data. Methods: This paper offers a framework for the analysis of adherence behavior which introduces four main dimensions. In particular, our proposed method ac
Building a regional initiative for traditional medicine and AIDS in eastern and southern Africa.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11408); Homsy J, King RL, Tenywa J, Balaba D;;;; THETA, Kampala, Uganda; Issue In sub-Saharan Africa, the majority of the population continues to consult traditional healers (THs) and to use herbal treatments for health care, including HIV/AIDS, yet African traditional medicine (ATRAM) still lacks recognition and credibility among policy makers and the medical establishment. Description The
Atazanavir-based salvage regimens in heavily-pretreated HIV-infected patients.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11412); Dronda F, Moreno S, Antela A, Muriel A, Perez-Elias MJ, Casado JL, Moreno A, Morantes C, Zamora J;;;; Hospital Ramon y Cajal, Madrid, Spain; Atazanavir (ATZ) is a new potent, safe and well-tolerated protease inhibitor with a convenient once daily dose. There is little information about its efficacy in heavily antiretroviral-experienced HIV-infected patients. Data from daily clinical assessment of patients are also necessary for better treatment
Nutritional and cardiovascular risks assessment in african HIV-1 infected patients, abidjan, cote d'ivoire.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11416); Abo Y, Huet C, Minga KA, Dohoun HL, Coulibaly A, Konate S, Bonard D, Dabis F, Salamon R; PAC-CI PROGRAM , Abidjan , Cote d'Ivoire; Background:To describe the nutritional and cardiovascular profile of African HIV-1 infected patients before and at the time of introduction of HAART in Abidjan, Cote d Ivoire . Methods: We selected the first 100 HIV-1 seroconverters of the ANRS 1220 PRIMO-CI cohort, recruited among regular blood donors at the national
Assessing and addressing psychosocial needs within a model of care for HIV-positive youth.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11420); Martinez J, Hosek SG, deBoer D;;;; Stroger Hospital of Cook County and The CORE Center, Chicago, United States; Half of all new infections in the United States occur in youth 13-24 years and very few are aware of their infection. Over 80% of these infections are in youth from communities of color. Medical homes for HIV infected youth require creating both a culturally and developmentally sensitive treatment milieu th
Hepatitis C, dyslipidemia, and disorders of glucose metabolism: a multivariate model.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11424); Markowitz N, Pladevall M, Brar I, Richter A, Lafata J;;;; Henry Ford Hospital, Detroit, United States; Dyslipidemia (DYS) and disorders of glucose metabolism (DGM) have been associated with HIV infection and antiretroviral therapy (ART). This study explored the association of hepatitis C virus (HCV) coinfection with both DYS and DGM among HIV patients (pts) >/=18 years old followed at an inner-city hospital
Tuberculosis: An important HIV-related complication that must shape HIV care programs in less developed countries.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11428); El-Sadr WM, Abrams EJ, Rabkin M, Burman B;;;; MTCT-Plus, Mailman School of Public Health, Columbia University, New York, NY, United States; Tuberculosis (TB) is the most common and deadly HIV-related complication in less developed countries (LDC). Thus, its prevention is of key importance. Interactions between antiretroviral therapy (ART) & anti-TB medicines & weak linkages with TB programs complicate HIV management. Methods: The MTCT-P
Pulmonary hypertension in HIV - infected patients - report of three cases.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11432); Wnuk AM, Bander DC, Boron-Kaczmarska AB;;;; Infectious Diseases Department of Medical University, Szczecin, Poland; Pulmonary hypertension (PHT) occurs with increased frequency among patients (pts) with HIV infection. The development and progression of PHT has no relationship with the stage of HIV disease and the history of opportunistic infections. The pathogenesis of HIV - associated PHT remains unknown. Methods: We re
Patients response, adherence and survival during 3 years of ARV program in Sagamu, Nigeria.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11436); Odusoga OL, Ogun SA, Adenekan A, Thanni LO, Salako AA, Dawodu O, Falola R, Osho OB, Ogundahunsi B, Daniel O, Oladapo OT, Ogunfowora S, Kolapo O, Boyle BA, Lyton J, Yassky R, Ball SC, Krain A, Jacobs JL;;;; Centre for Special Studies, Olabisi Onabanjo University Teaching Hospital , Sagamu, Nigeria; The epidemic and the devastation of HIV continue to ravage Africa. Pockets of experiences across the continent have shown the benefits of HAART in curtailing the spread and in reducing the suffering of people living with the disease. Ethical issues however have prevented many studies from directly comparing
Changes in HIV/AIDS care with expanding capacity for antiretroviral therapy (ART) at a tertiary referral centre in northern Tanzania.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11440); Ole-Nguyaine S, Chu HY, Dolmans WM, Crump JA, Shao JF, Bartlett JA, Thielman NM;;;; Kilimanjaro Christian Medical Center, Moshi, Tanzania; HIV/AIDS care is expanding rapidly in resource-limited settings with the support of training, enhanced laboratory capabilities, and access to medications. HIV seroprevelance in Tanzania is estimated at 10%. The KCMC HIV/AIDS Clinic was started in 2002, and ART was added to the KCMC formulary in 2003. Method
Primary resistance in naive HIV patients with advanced AIDS in Madrid (Spain).: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11444); Goyenechea A, Rivas P, Garcia R, Gorgolas M, Fernandez-Guerrero ML;;;; Fundacion Jimenez Diaz, Madrid, Spain; to assess the prevalence of primary genotypic resistance to antiretroviral drugs in naive HIV patients with AIDS and to determine its association with epidemiological variables. Methods: genotypic resistance tests (LIPA) were performed on plasma samples of 37 naive patients in Madrid ( Spain )
First CD4+ T cell count after the diagnosis of HIV-1 infection in Brazil: opportunity to timely provide an effective antiretroviral therapy.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11448); Lima JN, Inocencio LA, Arakaki D, Vilela WT, Kallas EG;;;; National Program STD/AIDS - Ministry of Health - Brazil, Brasilia, Brazil; Together with making antiretroviral therapy accessible, it is pivotal to provide laboratory monitoring of HIV infection, especially the CD4+ T lymphocyte determinations. This test is important to identify those in need of specific therapy before the development of AIDS-related symptoms. We evaluated the Bra
Factors that have facilitated HIV treatment among injectable drug users with HIV/AIDS in the municipality of Seo Paulo, Brazil, 1996 - 2001.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11452); Mendonca YM, Freitas RC, Kohatsu E, Silva CG, Paiva V;;;; Sao Paulo Health Departament, MEPAIDS< University of Sao Paulo, Sao Paulo -SP, Brazil; Free and universal access to antiretroviral medications in Brazil has brought the challenge of adherence to HIV treatment for the healthcare services. Injectable drug users present greater rates of refusal and abandonment of HIV treatment. This article has the objectives of describing, from the words of inj
HIV seroprevalence, uptake of interventions to reduce mother-to-child transmission and birth outcomes in Greater Kingston, Jamaica -- Funded in part by the Elizabeth Glaser Paediatric AIDS Foundation International Leadership Award 1-ILA-11-01 (CDCC).: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11456); Mullings A, Johnson N, Harvey K, Alexander G, McDonald D, Williams E, Figueroa PS, Smikle M, Palmer P, Whorms S, Christie CD;;;; University of the West Indies, Kingston , Jamaica; The seroprevalence of HIV among pregnant women in the Caribbean is 2-3% and increasing. The Kingston Pediatric and Perinatal HIV Program is developing and implementing a unified program to eliminate MTCT of HIV in Kingston, Jamaica . Methods: Pregnant women presenting to Kingston Metropolitan Antenatal Clin
Determination of HIV-1 p24 antigen associated with erythrocytes: potential uses.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11460); Cena M, Schvachsa N, Garcia MN, Avila MM, Rabinovich RD;;;; National Reference Center for AIDS - School of Medicine, University of Buenos Aires, Buenos Aires, Argentina; a recent study shows that a pool of HIV-1 associated with erythrocytes persists even in patients with undetectable viral load in plasma, being this finding direct evidence for continuing virus replication in these individuals. The basis of this association remains unclear. The aims of this study are to clar
Knowledge, attitudes, and beliefs regarding HIV among pregnant women in rural Tamil Nadu, India.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11464); Srijayanth P, Samuel NM, Read JS, Bethel J, Dharmarajan S, Chamberlin J, Jacob SM, Van Hook H;;;; The Tamil Nadu Dr. M.G.R. Medical University, Chennai, India; Our objective was to assess knowledge, attitudes, and beliefs among a systematic sample of women registered for antenatal care (ANC) at two hospitals in rural Tamil Nadu who are offered education regarding HIV infection and transmission. Methods: Women registered at two public hospitals in Namakkal and Rasi
Intravenous fluconazole therapy In the management of resistant oro-pharyngeal candidiasis in HIV infected children.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11468); Temiye EO, Adetifa IM, Akinsulie AO;;;; Department of Paediatrics, Lagos University Teaching Hospital, Idi-Araba, Surulere, Lagos, Nigeria; Oral manifestations are among the earliest and most common clinical features seen in children and adults with HIV/AIDS. Oropharyngeal candidiasis , which often preceeds and is associated with oesophageal candidiasis,an AIDS defining illness in children, often heralds HIV progression, immune system deteriora
HIV/AIDS quality of care initiative.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11472); Kambarami R, Mugurungi O;;;; University, Harare, Zimbabwe; To improve the quality of HIV/AIDs care in ZimbabweDesign: Description of an initiative and activities for HIV/AIDS care improvement in Zimbabwe. Implementers: Ministry of Health and Child Welfare, Clinicians and clinical researchers Clinical Epidemiology Resource and Training Centre - University of Zimbabwe
Could HAART be safely discontinued in patients that initiated therapy without achieving actual recommended criteria of beginning of therapy?: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11476); Parra-Ruiz J, Martinez M, Munoz-Medina L, Benticuaga M, Pena-Monje A, Martinez-Perez M, Garcia-Garcia F, Hernandez-Quero J;;;; Infectious Disease Unit. San Cecilio University Hospital, Granada, Spain; HAART is burdened by a number of limitations such as elevated long-term toxicity, emergence of drug resistant viruses, poor adherence to life-long regimens, and elevated economic costs. These has led to a progressive delay in the intiation of therapy. As a consequence many patients receiving therapy would n
Opportunistic infections caused by fungi and mycobacterium in a an hospital setting AIDS clinic, in Guatemala City.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11480); Samayoa-Herrera B, Vela CG, Soto I, Lau D, Velasquez T, Paz L, Vargas R, Muralles D, Rivera BE, Arathoon E;;;; Clinica Familiar 'Luis Angel Garcia', Facultad de CCQQ y Farmacia, Universidad de San Carlos de Guatemala, Guatemala, Guatemala; With the emergence of HIV/AIDS, disseminated fungal and mycobacterial infections that were considered rare, are now seen in big number and constitute a challenge to diagnose. The situation worsens in developing countries with limited access to antiretroviral treatment. Methods: A descriptive, retrospective
Results of tuberculosis treatment among HIV+ and HIV- injection drug users.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11484); Minaeva SV, Moshkovich GF, Dunaeva NN, Nikonova SV;;;; Hospital, Nizhniy Novgorod, Russian Federation; HIV-1 and Micobacterium tuberculosis are powerful factors of immunosupressia. Drug use aggravates immunodeficitis. The progress of a tuberculosis at HIV + and HIV- intravenous drug users (IDU) was studied. Methods: During 3 years 47 HIV- (39 male - 83 % and 8 female - 17 %) and 61 HIV + (57 male - 93,4 % an
Co-factors of malnutrition and bad nutritional recuperation of children infected by the HIV/AIDS.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11488); Kitetele Nd FK;;;; F., A.M.L. Makaya L.. Kalembelembe Pediatric Hospital, Kinshasa, Congo, the Democratic Republic of fhe; To determine co-factors contributing to the malnutrition and affecting nutritional recuperation of children infected by the HIV/AIDS. Methods: Assessment of nutritional rehabilitation of children infected by the HIV/AIDS. The study involved eighty (80) children between the age of 3 months and 12 years, who
Adhesion to the treatment of tuberculosis/HIV co-infection: who abandon the treatment of tuberculosis?: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11492); Medeiros LM, Lima SS, Mata DA, Souza SS, Santos RA;;;; The STD/Aids Reference Center of Campinas, Campinas, Brazil; The STD/Aids Reference Center of Campinas, Brazil , has been followed the HIV/TB patients since 1999 according to DOT (Drug Observed Treatment) strategies. During the period of 1999 to 2002, the results showed a increment of tuberculosis cure rate, that increased from 53% to 71%, while the abandon rate was decrease fro
Drug resistance patterns in HIV patients naive to antiretrovirals in Mexico.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11496); Escoto-Delgadillo M, Ramirez-Rodrigez M, Nakamura-Corona A, Lopez-Lomeli MC, Vazquez-Valls E;;;; Centro de Investigacion Biomedica de Occidente, IMSS., Guadalajara, Mexico; This study describes the frequency of antiretroviral drug resistance in HIV positive Mexican population naive to treatment. Methods: 89 patients naive to HIV treatment were enrolled between 2002-2003. The protease (codons 4-99) and reverse transcriptase (codons 37-248) genes were sequenced using TruGene HIV
Mobilization of resources for the unification of criterion to integral attention for people living with AIDS/HIV in occident of Mexico.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11500); Campos-Lopez PI, Perez-Ordaz E, Amaya-Tapia G, Nunez-Flores A, Andrade-Villanueva J;;;; COESIDA Jalisco, Zapopan, Mexico; The specific training events on HIV/AIDS for big groups are generally organized by the capital of the country with federal resources. So, the access and direct participation in the organization are difficult for people living in the interior of the country, even though people living with HIV/AIDS has particular
Antiretroviral drug resistance in patiens with HAART from western and center regions of Mexico.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11504); Vazquez-Valls E, Ramirez-Rodriguez M, Nakamura-Corona A, Lopez-Lomeli MC, Preciado-Negrete FF, Escoto-Delgadillo M;;;; Coordinacion Medica, Direccion Regional de Occidente, IMSS., Guadalajara, Mexico; The purpose of this study was to describe the resistance patterns in HIV patients with more of 18 months in HAART from western and center regions of Mexico . Methods: We enrolled 24 patients from the western region and 76 patients from center region of Mexico. The sequencing of protease (codons 4-99) and re
Prediction of CD4 response in patients achieving HIV suppression - Patient and virus characteristics associated with differential responses to HAART.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11508); Hicks C, Anthony K, Wrinn T, Stout J, Bates M, Hellman N, Patel D;;;; Duke University Medical Center, Durham, NC, United States; Timing of HAART initiation requires balancing CD4 reconstitution potential with toxicity accumulation over time. Analysis of host, viral, immunologic parameters at HAART initiation was done in a cohort of ART-naive patients initiating therapy who achieved VL suppression. This hypothesis-generating study sou
Developing technology to quantify medicines and commodities for PMTCT and ART programs: using Quantimed-HIV in Namibia.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11512); Akhlaghi L, Burn R;;;; Management Sciences for Health, Arlington, VA, United States; Scaling up prevention of mother-to-child transmission (PMTCT) and antiretroviral therapy (ART) programs requires a strong pharmaceutical management system. Rational Pharmaceutical Management (RPM) Plus s pharmaceutical sector assessment in Namibia revealed that data on the use of and demand for drugs and me
Clinical features and outcomes of HIV patients coinfected with MDRTB in Peru.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11516); Hurtado RM, Furin J, Shin SS, Joseph JK, Seung KJ, Palacios E, Rich ML, Mitnick C, Becerra MC, Bayona J, Mukherjee JS;;;; Massachusetts General Hospital and Brigham and Women's Hospital, Harvard Medical School, Boston MA, United States; To examine the clinical features and evolution of patients with MDRTB and HIV receiving individualized MDRTB treatment in Peru . Methods: Retrospective review of coinfected patients treated with individualized MDRTB regimens between 8/96 and 6/03. Results: All patients (n=1397) enrolled in our cohort were sc
Associated Factors and Outcomes of Tuberculosis in Jamaican Infants and Children with HIV/AIDS - Funded in part by the Elizabeth Glaser Pediatric AIDS Foundation International Leadership Award, 1-ILA-11-01 (CDCC).: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11520); Geoghagen M, Farr J, Pierre R, Hambleton I, Christie CD;;;; University of the West Indies, Kingston, Jamaica; There has been a worldwide increased prevalence of tuberculosis (TB) in recent years including in Jamaica and in children attending the UHWI. Data regarding pediatric TB, especially as it relates to all aspects of HIV co-infection is badly needed from developing countries in diverse geographic settings (NIH
Malignant lymphomas in HIV-seropositive patients. Report of 48 cases.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11524); Corti M, Villafane MF, Trione N, Soto I, Esquivel P, Lewi D, Schtirbu R, Narbaitz M;;;; Infectious Diseases F.J.Muniz Hospital, Buenos Aires, Argentina; the incidence of lymphomas in HIV-seropositive patients has increased progressively, specially, at the stage of AIDS. Methods: we report the epidemiology, clinic, virologic and immunologic characteristics of 48 patients with AIDS associated lymphomas. Results: The present series included 48 patients, 42 (87
Rapid oral desensitization to Abacavir in case of probable hypersensitivity.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11528); Ulmer A, Mueller M, Frietsch B;;;; HIV-Practice, Stuttgart, Germany; Diagnosis of Abacavir (ABC) hypersensitivity syndrom (HSS) is not always reliable. Initially in cases of doubt, later on, in probable cases, we tried to transfer a method of rapid oral desensitization to trimethoprim-sulfamethoxazole, as published in 1995, to ABC. Methods: Of 298 patients treated with ABC,
Defining and assessing adherence: a multifaceted approach.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11532); Scott BJ, Charles P, Larson TA;;;; University of Nevada School of Medicine, Reno, United States; Traditionally, the term adherence is patient-focused and is used when describing the propensity of a patient to take medications as prescribed. The objectives of this study were to assess adherence in a broad context that expands the focus to include the patient-clinic interaction. Methods: Specifically, ad
Long-term survival of three patients with lymphomas associated with the human immunodeficiency virus infection.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11536); Villafane MF, Corti M, Lewi D, Tezanos Pinto M, Perez Bianco R, Candela M, Narbaitz M;;;; Infectious Diseases F.J.Muniz Hospital, Buenos Aires, Argentina; Lymphomas associated with human immunodeficiency virus infection (HIV) are an increasing problem with improved survival because of the advances in highly active antiretroviral treatment (HAART). Our objective is to report three HIV positive patients whom developed lymphomas and their long-term survival. Met
A model of care provided by a genital health service in Porto Alegre, Brazil.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11540); D'Elia PB, Ramos MC, Germany C, Carvalho FT, Ouriques C, Both N, Freitas D, Ucalvetti P;;;; CEARGS, Porto Alegre , Brazil; STDs are a serious public health problem in Brazil . Their control is known as a must to reduce HIV transmission. An adaptation of health services to optimize the use of usually scarce resources and to maximize results is of paramount importance. We describe the model of care provided by the Genital Health
Expanding the role of the pharmacist in support of the ART program: A case from Coast Provincial General Hospital in Mombasa, Kenya.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11544); Baya K, Olwande C, Nzumbu L, Thuo M;;;; Ministry of Health, Nairobi, Kenya; Constant availability and rational use of antiretrovirals (ARVs) are key components of a successful antiretroviral treatment (ART) program. In developed countries, the pharmacist has a pivotal role in providing quality ART care in both supply and clinical management. Experiences describing the feasibility of de
Cryptococcus spp. infections in a urban AIDS clinic in Guatemala City.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11548); Soto I, Vela CG, Vargas R, Ortega F, Paz L, Muralles D, Rivera BE, Samayoa B, Arathoon E;;;; Clinica Familiar 'Luis Angel Garcia', Hospital General San Juan de Dios, Guatemala, Guatemala; Background : Cryptococcus neoformans is recognized as one of the most common agent causing fungal meningitis and defines AIDS in HIV positive patients. Objective : To describe the epidemiological and laboratory findings of Cryptococcus neoformans infection in PLWA in an urban hospital clinic in Guatemala
Implementing prevention of mother to child transmission of HIV in rural Guatemala.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11552); Ikeda JM, Sac ML, Maldonado TM, Hearst N;;;; Association for Investigation, Development and Integrated Education, Quetzaltenango, Guatemala; The current program to prevent mother to child transmission of HIV in Southwestern Guatemala is ineffective because little emphasis is placed on motivating health professionals to prioritize HIV infection. We trained health professionals from 6 national hospitals to implement integrated care for the prevent
The right to condoms, sterile needles and information: Cornerstones of HIV prevention under assault.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11556); Csete J, Schleifer R, Cohen J;;;; Human Rights Watch, New York, NY, United States; The human rights of millions of persons to protection from HIV is being violated by actions of governments of affected countries and donors alike. The rising political power of religious fundamentalism, notably but not only in the U. S., has combined with the politics of moral judgementalism, subordination of w
Brazilian multicentric collaborative study developed to determine the rate of Mother to Child Transmission (MCT) of HIV in Brazil.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11560); Succi RC; Sao Paulo Federal University, Sao Paulo, Brazil; Brazil provides free universal access to antiretroviral drugs for AIDS patients treatment and prevention of MCT of HIV. In Brazil vertical HIV transmission cases have been described since 1984. The aim of this multicentric collaborative study was to assess the MCT of HIV rate all over the country
Positive Health Access to Services and Treatment (PHAST): facilitating access and sustained engagement in primary care in a San Francisco adult urban population.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11564); Friend J, Fagan D, Covert K, Wofsy J, Meraz E, Quinn R, Lyons C;;;; University of California at San Francisco, San Francisco, United States; US death rates from AIDS declined remarkably over the latter half of the 1990s, but have leveled off since 1999. A significant proportion of the urban poor are not adequately engaged in HIV primary care. Numerous HIV infected individuals hospitalized at San Francisco General Hospital (SFGH), as well as those ca
Knowledge and seroprevalence of hepatitis B and C among injectable drug users with HIV/AIDS in the the municipality of Sao Paulo, Brazil.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11568); Pra-Baldi ZP, Marchesini AM, Mesquita F, Bueno R, Carvalho HB;;;; NEPAIDS-USP, Sao Paulo, Brazil; The objective of this study was to describe the seroprevalence rates for hepatitis B and C and identify the sociodemographic profile and knowledge of hepatitis among a group of injectable drug users. Methods: A structured questionnaire was applied during individual interviews with people living with HIV/AID
Integrating prevention of mother to child transmission of HIV in maternity centers in rural Guatemala.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11572); Sac ML, Ikeda JM, Queme LM, Maldonado TM, Flores L, Hearst N;;;; Association for Investigation, Development and Integrated Education, Quetzaltenango, Guatemala; In rural Guatemala , 61% of pregnant women deliver their babies with the assistance of midwives in maternity centers or in their homes. We offered voluntary counseling and testing (VCT) to pregnant women during their antenatal control in a maternity center to determine culturally appropriate strategies for
Late-onset, localised, non-tuberculous mycobacteria (NTM) disease in human immunodeficiency virus (HIV)-infected individuals who have undergone immune restoration with highly active antiretroviral therapy (HAART).: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11576); Pett SL, Van Bockel D, Kelleher AD, Munier ML, Zaunders J, Satchell C, Crowe S, Marriott DJ, Milliken ST, Carr AD, McGhie K, French MA, Cooper DA;;;; National Centre in HIV Epidemiology and Clinical Research, UNSW and St. Vincent's Hospital, Sydney, Australia; Disseminated NTM disease is seen in advanced (CD4+ T-cells
Relational database for research site data management with capability for billing, laboratory flowsheets, study drug accountability and screening for potential patients.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11580); Griscti K;;;; NJCRI, Newark, United States; North Jersey Community Research Initiative (NJCRI) is a multi-site clinical trials organization in Newark, New Jersey that conducts industry and federally sponsored trials in HIV/AIDS. Federally funded trials require units to develop and maintain a quality improvement program to ensure accurate and timely d
Identifying microbicide candidates: rationale for selection and approach to screening marketed products.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11584); Camus-Bablon F, Zaneveld LJ, Waller DP;;;; Program for Appropriate Technology in Health (PATH), Seattle, United States; Many of the microbicides in development are new chemical entities with outstanding questions related to their safety, therapeutic use, large-scale manufacture, marketing, and patient acceptance. These issues should be seriously considered before selecting a product for time-consuming and expensive HIV-preve
Diffuse Panbronchiolitis in AIDS.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11588); Tambyah PA, Chai LY, Khoo KL, Kao CP, Lim TK;;;; National University Hospital, Singapore, Singapore; Diffuse panbronchiolitis (DPB) is an unusual condition reported mainly in Japan but also in China and Korea. It is characterised by chronic inflammation and response to macrolides. Untreated, it leads to bronchiectasis and death in around 40% of cases within five years. While other immunological conditions
Coinfection or false positives for Epstein Barr virus and Cytomegalovirus in Primary HIV-1 infection.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11592); Pena JM, Condes E, Barros C, Vazquez JJ, Comesem GE;;;; Hospital Mostoles, Madrid, Spain; Epstein-Barr virus (EBV), Cytomegalovirus ( CMV ) and HIV-1 share modes of transmission and clinical features when primary infection occurs. We present 12 cases of acute mononucleosis-like illness initially diagnosed of primary CMV infection (10 cases) and EBV-induced mononucleosis infectious (2 cases). In
Vertical transmission of HIV-1 1996-2002. Analysis of 277 pregnancies in two university hospitals in Madrid.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11596); Pena JM, Miralles P, Marti C, Munoz MA, Bates I, Ramirez M, Arribas JR, Gonzalez JJ, Berenguer J, Gurbindo MD, de Jose MI, Vazquez JJ;;;; Hospital La Paz, Madrid, Spain; We analyse the profile of the HIV-1-infected (HIV+) pregnant women, antiretroviral therapy, mode of delivery and rates of vertical transmission (VT) in two large teaching hospitals in Madrid. Methods: Medical records of all HIV + women attended during their pregnancy and/or that gave birth from January 1996
Evaluation of abacavir (ABC) plus tenofovir DF (TDF) in multiple drug regimens (MDR).: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11600); Harris M, Harrigan PR, Montaner JS;;;; BC Centre for Excellence in HIV/AIDS, Vancouver, Canada; Recent clinical trial results showed poor virologic outcomes with ABC, TDF, and 3TC in naive patients (pts). We examined the effect of discontinuing ABC in pts taking TDF and ABC in the context of MDR. Methods: Clinic data were reviewed for all pts who took TDF and ABC with >/=2 other ARV drugs and disconti
Occupational exposure to bloodborne pathogens in Brazil - implementation of a national surveillance system (PSBio).: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11604); Rapparini C, Machado AA, Saraceni V, Cortes G; Health Secretariat of Rio de Janeiro (STD/AIDS Program) and Rio de Janeiro's Federal University, Rio de Janeiro, Brazil; Background and Methods: In recent years, occupational hazards faced by health care workers (HCW) have received increasing attention. Although recommendations and guidelines to minimize HCWs exposure to such hazards have been developed, additional information is needed to improve HCW safety. Surveillance of occupational
The meaning of death: perspectives of AIDS and their family members.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11608); Wisesrith W, Nuntaboot K, Sangchart B, Teunnadee R;;;; Khon Kaen University, Khon Kaen, Thailand; Most AIDS patients who are in the last stages of the disease, will be suffering physically, mentally and spiritually. They feel lonely and rejected by society without getting the human respect experience by most other human beings. Therefore, this study was to explore the meaning of death of AIDS patients a
Preparation of pre-antiretroviral therapy (ART) assessment manual to lead good adherence to ART in limited HIV-treatment experience situations.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11612); Watanabe M, Ikeda K, Ogane M, Fukuyama Y, Takeda K, Ito S, Yamada Y, Oka S, Kimura S;;;; AIDS Clinical Center, Tokyo, Japan; To maintain good adherence to ART, a pre-ART assessment of patient s knowledge of ART is essential. In our hospital, HIV/AIDS coordinator nurses have made up a pre-therapy educational manual for antiviral naive patients. Using this manual, 193 out of 226 (93.7%) antiviral naive patients were able to adhere
The setting HIV Clinic by using primary opportunistic infection (OI) prevention program; initial step for the low resource area before HAART program.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11616); Karnkawinpong O;;;; DPC7, Uboratchathani, Thailand; Highly Active Anti-Retroviral Therapy (HAART) can decease morbidity and mortality of HIV/AIDS patients but high cost and resource of this treatment obstruct many patients access to it. Cheaper, simpler in prevention, such as Co-trimoxazole for prophylaxis of opportunistic infections (OI) may be useful for s
Alternative Threatment of PLWHA in Taiwan.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11620); Su YL, Yin JC;;;; Taipei Veterans General Hospital, Taipei, Taiwan; The purposes of this study were to evaluate (1) the needs of long-term care of PLWHA and (2) use of alternative medicine and compliance of HARRT. 191 patients were recruited from the OPD. The great majority dutifully took the precribed medication. The causes of discontinuing treatment included disbelief of drug effects
Homecare and service provision of PHA (Wednesday Friends' Club).: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11624); Tantipaibulvut S, Thakaeng P, Thakaeng S, Wongmaung ma T, Phanuphak P;;;; Thai Red Cross AIDS research centre, Bangkok, Thailand; Problem People living with HIV/AIDS (PHA) has been suffering since they are infected despite various types of intervention programs. As a consequence of the infection, they have to deal closely with medical doctors, nurses, hospital social workers, NGOs, volunteers, etc. However, the current health care se
Toxoplasmosis Seroprevalence in HIV Positive patients in a low resources setting in Buenos Aires Province, Argentina.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11628); Hojman MA;;;; Municipalidad Malvinas Argentinas y Htal. Larcade, San Miguel, Malvinas Argentinas y San Miguel, Argentina; Toxoplasma gondii is among the most prevalent causes of latent infection of the central nervous system thoughout the world. Immunocompromised indidividuals may be at risk for reactivation and disemination of the infection. This reactivation in patients HIV positive may lead to clinically aparent disease, wh
Pregnancy among HIV infected women In Malvinas Argentinas County, Argentina.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11632); Hojman MA;;;; Municipalidad Malvinas Argentinas, Malvinas Argentinas, Argentina; Pregnancy in HIV infected women involves taking chances about vertical transmission and shows the occurrence of sexual relations without preventive measures. Malvinas Argentinas County is low resources settingKnowing caractheristics of pregnancies in HIV positive womenMethods: Retrospective analy
Antiretroviral resistance among HIV infected children experienced to various ARV regimens.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11636); Vanprapar N, Sutthent R, Chokephaibulkit K, Lappra K, Urujchutchairut P, Plipat N;;;; Pediatric Infectious Diseases unit, Department of Pediatrics, Siriraj Hospital Mahidol University, Faculty of Medicine Siriraj Hospital, Thailand; Rationale: One of the reasons failing antiretroviral (ARV) treatment is viral resistance. Genotypic testing with the characteristic mutation in the HIV genome were known to be associated with resistanceIn order to adjust ARV we do the genotypic assays in some of our HIV infected children who experienced vari
A small group of Peruvian HIV patients with Primary Cerebral Lymphoma (PCL).: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11640); Collins JA, Villena J, Loza L, Hidalgo J, Anicama W, Castillo R, Illescas R, Salazar R;;;; Division of HIV / AIDS. G. Almenara Hospital, Lima, Peru; The HIV-related PCL is uncommon and little described in less-developed regions. In Almenara hospital around 2% of the HIV-related intra-cranial disorders are due to PCL. We aimed to describe the clinical and histological features, diagnostic procedure and outcomes of this entity. Methods: Retrospective seri
Genotypic analysis of HIV-1 drug resistance in ARV experienced HIV- infected children.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11644); Lapphra K, Vanprapar N, Sutthent R, Pongsamart W, Plipat N, Chearskul P, Chokephaibulkit K;;;; Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand; Exposure to antiretroviral treatment (ART) may lead to the emergence of drug-resistant mutations. Drug resistant assay have become an important tool to help selecting salvage regimens. It is important to aware of the data on resistant development in children while on therapy. Methods: 23 HIV-infected childr
Establishing community care referral pathway for the HIV positive soldiers and the dependents to receive family support in the village.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11648); Meke H;;;; Military Hospital, Port Moresby, Papua New Guinea; The PNGDF policy that allows full medical examination includes HIV testing for soldiers has given an over whelming task to clinical staff using their experience to establish family care pathway for the HIV soldier repatriated back home if they wish to. Under the defence repatriation policy, soldier
When access is not enough: building a supportive framework for entry into care and long-term adharence -- a concept with global applicability.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11652); Boyer AM, Indyk D, London KJ;;;; Mount Sinai Medical Center, New york, United States; Many infected with HIV do not seek or remain in medical care emen when it is readily accesible. This is particularly true among the impoverished. A home study was done of poor, urban, HIV+ women liming in unstable housing in order to better understand the barriers to care from their perspective. An
Developing practical guidelines to improve HCW safety from blood borne viruses in resource-poor settings.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11656); Tomkins M, Gold J, Bates N, Melling P, Resnik S, Sheather S;;;; Albion St Centre, Sydney, Australia; National and regional guidelines for Infection Control for blood borne viruses (BBV) in Health Care settings are usually based on guidelines from the CDC in Atlanta, USA and aimed at settings where resources and training are not regarded as limiting. These National guidelines are then unable to be implemented i
Utilization of institutional AIDS care in rural Cambodia.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11660); Roeun S, Sin E;;;; Banteay Meanchey Provincial Health Department, Sisophon, Cambodia; Surveillance data from 2003 indicate HIV prevalence in Banteay Meanchey (BMC) Province is among the highest in Cambodia . As the number of persons with HIV progressing to AIDS diagnosis increases, there is a greater need for care and treatment of opportunistic infections (OIs). Many deaths due to OIs can be ave
The efficacy of adolescent substance abuse treatments for reducing substance use and HIV risk behaviors.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11664); Waldron HB, Hops H, Turner CW;;;; Oregon Research Institute, Eugene, OR, United States; Adolescents who abuse substances are particularly at high risk for HIV/AIDS infection. Adolescent substance abuse treatment, then, presents a prime opportunity for intervention on HIV/AIDS risk behaviors within this population. Findings will be presented from two randomized clinical trials for substance-abu
Relevance of clinical expertise in the Initiation of treatment or otherwise in pediatric HIV in a resource limited setting.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11668); Omo-Igbinomwanhia NE, Downes A, John D, Thomas C, John M, Stapleton S;;;; Institution, Tunapuna, Trinidad and Tobago; This study stands to emphasize the need of Clinical expertise and good judgment in the management of Pediatric HIV infection. 77 children were enrolled in this observational study in a center Cyril Ross (SVP) Nursery for children living with HIV/AIDS in Trinidad and
Reasons of HIV test refusal among pregnant women counseled through the PMTCT project in Georgia.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11672); Butsashvili MJ, Kajaia MS, Kamkamidze GK;;;; Maternal and Child Care Union, Tbilisi, Georgia; Elizabeth Glaser Pediatric AIDS Foundation Call to Action project is operating in Georgia. The project includes voluntary HIV counseling and testing of pregnant women. The goal of this study was to assess women s attitude towards voluntary HIV testing, barriers to testing and factors associated with test ac
Is there a role for Co-Trimoxazole prophylaxis in HIV exposed but uninfected children?: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11676); McNally LM, Jeena PM, Gajee K, Sturm AW, Bishop K, Cassol S, Thula SA, Goldblatt D, Tomkins AM, Coovadia HM;;;; Institute of Child Health, London, United Kingdom; PCP is an AIDS defining illness and a common cause of paediatric admission in HIV endemic areas. The WHO recommends that PCP prophylaxis in HIV exposed children continues to the age of 15 months but suggests it is stopped earlier if HIV infection has been ruled out by PCR. Methods: Children aged 1 to 59 mon
Failures to solve violation of children rights.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11680); Pakakong MS;;;; Ngo, Surin, Thailand; Affected children s rights. The research studies on children in Baan Khaw Sarn orphanage in Udorn Thani Province whose rights are violated because a school has denied them to study there. This orphanage is a governmental organization taking care of children, whom their parents died or abandoned and
Tuberculosis treatment adherence and cure rates in an urban South African clinic.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11684); Tison G, Kharsany AB, Lurie MN, Abdool Karim SS, Abdool Karim Q;;;; Brown University, Providence, RI, United States; HIV infection has greatly contributed to tuberculosis resurgence, exacerbating the epidemic already responsible for nearly 3 million deaths annually. The Directly Observed Treatment, Short-course (DOTS) model is currently the standard of care for TB treatment in developing countries. It is important to unde
Review of a workplace based antiretroviral program: the Kenya Ports Authority experience.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11688); Munyi J, Morris CN;;;; Kenya Ports Authority, Mombasa, Kenya; Antiretroviral use in the workplace in Africa is still in its infancy. There is a paucity of information on the optimum mechanisms for delivery and potential pitfalls of these programs. The Kenya Ports Authority which currently has 5,471 employees, recognized the impact of HIV on its workforce in t
West Nile Virus meningitis in an HIV infected patient.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11692); Doonquah LA, Jenkins V, Frederick WR;;;; Family and Medical Counseling Services, Inc, Washington,DC, United States; Since the outbreak of West Nile Virus (WNV) infection in the summer of 1999 in New York City, there has been a dramatic increase in the number of cases throughout the USA. However there are no reported cases of this infection in HIV-infected individuals. Thus, little is known about the incidence, prevalence
Preparing for a New HIV Outpatient Clinic in Vietnam.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11696); Ho AV, Trinh TT, Do NT, Vu TT, Cosimi L, Higgins L, Kamb ML, Luu CM;;;; CDC/Global AIDS Program - Vietnam, Hanoi, Vietnam; HIV/AIDS outpatient services are an important component of comprehensive HIV prevention program around the world; however, the HIV/AIDS outpatient models are quite new to healthcare workers in Vietnam . The National Institute for Clinical Research in Tropical Medicine in Hanoi has recently opened a new outpatien
Recent changes in the hazard function in Japanese hemophiliacs with HIV-1 due to an increase of serious liver disease associated with HCV.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11700); Tatsunami S, Taki M, Mimaya J, Shirahata A, Yamada K;;;; Department of Medical Statistics,St. Marianna University School of Medicine, Kawasaki, Japan; Following the marked improvement in clinical status resulting from the introduction of highly active antiretroviral therapy, serious liver disease is now the major causes of death in the HIV-1-infected Japanese hemophiliacs. Therefore, continuing surveillance of HIV-infected hemophiliacs is absolutely neces
Identify the reasons why some women refuse to announce their VCT result to their partner.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11704); Mwewa Kiri A, Mwadi Kadi A, Dr Mutachi M;;;; The Society of Women Against Aids in Africa , Kinshasa, Congo, the Democratic Republic of fhe; Objectives: Identify the reasons why some women refuse to announce their VCT result to their partner. To set up strategies that can influence women behaviour and help them to reveal their result to their partner after testing positive to HIV/AIDS. Methods: An anonymous survey was conducted among 350 pregnant women who
A clinical diagnostic approach for tuberculosis in HIV infected children is justified.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11708); Frederix K, Petdachai W, Wilson D, Cawthorne P;;;; Medecins Sans Frontieres, Belgium, Bangkok, Thailand; Issues : The diagnosis of Tuberculosis (TB) in HIV infected children is a major challenge in the implementation of HAART programs and is often based on obtaining confirmation by tests that are notoriously insensitive resulting in under-diagnosis and under-treatment. We describe our experience using an adapted diagnosti
Out-Patient Clinics as an alternative for HIV Care and treatment in Vietnam.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11712); Do NT, Vu TT, Trinh TT, Ho AT, Kamb ML, Chong SP, Luu CM;;;; Vietnam Ministry of Health - LIFE-GAP Office, Hanoi, Vietnam; Vietnam reported 74,680 HIV and 11,424 AIDS cases on November 30, 2003. ARV treatment is limited while prevalent stigma and discrimination make HIV infected people conceal their HIV status, and many of them transmit the virus unintentionally or deliberately to others, including their partners and children.
Safer sex for pregnant women in Zimbabwe: A Continued Challenge.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11716); Kahwemba M, Wells J, Shetty A, Nyikadzino L, Samuriwo P, Chitibura L, Kambarami R, Chipato T;;;; UZ-UCSF Collaborative Research Programme, Harare, Zimbabwe; In Zimbabwe , pregnant women find it difficult to discuss sexual and reproductive health issues with their partners, close family members or friends. Their influence, while meant to be supportive in nature, often serves as an obstacle to remaining HIV-negative. 200 pregnant women presenting for ant
Immune response to TB treatment in pregnant women at King Edward VIII hospital, South Africa.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11720); Khan M, Pillay T, Moodley J, Adhikari M, Sturm W;;;; Department of Obstetrics and Gynaecology, Nelson R Mandela School of Medicine, Congella, South Africa; KwaZulu Natal sits at the epicentre of the TB and HIV-1 epidemics. In the antenatal population at King Edward VIII hospital, the incidence of TB increased from 0.1% to 0.6% between 1996 and 1998 respectively, mirrored by an increase in HIV-1 infection from 24% to 28%. Against this background, a prospective
Long term antiretroviral therapy in HIV-infected patients with or without inhibitor regimen does not affect endothelial function.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11724); Cotter BR, Kwan OL, Currier JS, DeMaria AN, Torriani FJ;;;; University of California San Diego, San Diego, United States; Antiretroviral therapy (ART) may predispose HIV patients to accelerated atherosclerosis. Endothelial dysfunction may be an early event in atherogenesis and is associated with coronary artery disease. Impaired flow-mediated dilation (FMD) of the brachial artery in HIV patients on protease-inhibitors (PI) was
The rapid expansion of TB, malaria, HIV/AIDS in the health district inside rebel held areas in the Katanga province of DRC.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11728); Mutach K, Mwadi Kadi A;;;; The Society of Women Against Aids in Africa (SWAA/RDC) , Kinshasa, Congo, the Democratic Republic of fhe; Object: To demonstrate that armed conflicts has a serious impact and prevents health institutions to function well. To expose the vulnerability of the population in war torn areas concerning tuberculoses, HIV/AIDS and malaria. Methodology: Because of the high morbidity and mortality rate, an investigation was lead in t
A Malawian experience - different strokes for different folks a case for alternative and complimentary therapy.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11732); Mapemba S;;;; University of Malawi Chancellor College , Capital City, Malawi; Sub-Saharan Africa is the most affected region by HIV/AIDS in the world and is estimated to have 28 million people living with HIV/AIDS ( UNAIDS 2003). Malawi is a multi-ethnic state located in Sub-Saharan Africa with a population of 10 million people. Over 89% of the population living in rural areas and only 60% have
Efavirenz plasma concentrations in Cambodian HIV-infected patients.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11736); Taburet AM, Segeral O, Ketem A, Ouk V, Hak CR, Bocquentin M, Keo CL, Delfraissy JF;;;; Hospital Bicetre, Kremlin Bicetre, France; Background : To describe efavirenz (efv) plasma concentrations in low weight Cambodian HIV-infected patients (pts) starting HAART and discuss results in relation to tolerance. Methods : 21 pts from the Esther cohort were enrolled; characteristics at inclusion were (median, min-max): age 35, 25-55 yrs, weight 49, 24-62
Clinical signs of immonosupression in HIV infected orphans.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11740); Amukoye EI, Kumon K, Chakaya JM, Bii C, Ouko T;;;; Kenya Medical Research Institute, Nairobi, Kenya; There is an estimated one million HIV orphaned children in Kenya . Some of these children are also HIV infected. Kenya is a poor country with about 60% of people earning less than One United States dollar per day. The government of Kenya has now started distributing free ARV to a few selected HIV infected persons, and
Working together to provide appropriate HIV/AIDS care and treatments.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11744); King GW, Ardphoon P;;;; AIDS ACCESS Foundation, Bangkok, Thailand; PLWHA are not receiving access to appropriate care and treatments. The knowledge and skills in providing care, treatments and support to PLWHA is limited. A model to assist in the development of appropriate HIV AIDS care and treatments programs in resource poor settings. A pilot regional HIV AIDS c
Sclerotherapy in treatment of rectal prolapse in children with HIV/AIDS.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11748); Dattani PG;;;; Tumbi Special Hospital, Dar-es-Salaam, Tanzania; As with any other patients with lowered resistance, wound healing in post surgery HIV/AIDS patients can be complicated: infection, delayed healing etc. A need arises for non-operative management trial before resorting to surgery for HIV/AIDS patients with recurrent rectal prolapse refractory to conservative
Improvement of lipidic assestment and of lipodystrophy in HIV-experienced patients during prolongued antiretroviral treatment interruption (PTI).: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11752); Martinelli C, Giuntini R, Ambu S, Fiorelli C, Bartolozzi D, Farese A, Leoncini F;;;; Infectious Diseases Unit, AOU Careggi Hospital, Florence, Italy; to evaluate virological, immunological, metabolic and clinical consequences in chronically infected HIV patients after interruption of TARV for the presence of lipodystrophy/dyslipidemia and after re-introduction of TARV. Methods: 25 patients, 20 males and 5 females, aged between 31-56, HIV positive since a
Institutional care in the continuum of care for HIV AIDS in Cambodia. A Calmette Hospital experience.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11756); Ouk V, Lefait-Robin R, Segeral O, Hak CR, Heng TK, Delfraissy JF;;;; ESTHER/Cambodge, Phnom-Penh, Cambodia; The first case of HIV in Cambodia was known since 1991. The prevalence of HIV within the 15-49 aged population was estimated at 3,3% in 1997. The government of Cambodia has launched a program of prevention (100% condom use). The sentinel surveillance set up since 1996 shows clearly that the prevalence of HIV is
A comprehension approach to improve the Prevention of Mother to Child Transmission of HIV (PMTCT) in a maternity ward in Phnom Penh.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11760); Kruy LS, Lefait-Robin R, Lemercier D, Leng L, Ouk V, Heng TK, Delfraissy JF;;;; Calmette Hospital, Phnom Penh, Cambodia; In Cambodia , the prevalence of HIV+ in pregnant women population is estimated at 3% and 35% of new infected cases/year are children born from infected mothers. A program for Prevention of Mother To Child Transmission of HIV (PMTCT) has been launched by the government. The maternity ward in Calmette
HIV genome mutations at beginning of HAART affect therapy outcome.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11764); Schmidt RE, Suehs W, Stoll M, Weber K, Rasche S, Heiken H;;;; Department of Clinical Immunology, Hannover Medical School, Hannover, Germany; Antiretroviral therapy of HIV infection may be limited due to side effects and development of resistance. It is therefore important to study the influence of changes in the HIV genome. There are multiple known mutations of HIV directly causing resistance against antiretroviral drugs. We analysed the influen
Home-Based Care services to PLWHAs.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11768); Odiembo LO;;;; The Association of People with AIDS in Kenya (TAPWAK), Nairobi, Kenya; People living with HIV/AIDS (PLWHAs) need love, support, care, understanding and acceptance from the community. Project: The Association of People With AIDS in Kenya (TAPWAK) has embarked on Home Based Care (HBC) activities. Under the current situation of the increasing number of full blown AIDS, most PLWHAs wil
Scaling up the TB/HIV collaborative activities through a participatory action research with active involvement of people with HIV in a general health service setting.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11772); Chaita I;;;; Chiang San Hospital, Chiang Rai, Thailand; In Thailand , a community hospital is a general health service where diagnosis and treatment for tuberculosis (TB) and HIV are available. Yet, the prevention and care model for TB associated HIV is not well established. It is not known how to provide service to the population affected by the dual epidemic in th
Adherence approach in ampath.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11776); Owino RK, Kimaiyo SJ, Mamlin JJ;;;; Moi University and Moi Teaching and Referral Hospital, Eldoret, Kenya; There is need of adopting a practical approach while dealing with adherence. Through experience, AMPATH has adapted a client centered approach to ensure adherence. A relationship is established first between client and providers. Tracer cards are filled and permission for care granted. PLWA support groups
Acceptance of Pmtct in antenatal setting at nsambya Hospital Kampala Uganda.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11780); Namande J, Musoke R, Nayiga I, Mukasa M, Okong P;;;; Nsambya Hospital, Kampala, Uganda; Introduction: Since the conclusion of research on use of ARVs prophylaxis in the late 1990 s. Public health programmes have started implementing ARV prophylaxis to reduce vertical transmission in a low resource settings. Objectives: To describe acceptance of VCT and enrollment in PMTCTMethod: Interview with ANC clients
What is the clinical relevance of the drug interaction between nevirapine and rifampicin?: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11784); Autar RS, Mahanontharit A, Anekthananon T, Sankote J, Ubolyam S, Kornkitsuwan P, Cooper D, Lange L, Phanuphak P, Burger D, Ruxrungtham K;;;; The HIV Netherlands Australia Thailand Research Collaboration (HIV-NAT), The Thai Red Cross Aids Research Center (TRCARC), Bangkok, Thailand; The clinical management of HIV and tuberculosis (TB) co-infection is complicated by drug-drug interactions. One such drug interactions, between nevirapine and rifampicin, is based on the Cytochrome P450 enzyme system. Nevirapine is primarily metabolized by CYP3A4 wh
HIV positivity among multi-drug resistant tuberculosis patients.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11788); Kalpana S, Valladurai N, Ranganathan D, Manjula D;;;; Dept of Epidemiology, TN Dr. MGR Medical University, Chennai, India; A study of drug resistance tuberculosis and HIV status was undertaken in patients with smear positive and smear negative tuberculosis patients in order to define their levels in new smear positive patients. Methods: Patients with the symptoms of tuberculosis, relapsed, defaulting cases were included in this
Tuberculosis co-infection complicates antiretroviral program initiation in Cape Town, South Africa.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11792); Bekker LG, Matoti K, Orrell C, Badri M, Wood R;;;; The Desmond Tutu HIV Centre, Institute of Infectious Disease and Molecular Medicine, University of Cape Town., Cape Town, South Africa; The current South African antiretroviral roll out program makes treatment available to patients with advanced HIV infection. The high tuberculosis prevalence in Cape Town means that most of these patients will have been exposed to tuberculosis (TB) and have had at least one bout of TB treated in the last 5 year
Enhancing Aherence to HAART for People Living with HIV-Infection: "The School for Adherence Enhancement".: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11796); Belyaeva VV, Kravchenko AV;;;; Russian Federal AIDS Center, 105275, Moscow, Russian Federation; One of the main difficulties encountered in the use of HAART with patients living HIV-infection is the lack of adeqaute adherence. The aims of this project were to develop methods of group-based and individual counselling of patients in order to enhance their adherence. This was achieved through the creation of
Reducing hospital care burden of HIV/AIDS patients.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11800); Sothy S, Vanarith C, Sothy R, Bun Leng H, Spencer JN;;;; Institution, Phnom Penh, Cambodia; Cambodia is one of the poorest countries in Asia, it has faced a serious HIV epidemic for more than 10 years. Many people living with HIV have developed AIDS and require medical care and treatment. HIV positive individuals showing up at hospitals are often poor and abandoned persons and use hospitals to live th
Data Warehouse Development for the Brazilian STD/AIDS Programme.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11804); Goncalves BM, Araujo LV, Ferreira JE, Sabino EC, Brindeiro R, Diaz R, Tanuri A, Oliveira SM, Lima JN, Dantas MC, Grangeiro A;;;; IME - USP, Sao Paulo, Brazil; The Brazilian STD/AIDS Programme has implemented 3 operational systems (SICLOM, SISCEL and SISGENO) to control activities related universal access to antiretroviral treatment for people living with HIV/AIDS. SICLOM helps the logistics of the drugs distribution, SISCEL controls the results of viral load and CD4
Estimation of the number of adults that need anturetroviral therapy in Moscow Region and Russia.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11808); Yurin OG, Miroshnichenko AV, Narsia RS, Deulina MO, Serebrovskaya LV, Shipulin GA, Bogoslovskaya EV, Sokolova EV, Pokrovsky VV;;;; Federal AIDS Centre, Moscow, Russian Federation; About 97% of the persons living with HIV in Moscow Region were infected on 1999 - 2003 years. Most part of them is asymptomatic now and are not under regular medical observation and number of patients that need antiretroviral therapy is unknown. Situation is the same in another regions of Rus
Once-daily (OD) regimen with NVP, 3TC, ddI or TDF in 10 patients on drug holiday: 48 weeks follow-up.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11812); Martinelli C, Fiorelli C, Giuntini R, Prieto Butille M, Ambu S, Mazzetti M, Ciuti R, Leoncini F;;;; Infectious Diseases Unit, AOU Careggi, Florence, Italy; simpler regimens with fewer daily doses and fewer pills per dose may increase adherence and treatment success. this open-label study evaluates the safety and efficacy of OD combination therapy in ART-interrupted patients receiving NVP 40
Anti - phosphomannoprotein antibodies of Candida albicans in oral candidiasis patients.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11816); Kammarnjassadakul P, Bhattarakosol P, Phanuphak P, Chindamporn A;;;; Chulalongkorn University, Bangkok, Thailand; Background : Candidiasis is a common disease among immunocompromised host, especially in HIV- infected patients. Regarding, the host defense mechanism, IgG is an immune response which plays an important role in opsonization and phagocytosis. The aim of this study was analyzed the antibody profiles against phosphomannop
Fluconazole induction mechanism in C. albicans susceptible strain in vitro.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11820); Kaocharoen S;;;; Interdepartment of Medical Microbiology, Faculty of Medicine , Chulalongkorn University, Bangkok, Thailand; The incidence of fluconazole resistance in Candida. albicans is increasing because of the over use of the antifungal drug in immunocompromised hosts especially AIDS patients. Several mechanisms of the drug resistance were reported including overexpression of efflux pump and target enzyme gene mutation. Obje
Expanding access to ARVs in Africa using a community-driven model.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11824); Nguyen VK, Fakoya A, McCarrick P, Dhaliwal M, Tiendrebeogo I, Banse H;;;; McGill University, Montreal, Canada; Over the past two years, as drug prices have dropped significant commitments have been obtained to scale up access to ARV therapy in developing countries. Community groups will be a vital element to expanding access. AAS pioneered care and treatment activities by opening the Centre Oasis in 1998 on
The Lighthouse Project: A model of integrated services for HIV/AIDS care in Lilongwe - Malawi.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11828); Phiri SJ, Nkhoma EC, Mhango E, Zumazuma B, Weigel R, Boxshall M, Neuhann F, Tauzi JW, Hosseinipour M, Thambo L, Chiunguzeni D;;;; Lighthouse Project, Lilongwe, Malawi; Innovative approach is critical to HIV/AIDS care at this time when the epidemic is causing an alarming mortality and morbidity in poor resource countries mainly in Sub-Saharan Africa. The Lighthouse provides a continuum of care to HIV/AIDS patients. The program has integrated services of Voluntary
Immune reconstitution (IR) syndrome associated with Enfuvirtide(T20) and Interleukin-2(IL2).: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11832); Nasta P, Casari S, Uccelli C, Giovanelli G, Forleo MA, Cologni G;;;; Institute of Infectious and Tropical Diseases, University of Brescia, Brescia, Italy; We report a case of Inflammatory Demyelinating Polineuropathy (IDP) with ataxia associated with a prompt immune reconstitution (IR) after use of an T20 containing salvage therapy and IL2. The hypothesis could be an aberrant IR led by a possible adverse drug reaction and amplified by the vigorous increment of T
Many HIV-infected women decline participation in an HIV care / antiretroviral program in Lusaka.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11836); Stringer EM, Wamalume C, Makuka I, Stringer JS, Degroot A, Sinkala M;;;; Center for Infectious Disease Research in Zambia, Lusaka, Zambia; Introduction: An estimated 250,000 people in Zambia are in immediate need of antiretroviral (ARV) therapy for their HIV disease. Many health care decision makers in Zambia expect demand for care to far exceed capacity. Methods: In April 2003, we implemented an ARV treatment program in one Lusaka government clinic as pa
Infections waste disposal, infection control strategies and needle stick injuries in a rural clinical setting.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11840); Thatchinamoorthy G, Ruckmani S, Jacob SM;;;; Namakkal District Headquarters Hospital, Namakkal, India; Waste disposal is not a priority in clinical settings in India . Public health authorities are yet to devise suitable strategies. In the era of HIV/AIDS needle stick injuries are a common occurrence. As a referral hospital several needle stick injuries are reported and these will be discussed. Thre
Observational study on the long term (3 years) efficacy of once a day (qd) versus twice a day (bid) simplified PI sparing HAART.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11844); Gorgolas M, Rivas P, Gil P, Estrada V, Arranz A, Goyenechea A, Garcia R, Fernandez Guerrero ML;;;; Division of Infectious Diseases/Fundacion Jimenez Diaz/Universidad Autonoma de Madrid, Madrid, Spain; PI sparing regimens are widely used in order to improve compliance. However, it is not known if regimens administered once a day are, in the long term, better than those given twice a day. Methods: Prospective, observational study of 167 patients with undetectable viral load with a PI based HAART, who switc
Challenges of integrating TB DOTS in an urban setting , at a stand-alone voluntary counseling and testing (VCT) center in Kampala, Uganda.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11848); Habineza R, Mugisha B, Namono S, Mbabazi O, Mubangizi J, Wangalwa S, Hitimana L;;;; AIDS Information Centre, Kampala, Uganda; AIDS information center (AIC) Uganda , an Organization that offers VCT and related services since 1990, started TB DOTS program in February 2003. To promote Active TB treatment adherence, clients were counseled and given an option to identify Treatment Supporter (TS). Clients were then reviewed every two we
Determinants of short and long-term adherence to antiretroviral treatment in resource- poor settings.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11852); Darder M, Michaels D, Boulle A, Ncobo N, MacLean E, Goemaere E;;;; Medecins Sans Frontieres, Cape Town, South Africa; Understanding the determinants of adherence both in the short term and for longer-term patients in resource-limited settings, is essential for effective support programmes. In this paper we explore (1) changes in self-reported adherence levels and virological outcomes over time (2) determinants of adherence, an
Early emergence of drug resistance mutations in HIV-infected children starting dual or triple therapy in Brazil.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11856); Afonso AO, Soares MA, Lambert JS, Cunha SM, Oliveira RH, Machado ES;;;; Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil; In a previous study, we have found a high prevalence of drug resistance mutations in children on dual and triple therapy for at least 96 weeks, but most of these patients were already on their second or third-line regimen. In order to assess if this high prevalence occurs in antiretroviral-naive children we
The Effectiveness of Combination Antiretroviral Regimens including the triple nucleoside backbone Tenofovir, Abacavir, and Lamivudine.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11860); Duffalo M, Gilmore J, Maniglia R, Norris A, Wolff K, Kostman J;;;; Presbyterian Medical Center, Philadelphia, United States; The triple NRTI regimen Tenofovir (TDF), Abacavir (ABC), and lamivudine ( 3TC ) has been assoc
Evaluation of Access To Care (ATC) Programme at Office of Disease Prevention and Control (ODPC) and hospitals under Ministry of Public Health, Thailand.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11864); Kongsin S, Jiamton S, Arsanam R, Tantisak B, Thanprasertsuk S;;;; Faculty of Public Health, Mahidol University, Bangkok, Thailand; The study aims to estimate compliance associated with ATC programme, to document different levels of patient monitoring and record possible factors associated with adherence. Method: Socio-economic data of 376 patients in ATC programme were collected from twelve health care facilities. Within each of the fo
Creation and Implementation of an Interdepartmental Clinic Model for the Diagnosis and Treatment of Ocular Disorders in an HIV Positive Population.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11868); Lieberman RM, Gill DA, Fischer RM;;;; Mt. Sinai Medical Center, New York, N.Y., United States; In an effort to provide quality ophthalmic care for all HIV positive patients at our center, a collaborative effort was undertaken between the Infectious Disease and Ophthalmology departments at our city hospital center. As a significant percentage of these patients develop vision-threatening disease that n
Development of a diagnostic reagent for screening of HIV1/2 antibodies in Kenya; KEMCOM.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11872); Tuei J, Omoto Y, Owino N, Kaiguri P, Mwangi A, Ngumo D, Okoth F, Oishi I, Koech D;;;; Kenya Medical Research Institute, Nairobi, Kenya; SubSaharan Africa remains the epicenter of the HIV/Aids pandemic with 28.1 million people infected. Presently, it is estimated that 2.2 million Kenyans are now living with HIV/Aids infections and 1.5 million have already died from the virus. The two types of HIV viruses, that is HIV-1 and HIV-2 are present
Opinions about delivery of HAART regimes amongst HIV-positive mothers in Nairobi, Kenya.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11876); Shankardass K, Gelmon L, Embree J, Kimani G, Kusimba J, MacDonald KS;;;; Mt Sinai Hospital, University of Toronto, Toronto, Canada; The design of highly-active antiretroviral therapy (HAART) regimes in resource-poor settings is controversial. Drugs are self-administered or during daily visits to health centres (directly observed therapy / DOT) due to concerns about adherence. The Univ. Nairobi Mother-Child Health Clinic (MCH) conducted
Issues in the clinical care for HIV+ adolescents in Brazil.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11880); Santos CE, Ramos CF, Rossi SS, Silva MA, Galbinski K, Santos VL;;;; National Program STD/AIDS - Ministry of Health, Brasilia, Brazil; Adolescence is fraught with challenges for teenagers and those involved with them. Birth rate for girls aged 15-19 yrs. increased 19 % in 1993-98. About 40 % of pregnant teens abandon school. AIDS incidence is increasing among female adolescents 13-19 yrs. old, probably because girls are having sex at an ea
Filgrastim in Georgian HIV Patients with Bacterial Infections with or without Neutropenia.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11884); Gochitashvili N, Tsertsvadze T, Sharvadze L, Gabunia F;;;; Infectious Diseases, AIDS & Clinical Immunology Research Center, Tbilisi 0160, Georgia; To assess the effect of filgrastim (G-CSF) in HIV patients with bacterial infections with or without neutropenia since it is supposed that filgrastim, together with increase of neutrophil count, can also enhance their functional activity and thus improve outcome of bacterial disease. Methods: 22 HIV infecte
A novel role of Sphingosine 1-phosphate as an enhancer of antimycobacterial activity both in vitro and in vivo.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11888); Fraziano M, Garg SK, Volpe E, Palmieri G, Mattei M, Galati D, Martino A, Piccioni MS, Valente E, Bonanno E, De Vito P, Baldini PM, Spagnoli LG, Colizzi V;;;; Dept. of Biology, University of Rome 'Tor Vergata', Rome, Italy; Innovative therapies are required for treatment of tuberculosis , in particular in association with HIV infection. To this regard, we identified a novel role of Sphingosine 1-phosphate (S1P), a polar sphingolipid metabolite, involved in a wide spectrum of biological processes (such as Ca++ mobilization, cel
Complications/side effects from two different HAART regimens in an HIV/AIDS clinic in Trinidad and Tobago.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11892); Omo-Iginomwanhia NE, Soyer-Labastide S, Telfer-Baptiste M, Cox K;;;; Medical Research Foundaiotn Trinidad and Tobago, Port of Spain, Trinidad and Tobago; Prevalence and severity of complications/ Side effects from two different HAART regimens in HIV/AIDS patients at the Medical Research Foundation of Trinidad and Tobago were studied. There are various first line antiretroviral treatment combinations given to pati
Prevalence and clinico-radiological profile of TB in HIV seropositive patients.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11896); Saini A, Bajaj L, Ranjan R;;;; Institution, Bellary, India; HIV infection has increased the burden of TB especially in populations where HIV has become common and where prevalence of TB is also common such as India . India accounts for 30% of total TB cases and 25% of TB cases with HIV coinfection in the world. This paper aims to study the prevalence,clinical and ra
Chroniic pain in distal symmetrical polyneuropathy: a qualitative investigation.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11900); Presnell S;;;; St Bartholomew's Hospital, London, United Kingdom; Distal Symmetrical Polyneuropathy [DSPN] is one of the commonest neurological manifestations of HIV disease. Chronic pain is the primary and most disabling clinical feature of DSPN, and a profile of functional impairments associated with this condition has been extensively reported. Despite the significant
The anti retroviral treatment to the Kicukiro health center /Kigali-Rwanda.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11904); Hitimana HT;;;; Anti AIDS Volunteers team in great lakes region(EVAS), Kigali, Rwanda; Objectives: -To evaluate the accessibility to the ARV treatment in Rwanda . To evaluate difficulties of the clinical and biological follow up. Method: The Kicukiro Health Center is a public hospital center that receives the biggest number of patients in Rwanda in comparison to the other Health centers in the country. P
Use of herbs among HIV-infected Thai individuals: A cross-sectional study from Thailand.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11908); Jiamton S, Kongsin S, Mahakkranukrao B, Jaffar S;;;; Siriraj Hospital, Faculty of Medicine, Mahidol University, Bangkok, Thailand; HIV infected individuals have a broad spectrum of clinical manifestations from primary HIV infection, opportunistic infections and malignancies. Use of herbs is an alternative treatment for HIV and such usage could be expensive and related to serious side effects. Knowing of prevalence and factors related t
Infant feeding practices and its effect on infants born to HIV seropositive women -Tamil Nadu, India.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11912); Radhakrishnan R, Minijacob S, Parameswari S, Rukmani R, Samuel NM;;;; PMTCT Project,Government Head quarter Hospital,Namakkal, Tamilnadu, India; HIV sero positive mothers are encouraged to exclusive breast feed for 6 months. The aim of this study is to asses the infant feeding practices among HIV seropositive mothers and to assess the mortality rates between the infants who were breast fed and infants who were on replacement feeds. Methods:80 mother
Adherence to ARV therapy: Learning from experiences of TB treatment.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11916); Chishimba S, Zulu F, Moonga HQ;;;; Commonwealth ACT, Lusaka, Zambia; Over the past decade, TB cases have increased from 100 per 100, 000 to 500 per 100, 000 in Zambia . This five-fold increase is attributed to non-drug compliance. The Multi-drug Resistance TB has emerged. Therefore, the success of ARV treatment is dependent on adherence. Adherence in the management of the ARV pr
Final analysis of a prospective, randomized, open-label, muticentre trial in naive, HIV-1-infected patients, comparing ZDV/3TC vs d4T/ddI, plus Efavirenz, Nevirapine or Indinavir/Ritonavir (AMADEUS 01 study).: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11920); Antela A, Iribarren JA, Mahillo B, Santos I, Ribera E, Gutierrez C, Esteban H, Labarga P, Gonzalez J, Andia A, Marti-Belda P;;;; H. Ramon y Cajal, Madrid, Spain; Efficacy, tolerability and genetic barrier are main issues when choosing an initial regimen. Methods: Efficacy, safety and resistance analysis in a prospective, randomized, open-label, comparative trial, in naive patients. Complete sequencing of plasma reverse transcriptase (RT) and protease (PRO) genes was
Home based care: a blessing or a curse.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11924); Mubweka D, Ochieng DS;;;; St. Mary's Hospital, Kakamega, Kenya; It has been argued that the advantages of home care override hospital care. But at times one finds oneself at cross roads. Hospitals cannot afford hospitalization of AIDS patients some of whom have only children as caregivers. Donors are shy of recurrent expenditures. The community stigmatizes and discriminates
Optimizing antiretroviral therapy in Primary HIV; a comparison of 3, vs 4 vs PI containing regimens.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11928); Fox J, Brady M, Tamm N, Fraser C, McClure M, Weber J, Fidler S;;;; Imperial College, London, United Kingdom; BackgroundThe aim of early Antiretroviral therapy (ART) in primary HIV infection (PHI) is threefold; first to limit initial plasma viraemia associated with seroconversion, Second, to limit further viral transmission. Third, to preserve the function of protective HIV-specific CD4 T-cell responses ordinarily lost and not
Characterization and quantification of the facial lipoatrophy due to HAART based on the facial lipoatrophy severity index.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11932); Arakaki D, Lima JN, Trope BM, Ramos CF, Caraciolo JM, Oyafuso LK, Serra MS, Moraes MJ, Leite OH, Pereira PC, Alves PC, Silva JC;;;; National Program STD/AIDS - Ministry of Health, Brasilia, Brazil; Due to increased survival of HIV/AIDS patients, especially after the introduction of HAART, many anatomical and/or metabolic alterations have been reported. These alterations have been denominated lipodystrophy or lipodystrophic syndrome. In Brazil , the prevalence of these alterations has been significant due
Randomization and meaning: participation in a nutritional chemoprevention trial.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11936); Moreno G, Shor-Posner G, Miguez MJ, Quintero N, Burbano X, O'Mallen S, Yovanoff P;;;; University of Oregon, Dept. of Anthropology, Eugene, United States; Adherence and retention are major challenges researchers face when conducting randomized trials. Consequently, understanding reasons for participation, is salient for successful recruitment, retention and study design. This study examined participants retention, perception, and reasons for continued partici
Treatment combination with pegylated-interferon and ribavirin in chronic hepatitis of HIV-HCV coinfected patients.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11940); Santos I, Zabaleta JP, Rodriguez-Serrano DA, Sanz J, Val FJ, Fuentes I;;;; Hospital Universitario de la Princesa, Madrid, Spain; chronic hepatitis C (CHC) is one of the most important comorbidities in HIV-infected patients and is necessary its treatment in the first phases of the disease. Combination therapy with Pegylated-Interferon (PEG) and Ribavirin (RBV) is the standard of treatment. The objective of this study is to evaluate th
Dermatological findings in HIV+ infected children before and after HAART.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11944); Munoz-Fernandez MA, Seoane ME, Bellon JM, Gurbindo MD, Resino S;;;; Hospital General Universitario 'Gregorio Maranon', Madrid, Spain; Human immunodeficiency infection result in a severe cellular immunodeficiency, what is translated in to great susceptibility to various infectious, immflamatory and malignat diseases. Skin is the most commonly affected organ in patients with HIV infection. A few studies have been associated these kinds of a
HIV infection in teenagers in St. Petersburg, Russia.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11948); Yastrebova EV, Akhtyrskaya NA, Alexandrova IV, Vinogradova EN, Rakhmanova AG;;;; City HIV / AIDS Center, St. Petersburg, Russian Federation; Background. HIV-infection has become a world wide epidemic. Taking into account that young people, aged 13-25 years, make up the greater part of drug consumers, about 30% of young people of Russia are under the threat of getting abused. According in Saint-Petersburg from 1987 to 2003 21924 HIV-positive teenagers were r
Hepatitis C surveillance at CRT DST/AIDS Sao Paulo, Brazil.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11952); Alencar WK, Tayra A, Monteiro AL, Santos NJ, Caminada S, Placco AL, Queiroz MC, Pereira HM;;;; CRT DST/AIDS, Sao Paulo, Brazil; Viral Hepatitis reporting has been mandatory in Brazil since 2000. In 2003 an epidemiological surveillance was structured more effectively at CRT DST/AIDS with active case search, aiming to know the seroprevalence of Hepatitis C in HIV positive or AIDS patients. Epidemiological characteristics of cases repo
Three year outcomes in children treated with HAART before 3 months of age in the PENTA 7 trial.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11956); Compagnucci A, Saidi Y, Harper L, Navarro ML, Girard S, Walker S, Debre M, Gibb DM, Rampon O, Schmitz T, Giaquinto C, Aboulker JP, Faye A;;;; on behalf of the PENTA steering committee. INSERM SC10, Villejuif, France; In PENTA 7 triple therapy with d4T +ddI+NFV was started in children
The psychiatric features in HIV-infected people in the national hospital of the pointG services of internal medicine and infectious diseases, Bamako - Mali.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11960); Minta DM, Coulibaly BC, Dembele MD, Sidibe AS, Takougang Moto TM, Sidibe AF, Traore HA, Koumare BK;;;; University of Bamako, Bamako, Mali; We conducted, from August 2001 to June 2001, a prospective and descriptive survey with the goal to determine the prevalence of psychiatric aspects during HIV/AIDS infection and to identify risk factors. The survey included hospitalized infected HIV patients and having benefited from a psychiatric consultation before an
Ethiopian Red Cross Society community based home care and support.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11964); Teferi MT;;;; Ethiopian Red Cross Society, Addis Ababa, Ethiopia; The Ethiopian Red Cross Society works to reduce the ever-increasing burden on the public health system due to HIV/AIDS related illnesses through developed community based social care & support. ERCS HBC activities include training youths and community volunteers as care providers & supporters for the terminally
A holistic approach to pediatric HIV/AIDS: an experience from Uganda, East Africa.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11968); Banura P, Dunigan NP, Johnson GA, Nakandi L;;;; NGO, Masaka, Uganda; Provision of adequate healthcare and good nutrition play major roles in the management of HIV/AIDS in children. In Africa, in general, and particularly in Masaka, malnutrition and childhood infections constitute major health problems. The situation is made even worse when these children are orphaned as result o
Antiretroviral treatment adverse reactions in multiexperienced horizontally HIV-infected patients.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11972); Dumitrescu F, Chiurtu A, Giubelan L, Cupsa A, Poajga T;;;; University of Medicine and Pharmacy, Craiova, Romania; The introduction of antiretroviral therapy (ARVT) has reduced AIDS-related morbidity and mortality but also has led to registration of toxic effects. To evaluate the incidence and spectrum of medium and long term adverse reactions (AR) in multiexperienced HIV/AIDS patients. Material and method: R
Patients with HCV/HIV co-infection achieving a sustained virological response following HCV treatment with peginterferon alfa-2a (Pegasys^®) plus ribavirin (Copegus^®) have improved health related quality of life.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11976); Dieterich DT, Rodriguez-Torres M, Rockstroh JK, Lissen E, Gonzalez-Garcia J, Lazzarin A, Carosi G, Sasadeusz J, Katlama C, Montaner J, Sette H, Wintfeld N, Green J, Patel KK, Torriani FJ;;;; Mt. Sinai School of Medicine , New York, NY, United States; Introduction: In patients with HCV mono-infection, sustained virological response (SVR) is associated with improved health-related quality of life (HRQOL). However, the relationship between SVR and HRQOL in patients with HCV/HIV coinfection is not known. Methods: HRQOL was measured in a phase III study (n=860) evaluati
Hepatic mitochondrial toxicity of nucleoside reverse transcriptase inhibitors.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11980); Spiridon G;;;; Hopital Cochin, Paris, France; Background Acute lactic acidosis is the hallmark of mitochondrial(mit) toxicity during long term treatment(trt) of HIV+ patients(pt) with NRTI. However, potential hepatic toxicity of mit damage under these prolonged trt is partly unknown. Pt and methods: Six HIV+ pt (47+/-5,6 years) with chronic abnormal liver tests af
Field test of guidelines for nutritional management in pediatric HIV infection.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11984); McKeen B, Romeyn MA, Fields-Gardner C, Bowers M, Bradley A;;;; Andrew Ziegler Foundation, San Francisco, CA, United States; Guidelines for nutritional management of HIV-infected pediatric patients were field tested through two pediatric clinics (San Antonio and Harlingen, Texas). Methods: Children were referred for enrollment in the field test by their primary physician. A nutrition program based on guidelines included counselin
Adherence to highly active antiretroviral therapy (HAART) for management of HIV Kaposi's sarcoma (KS) - South Africa.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11988); Bodasing U, Coovadia HM, Mosam A, Friedland GH;;;; Nelson R Mandela School of Medicine, Durban, South Africa; Few studies have been published relating to medication adherence to antiretroviral (ARV) treatment in resource-poor settings. This study aimed to evaluate adherence to HAART in Kwa-Zulu Natal in the context of a clinical trial of ARVs for KS. The objectives were to determine levels and consistency of adhere
Development of a highly sensitive reverse transcriptase assay using real time PCR.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11992); Thtithanyanont A, Sakulpongyoenyong T, Orathaiwan P;;;; Mahidol University, Bangkok, Thailand; A highly sensitive reverse transcriptase ( RT) assay was developed by modifying a previously reported polymerase chain reaction ( PCR) based reverse transcriptase (RT) assay. A new approach was designed to eliminate the need for post PCR manipulation. Methods: An in vitro transcribed heteropolymeric RNA seq
Concurrent use of bupropion with cytochrome p450 inhibitors: no outstanding clinical interactions.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B11996); Pedrol E, Ribell M, Vidal I, Garcia P, Deig E, Soler A;;;; Hospital General de Granollers, Granollers, Spain; Metabolic abnormalities due to antiretroviral therapy(AT) provide grounds for concern about an eventual increase in cardiovascular disease, that could be higher if we join currently smoking habit. Bupropion (B) is one of the most effective treatment for smokers who are trying to stop smoking. Like most of the AT, B s m
Efficacy and safety of Indinavir/Ritonavir 400/100 mg BID in antiretroviral therapy-naive Thai AIDS patients: a 48-week result.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12000); Mootsikapun P, Chetchotisakd P, Anunnatsiri S, Bunyaprawit P, Horsakulthai M;;;; Department of Medicine, Khon Kaen University, Khon Kaen, Thailand; To evaluate efficacy and safety of indinavir / ritonavir 400/100 mg twice daily plus d4T and 3TC in antir
Changes in prevalence of genotypic resistance in chronically infected antiretroviral-naive HIV patients in houtson: 1999 and 2003.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12004); McCormack OE, Arduino RC, Barnett BJ;;;; University of Texas- Houston, Houston, United States; Resistance mutations were found in 11% of 44 chronically infected patients in Houston, TX, from June to September 1999. The purpose of this study is to determine the change in prevalence of resistance mutations in the same patient population from 1999 to 2003. Methods: Genotypic resistance testing (TRUGENE,
Analysis of the impact of socio-economic factors on adherence to ARVs in a cohort of patients subsidised by ESTHER programme at the Central Hospital in Kigali, Rwanda.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12008); Mukabutera A, Nzabandora J, Mugabo J, Omes C, Goedertz H, Dushimiyimana D, Arendt V;;;; Centre Hospitalo-universitaire de Kigali, Kigali, Rwanda; Concerns have been raised about adherence to antiretroviral (ARV) therapy in indigent patient populations. The aim of this study was to analyse the impact of socio-economic factors on adherence to ARV in a cohort of patients subsidised by ESTHER programme at the Central Hospital in Kigali, R
The use of directly observed therapy (DOT) among hard-to-reach individuals receiving highly active antiretroviral therapy (HAART).: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12012); Mitty JA, Macalino GE, Loewenthal HG, Bazerman LB, Sanford S, MacLeod C, Flanigan TP;;;; The Miriam Hospital/Brown University, Providence, United States; The principle of DOT has its roots in the treatment of tuberculosis (TB). There are similarities between HIV and TB, such as the populations they affect and concerns about the development of drug resistance. As such, DOT may be beneficial to certain HIV+ individuals who have difficulty adhering to HAART. Me
Prevalence of HCV and HBV in HIV positive patients attending a general hospital in Buenos Aires, Argentina.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12016); Fuse V, Cornelio CI, Meraldi N;;;; Hospital Pirovano, Buenos Aires, Argentina; HIV coinfection with hepatitis C virus (HCV) or/and hepatitis B virus(HBV) is a growing public health concern. As these viruses share the ways of transmission, many people are coinfected or even have the three infections.
Efficacy, safety, adherence and pharmacokinetics of the simplification to a once daily regimen with NNRTIs in patients previously receiving antiretroviral therapy twice daily.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12020); Casado JL, Moya J, Marin A, Aranzabal L, Moreno A, Antela A, Dronda F, Perez-Elias MJ, Moreno S;;;; Ramon y Cajal Hospital, Madrid, Spain; Background : The dosification once daily (QD) of antiretroviral therapies could improve adherence and quality of life in HIV-infected patients. However, few studies have shown the efficacy, safety, and adherence of a QD regimen in patients already receiving a low number of pills twice daily (BID). Methods : Prospective
Immunological effects of combined treatment with Mycophenolate Mofetil and HAART in acute and chronic HIV-1 infected, treatment naive patients.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12024); Vrisekoop N, Sankatsing SU, Jansen CA, Roos MT, Otto SA, Schuitemaker H, Lange JM, Prins JM, Miedema F;;;; Sanquin Research Landsteiner Lab and Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands; The immunosuppressant Mycophenolate Mofetil (MMF) is a prodrug of mycophenolic acid (MPA), a selective and reversible inhibitor of de novo synthesis of the purine guanosine in lymphocytes. MMF has been proposed for HIV therapy, since it is expected to prevent HIV replication and to decrease the HIV cellular
A randomized study to assess the clinical impact of a multidisciplinary approach to sustain adherence to antiretroviral therapy (Intesa). Study design and preliminary results.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12028); Orofino GC, Leombruni P, Carosella S, Bolgiani M, Lavagnino L, Guastavigna M, Pagano E, Scrignoli S, Talarico R;;;; Amedeo di Savoia Hospital, Division A Infectious Diseases, Turin, Italy; Adherence is one of the most important factors influencing an effective antiretroviral therapy. Since 2000 our service has implemented a multidisciplinary program aimed to support non adherent patients. A randomized study to evaluate the clinical impact of such approach has now been started. Methods: The st
Correlates of prolonged breastfeeding among HIV-1 infected women.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12032); Wariua WG, Wamalwa D, Mbori-Ngacha D, Obimbo E, Otieno P, Farquhar C, Gichuhi C, Bosire R, John-Stewart G;;;; University of Nairobi, Nairobi, Kenya; Objectives: To determine the correlates of prolonged breast feeding (beyond seven months) among HIV-1 infected women. Methods: The study was conducted in an outpatient clinic in Kenyatta National Hospital, Kenya between 1999 and 2002. Women were enrolled during pregnancy and sociodemographic information collected. For
Highly active antiretroviral therapy (HAART) in pregnant HIV-infected women. Efficacy and safety for the mothers and infants.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12036); Vandercam B, Dupont M, Abarzua F, Van Wijngaarden E, Hubinont C, Bernard P, Goubau P, Brichard B;;;; Saint-Luc University Hospital, Brussels, Belgium; The use of antiretroviral therapy has reduced mother-to-child transmission (MCT) of HIV. However, this benefit is associated with the risk of in utero and neonatal drug exposure. Methods: Observational retrospective study (jan 1999 - dec 2003) of pregnant women receiving HAART. General characteristics, evol
Disseminated melioidosis in an HIV-infected patient.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12040); Riengchan P, Suankratay C, Kulwichit W, Hanvanich M;;;; Faculty of Medicine/Chulalongkorn University, Bangkok, Thailand; Thailand has a high prevalence of HIV-infected population. It is estimated that 1.0-1.5% of 65 million population are HIV seropositive. Melioidosis is an endemic tropical disease, especially in the Northeastern part where the disease occurs 4.4 per 100,000 per year (Suputtamongkol Y, 1994). But there has be
Efficacy of PMTCT services in a routine care setting.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12044); Nduati RW, Mbori-Ngacha D, Kalibala S, Ogola S, Oyieke J, Nyamongo G, Scott G, Muthami L, Rutenberg N;;;; University of Nairobi and NARESA, Nairobi, Kenya; Background : There is limited information on whether PMTCT services integrated into existing health services impact the prevalence of HIV infection among young infants. Objectives: To determine the impact of integrating PMTCT on prevalence of HIV infection among 6-week old infants. Methods : The PMTCT services that inc
Report of a patient with anal ulcer and granulomatous hepatitis.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12052); Mansouri SD, Tabarsi P, Mirsaeidi SM, Amiri M, Alaei A, Farnia P, Abbasi A, Mohammadi F;;;; National Research Institute of tuberculosis and Lung Diseases, Tehran, Islamic Republic of Iran; INTRODUCTION: Anal and perianal tuberculosis is a rare manifestation of TB. Anal ulcer and fissure in an unusual location which is slow to heal should have biopsy performed, with appropriate stains and cultures to rule out tuberculous disease. METHOD AND RESULT: In this case report we introduce one HIV patient who pres
Successful therapy of tuberculous spondylitis in an HIV-patient caused by multi-drug resistant mycobacterium bovis.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12056); Feldt T, Leidel R, Oette M, Goebels K, Bode J, Erhardt A, Haeussinger D;;;; Heinrich Heine University, Duesseldorf, Germany; Multi-drug resistant tuberculosis (MDRTB) is an emerging threat especially among HIV-infected persons and associated with poor prognosis. We report a case of successful therapy of tuberculous spondylitis caused by highly resistent Mycobacterium bovis. Case report: A 34 year old, Laotian patient with HIV-Inf
Factors associated to adherence among patients initiating antiretroviral (ARV) therapy, Belo Horizonte, Brazil, 2001-2003.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12060); Bonolo PF, Cesar CC, Acurcio FA, Ceccato MG, Menezes-Padua C, Alvares J, Campos LN, Guimaraes MD;;;; Department of Preventive and Social Medicine, School of Medicine, Federal University of Minas Gerais, Belo Horizonte, Brazil; Adherence to ARV is essential to maintain long term viral supression at optimal levels as indicated by data from North America and Europe. However, there are few studies which have assessed adherence among patients initiating treatment in countries such as Brazil , where HAART is widely available. Methods:
Randomized feasibility study of a cell phone and a pager as potential adherence enhancing devices.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12064); Andrade A, Wu AW, Skolasky RL, McCue C, Celano S, Austin A, Barnes A, Mancini C, McArthur J;;;; The JOhns Hopkins University, Baltimore, United States; Electronic devices that provide frequent reminders may improve adherence to HAART. We conducted a feasibility study to evaluate a cell phone and apager-based medication reminder for patients infected with HIV on HAART. Methods: 20 patients on HAART were randomized to receive either a cell phone (AT&T Wi
False-positive HIV serological tests in acute malaria patients in Ethiopia.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12068); Kassa D, Petros B, Mesele T, Tilahun T, Mekonnen T, Meless H, Wolday D;;;; EHNRI, Addis Ababa, Ethiopia; We were assessing the possible association of malaria and HIV infections at Wonji Sugar Estate. Methods: Malaria parasites were detected using light Midroscopy. Anti-HIV antibodies were tested using rapid tests, HIV spot and Determine HIV-1/2. Seropositive results were confirmed by
Gemfribozid and omega 3 unsaturated fatty acids in HAART related hyperlipemia.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12072); Santoro D, Mauri MR, Sala E, Rinaldi E, Giana G;;;; Infectious dieseases Department S.Anna Hospital, Como, Italy; A large number of patients using a protease inhibitors based therapy develops hyperlipemia. Drugs can be used to reduce serum lipid levels: we evaluate, by an observational-longitudinal study, an innovative drugs association between Gemfibrozid and Omega 3 unsaturated fatty acids in a group of 8 patients in
Lipid abnormalities in HIV-infected patients are not correlated with lopinavir plasma concentrations.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12076); Torti C, Quiros-Roldan E, Regazzi-Bonora M, De Luca A, Lo Caputo S, Patroni A, Micheli V, Carosi G; Institute of Infectious and Tropical Diseases, University of Brescia, Brescia, Italy; Lopinavir/ ritonavir (LPV/r) use is associated with increase in triglycerides (TG) and/or cholesterol (CHOL) levels. Higher LPV concentrations have been associated with higher risk of total CHOL and/or TG elevations. We aimed at investigating whether lipid changes are associated with LPV plasma concentratio
Detection of divergent mutation patterns in cloned sequences of the HIV-1 reverse transcriptase and protease genes in HIV-1 positive patients under HAART.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12080); Dennin RH, Zhu H, Dalhoff K, Rupp J;;;; Institute of Medical Microbiology and Hygiene, University of Luebeck, Luebeck, Germany; Antiretroviral drug resistance is one of the major factors of therapeutic failure in HIV-infected patients. Resistance testing is recommended to guide treatment decisions. Sequence analysis in genotype resistance testing implies the mutations representing a homologous virus population. However, superposed m
A peer counseling intervention for rural women with HIV.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12084); Phillips KD, Moneyham L, Murdaugh C, Boyd M;;;; University of South Carolina - College of Nursing, Columbia, South Carolina, United States; In the United States , rural women with HIV/AIDS have limited access to available resources such as peer support. The purpose was to test the effectiveness of a peer-counseling intervention for rural women with HIV/AIDS. Methods: The 3-year study used a longitudinal, quasi-experimental design with repeated
HIV-1 resistance testing during pregnancy: Prevalence of mutations and analysis of mother-to-infant transmission.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12088); Liuzzi G, Liuzzi G, Di Giambenedetto S, Forbici F, Bagarelli A, Sette P, Visconti E, Zaccarelli M, Pastore Celentano L, Tozzi V, Zinzi D, Anzidei G, Cauda R, De Luca A, Tamburrini E, Perno CF, Antinori A, Cingolani A;;;; INMI L. Spallanzani IRCCS, Roma, Italy; Background. Aims: 1. To determine prevalence of genotypic resistance to antiretrovirals among pregnant women. 2. To analyze the occurrence of mother-to-infant transmission (m-t-i). 3. To evaluate viro-immunologic and genotypic f-u. Methods. Data of all HIV+ pregnant women with genotype resistance test (GRT) (1.1999-12.
Aderance to antiretroviral therapy in HIV infection - risk factors for interupting the medication in Giurgiu county.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12091); Manolescu L, Marinescu P;;;; Carol Davila, University of Medicine, Bucharest, Romania; To evaluate the degree of aderence to antiretroviral treatment at the HIV infected children under treatment from Giurgiu. METHODES: We analysed 99 children HIV infected from the day clinic Trei frati patati Giurgiu county, Romania .62% of the children were born in1988 and the rest (38%) in 1989. We evaluated
Coping with irregular ARV supplies: PLHA experience in Nigeria.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12095); Ojimba AO, Okonkwo IP, Onyeonoro U;;;; NAUTH, Nnewi, Nigeria; Nigeria initiated a pilot ARV treatment program in 2002 in 25 federal medical institutions to provide ART to 10,000 PLHAs. However the drug supply had become so irregular that in the last 2 months, they have become unavailable. This paper describes coping mechanisms adopted by PLHAs benefiting from the prog
Semiquantitative measurements of CD4 and CD8 surface expression on circulating T-Lymphocytes of HIV-infected patients using flow cytometry technique routinely used for monitoring cell counts.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12099); Oliveira CA, Ribeiro TZ, Salgado MM, Ueda M; Adolfo Lutz Institute-Sao Paulo State Secretariat of Health, Sao Paulo, Brazil; Flow cytometry (FC) tools have been used widely to assess surface markers on circulating blood cells. To evaluate the profiles of CD4/CD8 expression on T-lymphocytes (Tly) from HIV-positive and negative subjects, we analyzed acquisition data from FC immunophenotyping routine. Methods: We anonymously evaluat
Resistance in antiretroviral therapy.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12103); Slim J, Finkel DG, Chun DJ, Smith SM;;;; Saint Michael's Medical Center, Newark, United States; Introduction: Increasing HIV resistance to antiretroviral (ART) therapy is becoming a serious problem in countries were the use of those medication is widespread. Some experts have suggested an initial therapy with boosted Protease Inhibitor (PI); as opposed to initial therapy with a Non-Nuceloside Reverse transcriptas
Prevalence of cross-resistance genotypes in treatment-experienced patients.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12107); Rodes B, Garcia F, Gutierrez C, Martinez-Picado J, Aguilera A, Saumoy M, Vallejo A, Domingo P, Dalmau D, Riera M, Blanco JL, Pedreira J, de Mendoza C, Perez-Elias MJ, Vidal F, Leal M, Soriano V;;;; Hospital Carlos III, Madrid, Spain; The number of HIV-1-infected patients with a history of multiple treatment failures is increasing overtime. The therapy success in these patients is often compromised by the presence of multi-drug resistant viruses. We assessed the rate of genotypes causing broad cross-resistance to NRTI, NNRTI and PI in pa
Lopinavir pharmacokinetic variability in a population of heavily treated patients.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12111); Torti C, Quiros-Roldan E, Di Giambenedetto S, Regazzi-Bonora M, Pierotti P, Orani A, Cargnel A, Cologni G, Carosi G; Institute of Infectious and Tropical Diseases,University of Brescia, Brescia, Italy; Increased LPV exposure obtained in vivo through combination with low dose ritonavir (r) may help to overcome a certain grade of resistance but not all. It is important to know what factors could affect LPV levels. We aimed at analizing LPV variability and possible risk factors for its decreased levels.
Diversity and prevalence of genotypic resistance mutations in HIV-1 infected children in Sao Paulo, Brazil.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12115); Almeida FJ, Berezin EN, Rodrigues R, Santos AG, Silva FF, Safadi MA, Brigido LF;;;; Santa Casa de Sao Paulo, Sao Paulo, Brazil; Introduction: HIV-1 profile of resistance mutations is not well known in children in Brazil , especially in ARV naive patients. Many factors may contribute to the emergence of resistance in this population. Methods: We evaluated a group of naive children at the diagnosis and a group of treated children failing ARV regi
Pre-test counselling or information giving session in MTCT.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12119); Ramachandran R;;;; South India AIDS Action Programme (Siaap), Chennai, India; During pre-test counselling for PPTCT at ante-natal clinics in Tamilnadu, only information is given but fears, options and support systems are not explored. Many positive women report non-acceptance by husbands and discrimination in the family. One counsellor available 4hours daily deals with over 150women.
Maternofetal transmission of HIV: analysis of 97 pregnant women followed by the Rio de Janeiro State University Hospital Pedro Ernesto( Hupe).: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12123); Gomes VR, Lima DB, Magalhaes GA, Stanzsbock DC, Ventura DG, Cabral AC;;;; State University Of Rio de Janeiro, Hospital Pedro Ernesto, Rio de Janeiro, Brazil; INTRODUCTION: HIV vertical transmission represents around 98% of pediatric HIV cases in Brazil . OBJETIVES: We intend with this work to form a multiprofessional staff to assist pregnant women and newborns, in the sense of creating preventive measures to fight HIV vertical transmissionMETHODS: HIV positive pregnant wome
Incorporeting patients' suggestions in individualized intervention program for improving adherence to antiretovirals.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12127); Ammassari A, Trotta MP, Marconi P, Murri R, Cozzi-Lepri A, Melzi S, Zaccarelli M, De Longis P, Bontempo G, Ladisa N, Sighinolfi L, Castelli F, Madeddu G, Abrescia N, Lichtner M, Vecchiet J, Orofino GC, d'Arminio Monforte A, Antinori A;;;; Istituto di Clinica delle Malattie Infettive, Universita Cattolica del S. Cuore, Roma, Italy; We evaluated usefulness of an individualized intervention based on physicians knowledge about patients Adh level and their suggestions to improve Adh. Methods: Prospective multicenter cohort study. Adh was assessed by a self-reported questionnaire. Patients were also asked to suggest the most needed interve
Efficacy and tolerance of the combination of d4t plus ddI plus efavirenz as initial therapy in HIV-infected patients.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12131); Carton JA, De la Torre J, Perez E, Gomez F, Camba M, Arranz A, Torres R, Echevarria S, Blanch J, Geijo P, Alvarez C;;;; Nuestra Senora de Covadonga, Oviedo, Spain; Background : The combination of d4T , ddI and efavirenz could offer a great antiviral potency and a high genetic barrier. However, concern exists about the incidence of adverse events, mainly neuropathy or pancreatitis. Methods : Prospective, multicenter study of 464
Long-term efficacy after switch from protease inhibitor (PI)-containing HAART to abacavir, lamivudine, and zidovudine.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12135); Opravil M, Baumann D, Chave JP, Furrer H, Calmy A, Bernasconi E, Blasko M, Vernazza P, Ledergerber B, Perrin L;;;; Swiss HIV Cohort Study, University Hospital, Lausanne, Switzerland, University Hospital, Zurich, Switzerland; Switching patients from an effective PI-containing HAART to abacavir , lamivudine, and zidovudine ( Trizivir ) maintains viral suppression if patients do not harbor archived resistance mutations against NRTIs. However, the long-term efficacy of this approac
A randomized triple-blind placebo controlled trial of amoxicillin for treatment of acute bronchitis in HIV-1 infected and uninfected adults in Nairobi, Kenya.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12139); Nduba V, Mwachari CW, Meier A, Park D, Cohen CR;;;; Kenya Medical Research Institute, Nairobi, Kenya; Acute respiratory tract infection (RTI) is the most common presentation to outpatient clinics in HIV-1 infected and uninfected adults in sub-Saharan Africa, with antibiotics prescribed for 50% to 90% of cases. We performed a randomized placebo controlled trial to determine whether treatment with amoxicillin
Risk factors in HIV-HBV co-infection.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12143); Manolescu L, Marinescu P;;;; 'Carol Davila', University of medicine, Bucharest, Bucharest, Romania; To evaluate the degree of hepatotoxicity and the risk factors for the elevation of the hepatic enzymes in HIV-HBV co-infected children durind antiretroviral treatment. METHODES: During the first 6 month from the terapy change the hepatic enzymes were monitorized at 29 children HIV-HBV co-infected (median age
Challenges in implementing programs for prevention of mother to child transmission of HIV in Kinshasa, DRC.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12147); Matendo R, Behets F, Vanderfaeillie A, Nanlele D, Kilese N, Callens S, Lepira F, Van Rie A, Vaz LM;;;; UNC-DRC, Kinshasa, Congo; The implementation of programs to prevent transmission of HIV infection from mother to child (PMTCT) requires a functioning basic antenatal care (ANC) system. Methods: We evaluated existing ANC in 18 health centers in Kinshasa, DRC prior to scaling up of PMTCT. Using surveys, interviews and onsite observati
The risk of infectious morbidity among infants born to HIV infected mothers following preterm spontaneous rupture of the membranes and expectant management.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12151); Barclift S, Ross BJ, Fox H, Keller J, Anderson J;;;; Johns Hopkins Hospital, Baltimore, United States; Spontaneous rupture of the membranes prior to 37 weeks gestation (pPROM) is an obstetrical dilemma that is associated with increased neonatal morbidity and mortality. Appropriate management is debatable and varies with gestational age, near term vs. remote from term, these patients are frequently treated co
Results of an open multicenter cohort study of perinataly exposed children to antiretrovirals in Spain.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12155); Almeda J, Sanchez E, Fortuny C, Rojano X, Solis I, Ramos JT, Rodrigo C, Mur A, Bertran JM, Casellas M, Coll O, Grane N, Guillen S, Gonzalez-Tome MI, Casabona J; CEESCAT. Hospital Universitari Germans Trias i Pujol, Badalona, Spain; Antiretrovirals (ARV) during pregnancy have demonstrated to be effective as prophylaxis for mother-to-child HIV transmission. However, the ARV drugs used are in groups B or C of the FDA classification and may cause toxicity in both mothers & children. The objective of this study is to determine effectiv
The Effectiveness of PWHA Peer support group to improve adherence to ART in resource poor settings ~ Collaboration program among 'SHARE', an NGO on health, the PWHA group and Community Hospital in the rural area of Thailand ~.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12159); Lee S, Ashida T, Moontha S, Asasri S;;;; SHARE,NGO, Ubon Ratchathani, Thailand; Introduction of the nationwide ART program in Thailand requires extraordinary efforts for the concerned especially in northeastern region, the nation s poorest area and furnishing the insufficient support system for and among PWHA. SHARE has been generating the holistic approach that PWHA peer supp
Evaluation of switching from stavudine (d4T) to tenofovir DF (TDF) among patients receiving HAART with non-detectable HIV RNA measurements and d4T-associated toxicities.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12163); Sterman FL, Orr A, Flaherty J, Lundy S;;;; Pacific Horizon Medical Group, San Francisco, United States; D4T is frequently prescribed, but is associated with many short and long-term toxicities. Limited data exist regarding patient outcomes after switching virologically suppressed patients from D4T to other NRTIs such as TDF, which have demonstrated better safety profiles. We conducted a retrospective analysis
Knowledge and perceptions of antenatal women towards prevention of mother to child transmission of HIV.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12167); Muula AS, Misiri HE;;;; Department of Community Health, College of Medicine, Blantyre, Malawi; To determine antenatal women attendees knowledge and perceptions towards prevention of mother to child transmission of HIV in Blantyre District, Malawi . Methods: Cross sectional qualitative study utilizing focus group discussions (FGDs). Discussions were recorded on audio tape and later transcribed. Analys
Poor penetration of lopinavir in the genital tract of men receiving HAART in Brazil.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12171); Barroso PF, Vergara TR, Schechter M, Suarez-Kurtz G, Estrela RC, Cerbino-Neto J;;;; HUCFF-Universidade Federal do Rio de Janeiro, Rio De Janeiro, Brazil; Poor penetration of antiretrovirals into the genital compartment may allow the evolution of resistant mutants that can then be transported into blood, and thus accelerating virologic failure and reducing the durability of HAART. Objectives: To evaluate lopinavir levels in semen and blood of a group of m
How suitable is the flow chart used in the diagnosis of urethritis in Kenya?: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12175); Kariuki MW, Ngugi E, Ferguson A, Njagi E, Thottingal P;;;; University of Nairobi, Department of Comminty Health, Nairobi, Kenya; The incidence of urethritis among male patients attending City Council health clinics in Nairobi is said to be high, although the clinics have a shortage of staff and lack the necessary diagnostic materials. The unavailable resources have necessitated the use of syndromic flow charts in the diagnosis and ma
A programme of support around disclosure of diagnosis to children with HIV.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12179); Donaghy S, Waugh S;;;; St George's Hospital, London, United Kingdom; It is generally accepted that children have a right to know about their illness and be involved in their care. However, when a child has HIV there are many complex issues that make carers very cautious about giving their child information. Carers often feel anxious and overwhelmed by the thought of talking to t
Utlizing the unique skills of Nurse Practitioners in the delivery of HIV Care and Support: A Model to Emulate.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12183); Santhanam H;;;; Anjali Consulting Services, Yorktown Heights, New York, United States; To those working in the field of HIV/AIDS, statistics on the staggering numbers of people infected with HIV are well known and often lamented. Currently, only 8% of estimated 6 million who need Antiretroviral Therapy (ART) in developing countries are receiving it. In response to this situation, the
HIV medicine and HAART in community hospitals in Northern Thailand.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12187); Jourdain G, Fregonese F, Kanabkaew C, Pattanapornpan N, Peongjakta R, Kanjanavanit S, Thanasri S, Cowatcharagul W, Sirijittrakorn P, Ngo-Giang-Huong N, Lallemant M;;;; Harvard School of Public Health & PHPT-IRD054, Chiang Mai, Thailand; In northern Thailand , community hospitals are facing multiple challenges in the management of a large number of HIV infected patients. Describe the first six months events and outcome in patients on antiretroviral therapy (ARV) in a pilot program supported by Oxfam. Methods: Available data, pros
Utilization and cost of two HIV delivery health models in Bogota, Colombia.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12191); Burbano X, Rojas P, Pons M, McCallister K, Miguez-Burbano MJ, Shor-Posner G;;;; Fundacion Santa Fe de Bogota, Bogota, Colombia; Health Services Providers have designed different delivery models to provide coverage for HIV infected patients. These models need to be carefully evaluated in order to determine the most advantageous and cost effective methods of HIV care, especially in resource-poor settings. Methods: The present study co
Alteration of cerebral metabolism in the basal ganglia of HIV-infected adults assessed by phosphorus magnetic resonance spectroscopic imaging.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12195); Zsemberyne Kovacs E, Bush BA, Chu WJ, Netson KL, Shelton BJ, den Hollander JA, Benos DJ;;;; Department of Physiology and Biophysics, University of Alabama at Birmingham (UAB), Birmingham, United States; The pathological processes occurring in the basal ganglia play a pivotal role in the development of AIDS Dementia Complex (ADC). We performed phosphorous magnetic resonance spectroscopic imaging ([3][1]P-MRSI) on 16 HIV+ and 20 HIV- (control) subjects to investigate the changes in the [3][1]P metabolite lev
Assistance to advanced stage AIDS patients in West Africa: the experience of the Centre d'Accueil et de Solidarite de Ouagadougou (CASO), Burkina Faso.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12199); Carosi G, Castaldo E, Pietra V, Pignatelli S, Simpore J, Rouamba S, Luise V, Pizzocolo C, Castelli F;;;; Centre d'Accueil et de Solidarite de Ouagadougou, Ouagadougou, Burkina Faso; Burkina Faso is a sahelian West-African Country where HIV seroprevalence, mainly HIV-1, is 7-10% in adult population. Most HIV patients still do not benefit from HAART leading to an increasing number of advanced stage patients, who do not have acces to hospital care. The Centre d Accueil et de Solidarite de
Optimisation and evaluation of the Dynabeads technique in light microscopy allowing CD4+ T lymphocyte numeration for HIV infected people in resource-limited countries.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12203); Diagbouga SD;;;; Centre Muraz, Bobo-Dioulaso, Burkina Faso; To study several staining methods allowing an optimal counting of CD4+ T lymphocytes (T4) in light microscopy, for the Dynal T4 Quant. Kit (Dynabeads technique). To compare the Dynabeads technique using quantification procedures for T4 in light microscopy with: (1) the Dynabeads technique using quantificati
Influence of the frequency in the medication collection on adherence to antiretroviral therapy of HIV+ patients.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12207); Munoz-Moreno JA, Fumaz CR, Ferrer MJ, Tuldra A, Andreu A, Bonafont X, Clotet B;;;; Lluita contra la Sida Fdn. HIV Unit. Germans Trias I Pujol Univ. Hosp., Barcelona, Spain; Little is known about the relation between frequency in collecting antiretroviral medication (MED) and adherence (ADH) to treatment. It has been affirmed that collecting MED with a minor frequency might have a negative impact on ADH. On the other hand, the fact of picking up MED less frequently might cause
The PMTCT uptake in 10 Kenyan hospitals: The experience of Kenya AIDS NGOS Consortium (KANCO).: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12211); Ragi AG, Kilonzo H, Kimani JN;;;; Kenya AIDS NGOs Consortium, Nairobi, Kenya; HIV/AIDS is a major concern in Kenya . Most pregnant mothers do not know of their HIV status even when they are pregnant. Children whose lives could have been saved get infected during birth or after birth from their mothers. With prevalence rate of 10% this has had a devastating impact in the country s develop
Can videx EC (ddi) be taken withe food and maintain virologic suppression? A retrospective reveiw of patients who admit to taking their ddi with food.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12215); Johnson DL;;;; Daniel V Lara HIV Clinic, AltaMed Health Services, Los Angeles, United States; The primary objective of this study was to assess long-term viologic suppression in patients taking ddI with food. Abstract: A patient s adherence to combination therapy is a critical component of successful treatment outcomes and although they are educated about dosing, many take their ARV when
Measures and patterns of adherence to antiretroviral therapy - insight from Medication Event Monitoring System (MEMS) data.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12219); Anderson RM, Ghani AC, Chapman R, Vernazza P, Lapins D, Mayer SL;;;; Imperial College London, London, United Kingdom; Adherence to antiretroviral (ARV) therapy is a significant predictor of treatment success. We use MEMS data to identify different adherence patterns and measures that best reflect variability in overall adherence patterns. Methods: MEMS data (for protease inhibitors ) collected from 202 HIV-infected men
Assessment of adherence to antiretroviral therapy in HIV-infected South African adults.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12223); Brown S, Friedland GH, Bodasing U;;;; Brown Medical School, Providence, United States; There has been very little systematic examination of adherence to HAART among HIV-infected patients in resource-limited settings. This study sought to examine self-reported adherence to HAART, the impact of adherence on biologic outcomes, and the determinants mediating non-adherence for HIV-infected adult pa
Seroprevalence of HHV8 in HIV infected pregnant women in Thailand.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12227); Sirirungsi W, Ngo-Giang-Huong N, Chanthubthong P, Preedam P, Kanjanasing A, Limtrakul A, Sakondhavat C, Langkafa D, Surawongsin S, Pornkitprasarn W, Wannapira W, Potchalongsin S, Lallemant MJ;;;; Chiang Mai University, Chiang Mai, Thailand; Knowledge of HHV8 seroepidemiology is critical for the study of its pathogenesis. In Thailand , the prevalence of Human Herpes type 8 (HHV8) IgG antibodies in HIV infected pregnant women and the impact of maternal HHV8 and HIV co-infection on transmission of HIV to their babies have not been studied. Method
Discontinuation of HAART: predictive value of and impact on immunological changes.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12231); Touloumi G, Pantazis N, Stirnadel HA, Porter K;;;; Athens University Medical School, Athens, Greece; To characterise predictors of HAART discontinuation (TD), describe immunological changes during TD and investigate risk factors for CD4 decline following TD. Methods: The study population was derived from the CASCADE, a multi-cohort HIV observational database of 8300 persons with well documented times of HI
Low T Cell surface CCR5 density is not an adverse host factor in chronic hepatitis C : implications for the therapeutic use of CCR5 antagonists in HCV/HIV co-infected subjects.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12235); Corbeau P, Vincent T, Portales P, Baillat V, Merle de Boever C, Le Moing V, Vidal M, Ducos J, Clot J, Reynes J;;;; Laboratoire d'Immunologie, Hopital Saint Eloi, Montpellier, France; CCR5 antagonists represent promising anti-HIV agents. Yet, if the CCR5 chemokine receptor plays a positive role in Hepatitis C Virus (HCV) infection, CCR5 antagonists might be contra-indicated in HCV/HIV co-infected subjects. Therefore, we tested the hypothesis that the level of T cell surface CCR5 expressi
Rates of initial viral suppression and durability of response of Single PI vs. Efavirenz or Boosted PI combination therapy in an unselected antiretroviral (ARV) naive urban indigent population.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12239); Visnegarwala F, Wright JA, Agarrwal M, Mestry K, Arduino RC, Lahart CJ, White AC;;;; Jr, T.P. Giordano. Baylor College of Medicine, Houston, Texas, United States; There are limited data comparing the effectiveness and durability of single PI(SPI), Efavirenz (E) & boosted PI (BPI) based first HAART among indigent patients (pts) in a non-trial setting. Methods: We conducted a retrospective analysis, using an observational database of all newly seen pts at Thomas St
Challenges in supervision of VCT counselors.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12243); Waweru HM, Bukusi D, Namwebya JH, Mulindi S, Musau F;;;; Kenyatta National Hospital, Nairobi, Kenya; Different forms of counseling are used at a national referral hospital by counselors as they strive to provide support for patients suffering from. HIV/AIDS. Counselors have to deal with situations ranging from assessing clients risks, preparing clients for testing, test result counseling, identifying sources o
Histopathologic study of papullar pruritic erruption (PPE) of HIV.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12247); Dhurat RS, Chowkekar SS, Jerajani HR, Dethe G, Shinde S, Palwade P;;;; LTMMC and LTMG Hospital, Sion, Mumbai, India; Introduction: PPE of HIV is a diagnosis that refers to nondesript papular erruption. The diagnosis is made usually by excluding other pruritic conditions. Some experts consider PPE to be variant of eosinpophilic folliculitis. Method: HIV positive patients with pruritic symmetric papules of atleast one month duration an
Tuberculosis in HIV + patients: DOT in collaboration with the offices of pharmacy. Experience in Valencia (Spain).: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12251); Jimeno A, Mellado E, Ortega E, Garcia Deltoro M, Ballester JE, Abril V, Valero I, Garcia Rodriguez M, Pavon A, Herrera A;;;; Unidad Enfermedades Infecciosas. Consorcio Hospital General Universitario, Valencia, Spain; The adherence to the treatment is a universal problem. The directly observed treatment (DOT) for the tuberculosis is a strategy that assures patients completes the treatment in dose and duration. We present the experience of tuberculosis DOT in collaboration with the offices of pharmacological dispensation.
The adherence to ARV therapy among drug users with AIDS and Tuberculosis in Sao Paulo, Brazil.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12255); Lima HL;;;; Faculdade de Saude Publica USP, Sao Paulo, Brazil; Brazil is a country with 277,154 patients with AIDS, and 120,000 in ARV therapy - 100% of those who fill the clinical criteria to aids case have free treatment to AIDS and Tuberculosis. In Sao Paulo, a lot of drug users patients are not taken care by the doctors, because they have prejudices and tell then or A
Impact of the HCV co-infection in HIV-1 infected patients treated with HAART.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12259); Marques R, Silva S, Pineiro C, Tavares M, Xerinda S, Ferreira A, Serrao R, Diaz-Brito V, Maia H, Santos M, Soares J, Mota Miranda A;;;; Infectious Diseases Department Hospital S. Joao & School of Medicine, Porto, Portugal; Viral hepatitis presumably potentiates the hepatotoxicity of the antiretroviral drugs. We aim to evaluate the impact of HCV co-infection on the frequency of liver damage and on the immunological and virological response to HAART. Methods: retrospective study of all HIV-1 infected patients (pts) who had an H
Surveillance of HTLV infection in Spain.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12263); Toro C, Bassani S, Benito R, Aguilera A, Caballero E, Rodes B, Rodriguez C, Tuset C, Calderon E, Garcia J, Ortiz de Lejarazu R, Eiros J, Alvarez P, Dronda F, Rodiguez-Iglesias M, Guelar A, Soriano V;;;; Hospital Carlos III, Madrid, Spain; The HTLV Spanish Study Group was constituted in 1991 to record the main characteristics of subjects with HTLV-I/II infection and to perform national surveys on HTLV in different populations. It includes participants from 18 centers distributed across the Spanish geography. Herein, we report data up to Decem
VCT challenges; case study.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12267); Kathambana F, Bukusi D, Mulindi S, Musau F;;;; Kenyatta National Hospital, Nairobi, Kenya; INTRODUCTION: VCT is a client-centered intervention that focuses on a client s unique issues and circumstances related to HIV risk. It is designed to be brief, with both Pre and Post -test sessions lasting 15 to 20 minutes. VCT poses many challenges to the counselors. There are many difficult situations that present th
Addressing issues on HIV/AIDS adherence: Implications for health professionals.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12271); Andujar-Bello I, Toro-Alfonso J;;;; University of Puerto Rico, San Juan, Puerto Rico; Appropriate adherence to HIV/AIDS treatment results in improving quality of life, reduction of symptoms and related opportunistic diseases. A poor adherence entails a diminution of benefits and the development of strains resistant to treatment. In HIV/AIDS treatment it is necessary to comply with 95% of the rec
Therapy Antiretroviral (TARV) used in Brazilian children - 1986 until 2002.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12275); Melo AC, Caiaffa WT, Couttolenc BF;;;; Centro Universitario Newton Paiva, Belo Horizonte, Brazil; The natural history of AIDS shows different progression patterns. ARV therapy is used to delay its progression and/or to recover the child s immunity. The objective of this study is to describe the profile of ARV use among children in reference services. Method: A probabilistic and systematic sample was tak
Factors which influence compliance to antiretroviral treatment of patients HIV infected.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12279); Cambrea SC, Rugina S;;;; Infectious Diseases Clinical Hospital, Constanta, Romania; Compliance to antiretroviral medication is a problem for HIV/AIDS patients. The compliance is the measures of personal behavior which correspond to medical advise and noncompliance rise when treatment followed by patient is different from treatment prescribed by physician. Monitoring compliance and non-comp
Challenges of testing children for HIV in community and University Teaching Hospital (UTH) and Lusaka Zambia.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12283); Chime J, Chitembo L, Bhat N, Manda KD;;;; Family Health International, Lusaka, Zambia; Family Support Unit (FSU) at University teaching Hospital Lusaka Zambia did a formative assessment to facilitate planning for provision of psychosocial support for Children living with HIV/AIDS (CLWHA). Challenges for HIV testing for children were among issues that the assessment addressed. Method: The asse
Building a cadre of AIDS barefoot doctors.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12287); Wells VE, Ngome CK, Mwiria K;;;; SOTENI Kenya, Nairobi, Kenya; The magnitude of the HIV/AIDS pandemic requires a veritable army of workers to fully prevent and mitigate its effects on the individual, family, institution, community, and world. To date, specific services have been provided by a range of professionals and paraprofessionals: peer educators, community based dis
Long-term ARV toxicity monitoring : The need for a new model.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12291); Fischer HF;;;; Act Up-Parisaris, Paris cedex 11, France; Long-term ARV toxicity is recognized as a major threat to long-term life prognosis and immediate quality of life of ARV patients. Health authorities and healthcare providers largely rely on the traditional pharmaco-vigilance system to obtain the required epidemiological data and management insights required to
How reliable is the use of fourth-generation assays for combined detection of HIV antigen (Ag) and antibody (Ab) for clinical diagnostic purpose.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12295); Ueda M, Oliveira CA, Yamashiro R, Mota EA, Campos AR, Fernandes A, Barreira D, Felinto M;;;; Adolfo Lutz Institute-Sao Paulo State Secretariat of Health, Sao Paulo, Brazil; HIV/AIDS diagnosis has been performed by means of Abs detection. In 1998, Brazilian Ministry of Health established an algorithm for HIV/AIDS serological testing, and modified in Jan/2003. Recently, HIV Ag / Ab combined EIAs have been available, and they have been useful for blood donors screening as they permit
An analysis of nelfinavir adherence, resistance, and HIV viral load.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12299); Wutoh AK, Daftary M, Xue Z, Nwankwo EA;;;; Howard University, School of Pharmacy, Washington, United States; A study was conducted to assess the role of antiretroviral adherence and HIV viral load on subsequent development of HIV viral resistance. Eleven HIV-infected patients were enrolled into this study, all patients were prescribed nelfinavir in combination with at least two other antiretrovirals (ARV). Four patients were
Toxoplasmic encephalitis in 110 adult Thai AIDS patients: a retrospective review.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12303); Mootsikapun P, Chetchotisakd P, Anunnatsiri S;;;; Department of Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand; To describe clinical manifestation, radiologic findings of toxoplasmic encephalitis (TE) in Thai AIDS patients in one tertiery care medical center in Northeastern part of ThailandStudy design: A retrospective study was performed at Srinagarind hospital, KKU during 1992-2002. Method: Medical records of adult
The impact of age on medication adherence in HIV infection: A longitudinal investigation.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12307); Barclay TR, Castellon SA, Hardy D, Lam MN, Keuning A, Robinet M, Myers H, Durvasula RS, Hinkin CH;;;; VA Greater Los Angeles Health Care System, Los Angeles, California, United States; Successful management of HIV infection depends not only on the efficacy of pharmacological agents, but also on the extent to which patients comply with treatment. Despite the dramatic decline in morbidity and mortality associated with the advent of antiretroviral therapy, medication adherence remains a crit
Anti-retroviral adherence in a resource poor setting.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12311); Akam AW;;;; Provincial Hospital Limbe, Limbe, Cameroon; Adherence may vary from one setting to another, and in the same setting from one patient to another. Poor adherence is the major cause of therapeutic failure. In resource poor setting, anti-retroviral adherence has frequently been described as poor due to several reasons. Patients and/or patients relatives
Adherence to antiretroviral (ARV) therapy among advanced-stage, indigent patients in the funded ESTHER programme in Kigali, Rwanda.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12315); Omes C, Schuman M, Kamesigwa J, Demeester R, Mukakalisa J, Parisel A, Kayibanda E, Arendt C;;;; Centre Hospitalo-universitaire de Kigali, Kigali, Rwanda; Providing ARV to poor patients with advanced disease raises concerns about adherence to therapy for reasons related to poverty, drug intolerance and drug interactions. Our aim was to study the adherence to therapy among patients started on ARVs within the funded ESTHER programme at the Centre Hospitalier de
Prevention of Mother-to-Child-Transmission of HIV by short dual therapy in the Western Cape Province of South Africa.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12319); Draper BH;;;; University of Cape Town, Cape Town, South Africa; In 1999 single dose therapy for prevention of mother-to-child transmission was introduced in the province. Short course Zidovudine was initiated at a pilot site in Khayelitsha, a high prevalence district. The program was rolled out to other sites using Nevirapine as a take-home
Integration of private sector in community-based tuberculosis enhances implementation of cb-dots strategy.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12323); Mugizi C, Turyashemerwa P;;;; IPH/CDCFellowship Program, Kampala, Uganda; Tuberculosis control efforts were introduced in Uganda in 1965. However this was interfered with by the political instability seen in the country in the period of 1970 s and 1980 s. The National Tuberculosis/Leprosy Control Program was conceived in 1988 and launched in 1990 to improve the TB control efforts.10
Establishing a PMTCT program in primary health care services: needs assessment.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12327); Sanou KA, Ouedraogo SM, Traore TT, Ky-Zerbo O, Fao P, Meda N;;;; Centre MURAZ, Bobo-Dioulasso, Burkina Faso; A needs assessment for Kesho-Bora project implementation (use of HAART to reduce Mother to Child Transmission of HIV and improve maternal health) in Bobo-Dioulasso was conducted in May 2003 in 16 Maternal and Child Health Services (MCH). Methods: A structured questionnaire was administered on persons in cha
HIV impact on friendly and affective relations as a potential factor of adherence: evidence from a large representative sample of outpatients attending French hospitals (VESPA/ANRS 2003).: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12331); Peretti-Watel P, Spire B, Riandey B, Obadia Y;;;; Inserm U379, Marseille, France; Since the advent of highly active antiretroviral therapies (HAART), adherence to HAART has become a major issue in HIV/AIDS care, but few quantitative studies have considered HIV impact on friendly and affective relations as a potential factor of adherence. This study focused on two aspects of such impact:
The different ways of involvement in treatment: a another look at treatment compliance.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12335); de Montaigne AB, Parizot I, Chauvin P;;;; INSERM - U444, Paris, France; HAART efficacy depends on patients compliance with pharmacological requirements. The aim of this qualitative study is to understand the process in which daily treatment actions of HIV persons are defined and the process of compliance. Methods: 74 HIV persons receiving HAART treatment were in depth interview
Predicators of longitudinal nonadherence among clients enrolled in the treatment adherence demonstration project.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12339); Waters M, French PT, Weiss L, Finkelstein R, Agins BD;;;; New York State Department of Health, AIDS Institute, Albany, United States; Since 1999, the NYSDOH AIDS Institute has provided funding to help individuals adhere to their HIV antiretroviral treatment regimens. Treatment adherence programs were required to form a network of clinical and community-based support services in order to meet the multiple needs of HIV-infected individuals.
Advantages of directly observed therapy (DOT) in the administration of HAART to HIV/AIDS children/adolescence.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12343); Omo-Igbinomwanhia NE, John D, Downes A, Thomas C, Stapleton S, John J;;;; Cyril Ross SVP Nursery, Tunapuna, Trinidad and Tobago; Comparing the outcome of treatment amongst 50 children on HAART in an HIV/AIDS treatment center for children in Trinidad and Tobago . Using the changes in CD4+ lymphocyte count and HIV-1 RNA viral load over a period of 2years.
Deep relaxation anti-stress therapy in people living with HIV and AIDS as an effective control technique.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12347); Medina JA, Ponce J, Parra HJ;;;; Alianza Lambda de Venezuela, Caracas, Venezuela; HIV patogenic effect handles an immunologic system down-low, ending in AIDS status. Considering stress the aggressive factor against, getting worse PWA, and disturbing TCD4 and cells NK status. We enhanced a pilot study, assuming clinic and experimental strategy with a double-test evaluation, over the deepe
Role of the determination of plasma levels of indinavir to predict the virologic failure.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12351); Martin V, Ortega L, Cuevas MJ, Mostaza JL, Perez-Simon R, Villares C, Gutierrez B, Alcoba M;;;; University of Leon, Leon, Spain; To asses the contribution of the determination of concentrations of indinavir in plasma to the assessment of self-reported adherence and keeping of appointments to withdraw drugs from the hospital pharmacy in the prediction of the virologic failure. Methods: Prospective observational study in patients with
Morisky questions as a tool to evaluate adherence to antiretroviral therapy in public primary care clinics in Rio de Janeiro, Brazil.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12355); Hofer CB, Schechter M, Harrison LH;;;; HUCFF-Universidade Federal do Rio de Janeiro and GSPH-University of Pittsburgh, Rio de Janeiro, Brazil; Adherence to antiretroviral therapy (ART) is a determinant of survival in HIV infection. Self-reported adherence (RA) is a commonly-used method for measuring adherence to ART. In 1986, Morisky et al. validated a 4 objective questions for measuring adherence. Each affirmative response indicates a lack of adh
Adherence to ART in clinical trial settings in Zimbabwe and Uganda: lessons learned.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12359); Day J, Godoka N, Nyamapfeni P, Chigwanda M, Muzunze B, Basikoro P, Makumbirofa S, Kaye G, Nankya J, Mpairwe B;;;; Family Health International, Research Triangle Park, NC, United States; Increased access to ART in resource-poor countries may lead more clinical trials to offer ART as part of the standard of care. Clinical trials, with greater access to resources, may provide an ideal environment for adherence. However, external factors can still impact adherence. Few studies have examined ART ad
Trends in genotypic resistance in clinical samples submitted for routine HIV resistance analysis.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12363); Mackie NE, Sabin C, Dustan S, Clarke JR, Weber JN;;;; Faculty of Medicine, St Mary's Hospital, Jefferiss Wing Laboratories, Wright-Fleming Institute, Imperial College, London, United Kingdom; Resistance to antiretroviral drugs is a major factor contributing to failure of HIV therapy. Patterns of resistance may change over time according to patients tested, treatment strategies and introduction of new agents. Methods: In-house sequencing of HIV pol has been performed on plasma samples with >50 HI
Agroforestry and HIV/AIDS: Indigenous knowledge, validation and conservation of medicinal plants for HIV care.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12367); Homsy J, Boffa JM, Swallow B, Bitahwa N, Weisheit A, Simons T;;;; THETA, Kampala, Uganda; Indigenous medicinal plants, mostly wild harvested, are widely used by traditional healers and people living with HIV/AIDS (PLHAs) in sub-Saharan Africa for the management of opportunistic infections and immune stimulation, yet little effort has been devoted to their documentation, validation, utilisation,
Lack of efficacy of zidovudine, lamivudine and abacavir as initial therapy for antiretroviral-naive patients with AIDS.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12371); Rivas P, Gorgolas M, Goyenechea A, Garcia R, Becares J, Fernandez-Guerrero ML;;;; Division of Infectious Diseases/Fundacion Jimenez Diaz/Universidad Autonoma de Madrid, Madrid, Spain; Introduction: Efficacy of zidovudine, lamivudine and abacavir combination ( Trizivir ) on naive full-blown AIDS patients has not been defined. Methods:43 patients with less than 200 CD4 and/or any AIDS defining condition were enrolled in a prospective non-controlled t
Use of outreach services in scaling up the uptake of Prevention of Mother to Child Transmission of HIV (PMTCT) services. Kabarole District Health Services, Uganda.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12375); Amanyire G;;;; Makerere University Institute of Public Health, Kampala, Uganda; Integration of services that prevent mothers from transmitting HIV to their babies into the traditional outreach programmes like immunisation and family planning, has improved their uptake in a rural set up in Uganda . Vertical transmission is the second major mode of transmission of HIV in Uganda, accounting f
Antiretroviral use, side effects and adherence among HIV-infected persons in medical care in the U.S.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12379); Smith JJ, Mayer KH, Sandman D, Frost KR;;;; American Foundation for AIDS Research, New York, NY, United States; Medical management of HIV-infected persons is complex, so a multi-center survey was designed to evaluate the HIV knowledge, treatment satisfaction, and behaviors of persons receiving medical care in the U. S. Methods: A self-administered survey was conducted at 8 diverse clinics in 7 cities (July 02-Februar
Parasitosis in HIV - infected people in the national hospital service of internal medecine and infectious diseases. Bamako - Mali.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12383); Minta D, Dembele M, Dolo A, Sidibe AT, Diakite A, Ouattara A, Sidibe AF, Thera MA, Pichard E, Traore HA, Doumbo O;;;; Hospital of PointG, Bamako, Mali; Our aim was to study digestive parasitosis in hospitalized patients in the services of Medecine intropical areas. We conducted from january to december 2002 an exhaustive study in services of internal medecine and infectious diseases of National hospital of Point G of Bamako. 205 patients were concern by the study amon
Injecting Drug Users and the care & treatment.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12387); Waikhom R;;;; Care Foundation, Imphal, India; Hard to achieve quality care and treatment amongst current injecting drug users. Failing to adhere causes constant drop outs from the treatment. Treatment becomes secondary to drug using thus leading to treatment failure. High chances of transmitting the mutant virus that maybe drug resistant. CARE
Demyelinating illness in a patient with HIV.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12391); Ball SC, Edgar M, Jacobs J;;;; Center for Special Studies, New York Presbyterian Hospital, Weill College of Medicine, Cornell University, New York, United States; Demyelinating illness has been described in patients with HIV. MS-like lesions. Were described by Berger in a group of HIV+ patients in 1989. Langford et al. described a series of AIDS patients who had failed HAART and who had severe demyelinating leukoencephalopathy on autopsy in the absence of JC virus, EBV,
Compliance to QD dosing versus BID/TID dosing of antiretroviral agents in rural North Carolina HIV/AIDS population.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12395); Torres R, Reebye U;;;; SRAHEC, Newton Grove, United States; The use of HAART regimens has reduced of mortality, opportunistic infections and hospital admissions in patients infected by the human immunodeficiency virus. However, due to the cumbersome dosing schedule, many patients are not compliant with their therapy. HIV+ patients in rural North Carolina, due to the
Higher incidence of premature craniosynostosis in HIV-1 exposed children.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12399); Dunsch D, Koenigs C, Linde R, Elanjikal Z, Scheuplein M, Vlaho S, Boda V, Faul-Burbes C, Haberl A, Schmidt H, Kieslich M, Klingebiel T, Kreuz W;;;; JWGoethe University Childrens Hospital, Paediatric Immunodeficiencies, Frankfurt, Germany; The incidence for premature craniosynostosis is approximately 1: 2000 live births. A craniosynostosis may affect coronal, sagittal, metopic and lambdoid sutures in isolation or in combination and results in redirected growth and abnormal headshape. Till now the biomolecular mechanisms mediating cranial suture biology r
Kaposi's Sarcoma - a review of 162 patients (1985-2003).: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12403); Grilo A, Asensio N, Rodrigues P, Cardoso O, Martins T, Correia F, Machado J, Maltez F;;;; Curry Cabral Hospital, Infectious Diseases Department, Lisbon, Portugal; The authors reviewed all clinical cases of Kaposi s Sarcoma associated with HIV infection admitted at the male ward of an Infectious Diseases Department from 1985 to 2003. Objectives: characterization of incidence, associated behaviors, clinical features, opportunistic infections, therapy and outcome. Metho
Abacavir and tenofovir combination therapy in clinical practice.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12407); Ward DJ;;;; Dupont Circle Physicians Group, Washington, DC, United States; As demonstrated in ESS30009 the triple-nucleoside regimen of tenofovir (TFV), abacavir (ABC) and 3TC has an unacceptably high rate of virologic failure.
An extraordinary case of AIDS mania: an old problem in a new era.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12412); Nims C, Ferrando SJ;;;; Weill Medical College of Cornell University, New York City, United States; AIDS mania is a syndrome seen in late-stage AIDS in conjunction with HIV-associated dementia (HAD). It is distinct from primary bipolar illness and has a poor prognosis. Effective ART has reduced the incidence of HAD. As a result, the diagnosis of concomitant AIDS mania may be overlooked. This pape
Massage therapy intervention to enhance well-being in HIV+ Dominican children: preliminary results.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12416); Shor-Posner G, Hernandez-Reif M, Baez J, Solange S, Miguez MJ, Perez-Then E, Fletcher MA, Diaz R, Zhang G;;;; University of Miami School of Medicine, Miami, United States; Antiretroviral therapies are not widely available for HIV+ children in the Dominican Republic . The present study evaluated the efficacy of massage therapy, which has been demonstrated to increase immune capacity in HIV+ adults, to preserve immune function in HIV+ Dominican children. Methods: Following IRB
Fertility and the perinatally acquired HIV-infected female: a new public health dilemma.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12420); Thomas AM;;;; St. Joseph's Regional Medical Center, Paterson, New Jersey, United States; Since the development of the Pediatric AIDS Clinical Trials Group (PACTG) Protocols, the risk of mother-to-child transmission has dramatically decreased. Prior to the protocols, the prognosis of children born to mothers with AIDS was poor. However, the advances of antiretroviral therapy have increased the life
Atazanavir boosted with ritonavir in protease inhibitor-naive patients.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12424); Uy JP, Wendrow A;;;; University of Illinois at Chicago, Chicago, United States; Atazanavir (ATV), a protease inhibitor (PI), was approved by the US FDA for the treatment of HIV in June, 2003. Data on the ATV boosted with ritonavir (ATV/r) is limited to its use in PI-experienced patients.
Adherence to antiretroviral therapy (ART) among HIV perinataly-infected children in Sao Paulo, Brazil.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12428); Yu CL, Della Negra M, Queiroz W, Pacola DP;;;; Inst. Infectol. Emilio Ribas, Sao Paulo, Brazil; To analyse the adherence rates to (ART) among HIV perinataly infected children in a country where the access to antiretroviral drugs is granted for free by the government, according to the kind of caregiver. METHODS: The caregivers from 307 children receiving ART for more than 6 months answered to a standar
Oxymetholone as therapy to maintain body composition in HIV positive men.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12432); Urbina A, Miller M, Hance I;;;; St. Vincent Catholic Medical Center-Manhattan, New York, United States; While protease inhibitors (PIs) are improving chances of survival in HIV, studies show that people who experience success with PIs regain fat mass, rather than LBM when they regain weight. Androgenic/ anabolic steroids (AAS) have been shown to improve LBM in HIV and to reduce the fa
Faith-based collaboration- St Mary's Hospital Nairobi Kenya and Catholic Medical Mission Board (CMMB): A proposed model of locally-appropriate access to HIV care for HIV-positive women and their families within East Africa.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12436); Fryda B, Maina M, Konya W;;;; St. Mary's Hospital/CMMB, Nairobi, Kenya; A locally-appropriate working model of HIV care designed for affordability, patient compliance, and dissemination throughout East African medical facilities is outlined. The model is based upon experience of what is workable and maintainable within the local African environment, with emphasis upon restorat
Nutritional and metabolic disorders in HIV-infected children of poor settings: the Yopougon Child Program (ANRS 1278, Abidjan, Cote d'Ivoire.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12440); Mercier-Deheuvels S, Laguide R, Kouakoussui A, Msellati P;;;; IRD , Montpellier, France; Context: Beyond the age of 3, very few things are documented on the evolution of AIDS in infected children of poor-settings. Use of HAART is still poorly documented in terms of impact, and prevalence of resistances in children. Malnutrition, already alarming for these children, is one of the major complications of AIDS
Clinical epidemiology of Histoplasmosis in HIV infected patients in Cali, Colombia.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12444); Galindo J, Galindo X, Miguez-Burbano MJ, Onate JM, Parra LA, Shor-Posner G, Restrepo A;;;; Corporacion de Lucha contra el SIDA, Cali, Colombia; Histoplasmosis is an increasing problem in HIV+ patients in certain areas of Latin America and its diagnosis poses a significant challenge. Methods: The present study described the clinical parameters of 16 confirmed cases of histoplasmosis in HIV infected individuals in Cali,
Assessment of the correlation between CD4 surface marker on circulating T-Lymphocytes and HIV plasmatic viremia of HIV-positive subjects by means of Flow Cytometry tools and Viral load.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12448); Oliveira CA, Rossini MA, Ribeiro TZ, Campos NC, Santos IM, Ueda M;;;; Adolfo Lutz Institute-Sao Paulo State Secretariat of Health, Sao Paulo, Brazil; Flow cytometry (FC) parameters can be used to assess cell surface markers expression. Plasmatic HIV viral load (VL) has been employed to monitor HIV patients under antiretroviral treatment. We conducted a cross-sectional study to evaluate the correlation between CD4 expression profile on T-lymphocytes (Tly)
Subjective beliefs about health status and health care providers significantly predict adherence to anti-retroviral medications.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12452); Temoshok LR, Wald RL;;;; Institute of Human Virology, Baltimore, MD, United States; Our lab and others have found that a variety of psychosocial factors predict adherence to HAART, including cognitive and memory problems, depression, life stressors, and socioeconomic deprivation. However, the role of the patient-provider relationship has often been under-emphasized in prior research. Metho
Public health implications of viral Hepatitis and HIV co-infection in South Africa.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12456); Conway SB, Dayal DB, Gray G, McIntyre J;;;; Perinatal HIV Research Unit, Johannesburg, South Africa; Impaired liver function tests and co-infection with hepatitis viruses are commonly associated with HIV disease in western countries and have implications for selecting antiretroviral therapy treatment protocols and adopting screening procedures and prevention strategies within public health programmes. Ther
An education and support workshop for people living with HIV-related lipodystrophy.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12460); Finlon CJ;;;; Center for Special Studies, NY Presbyterian Hospital, New York, NY, United States; HIV-Associated Lipodystrophy (HAL) is a complication of HIV treatment and/or infection that can lead to depression, lowered self-esteem, reduced socialization and compromised treatment adherence in those affected. Physical changes resulting from HAL may be experienced as markers of HIV infection causing individu
HIV Aggressivity Test (HIVAT: combined highly affordable CD4_8_45_38 assay) for defining the spread and severity of HIV disease in African & Asian populations.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12464); Janossy G, Martins S, Bolsover H, Kinloch de Loes S;;;; Royal Free Hospital, London, United Kingdom; In the West, HIV monitoring employs equipments in hemato-, immuno- & virology with costs of >$110/assay that is unacceptable for Africa and Asia. We asked whether HIV monitoring and epidemiology can be performed on a 2-colour flow cytometer at a cost of $3-6, and whether transport fluid for stabilising
Establishing the evidence base for palliative care to the medically-underserved with HIV/AIDS.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12468); Raveis VH, Karus D, Marconi K, Higginson IJ, Hanna B, Alexander C, Selwyn P, Ratcliff M;;;; Mailman School of Public Health, Columbia University, New York, NY, United States; The global burden of HIV/AIDS continues to grow. For those unable to tolerate treatment or for whom aggressive therapy is not available or no longer effective, palliative care is essential. Ensuring appropriate care for individuals dying with HIV/AIDS is a significant issue. Effective program planning and servi
A comparison of pre and post menopausal HIV infected African American women at an inner city minority teaching hospital.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12472); Maxwell C, Reddy R, White-Coleman D, Taylor G, Johnson K;;;; Howard University Hospital, Washington DC, United States; Middle aged and older women represent over 25% of all women with AIDS and 4% of all reported AIDS cases in United States . Studies have shown that older HIV infected patients have poorer outcomes compared to younger patients. This retrospective study aims to evaluate the difference if any, in risk factors,
Use of two spanish translated instruments (SMAQ and AACTG questionnaires) to evaluate prevalence of non-adherence to antiretroviral treatment in HIV infected subjects in Mexico City.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12476); Perez-Patrigeon S, Franco-SanSebastian D, Soto-Ramirez LE, Villasis-Keever A, Sierra-Madero J;;;; INCMNSZ, Mexico City, Mexico; Introduction: Inadequate adherence is the most important factor predicting failure to HAART in HIV-infected subjects. With the recently implemented government-funded antiretroviral program in Mexico , use of HAART is now widespread in this country, however the prevalence of non-adherence and the optimal instruments hav
Family support unit improves care and support to HIV infected children and their caregivers in Lusaka Zambia.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12484); Bhat GJ, Bwalya VC, Chitembo L, Chime J, Manda KD;;;; University Teaching Hospital, Lusaka, Zambia; The number of children infected with HIV continues to grow in Zambia . HIV sero -prevalence among hospitalized children at the University Teaching Hospital (UTH) Lusaka has increased from 20% in 1992 to 39% in 2000. We describe our experience in providing care and support to HIV infected children and their care
CD4 cell count and viral load for staging initiation of anti-retroviral therapy in HIV-subtype C infection.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12488); Peter T, Novitsky V, Sebetso G, Zavahir S, Mattunda S, Nkoane T, Gaolekwe S, Thior I, Kim S, Widenfelt E, Marlink R, Essex M;;;; Botswana-Harvard AIDS Institute Partnership, Gaborone, Botswana; In estimating of the numbers of people who require antiretroviral therapy for HIV in Africa, accurate estimates are needed of the number infected and of the proportion of those infected who currently have AIDS. Estimates AIDS patients might be collated from medical records, but few estimates exist of the nu
Measuring medication adherence AIDS patients in Thailand: A pilot study.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12492); Maneesriwongul W, Willaims A;;;; Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand; Failure to take antiretroviral medications as prescribed results in sub therapeutic drug levels and frequently leads to viral resistance. In response to the recognition of medication adherence in achieving maximum antiretroviral benefit, a pilot study was conducted to examine the feasibility of conducting m
Use of cotrrimoxazole as an antimalarial prophylactic drug among HIV adult patients : the pros and cons.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12496); Ndir A, Soumare M, Landmann R;;;; ISAARV, Dakar, Senegal; Malaria and HIV are the two commonest infections in subsaharan Africa which have serious consequences in the evolution of affected persons. This paper was performed to describe the benefits and limits of the use of cotrimoxazole as an antimalarial prophylactic drug among HIV adult patients. Methods: This pa
Effectiveness of an interdisciplinary team on end-of-life care.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12500); Alexander CS, Lawler J, Perrone M, Tommasello A;;;; University of Maryland/Institute of Human virology, Baltimore, Maryland, United States; To evaluate the use of a hospice interdisciplinary team supplemented with an addictions counselor and an outreach worker for describing the impact of end of life(eol) on persons with advanced AIDS living in an inner city coping with access barriers such as homelessness, active intravenous drug use, frequent
Guidelines for surveillance of HIV drug resistance among newly diagnosed, drug naive persons. A pilot test in Mexico.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12504); Bertagnolio S, Soto Ramirez LE, Sobel H, De Felici AP, Lazzari S, Sutherland D;;;; WHO, Geneva, Switzerland; WHO recommends that countries planning to implement ART programs also consider implementation of HIV Drug Resistance (DR) surveillance among drug naive, newly diagnosed subjects. This will allow to detect transmission of HIVDR, to evaluate temporal trends and thus influence policy makers decisions on treatment
Hepatitis B virus in antenatal clinics in Vellore, India.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12508); Buck J, Lionel J, Gopalakrishnan G, Cu-Uvin S, Flanigan T, Mayer K, Jasper P;;;; Christian Medical College and Hospital , Vellore, India; Most antenatal clinics in South India now screen for HIV. Hepatitis B Virus (HBV) is transmitted through the same routes as HIV and is much more infectious, yet it is often overlooked. Methods: Retrospective review of CMC Hospital antenatal clinic records was done to determine HbSAg seroprevalence rates fro
The effect of peer counseling on adherence in women in a managed care setting.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12512); Jones J, Ranta V, Corbett D, Stein B, Guide N;;;; MetroPlus Health Plan, New York, United States; Health plan based peer counseling can improve treatment adherence. MetroPlus Health plan is a medicaid managed care plan and part of the NYC Health and Hospitals Corp.. This study looked at the use of a plan based peer counselor to improve adherence to MD visits and HAART in HIV+ Women. Methods: An HIV+ fem
Efficacy of Tenofovir and Zidovudine/Lamivudine at 48 weeks for the treatment of HIV.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12516); Alvarez-Arnao DF, Witek J, George K;;;; Drexel University College of Medicine, Philadelphia, United States; High rate of virologic failure have been reported with several triple NRTI antiretroviral regimens (ART). We studied the safety and efficacy of a combination of tenofovir DF (TDF) and zidovudine/lamivudine (CombivirR) (COM). This combination is attractive due to the complex resistance interaction among thes
The access and use of antiretroviral (ARV) medications among persons living with HIV/AIDS (PLWHAs) in Jamaica.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12520); Campbell A, Ward E, Schwartz I;;;; Ministry of Health, Kingston, Jamaica; To assess the ease of access and use of ARVs among Persons Living with HIV/AIDS (PLWHAs) in Jamaica and to describe the predisposing, enabling, and illness level characteristics of (PLWHAs) that access and use antiretroviral (ARV) medications in Jamaica. Methods: A descriptive study using convenience-samplin
Enrolling HIV-infected mothers, partners and children into care in four provinces in Thailand.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12524); Kanshana S, Rakseree S, Amornwichet P, Teeraratkul A, Ngamsiriudom B, Limtrakul A, Boonamnauykij B, Thewanda D, Ru Lo Y, Bamber S, Tappero JW, Culnane M;;;; Department of Health, Ministry of Public Health, Nonthaburi, Thailand; Through a new public health initiative, HIV-infected women identified through the prevention of mother-child HIV transmission (PMTCT) program and their infected family members will have access to CD4 cell counts, highly active antiretroviral therapy (HAART), and other care services that were previously unav
A nurse-based HIV disease state management model on the U.S.-Mexico Border.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12528); Jones A, Wiebe JS;;;; Centro de Salud Familiar La Fe CARE Center, El Paso, TX, United States; HIV/AIDS care in resource-poor communities on the U. S.- Mexico border has long faced serious challenges, including scarce funding, a dearth of qualified and trained bilingual infectious disease physicians, and decentralized service provision, with patients seeking different health services from multiple provid
Reliable CD4 T-cell enumeration in Brazil. The impact of single platform absolute counting technology with a linage specific marker and an external quality assessment program.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12532); Mandy F, Bergeron M, Houle G, Azevedo L, Grangerrio A;;;; Health Canada, Ottawa, Canada; Measurement of CD4 T-cells is important to evaluate and treat HIV disease. This report is about the effectiveness of T-cell gating with single platform absolute cell counting technology using mostly FACSCount instruments. In 1997, QASI, an international program for external quality assessment (EQA) was initiated. It op
What do our patients know?: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12536); Rosa VK, Gomes MG, Schuh SS;;;; SEM Alvorada, Alvorada, Brazil; Background : This work is the partial result of an evaluation of the Adhesion in a community located in the South region of Brazil . Dawn is a city located in the metropolitan area of Porto Alegre in the State of Rio Grande do Sul, Brazil. Our intention is to verify the basic information about Aids of the patients and
Human rights protection as a component of comprehensive HIV care in northern Thailand.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12540); Wandee P, Supawitkul S, Kaewkampa P, Summanapan S, Chanmangkang S, Yuktanon P, Chaiyanon Y, Sinsomboonthong S, Srisongsom S, Virapat P, Tappero JW, Levine WC;;;; Chiang Rai Provincial Health Office, Chiang Rai, Thailand; Background : Since 1997, protection of human rights for persons living with HIV/AIDS (PLHA) has been supported by the Thai Ministry of Public Health as a vital component of comprehensive HIV care. However, few data exist on the extent to which this policy has been implemented locally. Methods : We collected information
Use of pneumonia severity index and outcomes of community acquired pneumonia in HIV positive and HIV negative patients at an inner city hospital.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12544); Nutankalva L, Mody VR, Reddy R;;;; Howard Universtiy Hospital, Washington D.C, United States; Background : Community acquired Pneumonia accounts for an increasing proportion of pulmonary infections in patients with HIV infection. Many studies has shown that the outcomes for CAP were worse for those with HIV compared with non HIV patients and PSI (Pneumonia Severity Index) is much higher in HIV positive patients
Symptom management of diarrhea in HIV/AIDS.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12548); Hamilton MJ, Sefcik E, Tsai Y, Nicholas P, Corless I, Dole P, Kemppainen J, Coleman C, Wantland D, Eller L, Holzemer W, Reynolds N, Kirksey K, Nokes K;;;; Texas A&M University-Corpus Christi, Corpus Christi, United States; People living with HIV/AIDS are challenged to manage symptoms related to the disease, treatments and co-morbidities. This study extends earlier work that described the frequency and correlates of self-reported HIV symptoms and self-care behaviors used to manage diarrhea in an international sample. Methods:
Adherence to antiretroviral treatment among HIV-positive children in Guayaquil, Ecuador.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12552); Mino GP, Beck A, Lewis J, Salazar JC;;;; University of Connecticut, Farmington, United States; The aim of this study was to assess adherence to HAART (highly active antiretroviral therapy) in 53 HIV-positive children being treated at the Children s Hospital Dr Francisco de Icaza Bustamante in Guayaquil, Ecuador . We also wanted to determine whether the following parameters have an effect on adherence
Incidence of vertical transmission in HIV-positive inner city pregnant women treated with HAART during second and third trimester.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12556); Greiger-Zanlungo P, Smith C, Blick G, Garton T, Patel B, Anderson C, Agnant G, Deshmukh J;;;; Mount Vernon Hospital, Mount Vernon, United States; Vertical transmission of HIV can be drastically reduced when HIV-positive pregnant women are appropriately treated with HAART during the second and third trimesters. The goal of this prospective study was to evaluate the efficacy of HAART in reducing maternal-fetal transmission of HIV-1 in an inner city pop
Humoral immune responses to Tuberculosis Glycolipid Antigen (TBGL) in TB patients and in HIV positive individuals in Heilongjiang province, China.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12560); Ling H, Hattori T, Gu HX, Ashino Y, Liu YC;;;; Department of Microbiology/Harbin Medical University, Harbin, China; Monitoring the humoral immune responses against TB in TB patients and in HIV infected individuals has potential implications for preventing the emergence of multidrug-resistant strains and the controlling growing HIV/AIDS epidemic with TB. Methods: 141 patients with active tuberculosis , 122 HIV negative
Learning from other country - how to adapt Northern Thailand's model of day care centre in Ho Chi Minh city, Vietnam.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12564); Ricard D, Tam NM, Giang LT, Thao TL, Khue LN, Fujita M, Oanh KT;;;; Health Service, District 8, Ho Chi Minh City, Vietnam; By the end of year 2003, there were approximately 150,000 people living with HIV/AIDS in Vietnam . However, the country had no real effective and concrete model for HIV/AIDS care and support. There was an urgent need for a care and support model which workable and effective in Vietnam. Meanwhile, Day Care Centr
Causes of morbidity in HIV infected patients during the early phase of antiretroviral treatment. PSF/Kigali-Rwanda.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12568); Kayitenkore K, Atkinson J;;;; Projet San Francisco, Kigali, Rwanda; HIV infected patients in resources limited settings have now more chances of accessing antiretroviral treatment. Unfortunately, this treatment is often started late in their disease and in patients with poor nutritional status. Clinicians are therefore challenged with multiple complications during the three to
Opportunistic infection prophylaxis for persons living with HIV/AIDS in northern Thailand.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12572); Leusaree T, Changmangkang S, Simmons N, Lertpiriyasuwat C, Khemngern P, Wongtongkam N, Srisongsom S, Levine WC, Tappero JW, Supawitkul S, Siraprapasiri T;;;; Office of Disease Prevention and Control - Region 10, Thailand Ministry of Public Health (MOPH), Chiang Mai, Thailand; Thailand s national guidelines for HIV care recommend preventive medications for common opportunistic infections (OIs), which are now covered by universal health insurance. Methods: In three northern provinces with high HIV prevalence, 31 hospitals, 389 community health centers, and 1,015 persons living wit
Implementation of preceptorship training program, Botswana.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12576); Riley A, Darkoh E, Mazonde P, Fantan T;;;; ACHAP, Gaborone, Botswana; Preceptorship Training Program provides rapid facility based cadre specific theoretical and clinical training to all relevant cadres of health workers in all ARV sites in Botswana . Identify institutions to supply your program HIV/AIDS specialist physicians and nurses on 3-6 monthly rotations. Sign
Follow up of children of HIV seropositive women from a cohort in rural South India - A clinical report.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12580); Shoba D, Parameshwari S, Jacob SM, Samuel NM, Samuel NM;;;; Department of Experimental Medicine, TN Dr MGR Medical University, Guindy, Chennai, India; From a MTCT center, in Namakkal district hospital of Tamilnadu, India , the seropositive women who were offered ARV prophylaxis to prevent vertical transmission formed a cohort (June 2000 to Nov.2003). A group of these women and their children were reviewed to ascertain the clinical status of the children.
Access for all: From medication to meditation as means for returning to harmonious life.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12584); Chuaprapaisilp A, Liamthong S;;;; Faculty of Nursing, Prince of Songkla University, Songkla, Thailand; Persons living with HIV/AIDS (PWHA) suffer severely from signs and symptoms of the disease, opportunistic infections and financial as well as social burdens. Routine health-care services cannot reduce these sufferings. In Thailand some critically ill patients adopt meditation and mindfulness to overcome the
Selection criteria of preceptors for preceptorship training program in Botswana.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12588); Riley A, Darkoh E, Mazonde P, Fantan T;;;; ACHAP, Gaborone, Botswana; Preceptorship training program trains all relevant health care workers in all ARV sites in Botswana . Preceptors are HIV / AIDS specialist physicians and nurses from partner institutions abroad who are seconded to each site for 6 months to provide cadre specific theoretical and clinical training. Preceptors pro
Concerns about third world treatment for HIV/AIDS.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12592); Bartholomew C;;;; The Medical Research Foundation, Port of Spain, Trinidad and Tobago; The Caribbean has the second highest prevalence rate of HIV/AIDS and with the discounted prices of antiretroviral drugs, and the philosophy of patients before patents, the government of Trinidad and Tobago (pop. 1.3 million) was at last able to purchase drugs f
Living with HIV/AIDS: women percetion of care and support from family members and health workers in Tanzania, December, 2003.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12596); Semguruka EM, Astril B, Ndenzako F;;;; WHO Country office for Tanzania, Dar Es Salaam, Tanzania; While care and support for people living with HIV/AIDS is taking a new toll, the use of anti retral viral drugs remain a dream to many women living with HIV/AIDS in Tanzania . The family members and relatives provide most of the support and meeting all the treatment costs. The objective of the survey was to assess the
Nutritional status changes in HIV-infected patient receiving HAART.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12600); Agostini M, Trape L, Nannini E, Lupo S;;;; Instituto CAICI, Rosario, Argentina; The maintenance of body cell mass is critical for survival in HIV infection. The purpose of this study is to assess clinical and metabolic change in patients receiving HAART. Methods: We evaluated 54 patients HIV + with HAART. Make dietary intake assessment, physical examination, anthropometry and bioimpeda
Hepatitis B virus infection in human immunodeficiency virus seropositive patients at the University Teaching Hospital, Lusaka, Zambia: Interrelationship.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12601); Sakala IG, Kasolo FC, Baboo KS;;;; University Teaching Hospital, Lusaka, Zambia; Hepatitis B virus (HBV) is frequently found in human immunodeficiency virus (HIV) infected hosts, because of their shared route of transmission. Few studies have been conducted in developing countries to establish the seroprevalence of hepatitis B infection and its interrelationship with HIV infection.
Barriers to the uptake of VCT in PMTCT in Northern Free State, South Africa.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12605); Krah CK;;;; Twifo Oil Palm Plantations Clinic, Cape Coast, Ghana; South Africa is reported to have the fastest growing rate of HIV with sero-prevalence rate of 30% in antenatal clinics in some provinces including the Free State Province. It was estimated that 50,000 infected babies were born each year in the country in the absence of programmes to prevent vertical transmi
Early clinical outcome of patients enrolled by national access to antiretroviral for pha programme in region 9.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12609); Chaiyamahapurk S;;;; Office of Disease Control 9th, Phitsanulok, Tonga; Ministry of Public Health had initiated the project. NATIONAL ACCESS TO ANTIRETROVIRAL FOR PHA PROGRAMME to help the patients to access to antiretroviral drug equally. In region 9, it started on October 2002. This study aim to evaluate early clinical outcome of the patients in this project. We have included the patient
PMTCT in Rwanda: knowledge, attitudes, and practices of healthcare providers.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12613); Jean-Baptiste R;;;; University Research Co. LLC, Bethesda, MD, United States; Little empirical evidence is available that describes providers attitudes, and practices towards HIV+ pregnant women. We aimed to deepen our understanding of these largely anecdotal reports, and of the challenges facing experienced HIV clinicians in Rwanda . Methodology: Six focus groups were conducted usin
The symptom experience of people living with HIV/AIDS in Southrn Africa.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12617); Makoae LN, Seboni NM, Molosiwa K, Moleko M, Human SP, Sukati NA, Holzemer WL;;;; National University of Lesotho, Maseru, Lesotho; The symptom experience is described in a purposive, convenience sample of 743 men and women living in their communities with HIV/AIDS in Botswana , Lesotho , South Africa and Swaziland . Data was collected in 2002 using a cross-sectional design.
Developing a Curriculum on HIV Prevention and Treatment for Caregivers in Resource-Limited Countries: The experience of WHARF in Mumbai, India.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12621); Makadon HJ, Jerajani H, Batura D, Menon MS, Setia MS, Fuller J, Libman H;;;; Wockhardt HMI HIV/AIDS Education and Research Foundation (WHARF), Mumbai, India; Recognizing the importance of becoming more actively involved in HIV/AIDS prevention and treatment efforts, health care providers in India have identified the need for appropriate education. Despite the growing availability of low cost medications, including antiretroviral therapy, guidelines from the governmen
Comparison of COBAS Amplicor HIV-1 Monitor Test v. 1.5; manual samples preparation protocol with COBAS AmpliPrep®/COBAS Amplicor HIV-1 Monitor Test v. 1.5.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12625); Likanonsakul S, Uttayamakul S, Kanummorn Y, Sriinkaew A, Pinyowiwat V, Chaovavanich A;;;; Bamrasnaradura Infectious Disease Institute, Nonthaburi, Thailand; COBAS AMPLICOR system has played a major role in routine molecular diagnostics in Thailand since 1997. Now COBAS AmpliPrep® machine has been introduced in October 2002 and used for automated specimen preparation followed by COBAS Amplicor for amplification and detection process. We compared
Motivating staff for PMTCT through comprehensive training: The Tanzania experience.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12629); Msuya G, Msaky H, Reeler A, Kironde S, Nzima M, Munisi W, Manumbu C, Ntyangiri E, Wilfert C;;;; Hai District Council, Hai, Tanzania; Traditionally, delivery of PMTCT has been confined to highly qualified medical staff due to the fact that it requires delicate handling of clients, HIV testing and the usage of new drugs. However, most health facilities in developing countries like Tanzania are faced with a shortage of such staff which makes de
Health Care Providers and their perception of PLWAs: views of person living with HIV.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12633); Ihembeto V, Matemilola PO;;;; Federal Medical Center, Makurdi, Nigeria; The HIV pandemic is already well established and the Nigerian epidemic continues to grow as elsewhere in the world despite our responses. Health care facilities are often the first point of contact for persons who test positive to HIV. Rather unfortunately the worst forms of stigma emanates from these very inst
Optimal HAART in pregnant women with multi-drug resistant virus.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12637); Gilmore J, Kostman JR;;;; University of Pa Health System/Presbyterian, Philadelphia, United States; Current guidelines recommend the use of resistance testing (RT) in pregnant women as per guidelines for other HIV-infected individuals. Optimization of antiretroviral therapy in pregnant women with extensive treatment history and drug resistance is imperative in order to maintain HIV viral load as low as po
Teaching patients about HIV/AIDS and ART in Malawi- The IEC strategy at Lighthouse Clinic and patient understandings of ART.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12645); Neuhann F, Makwiza I, Chiunguzeni D, Lalloo D, Kemp J;;;; Lighthouse, Lilongwe, Malawi; . The current momentum to increase access to ART in countries like Malawi requires appropriate communication with patients about the chronic treatment of HIV infection, in order to achieve high adherence rates for good immunological and virological outcome. Patients concepts of the disease may be very divergent
Use of antiretroviral therapy among HIV-seropositive patients attended at a public reference hospital in Peru.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12649); Verdonck K, Vidal M, Seas C, Echevarria J, Maguina C, Gotuzzo E;;;; Prince Leopold Institute of Tropical Medicine, Antwerp, Belgium; In the near future, there will be free access to antiretroviral (ARV) therapy within the Peruvian public health system, where the majority of HIV-positive patients are attended. The objective of the study is to describe the use of ARVs in a large public hospital before these drugs are made available for fre
Herpes Zoster amongst HIV patients of Rajasthan, India: frequency, manifestations and complications.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12653); Garg DK, Purohit SD, Negi R, Haag A, Mora C, Purohit V;;;; FXB Rajasthan Society, Jodhpur, India; Herpes zoster (HZ) or shingles, represents reactivation of previous infection with Varicella-zoster virus. Patients with HIV may have more frequent, severe, multidermatomal and prolonged episodes and recurrences of shingles, than the general population. Recurrent and multi-dermatomal zoster are considered c
Indian traditional therapy use among HIV seropositive patients in Chennai, India.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12657); Bhakta N, Macalino GE, Akileswaran C, Mayer K, Kumarasamy N, Solomon S;;;; Brown University, Providence, RI, United States; We investigated the use of Indian traditional therapies (TT) among HIV-positive patients who attend Y. R. G. Centre for AIDS Research and Education (CARE) in Chennai, India. Methods: A cross-sectional survey was administered to a sample of 429 HIV positive patients over a one-month period. Results: Of 429 p
Acquired free protein S (PS) deficiency in HIV-infected patients is connected with the levels of the lipid profile.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12661); Peres SD, de Larranaga GF, Lucero A, Alonso BS, Puga L, Benetucci JA;;;; Hemostasis and Thrombosis Laboratory, Hospital of Infectious Diseases F. J. Muniz, Buenos Aires, Argentina; PS, bound to protein and free, is a physiological anticoagulant and its deficiency is associated to increased risk of thrombosis. Acquired PS deficiency has been described in HIV+ although little is known about its mechanism and clinical implication. We evaluated the levels of plasma PS in 26 HIV+ before (N
Community volunteer assisted health education to prevent mother-to-child transmission of HIV in Zimbabwe.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12665); Munhenga A, Marangwanda C, Wells J, Moyo S, Chirapa E, Maldonado Y, Chipato T, Shetty A;;;; UZ-UCSF Collaborative Research Programme, Harare, Zimbabwe; Prevention of Mother to Child transmission of HIV (PMTCT) is an important public health issue in Zimbabwe . Given the current economic hardships, one of the major barriers to the success of PMTCT programs is shortage of nursing staff. Clinics often have 2 or 3 nurses who are responsible for all clinic services,
HIV RT-PCR RNA (viral load) as a surrogate marker for infection in children from 2 to 24 months age born seropositive mothers.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12669); Rossini MA, Santos IM, Campos NC;;;; Adolfo Lutz Institute, Sao Paulo, Brazil; Diagnosis of HIV infection in children is based on persistence of anti-HIV-1 antibodies at 18 months of age associated with positive HIV-1 culture or polymerase chain reaction (in two separate samples) or presence of clinical symptoms of aids. In Brazil , the official procedure to certify HIV-infection in c
Integrating ART into health systems across a continuum of care for PLHA in Kenya, Rwanda and Ghana.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12673); van Praag EV, Kwasi JA, Ngabonziza MN, Stuart MS, Field ML, Mukadi YD;;;; Family Health International, Arlington, VA, United States; The effort to move to nationwide access to ARV medication in least resourced countries has lead to an unprecedented obligation of resources through multiple global and bilateral mechanisms. Commitment by politicians and public health authorities has resulted in strategic planning to make this happen. Scale up o
HIV/AIDS and us mob.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12677); Costello M;;;; Australian Federation of AIDS Organisations, Sydney, Australia; Reported rates in Australia of HIV and AIDS diagnoses per capita are similar between Indigenous and non-Indigenous peoples. The most frequently reported route of transmission is male homosexual contact. However there are a higher proportion of heterosexually acquired cases of HIV in Indigenous populations than non-Indi
Needs Assessment and Identification of Alternatives for the Implementation of a National HIV Antirretroviral Program: The Peru HAART Study.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12681); Caceres CF, Lopez R, Pichihua J, Mendoza W, Avila C, Pajuelo J, Valverde R, Cuellar L, Rosasco A, Salazar X, Gutierrez J;;;; Cayetano Heredia University, Lima, Peru; In a global context favoring access to highly active antirretroviral treatment (HAART) among those in need, a study was convened to assist the Ministry of Health of Peru to: (1) assess the epidemiological, social, political, economic, health-systems (services, drug access) and legal aspects of the current H
Tenofovir DF therapy for chronic Hepatitis B in HIV positive patients.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12685); Harris M, Montessori V, Sherlock C, Guillemi S, Toulson A, Chan K, Merrick L, Montaner J;;;; BC Centre for Excellence in HIV/AIDS, Vancouver, Canada; With the advent of highly active antiretroviral therapy and improved survival in HIV infected patients, coinfection with viral hepatitis has emerged as a significant health threat. Treatment of Hepatitis B (HBV) has been limited to lamivudine or interferon alpha, but neither of these has been successful in
A singlecentre six-month clinical experience of atazanavir in a Special Access Scheme (SAS) in Australia.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12689); Gold J, Sarangapany J, Kelly M, Bridle S;;;; Albion Street Centre, Sydney, Australia; Clinical trials have demonstrated atazanavir (AZV) to be potent, safe and well tolerated in both naive and treatment experienced patients. However, little is known about how this drug performs in a clinic setting. This audit was performed to correlate our experience with published reports.
Efavirenz Plasma Concentrations - is gender important?: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12693); Pereira SA, Corte-Real RM, Branco T, Germano I, Lampreia F, Caixas U, Monteiro EC;;;; Department of Pharmacology, Faculty of Medical Sciences, New University of Lisbon, Lisbon, Portugal; Recent data point to the importance of gender-related differences in antiretroviral pharmacokinetics. High efavirenz (EFV) plasma concentrations (Cps) found in women could be related to differences in body mass index (BMI), age and sampling time. The aim of the present work was to establish a comparison bet
The value of observational HIV patient data for the evaluation of antiretroviral therapy: problems and successes.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12697); Anderson RM, Donnelly CA;;;; Imperial College London, London, United Kingdom; Background : Observational clinical cohort studies are increasingly used to evaluate treatment of HIV infection since randomised clinical trials (RCTs) are unable to keep up with the rate of emergence of new combinations of antiretroviral agents (ARVs) and treatment strategies. Longer-term outcomes of ARV therapy (both
ARV selection criteria and innovative group adherence counseling in Bukavu, Democratic Republic of Congo - program implementation in the context of chronic war and a failing healthcare system.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12702); Tu D, Kos N, Culbert H, Migabo K, Amisi T;;;; MSF Holland, Amsterdam, Netherlands; Adherence to ARV medications is paramount to effective therapy. The city of Bukavu, like other cities in the DRC, exists in an environment of chronic conflict and recurrent episodes of humanitarian crisis. This has resulted in the near collapse of most social structures, including healthcare. Risk factors for t
Evaluation of antiretroviral treatment in Fort Portal, western Uganda.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12706); Karcher H, Moses A, Weide AL, Stelzenmueller J, Mayer A, Harms G;;;; German Technical Cooperation (GTZ), PMTCT Coordination Office Berlin, Berlin, Germany, Berlin, Germany; Antiretroviral treatment for pregnant women and their families was introduced as part of a GTZ-supported PMTCT Plus Programme in rural western Uganda . We assessed treatment response, toxicity and adherence in 76 patients, 41 women, 30 men and 5 children. Methods: The standard regimen was Zidovudine,
Mycobacterium tuberculosis strains within a South African high HIV prevalence community.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12711); Middelkoop K, Whitelaw A, Ntutela C, Vogt M, Kreiswirth B, Wood R, Bekker LG;;;; Desmond Tutu HIV Centre, Cape Town, South Africa; In Masiphumelele, Cape Town, TB rates are high (1684/100K in 2001), despite an effective community TB control program (treatment completion rates of 85-90%). The HIV epidemic (prevalence of 20-30%) is believed to be undermining the TB Control Program. Utilising molecular epidemiology to identify and monitor
Relationship of phase of the menstrual cycle to HAART related symptoms and adherence.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12715); Grimes RM, Patel P;;;; The University of Texas Health Science Center at Houston, Houston Texas, United States; OBJECTIVES: The study sought 1) to identify the symptoms that HIV positive women on HAART experience during three phases of their menstrual cycles, 2) to see if adherence to medications varies through the menstrual cycle and 3) to measure if the symptoms experienced during the menstrual cycle are associated with adhere
How prepared are public health clinics in Blantyre, Malawi to offer services for against vertical transmission of HIV?: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12719); Muula AS;;;; Department of Community Health, University of Malawi College of Medicine, Blantyre, Malawi; Malawi has at least 10% of its population infected by HIV. Currently, there are plans to provide widespread antiretroviral therapy to prevent mother to child transmission of HIV. The study aimed to describe perceptions of midwives towards selected issues regarding mother to child transmission of HIV in elev
Lymphocyte Homeostasis in HIV-Infected Northern Thais.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12723); Nelson KE, Kingkeow D, Heilig CM, Suriyanon V, Rungruenthanaki K, Costello C, Duerr A;;;; Johns Hopkins University, Baltimore, United States; Studies of HIV-1 infected persons from developed western countries mostly infected with subtype B viruses have shown that loss of T-lymphocyte homeostasis occurs 1.5-2.0 years prior to AIDS. However, lymphocyte dynamics have not reported from developing country populations, especially Thais infected with su
Changes in markers of Hepatic functions in HIV infected subjects co-infected with HBV after triple RTI therapy.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12727); Idigbe EO, Akanmu AS, Audu RA, Adewole TA, Onwujekwe DI, Musa AZ, Oparaugo CT, Lemoha E, Odunaike MI;;;; Nigerian Institute of Medical Research, Yaba-Lagos, Nigeria; In HIV infected persons who are co-infected with HBV, immune reconstitution following ARV therapy is known to worsen cytotoxicity of HBV on hepatocytes. This study was carried out to determine changes, if any, in hepatic functions in HIV infected patients co-infected with HBV after 24 weeks of therapy with
Reducing mother to child HIV transmission: a successful experience.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12731); Carvalho PB, Maerrawi IE, Anselmo L, Oliveira MA, Nascimento I, Gomes RB, Theodosio SB, Soares MS, Duarte M, Duarte BR, Sarmento WC, Khater JF, Lima JR;;;; Secretary Health Sao Vicente, Sao Vicente, Brazil; Sao Vicente City, Sao Paulo State, Brazil is the 22nd city in incidence of notified AIDS cases in Brazil. Following the tendency of the AIDS epidemic in our country, Sao Vicente presents more and more women becoming HIV infected, in a proportion of one men to each women. As a result, the STD/AIDS Program has bee
The experience of caregivers of patients with symptoms of AIDS in resource poor communities: The case of Malawi.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12736); Chimwaza AF;;;; University of Malawi, Kamuzu College of Nursing, Blantyre, Malawi; The AIDS epidemic is negatively affecting the health care system of Malawi because of the increased number of patients who require long-term care. Provision of hospital care is difficult because of inadequate space, material and human resources. Consequently, most patients with AIDS are given care at home.
Evaluating the effectiveness of inter-personal communication training for PMTCT with health care professionals in Namibia: programmatic implications.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12740); Howson JF, Murray-Johnson L, Englebrecht S, McSmith D, Witte K;;;; Health Communication Partnership, Baltimore, United States; Discussion of PMTCT, and subsequent enrolment of pregnant women by health care providers at 5 Namibian mission hospitals was limited by their perceived lack of confidence and skills in being able to manage this process. We offered a 5 half-day training course to improve their inter-personal communication (I
Acceptance and adherence for hepatitis B immunization among injecting drug users (IDUs) in Bangkok narcotic treatment clinics: preparation for future HIV vaccines.: Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B12744); Sunthornchart S, Vinmutsuthorn A, Netpianvanit V, Maneesinthu K, Trairat N, Donchalermpak S, Subhachaturas W, Virapat P, Supawitkul S, Vitek C, Levine WC, Tappero JW;;;; Department of Health, Bangkok Metropolitan Administration (BMA), Bangkok, Thailand; Narcotic treatment clinics for IDUs in Bangkok may be an appropriate setting for preventive immunization because this population regularly accesses services that facilitate follow-up. In addition, an immunization program for a high prevalence infection, such as hepatitis B , may si

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