AEGiS-15IAC: Risk of HIV transmission through "SCREENED" blood transfusion in Nigeria.

15th International AIDS Conference

Bangkok, Thailand - July 11-16, 2004

Risk of HIV transmission through "SCREENED" blood transfusion in Nigeria.

Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. C10092)

Odunukwe NN, Njoku SO, Nnodu O, Amusu AO
Nigerian Instituteof Medical Research and Nigeria Army Base Hospital, Yaba Lagos, Nigeria

BACKGROUND: It has been established that HIV transmission is possible through blood transfusion in Borno state Nigeria. Blood transfusion in medicine is indispensable and since it is inevitable, blood of infected but sero-negative donors may still be transfused. The work is aimed at evaluating the risk of HIV transmission through transfusion of sero-negative infected blood. Materials and

METHODS: Fifty-five healthy blood donors and adult coming for routine medical exam at military hospital Yaba Lagos Nigeria who gave their consent were studied. Blood samples were collected screened using four different rapid antibody screening kits and the results obtained were confirmed with western blot.

RESULT: The result revealed that 90% of the samples screened with Gene II were negative, only 2% and 8% not done. Screening with Immunocomb, 73.1% negative, 11.5% positive and 15.4% not done. Gen screen gave 6% negative, 65% positive and 29% not done. Determine 31% negative and 69% positive. Western blot revealed 13% negative and 87% positive.

CONCLUSION: It is concluded that blood transfusion with the present screening methods in Nigeria is very risky. We suggest that before blood will certified fit for transfusion it must have tested negative with Gen screen, Western blot or PCR.

Keywords: AEGIS, Acquired Immunodeficiency Syndrome, HIV Seropositivity, Blood Transfusion, Blood Donors, Blood Banks, Mass Screening, AIDS Serodiagnosis, Blotting, Western, Hematologic Tests, Polymerase Chain Reaction, Nigeria, Adult, transmission, blood, diagnosis, instrumentation

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C10092