AEGiS-14IAC: Mortality and burden of disease in a cohort of HIV seropositive adults in Nairobi, Kenya.

14th International AIDS Conference


Barcelona, Spain - July 7-12, 2002

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Mortality and burden of disease in a cohort of HIV seropositive adults in Nairobi, Kenya.

Int Conf AIDS 2002 Jul 7-12; 14:(abstract no. C10665)

Shepherd BE, Mwachari CW, Cleopa O, Odhiambo JA, Cohen CR
Universtity of Washington, Seattle, United States

BACKGROUND: Few studies have longitudinally investigated the spectrum of opportunistic diseases among HIV-infected individuals in sub-Saharan Africa.

METHODS: In this study a cohort of 381 seropositive ambulatory adults in Nairobi, Kenya was followed from 1997 to 2000 with participants visiting the clinic every 2 months and when acutely ill. The incidences of clinical diagnoses were reported.

RESULTS: Acute bronchitis was the most frequent manifestation, followed by sexually transmitted infections, candida vaginitis (among women), fever, diarrhea, pneumonia, folliculitis, oral candidiasis and urinary tract infection. Associations between the frequency of these diagnoses and initial CD4 count, age, gender, marital status, and education were examined. Risk factors associated with survival were also investigated. A low CD4 count at recruitment was associated with decreased survival and a higher incidence of sexually transmitted infections, pneumonia, folliculitis, oral candidiasis and diarrhea.

CONCLUSIONS: This information might prove useful to determine where to best allocate resources to improve lives of HIV-infected individuals in sub-Saharan Africa.

Keywords: AEGIS, HIV Seropositivity, CD4 Lymphocyte Count, HIV Infections, Risk Factors, Incidence, Marital Status, Pneumonia, Survival Rate, Kenya, Africa South of the Sahara, Adult, Human, Female, mortality, EpidemiologyKWDaegis,hivseropositivity,cd4lymphocytecount,hivinfections,riskfactors,incidence,maritalstatus,pneumonia,survivalrate,kenya,africasouthofthesahara,adult,human,female,mortality,epidemiology

020707
C10665

Copyright © 2002 - International AIDS Society (IAS). Reproduction of this abstract (other than one copy for personal reference) must be cleared through the IAS.