AEGiS-14IAC: Disseminated bacille calmette guerin (BCG) infection in Argentine AIDS children.

14th International AIDS Conference


Barcelona, Spain - July 7-12, 2002

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Disseminated bacille calmette guerin (BCG) infection in Argentine AIDS children.

Int Conf AIDS 2002 Jul 7-12; 14:(abstract no. B10223)

Sardi FM, Casanueva EV, Moreno R, Barboni G, Gregorio G, Gazpio M
Argentine pediatric asociation, Buenos Aires, Argentina

BACKGROUND: In Argentina BCG vaccination is obligatory at birth. In other colaborative study presented in this Congress, we found disseminated BCG infection in 6 / 656 aids children.

METHODS: We present 6 patients with disseminated BCG and aids, who received the vaccine before HIV diagnosis.

RESULTS: The average age was 9 months. 5 of them were in C3 status due to CDC Classification, and only 1 was in C2 status. Regional lynphadenitis, hepatoesplenomegaly and persistent fever were the main sings and symptoms. Wasting syndrome was found in 3 patients, severe anaemia in 2 and hepatitis in 2. The BCG was isolated from axilar adenopathy, blood, bone marrow, stool and liver biopsy. None of them received pirazinamida but also all were treated with antiretroviral drugs. Mortality average was 50%.

CONCLUSION: Disseminated BCG infection has relationship with inmunological status in aids children.

Keywords: AEGIS, Mycobacterium bovis, Acquired Immunodeficiency Syndrome, Infection, BCG Vaccine, AIDS-Related Opportunistic Infections, Vaccination, Opportunistic Infections, Centers for Disease Control and Prevention (U.S.), Congresses, Vaccines, Bacteremia, Cause of Death, Argentina, United States, Child, HumanKWDaegis,mycobacteriumbovis,acquiredimmunodeficiencysyndrome,infection,bcgvaccine,aids-relatedopportunisticinfections,vaccination,opportunisticinfections,centersfordiseasecontrolandprevention(uKWDsKWD),congresses,vaccines,bacteremia,causeofdeath,argentina,unitedstates,child,human

020707
B10223

Copyright © 2002 - International AIDS Society (IAS). Reproduction of this abstract (other than one copy for personal reference) must be cleared through the IAS.