AEGiS-11IAC: Hepatitis C prevalence and incidence in a cohort of HIV+ and HIV- female prisoners.

11th International AIDS Conference


Vancouver, British Columbia — July 7-12, 1996

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Hepatitis C prevalence and incidence in a cohort of HIV+ and HIV- female prisoners.

Int Conf AIDS 1996 Jul 7-12; 11:378 (abstract no. Tu.C.2655)
Fennie KP, Selwyn PA, Stephens PC, Balacos K, Altice FL; Yale University AIDS Program, New Haven, CT, USA. Fax: (203) 737-4051. E-mail: KFennie@yale.edu.

OBJECTIVE: To examine the prevalence, incidence and risk factors for Hepatitis C (HCV) and its relationship to HIV infection in female prisoners, at Connecticut's sole intake facility for women.

METHODS: Anonymous HCV seroprevalence (P)/Incidence (I) study using discard sera obtained on admission, and linked anonymously to medical, clinical, and behavioral data obtained from routine intake. Assignment of serial study numbers and separation of clinical/serologic testing sites, allowed repeat sampling and linkage of clinical/serologic data while preserving anonymity of data. Subjects included: 1) random sample; 2) IDUs; and 3) non-IDUs who reported sex with IDU (SxHx). HCV incidence calculated on readmission of those initially HCV-. (table: see text)

RESULTS: In the random sample, IDU was the only significant risk factor for HCV (p is less than .05); HIV, sexual behavior, and race were not significant. In the IDU/SxHx populations, HIV was a risk factor for HCV (OR 11.3, 95%CI 3.7-37.9) During a 1 yr followup, 3/13 HCV- IDUs became HCV+: I=52/100 person years.

CONCLUSIONS: This study demonstrates a high prevalence of HIV and HCV in female prisoners (HCV greater than HIV), both in IDUs and sex partners of IDUs. Preliminary data suggest high HCV incidence in at risk IDUs, thus emphasizing the importance for clinical care and risk reduction interventions for high risk women entering a correctional setting.

Keywords: AEGIS, Incidence, Prevalence, Hepatitis C, Hepacivirus, HIV Infections, Hepatitis C Antibodies, Seroepidemiologic Studies, Risk Factors, Risk, Connecticut, Human, Female, epidemiology, ICA11KWDaegis,incidence,prevalence,hepatitisc,hepacivirus,hivinfections,hepatitiscantibodies,seroepidemiologicstudies,riskfactors,risk,connecticut,human,female,epidemiology,ica11

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TuC2655

Copyright © 1996 - International AIDS Society (IAS). Reproduction of this abstract (other than one copy for personal reference) must be cleared through the IAS.