2nd International AIDS Conference

Paris, France - 1986

Cited as: Int Conf AIDS. 1986 June 23-25;2: Abstract No.

SESSION D'OUVERTURE / OPENING SESSION
SP	WORLD HEALTH ORGANIZATION'S PROGRAMME ON AIDS Int Conf AIDS 1986 Jun 23-24; 2:5 (abstract no. SP) H. Mahler, F. Assaad The WHO programme on AIDS was submitted to the 77th Executive Board of the World Health Organization in January 1986. The subject was discussed in depth and a resolution was passed urging Member States to maintain vigilance, to share information in all openness with WHO and to cooperate in developing public health strategies for the prevention and control of LAV/HTLV-III infection. The Director-General was called upon to further develop the activities established within the WHO programme on AIDS and to seek additional extra budgetary funding for the support of national and collective programmes.
SESSION PLENIERE / PLENARY SESSION I
SP1	THE AIDS RETROVIRUS : AN UPDATE Int Conf AIDS 1986 Jun 23-24; 2:5 (abstract no. SP1) Luc Montagnier The exact role of LAV_S in AIDS pathogenesis remains to be elucidated. The mechanism leading to a progressive and irreversible destruction of the T4 cell population remains is complex and is likely to be indirectly caused by the viral infection.
SP3	AIDS IN AFRICA Int Conf AIDS 1986 Jun 23-24; 2:5 (abstract no. SP2) B.M. Kapita The first cases of AIDS in Africans were confirmed in Europe in 1981 and in Africa in 1983. At present, the epidemiology of AIDS in Africa is unclear, due to marked variations in surveillance effort and in reporting of cases. Nevertheless, it is clear that LAV/HTLV-III has established itself solidly in Africa.
SESSION PLENIERE / PLENARY SESSION II
SP4	VARIATION IN AIDS RELATED ILLNESSES: IMPACT ON CLINICAL RESEARCH Int Conf AIDS 1986 Jun 23-24; 2:5 (abstract no. SP4) P. Volberding, M.D. Variations in clinical AIDS effect resources needed for patient care and on clinical trials design. In AIDS related dementia, the need for long term institutional care may increase dramatically, if this manifestation becomes more common. Clinical variations in AIDS are also important as clinical research results may be misleading if not carefully adjusted to the study population. Also, clinical changes make the use of historical control groups problematic. It is hoped that changes in the clinical spectrum of AIDS may offer new insights into the biology of the AIDS virus and the human host defense system.
SP5	LAV-HTLV III INFECTION IN INFANTS AND CHILDREN Int Conf AIDS 1986 Jun 23-24; 2:5 (abstract no. SP5) Claude Griscelli The number of reported cases of AIDS in children reachs 200 in the USA and the 60 cases in Europe represent 2,8% of AIDS. More than 5 times these numbers correspond to other expression of LAV-HTLV-III infection. The main risk factor for children was transfusion of blood products and transmission of the virus from mother to child, firstly described in Haitian or Zairian families, now represents the highest risk factor in an infant born from drug addicted mother.
SP6	THE CLINICAL LABORATORY IN THE DIAGNOSIS AND MANAGEMENT OF AIDS AND HTLV-III/LAV INFECTIONS Int Conf AIDS 1986 Jun 23-24; 2:5 (abstract no. SP6) Michael S. Gottlieb and John L. Fahey Acquired immune deficiency syndrome (AIDS), the AIDS prodrome, HTLV-III/LAV chronic lymphadenopathy, and acute HTLV-III/LAV infection are encountered with increasing frequency in clinical practice. Essential points of the medical history include increased relative risk of contracting HTLV-III/LAV including a history of sexual contact and/or shared needle use with risk groups. Historical clues for AIDS should be sought as a component of the complete medical evaluation in endemic areas.
S1-VIROLOGIE / VIROLOGY : 1
SP7	THE PHYSIOPATHOLOGY OF LAV/HTVL-III: A COMPLEX PATHWAY OF HOST-VIRUS INTERACTION Int Conf AIDS 1986 Jun 23-24; 2:6 (abstract no. SP7) David Klatzmann, J.C. Gluckman Once established evolution of LAV infection depends mainly on three factors: (1) The virus tropism will determine its target cells and organs. Among T lymphocytes, CD8 cells are completely resistant to infection while CD4⁺ cells are highly susceptible because the crucial role of the CD4 molecule in controlling virus binding and its subsequent penetration into CD4⁺ cells.
373	EVIDENCE OF LAV/HTLV III INFECTION, AND AIDS-RELATED COMPLEX IN LAGOS, NIGERIA Int Conf AIDS 1986 Jun 23-24; 2:129 (abstract no. 373) A. NASIDI¹, T.O. HARRY¹, O.O. AJOSE-COKER², S.A. ADEMULUYI² and O.O. AKINYANJU² Our findings indicate that LAV/HTLV III infection is present in Lagos, Nigeria, both in patients and in healthy individuals , and that blood transfusion is a route of transmission of the virus in the area.

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