9TH EUROPEAN AIDS CONFERENCE (EACS) 1st EACS RESISTANCE & PHARMACOLOGY WORKSHOP October 25 - 29, 2003 Warsaw • Poland

Background of Study: STDs increase risk of HIV. HIV/PWA suffer STDs more frequently than population. Syphilis ( 3.0/100 000), gonorrhea (1.6/100 000) and warts were the most frequent STDs in Poland in year 2002.

Objectives: To assess prevalence of STD co-infection in sub-populations of HIV+ patients. To determine prevalence of oncogenic human papilloma virus types among HIV+ women.

Methods: In 1990-2002 we observed 1968 patients (474 women, 1494 men). Among them 1386 idu's, 329 heterosexual, 253 homo/bisexual. VDRL, FTA-ABS or TPHA were used for syphillis and microscopic finding and culture for gonorrhea. Warts were diagnosed by clinical examinations. Genital swabs were collected from 122 women and tested with Hybrid Capture II for high risk types (HR-HPV).

Results: We recognised STDs among 8,6% women and 14,0% men. Syphilis was diagnosed in 12,5 %, gonorrhoea in 2,9% and warts 11,7%. In men highest ratio we found in homosexual group (40,7%), the lowest in idu's ( 8,5%). In women was no difference between heterosexual and idu's ( 7,9% and 8,8% respectively). Warts were detected in 5,5% of women and 13,7% men. In men highest freguency 44,6% was in homo/bisexual group and lowest in idu's (5,9%), among women 6,0% in idu's and 3,5% in heterosexual. Oncogenic HPV types were prevalent (51,6%). No association between high-risk HPV and CD4 count was found.

Conclusions: STDs are significantly more frequent in HIV+ than in general population. HIV+ women are at high risk for cervical cancer and should be screened regardless of immune status.

Presenting Author: PhD Ewa Firlag-Burkacka, Hospital of Infectious Diseases, AIDS Diagnosis&Therapy Center, Warsaw, Poland, 37 Wolska Str., 01-201, Warsaw, Poland, Phone: +48 22 632 06 11

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