14th Annual Conference of the British HIV Association 23-25 April 2008, Belfast

THE PREVALENCE OF VIRAL SUPPRESSION IN HIV PATIENTS ON ART AT A DISTRICT GENERAL HOSPITAL

HIV Med 2008 Apr 23-25 (Suppl 1);14:15 (abstract no. P20)

M Sethupathi, W Simukonda, K Yoganathan and C Williams
Singleton Hospital, Swansea NHS Trust, Swansea, UK

BACKGROUND: The goal of antiretroviral therapy (ART) is to achieve viral suppression which is an important prognostic marker in an HIV disease. Several studies reported viral suppression varying from 55% to 95% and decreases with time. The primary objective is to find out the prevalence of viral suppression at this centre. The secondary objectives are to find out the common combination of ART used and the duration of viral suppression.

METHOD: A retrospective study of HIV patients who attended at this centre till December 2007, was assessed for the prevalence of viral suppression (<400 copies) after being on ART for >3 months since1996.

RESULT: This study identified 249 patients. 171 (68.6%) patients were on ART for >3 months. 123 patients were on first line, 45 on second line and three on salvage (>4 ART) treatment. 161 (94.1%) patients achieved viral suppression. Three late presenters died. One developed resistance. Another patient lives abroad and attends infrequently. Five patients stopped treatment on their own accord. 83 (48.5%) patients who achieved viral suppression were on ART for >5 years. 95 (55.5%) patients were on abacavir and lamivudine twice a day regimen. One twenty (70%) patients were on NNRTI regimens and 51 patients (30%) were on PI based regimens and 44 (86.2%) of those were on atazanavir.

CONCLUSIONS: Our study demonstrated a high prevalence (94.1%) of viral suppression. The most common NRTI backbone was abacavir and lamivudine twice a day and combined mainly with NNRTI. The most common PI was atazanavir in our cohort.

2008-04-23
P20

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