Important note: Information in this article was accurate in 2007. The state of the art may have changed since the publication date.



Question:

My son received a letter from the American Red Cross stating that his blood donation was rejected because the ELISA test for HIV came back positive. Additional test results using the WB and Multiplex NAT were "Indeterminate" and "Negative", respectively. He has never had unprotected sex and does not use drugs. He last had sex more than a month ago. He's very picky who he dates.

Please tell me what these blood test results mean. Thank you.

Answer provided by:

Donna Sweet, M.D.
Professor of Internal Medicine
University of Kansas School of Medicine - Wichita


False positives do occur. The ELISA test is set very sensitive to protect the blood pool and can sometimes come back with a false reading. I would suggest that you have him go to his physician and have them do HIV viral testing to confirm or refute whether he is truly positive or negative. This testing actually tests for the amount of virus in the blood and will show if the virus is present.



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