Important note: Information in this article was accurate in 2007. The state of the art may have changed since the publication date. Is AZT, Viramune, Kaletra and Saquinavir a safe combination, why or why not?
The combination is a bit unusual, but I would need to know more about your reasons for asking.
Viramune is usually used along with a reverse transcriptase inhibitor, like Epivir (3TC).
The combination of Kaletra and saquinavir is ok, but [it] suggest[s] to me that your doctor is going by a complicated resistance profile in an experienced patient.
I would have to defer to his knowledge of the individual patient.
On April 14, twenty two years will have passed since being informed of being HIV positive. Having been recommended various mono therapies, dual drug mantanence therapies, and assorted triple drug therapies, the chances of complete viral suppression are non existent. My question remains, is the combination - AZT, Viramune, Kaletra and Saquinavir safe?
I am not asking for a personal recommendation, rather a simple answer to the question of safety.
I can't call the combination "unsafe," in a large sense.
This a combination that would usually be given to a person with a history of multiple drug treatment, and multiple drug resistance mutations.
If you have none of those mutations, I think it's a bit much, but there might be specific reasons to suggest that this is a very good combination, for your individual case, the details of which are unknown to me. I would not use such a combination in a "naive" patient, without drug resistance issues.
I hope this helps.
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