Important note: Information in this article was accurate in 2005. The state of the art may have changed since the publication date.



Question:

Hello there, my girlfriend has found out that she is HIV+ with her viral load at 11000 and her cd4 count at 410. She just went for some more blood work but it will not be back for at least a week or so, but any advice even at this point would be very grateful. After we found out she was positive we discovered now that she is pregnant, about 13 weeks. I would appreciate any advice that you can give us as we would like to have the baby, but we do not want to threaten her life in any way. We will do what is necessary, so that ultimately it is the best choice, but it is very hard to decide what to do with our situation.

Please, any support would help tremendously.
Thank you very much.
Sincerely,
A worried and loving boyfriend

Answer provided by:

Marty Markowitz, M. D.
Clinical Director
Staff Investigator, Aaron Diamond AIDS Research Center
Associate Professor, Rockefeller University


The approach in the US is to use AZT containing PI-based (nelfinavir) HAART after the first trimester...continued through delivery... Mom and the baby get AZT during delivery as per protocol and the baby is treated for 4 weeks thereafter...guidelines are on the DHHS website: http://aidsinfo.nih.gov/guidelines/default_db2.asp?id=66

The mother is then taken off meds and observed post partum with those #s...

If done correctly, the outcome is generally very favorable!



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