Question:

I've grown immune to all the protease[inhibitors] taken orally. My doctor is talking about "Fuzeon" & I believe it's an abdomen injection. Can you tell me what some of the side effects are and if this has to be injected in the abdomen? When I had a DVT, I had the option of sticking my mid-section or the thighs, I chose the thighs cause the other I can't see doing. - thank you

Answer provided by:

Ross Slotten, M.D.
Klein and Slotten Medical Associates
Private Practice in Family Medicine
With a special interest in HIV disease

I wouldn't be afraid to take Fuzeon. Despite the fact that it's an injection, it has very few side effects. The most annoying side effect is a reaction at the site of injection. The site often becomes red, lumpy and irritated, but otherwise is harmless. I wouldn't worry about an increased risk of DVTs, which you've had in the past; you can use your thighs as well as your abdomen to inject the medication into. As for other side effects, I've not witnessed anything serious. It is a well-tolerated medication. Given your broad resistance to PIs, I don't think you have other options at this time, so go for it. I hope it helps you.

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