Periodontopathic bacteria in English HIV-seropositive persons. NLM AIDSLINE Important note: Information in this article was accurate in 2000. The state of the art may have changed since the publication date.

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Periodontopathic bacteria in English HIV-seropositive persons.

AIDS Patient Care STDS. 1999 Jun;13(6):369-74. Unique Identifier : AIDSLINE MED/20301675
Scully C; Porter SR; Mutlu S; Epstein JB; Glover S; Kumar N; Department of Oral Medicine, Eastman Dental Institute, University; of London, England. CScully@eastman.ucl.ac.uk

Abstract: Selected periodontopathic bacteria were sought in 20 HIV-infected English patients and eight noninfected control subjects with similar periodontal status, using highly specific DNA probes. Actinobacillus actinomycetemcomitans (A. a), Porphyromonas gingivalis, Campylobacter rectus, Prevotella intermedia, and Fusobacterium nucleatum were more frequently detected and were found at higher levels in HIV-infected individuals than in controls. Significantly increased levels of Treponema denticola but, in contrast, lower levels of Eikenella corrodens were found in nonbleeding sites of HIV-infected patients compared with controls. The results of the present investigation on English patients suggest a periodontopathogenic role for A. a, P. gingivalis and C. rectus, and possibly P. intermedia and are in general accord with most previously reported data from the United States. Longitudinal studies are now required to determine more precisely the association between periodontopathic microflora, immune competence and periodontal health and disease in HIV-infected persons.
Keywords: CLINICAL TRIAL CONTROLLED CLINICAL TRIAL JOURNAL ARTICLE Adult AIDS-Related Opportunistic Infections/DIAGNOSIS/EPIDEMIOLOGY/ *MICROBIOLOGY Comparative Study Disease Progression England/EPIDEMIOLOGY Female Fungi/*ISOLATION & PURIF Gram-Negative Bacteria/*ISOLATION & PURIF Gram-Positive Bacteria/*ISOLATION & PURIF Human HIV Seropositivity Incidence Male Middle Age Periodontitis/DIAGNOSIS/EPIDEMIOLOGY/*MICROBIOLOGY Risk Factors

KWDclinicaltrialcontrolledclinicaltrialjournalarticleadultaids-relatedopportunisticinfections/diagnosis/epidemiology/KWDmicrobiologycomparativestudydiseaseprogressionengland/epidemiologyfemalefungi/KWDisolation&purifgram-negativebacteria/KWDisolation&purifgram-positivebacteria/KWDisolation&purifhumanhivseropositivityincidencemalemiddleageperiodontitis/diagnosis/epidemiology/KWDmicrobiologyriskfactors
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