A case of adult T-cell lymphoma leukemia with hemophagocytic syndrome. NLM AIDSLINE Important note: Information in this article was accurate in 2000. The state of the art may have changed since the publication date.

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A case of adult T-cell lymphoma leukemia with hemophagocytic syndrome.

J Dermatol. 2000 Apr;27(4):280-3. Unique Identifier : AIDSLINE MED/20284509
Inoue Y; Johno M; Matuoka M; Zushou Y; Ono T; Department of Dermatology, Kumamoto University School of; Medicine, Japan.

Abstract: A 62-year-old Japanese woman was admitted to our clinic with virus-associated hemophagocytic syndrome (VAHS) in subcutaneous adult T-cell lymphoma leukemia (ATLL). Bone marrow aspiration showed hypocellularity, histiocytic hyperplasia, and hemophagocytosis. There was serological evidence of chronic cytomegalovirus (CMV) infection. The hemophagocytic syndrome (HPS) initially improved by some treatments, and the patient later experienced remission several times, but the CMV infection persisted. Most cases of non-tumorous HPS in adults are associated with viral or bacterial infection, and underlying diseases in non-tumorous HPS are mostly blood diseases, especially T-cell lymphoma (1, 2), but ATLL is a rare underlying disease in such cases.
Keywords: JOURNAL ARTICLE Arm Case Report Cheek Chronic Disease Cytomegalovirus Infections/COMPLICATIONS/*DIAGNOSIS Facial Dermatoses/COMPLICATIONS/*DIAGNOSIS Fatal Outcome Female Histiocytosis, Non-Langerhans-Cell/COMPLICATIONS/*DIAGNOSIS Human Immunohistochemistry Leukemia-Lymphoma, T-Cell, Acute, HTLV-I-Associated/COMPLICATIONS/ *DIAGNOSIS Middle Age Skin Diseases, Viral/COMPLICATIONS/*DIAGNOSIS

KWDjournalarticlearmcasereportcheekchronicdiseasecytomegalovirusinfections/complications/KWDdiagnosisfacialdermatoses/complications/KWDdiagnosisfataloutcomefemalehistiocytosis,non-langerhans-cell/complications/KWDdiagnosishumanimmunohistochemistryleukemia-lymphoma,t-cell,acute,htlv-i-associated/complications/KWDdiagnosismiddleageskindiseases,viral/complications/KWDdiagnosis
000930
A0091336

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