High HIV incidence and prevalence among young women in rural South Africa: developing a cohort for intervention trials. NLM AIDSLINE Important note: Information in this article was accurate in 2000. The state of the art may have changed since the publication date.

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High HIV incidence and prevalence among young women in rural South Africa: developing a cohort for intervention trials.

Unique Identifier : AIDSLINE MED/20322602
Wilkinson D; Abdool Karim SS; Williams B; Gouws E


Abstract: OBJECTIVE: To measure prevalence and model incidence of HIV infection. SETTING: 2013 consecutive pregnant women attending public sector antenatal clinics in 1997 in Hlabisa health district, South Africa. Historical seroprevalence data, 1992-1995. METHODS: Serum remaining from syphilis testing was tested anonymously for antibodies to HIV to determine seroprevalence. Two models, allowing for differential mortality between HIV-positive and HIV-negative people, were used. The first used serial seroprevalence data to estimate trends in annual incidence. The second, a maximum likelihood model, took account of changing force of infection and age-dependent risk of
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