Low estimates of HIV seroconversions among clients of a drug treatment clinic in San Francisco, 1995 to 1998.

Important note: Information in this article was accurate in 2000. The state of the art may have changed since the publication date.

Low estimates of HIV seroconversions among clients of a drug treatment clinic in San Francisco, 1995 to 1998.

J Acquir Immune Defic Syndr. 2000 Apr 15;23(5):426-9. Unique Identifier : AIDSLINE MED/20322605
McFarland W; Kellogg TA; Louie B; Murrill C; Katz MH; Department of Public Health, San Francisco, California; 94102-6033, USA. WilliMcFarland@dph.sf.ca.us

Abstract: We estimated HIV incidence among injection drug users attending a drug treatment clinic in San Francisco from 1995 to 1998 using two methods. An anonymous sequential testing method identified no seroconversions among clients seen more than once during the period (one-sided upper 95% confidence limit 1.02 per 100 person-years). A sensitive/less sensitive immunoassay testing strategy detected no early infections (one-sided upper 95% confidence limit 1.90% per year). Methods were concordant and feasible in the setting. Although detection of no new HIV infections in this population of injection drug users (IDUs) is encouraging, epidemiologic studies among IDUs not in treatment are needed to monitor the HIV epidemic effectively.

Keywords: JOURNAL ARTICLE Adult Human HIV Seropositivity/BLOOD/COMPLICATIONS/EPIDEMIOLOGY/*IMMUNOLOGY HIV Seroprevalence HIV-1/*IMMUNOLOGY Incidence San Francisco/EPIDEMIOLOGY Substance Abuse, Intravenous/*COMPLICATIONS/THERAPY Support, U.S. Gov't, P.H.S.
001030
A00A1064

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