Trends in antiretroviral therapy and mother-infant transmission of HIV. The Women and Infants Transmission Study Group. NLM AIDSLINE Important note: Information in this article was accurate in 2000. The state of the art may have changed since the publication date.

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Trends in antiretroviral therapy and mother-infant transmission of HIV. The Women and Infants Transmission Study Group.

J Acquir Immune Defic Syndr. 2000 May 1;24(1):45-7. Unique Identifier : AIDSLINE MED/20334005
Cooper ER; Charurat M; Burns DN; Blattner W; Hoff R; Boston Medical Center, Department of Pediatrics, Boston; University School of Medicine, Massachusetts, USA.


Abstract: Trends in the vertical transmission rate of HIV and evolving antiretroviral usage between 1990 and 1998 within the Women and Infants Transmission Study were evaluated. A decline in mother-infant transmission was temporally associated with advances in therapy, especially when regimens including a protease inhibitor were included in the analysis.
Keywords: JOURNAL ARTICLE Anti-HIV Agents/*THERAPEUTIC USE Disease Transmission, Vertical/*PREVENTION & CONTROL Drug Therapy, Combination Female Human HIV Infections/DRUG THERAPY/*TRANSMISSION HIV Protease Inhibitors/*THERAPEUTIC USE *HIV-1/GENETICS Mothers Pregnancy *Pregnancy Complications, Infectious/DRUG THERAPY Prospective Studies Zidovudine/*THERAPEUTIC USEKWDjournalarticleanti-hivagents/KWDtherapeuticusediseasetransmission,vertical/KWDprevention&controldrugtherapy,combinationfemalehumanhivinfections/drugtherapy/KWDtransmissionhivproteaseinhibitors/KWDtherapeuticuseKWDhiv-1/geneticsmotherspregnancyKWDpregnancycomplications,infectious/drugtherapyprospectivestudieszidovudine/KWDtherapeuticuse
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