Hematospermia as the presenting symptom of metastatic malignant melanoma of unknown primary origin. NLM AIDSLINE Important note: Information in this article was accurate in 2000. The state of the art may have changed since the publication date.

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Hematospermia as the presenting symptom of metastatic malignant melanoma of unknown primary origin.

Urology. 2000 Aug 1;56(2):330. Unique Identifier : AIDSLINE MED/20385372
Meng MV; Werboff LH; Department of Urology, University of California, San Francisco,; School of Medicine, San Francisco, California 94143-0738, USA.

Abstract: The presence of blood in the ejaculate is alarming to patients and may arise from many sources in the genitourinary tract. Fortunately, hematospermia is rarely due to underlying malignancy and only necessitates further evaluation with continued symptoms. We report a case of persistent hematospermia in a man with human immunodeficiency virus caused by metastatic malignant melanoma to both seminal vesicles. The evaluation included pelvic magnetic resonance imaging and transrectal ultrasound-guided biopsy. Metastases to the brain were subsequently discovered, but a primary source for the melanoma could not be identified. This is the first reported case of isolated involvement of the seminal vesicles with malignant melanoma and underscores the potential for serious disease presenting as hematospermia.
Keywords: JOURNAL ARTICLE Adult Biopsy *Blood Case Report Comorbidity CD4 Lymphocyte Count Ejaculation Human HIV Infections/EPIDEMIOLOGY/IMMUNOLOGY Magnetic Resonance Imaging Male Melanoma/EPIDEMIOLOGY/*PATHOLOGY/*SECONDARY Neoplasms, Unknown Primary/DIAGNOSIS/EPIDEMIOLOGY/*PATHOLOGY *Semen Seminal Vesicles/*PATHOLOGY UltrasonographyKWDjournalarticleadultbiopsyKWDbloodcasereportcomorbiditycd4lymphocytecountejaculationhumanhivinfections/epidemiology/immunologymagneticresonanceimagingmalemelanoma/epidemiology/KWDpathology/KWDsecondaryneoplasms,unknownprimary/diagnosis/epidemiology/KWDpathologyKWDsemenseminalvesicles/KWDpathologyultrasonography
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