Verbal working memory in HIV-seropositive drug users. NLM AIDSLINE Important note: Information in this article was accurate in 2000. The state of the art may have changed since the publication date.

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Verbal working memory in HIV-seropositive drug users.

J Int Neuropsychol Soc. 2000 Jul;6(5):548-55. Unique Identifier : AIDSLINE MED/20387846
Farinpour R; Martin EM; Seidenberg M; Pitrak DL; Pursell KJ; Mullane KM; Novak RM; Harrow M; VA Chicago Health Care System-West Side Division, Chicago,; Illinois, USA.

Abstract: Recent evidence suggests that HIV-seropositive drug users are impaired on tasks of visuospatial working memory compared with drug users seronegative for HIV. In the current study we evaluated the performance of 30 HIV-seropositive male drug users and 30 risk-matched seronegative controls on two measures of verbal working memory, the Listening Span and the verbal Self Ordered Pointing Task. Impaired working memory performance was significantly more common among HIV-seropositive persons compared to controls, with the highest incidence of deficit among symptomatic participants. These findings indicate that working memory deficits in persons with HIV are not domain-specific and can be demonstrated reliably in drug users.

Keywords: CLINICAL TRIAL JOURNAL ARTICLE Adult Enzyme-Linked Immunosorbent Assay Human HIV Seropositivity/*PSYCHOLOGY Male Memory, Short-Term/*PHYSIOLOGY Prospective Studies Psychomotor Performance/PHYSIOLOGY Substance-Related Disorders/*PSYCHOLOGY Support, U.S. Gov't, Non-P.H.S. Verbal Learning/*PHYSIOLOGY

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