Important note: Information in this article was accurate in 2000. The state of the art may have changed since the publication date.
[Temporal study in AIDS-associated disease in Brazil, 1980-1999]
Cad Saude Publica. 2000;16(## Suppl 1):21-36. Unique Identifier : AIDSLINE MED/20366510 Guimaraes MD; Departamento de Medicina Preventiva e Social, Faculdade de; Medicina, Universidade Federal de Minas Gerais, Belo Horizonte,; MG, 30130-100, Brasil.
Abstract:
Trends in annual incidence of reported AIDS-associated opportunistic infections (OI/100 adults > 12 years old) among AIDS cases were estimated at the national level in Brazil from 1980 through May 1999. The analysis included chi-square and linear regression modeling. The opportunistic infections included: candidiasis (CD), tuberculosis (TB), Pneumocystis carinii pneumonia (PCP), neurotoxoplasmosis (NT), Kaposi sarcoma (KS), cryptococcal meningitis (CM), and protozoa infections (PI). The overall cumulative incidence rates/100 reported AIDS cases were: CD = 59, TB = 26, PCP = 23, NT = 15, KS = 5, CM = 4, and PI = 4. Annual trends indicated a statistically significant decline in all OIs. However, in the Northeast and Central-West regions there were increases in TB (b = 0.39) and NT (b = 0.20), respectively. TB showed a higher incidence among individuals with less schooling (< 8 years), while PCP and KS had higher incidence rates among those with 8 or more years of schooling, despite similar downward trends. Access to antiretroviral therapy and OI prophylaxis may partially explain these results. However, data reliability, delay in reporting, OI incidence after AIDS, and reporting and diagnostic criteria are factors that also need to be carefully assessed.
Keywords: JOURNAL ARTICLE 1980-1999. Adolescence Adult AIDS-Related Opportunistic Infections/*EPIDEMIOLOGY Brazil/EPIDEMIOLOGY Chi-Square Distribution Disease Notification Educational Status English Abstract Female Human Incidence Linear Models Male Residence Characteristics Retrospective Studies Socioeconomic Factors
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