Evaluation of the quantiplex human immunodeficiency virus type 1 RNA 3.0 assay in a tertiary-care center. NLM AIDSLINE Important note: Information in this article was accurate in 2000. The state of the art may have changed since the publication date.

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Evaluation of the quantiplex human immunodeficiency virus type 1 RNA 3.0 assay in a tertiary-care center.

Clin Diagn Lab Immunol. 2000 Jan;7(1):122-4. Unique Identifier : AIDSLINE MED/20087396
Gale H; Infectious Diseases Section, Medical Service, Veterans Affairs; Medical Center, Washington, D.C 20422, USA.; gale.howard@washington.va.gov


Abstract: The Quantiplex human immunodeficiency virus type 1 RNA 3.0 Assay (bDNA) (Bayer Diagnostics, Walpole, Mass.) produced linear and reproducible (intra-assay and interassay) results over its quantification range of 50 to 500,000 copies/ml of plasma with 96% specificity. A threefold or 0.5-log(10) change or greater was clinically significant for serial patient samples.


Keywords: JOURNAL ARTICLE Ambulatory Care Facilities Comparative Study Glass/CHEMISTRY Human HIV-1/*GENETICS Plastics/CHEMISTRY Reproducibility of Results RNA, Viral/*ANALYSIS Sensitivity and Specificity Specimen Handling/*METHODSKWDjournalarticleambulatorycarefacilitiescomparativestudyglass/chemistryhumanhiv-1/KWDgeneticsplastics/chemistryreproducibilityofresultsrna,viral/KWDanalysissensitivityandspecificityspecimenhandling/KWDmethods
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