Clin Diagn Lab Immunol. 2000 Jan;7(1):125-8. Unique Identifier : AIDSLINE MED/20087397
Hua J; Meyer JD; Lodge JK; Edward A. Doisy Department of Biochemistry and Molecular Biology,; St. Louis University School of Medicine, St. Louis, Missouri; 63104, USA.
Abstract: Cryptococcus neoformans is an opportunistic fungal pathogen that causes meningitis in approximately 10% of patients with AIDS. New selectable markers which confer resistance to G418 or phleomycin when transformed into C. neoformans were made. A hygromycin-selectable marker was modified to allow selection with a single copy of the marker.
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