Will drug resistance testing prove reliable enough to enhance HIV treatments? NLM AIDSLINE Important note: Information in this article was accurate in 2000. The state of the art may have changed since the publication date.

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Will drug resistance testing prove reliable enough to enhance HIV treatments?

Fac Notes. 1998 Nov-Dec;10(6):1-3. Unique Identifier : AIDSLINE AIDS/20700001
Murphy MJ


Abstract: Drug resistance testing is important in evaluating and determining the effectiveness of HIV treatments. Genotypic tests evaluate genetic segments of the virus which correspond to resistance in particular drugs. Phenotypic tests assess the level of drugs needed to stop viral growth. The advantages and disadvantages of both tests are discussed. RNA levels, CD4 counts, and other patient data are still preferred to drug resistance testing as the primary criteria for basing treatment decisions.


Keywords: NEWSLETTER ARTICLE *Drug Resistance, Microbial/GENETICS Drug Therapy, Combination Genes, Viral Genotype HIV Infections/*DRUG THERAPY HIV-1/*DRUG EFFECTS/GENETICS Human Microbial Sensitivity Tests Mutation Phenotype Viral Load

KWDnewsletterarticleKWDdrugresistance,microbial/geneticsdrugtherapy,combinationgenes,viralgenotypehivinfections/KWDdrugtherapyhiv-1/KWDdrugeffects/geneticshumanmicrobialsensitivitytestsmutationphenotypeviralload
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