Understanding the reverse transcriptase inhibitors in HIV. NLM AIDSLINE Important note: Information in this article was accurate in 2000. The state of the art may have changed since the publication date.

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Understanding the reverse transcriptase inhibitors in HIV.

Fac Notes. 1998 Nov-Dec;10(6):13-5. Unique Identifier : AIDSLINE AIDS/20700009
Edmonds-Ogbuokiri J; Xavier University College of Pharmacy, Clinical Pharmacy.


Abstract: Recent progress in treatment methods and medicines has made HIV more manageable. Factors contributing to this progress include advances in testing; the use and approval of protease inhibitors, non-nucleoside reverse transcriptase inhibitors, and other nucleosides; and the success of highly active antiretroviral regimens (HAART) and combination therapy. Nucleoside reverse transcriptase inhibitors, such as Zidovudine and Didanosine, and non-nucleoside reverse transcriptase inhibitors (NNRTIs) such as Nevirapine (Viramune) and Delavirdine (Rescriptor), are recommended for use in combination therapy. The pharmacology, side effects, and contraindications of these types of drugs are provided. Dosages and common side effects are also mentioned.


Keywords: NEWSLETTER ARTICLE Anti-HIV Agents/ADMINISTRATION & DOSAGE/ADVERSE EFFECTS/ *PHARMACOLOGY Drug Therapy, Combination HIV Infections/*DRUG THERAPY Human Reverse Transcriptase Inhibitors/ADMINISTRATION & DOSAGE/ADVERSE EFFECTS/*PHARMACOLOGY

KWDnewsletterarticleanti-hivagents/administration&dosage/adverseeffects/KWDpharmacologydrugtherapy,combinationhivinfections/KWDdrugtherapyhumanreversetranscriptaseinhibitors/administration&dosage/adverseeffects/KWDpharmacology
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