Hepatitis C virus and HIV co-infection: a sleeping giant wakes. NLM AIDSLINE Important note: Information in this article was accurate in 2000. The state of the art may have changed since the publication date.

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Hepatitis C virus and HIV co-infection: a sleeping giant wakes.

Hopkins HIV Rep. 1999 Jan;11(1):3, 10-2. Unique Identifier : AIDSLINE AIDS/20700023
Sulkowski MS

Abstract: Advances in HIV therapy have greatly reduced the incidence of HIV-related complications and mortality, but co-infection with hepatitis C (HCV) virus is becoming more visible. The two infections share transmission routes, with injection drug users and transfusion patients the most commonly infected. Although sexual transmission is less common with HCV, it may be facilitated by an existing HIV infection. Effective HCV treatment strategies are urgently needed for people with HIV because it is leading to notable morbidity and mortality. Trial results of alfa interferon monotherapy are presented. The combination of interferon with Ribavirin also shows promise.

Keywords: NEWSLETTER ARTICLE Antiviral Agents/*THERAPEUTIC USE Disease Progression Drug Therapy, Combination Drugs, Investigational HIV Infections/*COMPLICATIONS Hepatitis C, Chronic/*COMPLICATIONS/*DRUG THERAPY Human Interferon Alfa, Recombinant/*THERAPEUTIC USE Polyethylene Glycols/THERAPEUTIC USE Ribavirin/*THERAPEUTIC USE

KWDnewsletterarticleantiviralagents/KWDtherapeuticusediseaseprogressiondrugtherapy,combinationdrugs,investigationalhivinfections/KWDcomplicationshepatitisc,chronic/KWDcomplications/KWDdrugtherapyhumaninterferonalfa,recombinant/KWDtherapeuticusepolyethyleneglycols/therapeuticuseribavirin/KWDtherapeuticuse
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A0030926

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