Important note: Information in this article was accurate in 2000. The state of the art may have changed since the publication date.
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AIDS Alert. 1999 Feb;14(2):suppl 3-4. Unique Identifier : AIDSLINE AIDS/20700041
Abstract: AIDS vaccines are a long way from being commercially available, however, microbicides may be a viable way to help prevent HIV transmission. In several observational studies microbicides have performed well, but in two controlled studies there was no decrease in infection rates. Nonoxynol-9 (N-9) may be able to kill pathogens such as HIV and other sexually transmitted diseases, although there have been difficulties in administering the right dosage. A low dose is ineffective, and a high dose causes irritation that can leave a woman at higher risk for contracting the disease. Other microbicide products under development are discussed.
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