Important note: Information in this article was accurate in 2000. The state of the art may have changed since the publication date.
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GMHC Treat Issues. 1999 Mar;13(3):12. Unique Identifier : AIDSLINE AIDS/20700067
Gilden D
Abstract: Impotence is often associated with protease inhibitor use, but much of the medical press ignored this issue until Spanish doctors described sexual difficulties following protease inhibitor therapy in 14 of 260 patients. Causes of sexual dysfunction in HIV-infected men are difficult to isolate but may also be traced to depression, physical weakness, opportunistic infections, stress, nerve damage, or hormonal imbalances. Pfizer, the manufacturer of Viagra, released study data on the effects of the drug used in combination with Ritonavir and Saquinavir; the data led Pfizer to alter Viagra dosing recommendations for people on protease inhibitors.
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