Spatial working memory in asymptomatic HIV-infected subjects. NLM AIDSLINE Important note: Information in this article was accurate in 2000. The state of the art may have changed since the publication date.

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Spatial working memory in asymptomatic HIV-infected subjects.

J Neuropsychiatry Clin Neurosci. 1999 Summer;11(3):387-91. Unique Identifier : AIDSLINE MED/99368889
Grassi B; Garghentini G; Campana A; Grassi E; Bertelli S; Cinque P; Epifani M; Lazzarin A; Scarone S; Psychiatric Branch, Centro San Luigi, University of Milan Medical; School, Italy.

Abstract: Many clinical and research findings converge to indicate that frontal lobe, basal ganglia, and related neuronal connections are primarily involved in human immunodeficiency virus (HIV) infection; frontal lobe, mainly the prefrontal cortex, has a specialized role in working memory processes. This study focused on neuropsychological evaluation of the spatial component of working memory in a sample of 34 asymptomatic HIV-infected subjects as compared with 34 age- and sex-matched seronegative control subjects. A computer-administered test assessing spatial working memory was used for the neuropsychological evaluation. The findings did not show any spatial working memory impairment during the asymptomatic phase of HIV infection.

Keywords: JOURNAL ARTICLE Adult Brief Psychiatric Rating Scale Comparative Study Female Frontal Lobe/ANATOMY & HISTOLOGY/PHYSIOPATHOLOGY Human HIV Seropositivity/*COMPLICATIONS/PHYSIOPATHOLOGY Male Memory Disorders/*COMPLICATIONS/DIAGNOSIS/PHYSIOPATHOLOGY Neuropsychological Tests Perceptual Disorders/*COMPLICATIONS/DIAGNOSIS/PHYSIOPATHOLOGY Questionnaires Severity of Illness Index Space Perception/*PHYSIOLOGY

KWDjournalarticleadultbriefpsychiatricratingscalecomparativestudyfemalefrontallobe/anatomy&histology/physiopathologyhumanhivseropositivity/KWDcomplications/physiopathologymalememorydisorders/KWDcomplications/diagnosis/physiopathologyneuropsychologicaltestsperceptualdisorders/KWDcomplications/diagnosis/physiopathologyquestionnairesseverityofillnessindexspaceperception/KWDphysiology
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A0030874

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