Important note: Information in this article was accurate in 2000. The state of the art may have changed since the publication date.
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Br J Dermatol. 1999 May;140(5):919-21. Unique Identifier : AIDSLINE MED/99282224
Holme SA; Lever RS; University Department of Dermatology, Western Infirmary,; Dumbarton Road, Glasgow G11 6NB, U.K.
Abstract: The incidence of positive circulating specific immunoglobulin E (IgE) antibodies to latex and evidence of clinical latex sensitivity appears to be increasing since its first description in 1979. Although heightened medical awareness may be a factor, exposure to latex products, particularly rubber gloves, has increased since the discovery of the human immunodeficiency virus (HIV). Atopic individuals are at greater risk of developing latex sensitivity. We identified seven children with atopic eczema who were known to have clinically significant latex allergy and examined the relationship of prior exposure to latex gloves. All children had significant serum levels of specific IgE to latex. Before developing clinical symptoms of latex allergy, all had been exposed to latex in the form of gloves during either inpatient or outpatient treatments of their skin. Exposure of atopic individuals to latex gloves could be a major risk factor for sensitization and could increase the incidence of serious reactions.
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