[Comparative characteristics of immunoglobulin-synthesizing cell and immunoregulatory T-lymphocyte subpopulation contents in human lymphatic nodes and the spleen] NLM AIDSLINE Important note: Information in this article was accurate in 2000. The state of the art may have changed since the publication date.

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[Comparative characteristics of immunoglobulin-synthesizing cell and immunoregulatory T-lymphocyte subpopulation contents in human lymphatic nodes and the spleen]

Morfologiia. 1998;114(6):47-9. Unique Identifier : AIDSLINE MED/20226698
Pigarevskii PV; N.N. Anichkov Laboratory of Atherosclerosis, Russian Academy of; Medical Sciences, St. Petersburg.

Abstract: The content of lymphocytes producing different classes of immunoglobulins (IgA, IgM and IgG) and immunoregulatory T cell subpopulations (CD3, CD4, CD8) was assessed in structural components of T- and B- zones of lymph nodes of visceral and somatic groups and spleen in man. Forensic autopsy material obtained from 48 men of 2 age groups: 31-60 and 61-75 years was studied. The absence of direct correlation between the quantity of plasma cells in B-zone of peripheral lymphoid organs and their functional activity was shown. The results obtained may serve as an initial point in studying immunomorphological reorganizations of human peripheral lymphoid organs in development of immunopathological processes.

Keywords: JOURNAL ARTICLE immunoglobulinsinteziruiushchikh kletok i immunoreguliatornykh subpopuliatsii T-limfotsitov v limfaticheskikh uzlakh i selezenke cheloveka. Adolescence Adult Aged Antigens, CD3/METABOLISM Antigens, CD4/METABOLISM Comparative Study CD8-Positive T-Lymphocytes/CYTOLOGY English Abstract Human IgA/BIOSYNTHESIS IgG/BIOSYNTHESIS IgM/BIOSYNTHESIS Immunoglobulins/*BIOSYNTHESIS Lymph Nodes/*CYTOLOGY/IMMUNOLOGY/METABOLISM Lymphocyte Count Male Middle Age Spleen/*CYTOLOGY/IMMUNOLOGY/METABOLISM T-Lymphocyte Subsets/*CYTOLOGY/IMMUNOLOGY/METABOLISMKWDjournalarticleimmunoglobulinsinteziruiushchikhkletokiimmunoreguliatornykhsubpopuliatsiit-limfotsitovvlimfaticheskikhuzlakhiselezenkechelovekaKWDadolescenceadultagedantigens,cd3/metabolismantigens,cd4/metabolismcomparativestudycd8-positivet-lymphocytes/cytologyenglishabstracthumaniga/biosynthesisigg/biosynthesisigm/biosynthesisimmunoglobulins/KWDbiosynthesislymphnodes/KWDcytology/immunology/metabolismlymphocytecountmalemiddleagespleen/KWDcytology/immunology/metabolismt-lymphocytesubsets/KWDcytology/immunology/metabolism
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A0071456

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