Relationship between IS901 in the Mycobacterium avium complex strains isolated from birds, animals, humans, and the environment and virulence for poultry. NLM AIDSLINE Important note: Information in this article was accurate in 2000. The state of the art may have changed since the publication date.

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Relationship between IS901 in the Mycobacterium avium complex strains isolated from birds, animals, humans, and the environment and virulence for poultry.

Clin Diagn Lab Immunol. 2000 Mar;7(2):212-7. Unique Identifier : AIDSLINE MED/20169421
Pavlik I; Svastova P; Bartl J; Dvorska L; Rychlik I; Veterinary Research Institute, Hudcova 70, 621 32 Brno, Czech; Republic. pavlik@vri.cz

Abstract: A total of 738 strains of Mycobacterium avium complex (MAC) were examined in biological experiments on poultry by use of PCR methods with primers for detection of the insertion sequence IS901. Serotype strains of MAC from all known 28 serotypes were examined. Further strains were isolated from human immunodeficiency virus (HIV)-negative and HIV-positive patients, 6 animal species, 17 bird species, and the environment. Of 165 strains virulent for poultry, characterized by generalized tuberculosis, 164 strains contained IS901, a result which is statistically highly significant (P, 0.01). The remaining 573 strains were nonvirulent; however, IS901 was present in 24 strains. From among 20 strains of serotypes 1, 2, and 3, IS901 was found in 15 strains, only 5 of which were virulent for poultry. The remaining 111 strains, of serotypes 4 to 28, were nonvirulent and did not incorporate IS901. None of the 152 strains isolated from humans was virulent for poultry, including 12 strains which were IS901 positive.

Keywords: JOURNAL ARTICLE Animal AIDS-Related Opportunistic Infections/MICROBIOLOGY Birds Cattle Chickens *DNA Transposable Elements DNA, Bacterial Goats Horses Human Mycobacterium avium Complex/*CLASSIFICATION/*GENETICS/ PATHOGENICITY Mycobacterium avium-intracellulare Infection/*MICROBIOLOGY/ VETERINARY Poultry Serotyping Sheep Support, Non-U.S. Gov't Swine VirulenceKWDjournalarticleanimalaids-relatedopportunisticinfections/microbiologybirdscattlechickensKWDdnatransposableelementsdna,bacterialgoatshorseshumanmycobacteriumaviumcomplex/KWDclassification/KWDgenetics/pathogenicitymycobacteriumavium-intracellulareinfection/KWDmicrobiology/veterinarypoultryserotypingsheepsupport,non-uKWDsKWDgov'tswinevirulence
000730
A0071450

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