Isolation and amino acid sequence of a peptide with vitellogenesis inhibiting activity from the terrestrial isopod Armadillidium vulgare (Crustacea). NLM AIDSLINE Important note: Information in this article was accurate in 2000. The state of the art may have changed since the publication date.

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Isolation and amino acid sequence of a peptide with vitellogenesis inhibiting activity from the terrestrial isopod Armadillidium vulgare (Crustacea).

Gen Comp Endocrinol. 1999 Sep;115(3):406-14. Unique Identifier : AIDSLINE MED/99412216
Greve P; Sorokine O; Berges T; Lacombe C; Van Dorsselaer A; Martin G; Genetique et Biologie des Populations de Crustaces, UMR CNRS; 6556.

Abstract: The complete amino acid sequence of a neuropeptide was established using gas-phase microsequencing, mass spectrometry, and reverse transcription-polymerase chain reaction. This peptide, stored in the sinus gland of the terrestrial isopod Armadillidium vulgare, inhibited vitellogenin synthesis by the fat tissue and inhibited the onset of secondary vitellogenesis when tested in homologous bioassays. This peptide, named Arv-VIH, has 83 amino acid residues and a molecular mass of 9485 Da. Relationships with other related peptides are presented. Copyright 1999 Academic Press.
Keywords: JOURNAL ARTICLE Amino Acid Sequence Animal Base Sequence Carrier Proteins/*CHEMISTRY/GENETICS Chromatography, High Pressure Liquid Comparative Study Crustacea/*METABOLISM Cyanogen Bromide Female Invertebrate Hormones/CHEMISTRY/GENETICS Male Molecular Sequence Data Neuropeptides/*CHEMISTRY/GENETICS Peptide Fragments/CHEMISTRY Sequence Homology Spectrum Analysis, Mass Trypsin Vitellogenesis/*DRUG EFFECTS

KWDjournalarticleaminoacidsequenceanimalbasesequencecarrierproteins/KWDchemistry/geneticschromatography,highpressureliquidcomparativestudycrustacea/KWDmetabolismcyanogenbromidefemaleinvertebratehormones/chemistry/geneticsmalemolecularsequencedataneuropeptides/KWDchemistry/geneticspeptidefragments/chemistrysequencehomologyspectrumanalysis,masstrypsinvitellogenesis/KWDdrugeffects
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A0010762

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